Published in Proc Natl Acad Sci U S A on April 06, 2010
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Large, stratified, and mechanically functional human cartilage grown in vitro by mesenchymal condensation. Proc Natl Acad Sci U S A (2014) 1.84
Engineering of a functional bone organ through endochondral ossification. Proc Natl Acad Sci U S A (2013) 1.55
Joint morphogenetic cells in the adult mammalian synovium. Nat Commun (2017) 1.46
Enhanced MSC chondrogenesis following delivery of TGF-β3 from alginate microspheres within hyaluronic acid hydrogels in vitro and in vivo. Biomaterials (2011) 1.43
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The effect of hypoxia on the chondrogenic differentiation of co-cultured articular chondrocytes and mesenchymal stem cells in scaffolds. Biomaterials (2013) 1.10
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Metabolic programming of mesenchymal stromal cells by oxygen tension directs chondrogenic cell fate. Proc Natl Acad Sci U S A (2014) 0.99
Dynamic compressive loading enhances cartilage matrix synthesis and distribution and suppresses hypertrophy in hMSC-laden hyaluronic acid hydrogels. Tissue Eng Part A (2011) 0.98
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SnoN suppresses maturation of chondrocytes by mediating signal cross-talk between transforming growth factor-β and bone morphogenetic protein pathways. J Biol Chem (2012) 0.92
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Long-term expansion, enhanced chondrogenic potential, and suppression of endochondral ossification of adult human MSCs via WNT signaling modulation. Stem Cell Reports (2015) 0.88
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Growth differentiation factor-5 enhances in vitro mesenchymal stromal cell chondrogenesis and hypertrophy. Stem Cells Dev (2013) 0.88
Controlling stem cell-mediated bone regeneration through tailored mechanical properties of collagen scaffolds. Biomaterials (2013) 0.84
Thyroid hormone-induced hypertrophy in mesenchymal stem cell chondrogenesis is mediated by bone morphogenetic protein-4. Tissue Eng Part A (2013) 0.82
Bone morphogenic protein (BMP) signaling up-regulates neutral sphingomyelinase 2 to suppress chondrocyte maturation via the Akt protein signaling pathway as a negative feedback mechanism. J Biol Chem (2014) 0.82
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Altering the architecture of tissue engineered hypertrophic cartilaginous grafts facilitates vascularisation and accelerates mineralisation. PLoS One (2014) 0.81
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The effect of low-frequency electromagnetic field on human bone marrow stem/progenitor cell differentiation. Stem Cell Res (2015) 0.80
The effect of dexamethasone and triiodothyronine on terminal differentiation of primary bovine chondrocytes and chondrogenically differentiated mesenchymal stem cells. PLoS One (2013) 0.80
Formation of cartilage and synovial tissue by human gingival stem cells. Stem Cells Dev (2014) 0.80
In vivo ectopic implantation model to assess human mesenchymal progenitor cell potential. Stem Cell Rev (2013) 0.79
Cell-mediated degradation regulates human mesenchymal stem cell chondrogenesis and hypertrophy in MMP-sensitive hyaluronic acid hydrogels. PLoS One (2014) 0.79
In serum veritas-in serum sanitas? Cell non-autonomous aging compromises differentiation and survival of mesenchymal stromal cells via the oxidative stress pathway. Cell Death Dis (2013) 0.79
A novel human TGF-β1 fusion protein in combination with rhBMP-2 increases chondro-osteogenic differentiation of bone marrow mesenchymal stem cells. Int J Mol Sci (2014) 0.79
Osteoinductivity of engineered cartilaginous templates devitalized by inducible apoptosis. Proc Natl Acad Sci U S A (2014) 0.79
Combination of Collagen-Based Scaffold and Bioactive Factors Induces Adipose-Derived Mesenchymal Stem Cells Chondrogenic Differentiation In vitro. Front Physiol (2017) 0.79
Differential gene expression of the intermediate and outer interzone layers of developing articular cartilage in murine embryos. Stem Cells Dev (2014) 0.78
Scaffold-based delivery of a clinically relevant anti-angiogenic drug promotes the formation of in vivo stable cartilage. Tissue Eng Part A (2013) 0.78
Tissue engineering strategies for promoting vascularized bone regeneration. Bone (2015) 0.78
The Necessity of a Systematic Approach for the Use of MSCs in the Clinical Setting. Stem Cells Int (2013) 0.78
Endochondral ossification for enhancing bone regeneration: converging native extracellular matrix biomaterials and developmental engineering in vivo. Tissue Eng Part B Rev (2014) 0.78
Sonic Hedgehog-activated engineered blood vessels enhance bone tissue formation. Proc Natl Acad Sci U S A (2012) 0.78
Stem cell-based bone repair. Am J Stem Cells (2012) 0.78
Expression of BMP and Actin Membrane Bound Inhibitor Is Increased during Terminal Differentiation of MSCs. Stem Cells Int (2016) 0.77
Controlled Dual Growth Factor Delivery From Microparticles Incorporated Within Human Bone Marrow-Derived Mesenchymal Stem Cell Aggregates for Enhanced Bone Tissue Engineering via Endochondral Ossification. Stem Cells Transl Med (2015) 0.77
Total body irradiation is permissive for mesenchymal stem cell-mediated new bone formation following local transplantation. Tissue Eng Part A (2014) 0.77
Generation of a Bone Organ by Human Adipose-Derived Stromal Cells Through Endochondral Ossification. Stem Cells Transl Med (2016) 0.77
Bone-forming capacity of adult human nasal chondrocytes. J Cell Mol Med (2015) 0.77
Tissue Engineering Whole Bones Through Endochondral Ossification: Regenerating the Distal Phalanx. Biores Open Access (2015) 0.77
Novel Perfused Compression Bioreactor System as an in vitro Model to Investigate Fracture Healing. Front Bioeng Biotechnol (2015) 0.76
Cartilage to bone transformation during fracture healing is coordinated by the invading vasculature and induction of the core pluripotency genes. Development (2017) 0.76
High-throughput bone and cartilage micropellet manufacture, followed by assembly of micropellets into biphasic osteochondral tissue. Cell Tissue Res (2015) 0.76
In vitro hypertrophy and calcification of human fracture haematoma-derived cells in chondrogenic differentiation. Int Orthop (2013) 0.76
Promoting Endochondral Bone Repair Using Human Osteoarthritic Articular Chondrocytes. Tissue Eng Part A (2016) 0.75
Role of RHEB in Regulating Differentiation Fate of Mesenchymal Stem Cells for Cartilage and Bone Regeneration. Int J Mol Sci (2017) 0.75
Recapitulation of physiological spatiotemporal signals promotes in vitro formation of phenotypically stable human articular cartilage. Proc Natl Acad Sci U S A (2017) 0.75
Osteogenic Differentiation of Mesenchymal Stem Cells by Mimicking the Cellular Niche of the Endochondral Template. Tissue Eng Part A (2016) 0.75
Extracellular matrix components and culture regimen selectively regulate cartilage formation by self-assembling human mesenchymal stem cells in vitro and in vivo. Stem Cell Res Ther (2016) 0.75
Epiphyseal Chondroprogenitors Provide a Stable Cell Source for Cartilage Cell Therapy. Cell Med (2012) 0.75
SMAD3 and SMAD4 have a more dominant role than SMAD2 in TGFβ-induced chondrogenic differentiation of bone marrow-derived mesenchymal stem cells. Sci Rep (2017) 0.75
Fat-Derived Stromal Vascular Fraction Cells Enhance the Bone-Forming Capacity of Devitalized Engineered Hypertrophic Cartilage Matrix. Stem Cells Transl Med (2016) 0.75
A Qualitative Model of the Differentiation Network in Chondrocyte Maturation: A Holistic View of Chondrocyte Hypertrophy. PLoS One (2016) 0.75
Repair of osteochondral defects with in vitro engineered cartilage based on autologous bone marrow stromal cells in a swine model. Sci Rep (2017) 0.75
Bone Density, Osteocalcin and Deoxypyridinoline for Early Detection of Osteoporosis in Obese Children. Open Access Maced J Med Sci (2015) 0.75
Poly(γ-Glutamic Acid) as an Exogenous Promoter of Chondrogenic Differentiation of Human Mesenchymal Stem/Stromal Cells. Tissue Eng Part A (2015) 0.75
An open source image processing method to quantitatively assess tissue growth after non-invasive magnetic resonance imaging in human bone marrow stromal cell seeded 3D polymeric scaffolds. PLoS One (2014) 0.75
Enamel Matrix Derivative has No Effect on the Chondrogenic Differentiation of Mesenchymal Stem Cells. Front Bioeng Biotechnol (2014) 0.75
Spontaneous In Vivo Chondrogenesis of Bone Marrow-Derived Mesenchymal Progenitor Cells by Blocking Vascular Endothelial Growth Factor Signaling. Stem Cells Transl Med (2016) 0.75
Effects of in vitro endochondral priming and pre-vascularisation of human MSC cellular aggregates in vivo. Stem Cell Res Ther (2015) 0.75
Gelatin device for the delivery of growth factors involved in endochondral ossification. PLoS One (2017) 0.75
Effect of heat treatment on the properties of SiO2-CaO-MgO-P 2O 5 bioactive glasses. J Mater Sci Mater Med (2012) 0.75
Efficacy of Honeycomb TCP-induced Microenvironment on Bone Tissue Regeneration in Craniofacial Area. Int J Med Sci (2016) 0.75
Generation and use of a humanized bone-marrow-ossicle niche for hematopoietic xenotransplantation into mice. Nat Protoc (2017) 0.75
Biomimetic strategies for fracture repair: Engineering the cell microenvironment for directed tissue formation. J Tissue Eng (2017) 0.75
Ontogenic Identification and Analysis of Mesenchymal Stromal Cell Populations during Mouse Limb and Long Bone Development. Stem Cell Reports (2017) 0.75
Bioengineering of Humanized Bone Marrow Microenvironments in Mouse and Their Visualization by Live Imaging. J Vis Exp (2017) 0.75
An Approach to In Vitro Manufacturing of Hypertrophic Cartilage Matrix for Bone Repair. Bioengineering (Basel) (2017) 0.75
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Beyond Wnt inhibition: new functions of secreted Frizzled-related proteins in development and disease. J Cell Sci (2008) 3.21
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Gremlin-mediated BMP antagonism induces the epithelial-mesenchymal feedback signaling controlling metanephric kidney and limb organogenesis. Development (2004) 2.39
Silk matrix for tissue engineered anterior cruciate ligaments. Biomaterials (2002) 2.22
Early detection of aging cartilage and osteoarthritis in mice and patient samples using atomic force microscopy. Nat Nanotechnol (2009) 2.19
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Dual RMCE for efficient re-engineering of mouse mutant alleles. Nat Methods (2010) 2.05
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Angiogenesis in tissue engineering: breathing life into constructed tissue substitutes. Tissue Eng (2006) 1.86
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Synaptopodin-deficient mice lack a spine apparatus and show deficits in synaptic plasticity. Proc Natl Acad Sci U S A (2003) 1.79
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TGF-β-induced differentiation into myofibroblasts involves specific regulation of two MKL1 isoforms. J Cell Sci (2014) 0.97
Interleukin-1β modulates endochondral ossification by human adult bone marrow stromal cells. Eur Cell Mater (2012) 0.97
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Human intronic enhancers control distinct sub-domains of Gli3 expression during mouse CNS and limb development. BMC Dev Biol (2010) 0.95
A Grid-based solution for management and analysis of microarrays in distributed experiments. BMC Bioinformatics (2007) 0.95
Advanced bioreactor with controlled application of multi-dimensional strain for tissue engineering. J Biomech Eng (2002) 0.95
Fibroblast growth factor-2 maintains a niche-dependent population of self-renewing highly potent non-adherent mesenchymal progenitors through FGFR2c. Stem Cells (2012) 0.95
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