Published in Development on September 01, 2006
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An Fgf/Gremlin inhibitory feedback loop triggers termination of limb bud outgrowth. Nature (2008) 1.55
Extended exposure to Sonic hedgehog is required for patterning the posterior digits of the vertebrate limb. Dev Biol (2007) 1.49
Distinct roles of Hand2 in initiating polarity and posterior Shh expression during the onset of mouse limb bud development. PLoS Genet (2010) 1.35
Gremlin 2 regulates distinct roles of BMP and Endothelin 1 signaling in dorsoventral patterning of the facial skeleton. Development (2011) 1.17
The evolution of HoxD-11 expression in the bird wing: insights from Alligator mississippiensis. PLoS One (2008) 1.16
Cross-talk between Notch and Hedgehog regulates hepatic stellate cell fate in mice. Hepatology (2013) 1.07
Sall genes regulate region-specific morphogenesis in the mouse limb by modulating Hox activities. Development (2009) 1.02
Genetic evidence that SOST inhibits WNT signaling in the limb. Dev Biol (2010) 0.98
SHH propagates distal limb bud development by enhancing CYP26B1-mediated retinoic acid clearance via AER-FGF signalling. Development (2011) 0.95
Formin1 disruption confers oligodactylism and alters Bmp signaling. Hum Mol Genet (2009) 0.93
Shh pathway activation is present and required within the vertebrate limb bud apical ectodermal ridge for normal autopod patterning. Proc Natl Acad Sci U S A (2010) 0.92
Conserved cis-regulatory regions in a large genomic landscape control SHH and BMP-regulated Gremlin1 expression in mouse limb buds. BMC Dev Biol (2012) 0.90
FGF8 and SHH substitute for anterior-posterior tissue interactions to induce limb regeneration. Nature (2016) 0.90
DNA binding-dependent and -independent functions of the Hand2 transcription factor during mouse embryogenesis. Development (2009) 0.89
Transitions between epithelial and mesenchymal states during cell fate conversions. Protein Cell (2014) 0.87
Transcriptional regulation of graded Hedgehog signaling. Semin Cell Dev Biol (2014) 0.86
Distinct populations within Isl1 lineages contribute to appendicular and facial skeletogenesis through the β-catenin pathway. Dev Biol (2014) 0.81
A perspective on molecular therapy in cholangiocarcinoma: present status and future directions. Hepat Oncol (2014) 0.81
Molecular anatomy of the developing limb in the coquí frog, Eleutherodactylus coqui. Evol Dev (2012) 0.80
A Gli silencer is required for robust repression of gremlin in the vertebrate limb bud. Development (2014) 0.79
Antagonistic crosstalk of Wnt/beta-catenin/Bmp signaling within the Apical Ectodermal Ridge (AER) regulates interdigit formation. Biochem Biophys Res Commun (2009) 0.77
Spatiotemporal regulation of GLI target genes in the mammalian limb bud. Dev Biol (2015) 0.77
Manipulating gene expression and signaling activity in cultured mouse limb bud cells. Dev Dyn (2014) 0.77
Hedgehog and Wnt coordinate signaling in myogenic progenitors and regulate limb regeneration. Dev Biol (2012) 0.77
The apical ectodermal ridge of the mouse model of ectrodactyly Dlx5;Dlx6-/- shows altered stratification and cell polarity, which are restored by exogenous Wnt5a ligand. Hum Mol Genet (2015) 0.76
Suppressor of Fused Is Required for Determining Digit Number and Identity via Gli3/Fgfs/Gremlin. PLoS One (2015) 0.75
A systems biology approach to defining regulatory mechanisms for cartilage and tendon cell phenotypes. Sci Rep (2016) 0.75
Sonic Hedgehog Signaling in Limb Development. Front Cell Dev Biol (2017) 0.75
An FGF3-BMP Signaling Axis Regulates Caudal Neural Tube Closure, Neural Crest Specification and Anterior-Posterior Axis Extension. PLoS Genet (2016) 0.75
Anteroposterior Limb Skeletal Patterning Requires the Bifunctional Action of SWI/SNF Chromatin Remodeling Complex in Hedgehog Pathway. PLoS Genet (2016) 0.75
Suppressor of Fused Restraint of Hedgehog Activity Level is Critical for Osteogenic Proliferation and Differentiation during Calvarial Bone Development. J Biol Chem (2017) 0.75
John Saunders' ZPA, Sonic hedgehog and digit identity - How does it really all work? Dev Biol (2017) 0.75
The beta-catenin/TCF-4 complex imposes a crypt progenitor phenotype on colorectal cancer cells. Cell (2002) 13.92
Hematoxylin and eosin staining of tissue and cell sections. CSH Protoc (2008) 2.80
Progression of vertebrate limb development through SHH-mediated counteraction of GLI3. Science (2002) 2.45
Gremlin-mediated BMP antagonism induces the epithelial-mesenchymal feedback signaling controlling metanephric kidney and limb organogenesis. Development (2004) 2.39
Tissue remodelling through branching morphogenesis. Nat Rev Mol Cell Biol (2009) 2.06
Dual RMCE for efficient re-engineering of mouse mutant alleles. Nat Methods (2010) 2.05
Recapitulation of endochondral bone formation using human adult mesenchymal stem cells as a paradigm for developmental engineering. Proc Natl Acad Sci U S A (2010) 1.96
Synaptopodin-deficient mice lack a spine apparatus and show deficits in synaptic plasticity. Proc Natl Acad Sci U S A (2003) 1.79
Transparency in Research involving Animals: The Basel Declaration and new principles for reporting research in BJP manuscripts. Br J Pharmacol (2015) 1.79
Reduction of BMP4 activity by gremlin 1 enables ureteric bud outgrowth and GDNF/WNT11 feedback signalling during kidney branching morphogenesis. Development (2007) 1.72
Mutual genetic antagonism involving GLI3 and dHAND prepatterns the vertebrate limb bud mesenchyme prior to SHH signaling. Genes Dev (2002) 1.61
Mouse limb deformity mutations disrupt a global control region within the large regulatory landscape required for Gremlin expression. Genes Dev (2004) 1.60
A self-regulatory system of interlinked signaling feedback loops controls mouse limb patterning. Science (2009) 1.58
Distinct roles of Hand2 in initiating polarity and posterior Shh expression during the onset of mouse limb bud development. PLoS Genet (2010) 1.35
Vertebrate limb development: moving from classical morphogen gradients to an integrated 4-dimensional patterning system. Cold Spring Harb Perspect Biol (2009) 1.31
Paraffin embedding tissue samples for sectioning. CSH Protoc (2008) 1.18
Ultraconserved non-coding sequence element controls a subset of spatiotemporal GLI3 expression. Dev Growth Differ (2007) 1.16
Wnt/β-catenin signaling in the dental mesenchyme regulates incisor development by regulating Bmp4. Dev Biol (2010) 1.15
Mouse Twist is required for fibroblast growth factor-mediated epithelial-mesenchymal signalling and cell survival during limb morphogenesis. Mech Dev (2002) 1.08
Caenorhabditis elegans chromatin-associated proteins SET-2 and ASH-2 are differentially required for histone H3 Lys 4 methylation in embryos and adult germ cells. Proc Natl Acad Sci U S A (2011) 1.08
GLI3 constrains digit number by controlling both progenitor proliferation and BMP-dependent exit to chondrogenesis. Dev Cell (2012) 1.07
Reduced mobility of fibroblast growth factor (FGF)-deficient myoblasts might contribute to dystrophic changes in the musculature of FGF2/FGF6/mdx triple-mutant mice. Mol Cell Biol (2003) 1.03
SHH propagates distal limb bud development by enhancing CYP26B1-mediated retinoic acid clearance via AER-FGF signalling. Development (2011) 0.95
The molecular basis of human congenital limb malformations. Wiley Interdiscip Rev Dev Biol (2012) 0.95
Glypican 4 modulates FGF signalling and regulates dorsoventral forebrain patterning in Xenopus embryos. Development (2003) 0.95
Protease nexin 1 and its receptor LRP modulate SHH signalling during cerebellar development. Development (2007) 0.92
Liver regeneration in FGF-2-deficient mice: VEGF acts as potential functional substitute for FGF-2. Liver Int (2004) 0.92
Smad4 is required to induce digit ray primordia and to initiate the aggregation and differentiation of chondrogenic progenitors in mouse limb buds. Development (2012) 0.91
Conserved cis-regulatory regions in a large genomic landscape control SHH and BMP-regulated Gremlin1 expression in mouse limb buds. BMC Dev Biol (2012) 0.90
Genetic interaction of Gli3 and Alx4 during limb development. Int J Dev Biol (2005) 0.90
Glypicans are differentially expressed during patterning and neurogenesis of early mouse brain. Biochem Biophys Res Commun (2006) 0.88
Islet1 regulates establishment of the posterior hindlimb field upstream of the Hand2-Shh morphoregulatory gene network in mouse embryos. Development (2012) 0.87
Regulation of extra-embryonic endoderm stem cell differentiation by Nodal and Cripto signaling. Development (2011) 0.86
Cryosectioning tissues. CSH Protoc (2008) 0.85
Cutting sections of paraffin-embedded tissues. CSH Protoc (2008) 0.85
Patterning the limb before and after SHH signalling. J Anat (2003) 0.84
The hedgehog target Vlk genetically interacts with Gli3 to regulate chondrocyte differentiation during mouse long bone development. Differentiation (2013) 0.82
Genetic analysis reveals an unexpected role of BMP7 in initiation of ureteric bud outgrowth in mouse embryos. PLoS One (2011) 0.82
Fixation and permeabilization of cells and tissues. CSH Protoc (2008) 0.81
1 Patterning the limb before and after SHH. J Anat (2002) 0.80
Making sense-data-based simulations of vertebrate limb development. Curr Opin Genet Dev (2012) 0.79
Rapid conversion of EUCOMM/KOMP-CSD alleles in mouse embryos using a cell-permeable Cre recombinase. Transgenic Res (2013) 0.79
Developmental biology: first come, first served. Nature (2002) 0.78
Dual requirement of ectodermal Smad4 during AER formation and termination of feedback signaling in mouse limb buds. Genesis (2013) 0.78
Preparation of slides and coverslips for microscopy. CSH Protoc (2008) 0.78
From cells to organs: new insight into organ morphogenesis. Curr Opin Genet Dev (2009) 0.77
Mounting live cells attached to coverslips for microscopy. CSH Protoc (2008) 0.77
FGF2 signaling is required for the development of neuronal circuits regulating blood pressure. Circ Res (2002) 0.76
Decalcifying tissues for paraffin embedding. CSH Protoc (2008) 0.75
Media for mounting fixed cells on microscope slides. CSH Protoc (2008) 0.75