Published in Development on March 21, 2012
Genome-wide association study and meta-analysis identify ISL1 as genome-wide significant susceptibility gene for bladder exstrophy. PLoS Genet (2015) 0.93
Hox5 interacts with Plzf to restrict Shh expression in the developing forelimb. Proc Natl Acad Sci U S A (2013) 0.84
Sall4-Gli3 system in early limb progenitors is essential for the development of limb skeletal elements. Proc Natl Acad Sci U S A (2015) 0.83
Sirenomelia phenotype in bmp7;shh compound mutants: a novel experimental model for studies of caudal body malformations. PLoS One (2012) 0.83
Islet1 deletion causes kidney agenesis and hydroureter resembling CAKUT. J Am Soc Nephrol (2013) 0.82
Distinct populations within Isl1 lineages contribute to appendicular and facial skeletogenesis through the β-catenin pathway. Dev Biol (2014) 0.81
Specification of jaw identity by the Hand2 transcription factor. Sci Rep (2016) 0.80
How the embryo makes a limb: determination, polarity and identity. J Anat (2015) 0.75
Multipotent embryonic isl1+ progenitor cells lead to cardiac, smooth muscle, and endothelial cell diversification. Cell (2006) 7.21
A myocardial lineage derives from Tbx18 epicardial cells. Nature (2008) 6.15
Myofibroblasts revert to an inactive phenotype during regression of liver fibrosis. Proc Natl Acad Sci U S A (2012) 3.90
The renewal and differentiation of Isl1+ cardiovascular progenitors are controlled by a Wnt/beta-catenin pathway. Cell Stem Cell (2007) 3.54
Epicardial retinoid X receptor alpha is required for myocardial growth and coronary artery formation. Proc Natl Acad Sci U S A (2005) 3.13
Islet 1 is expressed in distinct cardiovascular lineages, including pacemaker and coronary vascular cells. Dev Biol (2006) 2.81
Hematoxylin and eosin staining of tissue and cell sections. CSH Protoc (2008) 2.80
Activation of Notch signaling pathway precedes heart regeneration in zebrafish. Proc Natl Acad Sci U S A (2003) 2.77
Notch activity acts as a sensor for extracellular calcium during vertebrate left-right determination. Nature (2004) 2.63
Progression of vertebrate limb development through SHH-mediated counteraction of GLI3. Science (2002) 2.45
Gremlin-mediated BMP antagonism induces the epithelial-mesenchymal feedback signaling controlling metanephric kidney and limb organogenesis. Development (2004) 2.39
A central role for Islet1 in sensory neuron development linking sensory and spinal gene regulatory programs. Nat Neurosci (2008) 2.36
Nanog binds to Smad1 and blocks bone morphogenetic protein-induced differentiation of embryonic stem cells. Proc Natl Acad Sci U S A (2006) 2.10
Tissue remodelling through branching morphogenesis. Nat Rev Mol Cell Biol (2009) 2.06
Dual RMCE for efficient re-engineering of mouse mutant alleles. Nat Methods (2010) 2.05
Recapitulation of endochondral bone formation using human adult mesenchymal stem cells as a paradigm for developmental engineering. Proc Natl Acad Sci U S A (2010) 1.96
Distinct origins and genetic programs of head muscle satellite cells. Dev Cell (2009) 1.86
Loss of enigma homolog protein results in dilated cardiomyopathy. Circ Res (2010) 1.85
Resident fibroblast lineages mediate pressure overload-induced cardiac fibrosis. J Clin Invest (2014) 1.82
Beta-catenin directly regulates Islet1 expression in cardiovascular progenitors and is required for multiple aspects of cardiogenesis. Proc Natl Acad Sci U S A (2007) 1.80
Synaptopodin-deficient mice lack a spine apparatus and show deficits in synaptic plasticity. Proc Natl Acad Sci U S A (2003) 1.79
Transparency in Research involving Animals: The Basel Declaration and new principles for reporting research in BJP manuscripts. Br J Pharmacol (2015) 1.79
Regulation of primary cilia formation and left-right patterning in zebrafish by a noncanonical Wnt signaling mediator, duboraya. Nat Genet (2006) 1.76
Hidden breast cancer disparities in Asian women: disaggregating incidence rates by ethnicity and migrant status. Am J Public Health (2010) 1.76
Wnt/beta-catenin signaling regulates vertebrate limb regeneration. Genes Dev (2006) 1.74
Reduction of BMP4 activity by gremlin 1 enables ureteric bud outgrowth and GDNF/WNT11 feedback signalling during kidney branching morphogenesis. Development (2007) 1.72
Antagonism between retinoic acid and fibroblast growth factor signaling during limb development. Cell Rep (2013) 1.65
Development of the cardiac conduction system as delineated by minK-lacZ. J Cardiovasc Electrophysiol (2003) 1.65
Nkx2-5(+)islet1(+) mesenchymal precursors generate distinct spleen stromal cell subsets and participate in restoring stromal network integrity. Immunity (2013) 1.62
Mutual genetic antagonism involving GLI3 and dHAND prepatterns the vertebrate limb bud mesenchyme prior to SHH signaling. Genes Dev (2002) 1.61
Mouse limb deformity mutations disrupt a global control region within the large regulatory landscape required for Gremlin expression. Genes Dev (2004) 1.60
Modulation of morphogenesis by noncanonical Wnt signaling requires ATF/CREB family-mediated transcriptional activation of TGFbeta2. Nat Genet (2007) 1.59
A self-regulatory system of interlinked signaling feedback loops controls mouse limb patterning. Science (2009) 1.58
Notch activity induces Nodal expression and mediates the establishment of left-right asymmetry in vertebrate embryos. Genes Dev (2003) 1.57
Noncanonical Wnt signaling regulates midline convergence of organ primordia during zebrafish development. Genes Dev (2005) 1.51
Tbx20 regulates a genetic program essential to adult mouse cardiomyocyte function. J Clin Invest (2011) 1.46
Subepicardial endothelial cells invade the embryonic ventricle wall to form coronary arteries. Cell Res (2013) 1.46
Scl represses cardiomyogenesis in prospective hemogenic endothelium and endocardium. Cell (2012) 1.43
Coordination of heart and lung co-development by a multipotent cardiopulmonary progenitor. Nature (2013) 1.42
Distinct roles of Hand2 in initiating polarity and posterior Shh expression during the onset of mouse limb bud development. PLoS Genet (2010) 1.35
Islet-1 is required for the maturation, proliferation, and survival of the endocrine pancreas. Diabetes (2009) 1.33
Dosage-dependent hedgehog signals integrated with Wnt/beta-catenin signaling regulate external genitalia formation as an appendicular program. Development (2009) 1.31
Vertebrate limb development: moving from classical morphogen gradients to an integrated 4-dimensional patterning system. Cold Spring Harb Perspect Biol (2009) 1.31
Sp8 exhibits reciprocal induction with Fgf8 but has an opposing effect on anterior-posterior cortical area patterning. Neural Dev (2007) 1.30
The contribution of Islet1-expressing splanchnic mesoderm cells to distinct branchiomeric muscles reveals significant heterogeneity in head muscle development. Development (2008) 1.29
The limb identity gene Tbx5 promotes limb initiation by interacting with Wnt2b and Fgf10. Development (2002) 1.29
BMP-3 and BMP-6 structures illuminate the nature of binding specificity with receptors. Biochemistry (2007) 1.27
Tbx2 and Tbx3 regulate the dynamics of cell proliferation during heart remodeling. PLoS One (2007) 1.26
Diagnosis of gastric cancer with MDCT using the water-filling method and multiplanar reconstruction: CT-histologic correlation. AJR Am J Roentgenol (2005) 1.24
Expression of the hyperpolarization-activated cyclic nucleotide-gated cation channel HCN4 during mouse heart development. Gene Expr Patterns (2003) 1.24
The influence of nativity and neighborhoods on breast cancer stage at diagnosis and survival among California Hispanic women. BMC Cancer (2010) 1.23
Differential regulation of gene expression in the digit forming area of the mouse limb bud by SHH and gremlin 1/FGF-mediated epithelial-mesenchymal signalling. Development (2006) 1.22
Islet-to-LMO stoichiometries control the function of transcription complexes that specify motor neuron and V2a interneuron identity. Development (2009) 1.19
T-Box transcription factor Tbx20 regulates a genetic program for cranial motor neuron cell body migration. Development (2006) 1.18
Coxsackievirus and adenovirus receptor (CAR) mediates atrioventricular-node function and connexin 45 localization in the murine heart. J Clin Invest (2008) 1.18
Paraffin embedding tissue samples for sectioning. CSH Protoc (2008) 1.18
A Src-Tks5 pathway is required for neural crest cell migration during embryonic development. PLoS One (2011) 1.16
Ultraconserved non-coding sequence element controls a subset of spatiotemporal GLI3 expression. Dev Growth Differ (2007) 1.16
Wnt/β-catenin signaling in the dental mesenchyme regulates incisor development by regulating Bmp4. Dev Biol (2010) 1.15
Maintenance of embryonic stem cell pluripotency by Nanog-mediated reversal of mesoderm specification. Nat Clin Pract Cardiovasc Med (2006) 1.15
The heart endocardium is derived from vascular endothelial progenitors. Development (2011) 1.13
Mouse Twist is required for fibroblast growth factor-mediated epithelial-mesenchymal signalling and cell survival during limb morphogenesis. Mech Dev (2002) 1.08
Dual transcriptional activator and repressor roles of TBX20 regulate adult cardiac structure and function. Hum Mol Genet (2012) 1.08
Targeted ablation of PINCH1 and PINCH2 from murine myocardium results in dilated cardiomyopathy and early postnatal lethality. Circulation (2009) 1.08
Neural tube defects associated with maternal periconceptional dietary intake of simple sugars and glycemic index. Am J Clin Nutr (2003) 1.08
GLI3 constrains digit number by controlling both progenitor proliferation and BMP-dependent exit to chondrogenesis. Dev Cell (2012) 1.07
Pharyngeal mesoderm development during embryogenesis: implications for both heart and head myogenesis. Cardiovasc Res (2011) 1.06
Localization of Islet-1-positive cells in the healthy and infarcted adult murine heart. Circ Res (2012) 1.06
Thymosin beta 4 is dispensable for murine cardiac development and function. Circ Res (2011) 1.05
Differential diagnosis between (18)F-FDG-avid metastatic lymph nodes in non-small cell lung cancer and benign nodes on dual-time point PET/CT scan. Ann Nucl Med (2009) 1.04
Effect of polyethylene glycol linker chain length of folate-linked microemulsions loading aclacinomycin A on targeting ability and antitumor effect in vitro and in vivo. Clin Cancer Res (2005) 1.03
Migration of cardiomyocytes is essential for heart regeneration in zebrafish. Development (2012) 1.03
Reduced mobility of fibroblast growth factor (FGF)-deficient myoblasts might contribute to dystrophic changes in the musculature of FGF2/FGF6/mdx triple-mutant mice. Mol Cell Biol (2003) 1.03
Sall genes regulate region-specific morphogenesis in the mouse limb by modulating Hox activities. Development (2009) 1.02
Residential proximity to agricultural pesticide use and incidence of breast cancer in California, 1988-1997. Environ Health Perspect (2005) 1.02
miles-apart-Mediated regulation of cell-fibronectin interaction and myocardial migration in zebrafish. Nat Clin Pract Cardiovasc Med (2007) 1.01
Chromatin protein HMGB2 regulates articular cartilage surface maintenance via beta-catenin pathway. Proc Natl Acad Sci U S A (2009) 0.99
The zebrafish as a model of heart regeneration. Cloning Stem Cells (2004) 0.97
Trihalomethane exposures from municipal water supplies and selected congenital malformations. Epidemiology (2003) 0.96
Lymphatic drainage from esophagogastric tract: feasibility of endoscopic CT lymphography for direct visualization of pathways. Radiology (2005) 0.96
Designer TGFβ superfamily ligands with diversified functionality. PLoS One (2011) 0.96
SHH propagates distal limb bud development by enhancing CYP26B1-mediated retinoic acid clearance via AER-FGF signalling. Development (2011) 0.95
Glypican 4 modulates FGF signalling and regulates dorsoventral forebrain patterning in Xenopus embryos. Development (2003) 0.95
The molecular basis of human congenital limb malformations. Wiley Interdiscip Rev Dev Biol (2012) 0.95
Life-long preservation of the regenerative capacity in the fin and heart in zebrafish. Biol Open (2012) 0.94
Avian intervertebral disc arises from rostral sclerotome and lacks a nucleus pulposus: implications for evolution of the vertebrate disc. Dev Dyn (2012) 0.93
Cardiac fibroblasts: from development to heart failure. J Mol Med (Berl) (2015) 0.93
Dual-time point 18F-FDG PET/CT scan for differentiation between 18F-FDG-avid non-small cell lung cancer and benign lesions. Ann Nucl Med (2009) 0.93
β-Catenin signaling specifies progenitor cell identity in parallel with Shh signaling in the developing mammalian thalamus. Development (2012) 0.93
Cell lineage transport: a mechanism for molecular gradient formation. Mol Syst Biol (2006) 0.93
Selective deletion of long but not short Cypher isoforms leads to late-onset dilated cardiomyopathy. Hum Mol Genet (2011) 0.92
Liver regeneration in FGF-2-deficient mice: VEGF acts as potential functional substitute for FGF-2. Liver Int (2004) 0.92
Papillary thyroid cancer incidence rates vary significantly by birthplace in Asian American women. Cancer Causes Control (2011) 0.92
Protease nexin 1 and its receptor LRP modulate SHH signalling during cerebellar development. Development (2007) 0.92
Isl1 is required for multiple aspects of motor neuron development. Mol Cell Neurosci (2011) 0.92