Antibodies to nerve growth factor reverse established tactile allodynia in rodent models of neuropathic pain without tolerance.

PubWeight™: 1.11‹?› | Rank: Top 10%

🔗 View Article (PMID 17431136)

Published in J Pharmacol Exp Ther on April 12, 2007

Authors

Kenneth D Wild1, Di Bian, Dawn Zhu, James Davis, Anthony W Bannon, Tie J Zhang, Jean-Claude Louis

Author Affiliations

1: Department of Neuroscience, Amgen Inc., MS-29-2-B, 1 Amgen Center Drive, Thousand Oaks, CA 91320-1799, USA. kwild@amgen.com

Articles citing this

IL-6- and NGF-induced rapid control of protein synthesis and nociceptive plasticity via convergent signaling to the eIF4F complex. J Neurosci (2010) 1.52

Targeting adenosine monophosphate-activated protein kinase (AMPK) in preclinical models reveals a potential mechanism for the treatment of neuropathic pain. Mol Pain (2011) 1.32

Blockade of NGF and trk receptors inhibits increased peripheral mechanical sensitivity accompanying cystitis in rats. Am J Physiol Regul Integr Comp Physiol (2008) 1.21

Abnormal sympathetic nervous system development and physiological dysautonomia in Egr3-deficient mice. Development (2008) 1.19

Nerve growth factor mediates mechanical allodynia in a mouse model of type 2 diabetes. J Neuropathol Exp Neurol (2009) 1.06

p38 mediates mechanical allodynia in a mouse model of type 2 diabetes. Mol Pain (2010) 0.99

Expression profile of nerve growth factor after muscle incision in the rat. Anesthesiology (2009) 0.98

Intrathecal NGF administration reduces reactive astrocytosis and changes neurotrophin receptors expression pattern in a rat model of neuropathic pain. Cell Mol Neurobiol (2009) 0.98

Emerging drugs for osteoarthritis. Expert Opin Emerg Drugs (2011) 0.96

Nerve growth factor/p38 signaling increases intraepidermal nerve fiber densities in painful neuropathy of type 2 diabetes. Neurobiol Dis (2011) 0.93

Role of neurotrophins in neuropathic pain. Curr Neuropharmacol (2011) 0.90

Enkephalin-encoding herpes simplex virus-1 decreases inflammation and hotplate sensitivity in a chronic pancreatitis model. Mol Pain (2008) 0.89

Fulranumab for treatment of diabetic peripheral neuropathic pain: A randomized controlled trial. Neurology (2014) 0.85

Anti-nerve growth factor in pain management: current evidence. J Pain Res (2016) 0.84

Involvement of Tyr1472 phosphorylation of NMDA receptor NR2B subunit in postherpetic neuralgia in model mice. Mol Pain (2012) 0.81

Repeated muscle injury as a presumptive trigger for chronic masticatory muscle pain. Pain Res Treat (2011) 0.81

Intra-articular nerve growth factor regulates development, but not maintenance, of injury-induced facet joint pain & spinal neuronal hypersensitivity. Osteoarthritis Cartilage (2015) 0.79

Temporal mismatch between pain behaviour, skin Nerve Growth factor and intra-epidermal nerve fibre density in trigeminal neuropathic pain. BMC Neurosci (2014) 0.78

The Complement System Component C5a Produces Thermal Hyperalgesia via Macrophage-to-Nociceptor Signaling That Requires NGF and TRPV1. J Neurosci (2016) 0.77

Safety, tolerability, pharmacokinetics, and efficacy of AMG 403, a human anti-nerve growth factor monoclonal antibody, in two phase I studies with healthy volunteers and knee osteoarthritis subjects. Arthritis Res Ther (2015) 0.76

The efficacy of nerve growth factor antibody in a mouse model of neuropathic cancer pain. Exp Anim (2016) 0.75

Activation of neurotrophins in lumbar dorsal root probably contributes to neuropathic pain after spinal nerve ligation. Iran J Basic Med Sci (2017) 0.75

Fulranumab in Patients With Pain Associated With Postherpetic Neuralgia and Postraumatic Neuropathy: Efficacy, Safety, and Tolerability Results From a Randomized, Double-blind, Placebo-controlled, Phase-2 Study. Clin J Pain (2017) 0.75

The TrkA receptor mediates experimental thermal hyperalgesia produced by nerve growth factor: Modulation by the p75 neurotrophin receptor. Neuroscience (2016) 0.75

Nerve growth factor inhibitor with novel-binding domain demonstrates nanomolar efficacy in both cell-based and cell-free assay systems. Pharmacol Res Perspect (2017) 0.75

Depletion of nerve growth factor in chemotherapy-induced peripheral neuropathy associated with hematologic malignancies. PLoS One (2017) 0.75

Articles by these authors

Nonthermal activation of transient receptor potential vanilloid-1 channels in abdominal viscera tonically inhibits autonomic cold-defense effectors. J Neurosci (2007) 2.57

FGF23 neutralization improves chronic kidney disease-associated hyperparathyroidism yet increases mortality. J Clin Invest (2012) 2.41

Inhibition of neuropathic pain by decreased expression of the tetrodotoxin-resistant sodium channel, NaV1.8. Pain (2002) 2.24

Molecular determinants of vanilloid sensitivity in TRPV1. J Biol Chem (2004) 2.17

AMG 9810 [(E)-3-(4-t-butylphenyl)-N-(2,3-dihydrobenzo[b][1,4] dioxin-6-yl)acrylamide], a novel vanilloid receptor 1 (TRPV1) antagonist with antihyperalgesic properties. J Pharmacol Exp Ther (2004) 2.08

The vanilloid receptor TRPV1 is tonically activated in vivo and involved in body temperature regulation. J Neurosci (2007) 2.07

Impaired coordination of nutrient intake and substrate oxidation in melanocortin-4 receptor knockout mice. Endocrinology (2003) 1.49

Sodium channels and nociception: recent concepts and therapeutic opportunities. Curr Opin Pharmacol (2007) 1.41

Protective effects of dietary antioxidants on proton total-body irradiation-mediated hematopoietic cell and animal survival. Radiat Res (2009) 1.31

Cocaine- and amphetamine-related transcript is involved in the orexigenic effect of endogenous anandamide. Neuroendocrinology (2005) 1.26

Antihyperalgesic effects of (R,E)-N-(2-hydroxy-2,3-dihydro-1H-inden-4-yl)-3-(2-(piperidin-1-yl)-4-(trifluoromethyl)phenyl)-acrylamide (AMG8562), a novel transient receptor potential vanilloid type 1 modulator that does not cause hyperthermia in rats. J Pharmacol Exp Ther (2008) 1.21

Repeated administration of vanilloid receptor TRPV1 antagonists attenuates hyperthermia elicited by TRPV1 blockade. J Pharmacol Exp Ther (2007) 1.20

Targeted deletion of melanocortin receptor subtypes 3 and 4, but not CART, alters nutrient partitioning and compromises behavioral and metabolic responses to leptin. FASEB J (2005) 1.15

Dietary antioxidants protect hematopoietic cells and improve animal survival after total-body irradiation. Radiat Res (2008) 1.09

The influence of community and individual health literacy on self-reported health status. J Gen Intern Med (2013) 1.09

Antihypertensive adherence and drug class among Asian Pacific Americans. Ethn Health (2007) 1.08

Western Trauma Association critical decisions in trauma: nonoperative management of adult blunt hepatic trauma. J Trauma (2009) 1.07

Proton activation does not alter antagonist interaction with the capsaicin-binding pocket of TRPV1. Mol Pharmacol (2005) 1.02

Cultivating engaged leadership through a learning collaborative: lessons from primary care renewal in Oregon safety net clinics. Ann Fam Med (2013) 1.00

Teaching and learning evidence-based medicine in complementary, allied, and alternative health care: an integrated tailor-made course. J Altern Complement Med (2007) 0.99

Cocaine- and amphetamine-regulated transcript (CART) peptides modulate the locomotor and motivational properties of psychostimulants. J Pharmacol Exp Ther (2005) 0.99

Socioeconomic disparities in breast cancer screening in Hawaii. Prev Chronic Dis (2007) 0.99

Self identity through Ho'oponopono as adjunctive therapy for hypertension management. Ethn Dis (2007) 0.98

Regulation of protein catabolism by muscle-specific and cytokine-inducible ubiquitin ligase E3alpha-II during cancer cachexia. Cancer Res (2004) 0.97

Reported lifetime aberrant drug-taking behaviors are predictive of current substance use and mental health problems in primary care patients. Pain Med (2008) 0.97

Followup after an emergency department visit for asthma: urban/rural patterns. Ethn Dis (2008) 0.96

Colorectal cancer screening: low health literacy and limited English proficiency among Asians and Whites in California. J Health Commun (2013) 0.96

Is evidence-based medicine teaching and learning directed at improving practice? J R Soc Med (2010) 0.94

A polyclonal antibody to the prepore loop of transient receptor potential vanilloid type 1 blocks channel activation. J Pharmacol Exp Ther (2006) 0.92

Missed well-child care visits, low continuity of care, and risk of ambulatory care-sensitive hospitalizations in young children. Arch Pediatr Adolesc Med (2010) 0.92

Approaching intelligent infection diagnostics: Carbon fibre sensor for electrochemical pyocyanin detection. Bioelectrochemistry (2009) 0.91

Cathodic reduction of bisulfite and sulfur dioxide in aqueous solutions on copper electrodes: an electrochemical ESR study. J Phys Chem B (2005) 0.91

Design and synthesis of peripherally restricted transient receptor potential vanilloid 1 (TRPV1) antagonists. J Med Chem (2008) 0.91

Manganese detection in marine sediments: anodic vs. cathodic stripping voltammetry. Talanta (2005) 0.91

The calcimimetic AMG 641 abrogates parathyroid hyperplasia, bone and vascular calcification abnormalities in uremic rats. Eur J Pharmacol (2009) 0.90

Use of the dietary supplement 5-aminiolevulinic acid (5-ALA) and its relationship with glucose levels and hemoglobin A1C among individuals with prediabetes. Clin Transl Sci (2012) 0.90

Acute ethanol intoxication and the trauma patient: hemodynamic pitfalls. World J Surg (2011) 0.90

Factors Affecting Sustained Medication Adherence and Its Impact on Health Care Utilization in Patients with Diabetes. J Pharm Health Serv Res (2013) 0.88

A novel selective and orally bioavailable Nav 1.8 channel blocker, PF-01247324, attenuates nociception and sensory neuron excitability. Br J Pharmacol (2015) 0.88

Over-the-counter cold medications-postmortem findings in infants and the relationship to cause of death. J Anal Toxicol (2005) 0.87

Addressing oral health disparities in settings without a research-intensive dental school: collaborative strategies. Ethn Dis (2005) 0.86

iPads, droids, and bugs: Infection prevention for mobile handheld devices at the point of care. Am J Infect Control (2013) 0.86

Perspectives of Chuukese patients and their health care providers on the use of different sources of interpreters. Hawaii J Med Public Health (2012) 0.85

Subcortical and cortical structural central nervous system changes and attention processing deficits in preschool-aged children with prenatal methamphetamine and tobacco exposure. Dev Neurosci (2012) 0.84

Indomethacin-related leukocytoclastic vasculitis: a case report and review of literature. Case Rep Dermatol (2013) 0.84

Screening rates and characteristics of health plan members who respond to screening reminders. Prev Chronic Dis (2006) 0.84

Persistent ovarian masses and pregnancy outcomes. J Matern Fetal Neonatal Med (2013) 0.84

Surgical management of stress urinary incontinence: a questionnaire based survey. Eur Urol (2005) 0.83

Australian nurses' and midwives' knowledge of computers and their attitudes to using them in their practice. J Adv Nurs (2003) 0.83

Maternal pelvic size, measured by dual energy X-ray absorptiometry, predicts infant birthweight. Am J Hum Biol (2000) 0.83

Evaluating education in evidence-based practice. JAMA (2007) 0.83

Novel vanilloid receptor-1 antagonists: 2. Structure-activity relationships of 4-oxopyrimidines leading to the selection of a clinical candidate. J Med Chem (2007) 0.83

The chiropractic care of children with attention-deficit/hyperactivity disorder: a retrospective case series. Explore (NY) (2010) 0.82

The chiropractic care of children with "growing pains": a case series and systematic review of the literature. Complement Ther Clin Pract (2011) 0.81

Malignant neuroendocrine tumors: incidence and outcomes in pediatric patients. Eur J Pediatr Surg (2013) 0.81

Cinacalcet HCl prevents development of parathyroid gland hyperplasia and reverses established parathyroid gland hyperplasia in a rodent model of CKD. Nephrol Dial Transplant (2011) 0.81

Rapid growth from 12 to 23 months of life predicts obesity in a population of Pacific Island children. Ethn Dis (2012) 0.81

Clinical diagnostics for homocysteine: a rogue amino acid? Expert Rev Mol Diagn (2010) 0.81

Factors associated with place of death for elderly Japanese-American men: the Honolulu Heart Program and Honolulu-Asia Aging Study. J Am Geriatr Soc (2009) 0.81

Publishing a medical book: authorship from a medical student perspective. Med Teach (2014) 0.81

Incident neuropathy in HIV-infected patients on HAART. AIDS Res Hum Retroviruses (2010) 0.80

Discovery of a calcimimetic with differential effects on parathyroid hormone and calcitonin secretion. J Pharmacol Exp Ther (2011) 0.80

A chromatographic tool for preparing combinatorial quinone-thiol conjugate libraries. J Biochem Biophys Methods (2007) 0.80

Faculty and resident perceptions regarding overnight student call during the third year OB/GYN clerkship. Hawaii Med J (2011) 0.79

Advances in the voltammetric analysis of small biologically relevant compounds. Anal Biochem (2002) 0.79

The Multiple Sleep Latency Test in the diagnosis of narcolepsy. Am J Psychiatry (2005) 0.79

Pediatric sciatic neuropathy associated with neoplasms. Muscle Nerve (2011) 0.79

An electrochemical adaptation of Ellman's test. Analyst (2002) 0.79

Initial antihypertensive prescriptions, switching patterns and adherence among insured patients in Hawai'i. Hawaii Med J (2008) 0.79

Western Trauma Association critical decisions in trauma: management of the mangled extremity. J Trauma Acute Care Surg (2012) 0.79

The impact of seeing physicians new to a patient on the response to screening reminders. Med Care (2006) 0.79

Prevalence of breastfeeding among a multiethnic population in Hawaii. Ethn Dis (2008) 0.78

A comparison of different types of gold-carbon composite electrode for detection of arsenic(III). Anal Bioanal Chem (2004) 0.78

A novel electroreduction strategy for the determination of sulfite. Analyst (2005) 0.78

Rapid assessment of the latent hazard posed by dissolved mercaptans within aqueous effluent. J Hazard Mater (2007) 0.78

A disposable sensor for point of care wound pH monitoring. Analyst (2011) 0.78

Traumatic brain injury: outcomes from rural and urban locations over a 5-year period (Part 1). Hawaii Med J (2007) 0.78

Design of potent, orally available antagonists of the transient receptor potential vanilloid 1. Structure-activity relationships of 2-piperazin-1-yl-1H-benzimidazoles. J Med Chem (2006) 0.78

Novel vanilloid receptor-1 antagonists: 3. The identification of a second-generation clinical candidate with improved physicochemical and pharmacokinetic properties. J Med Chem (2007) 0.78

Liver disease among children in Hawai'i diagnosed with metabolic syndrome. Hawaii J Med Public Health (2013) 0.77

Combining quality improvement and geriatrics training: the nursing home polypharmacy outcomes project. Gerontol Geriatr Educ (2014) 0.77

A safety-net antibiotic prescription for otitis media: the effects of a PBRN study on patients and practitioners. Clin Pediatr (Phila) (2006) 0.77

The discovery of an orally efficacious positive allosteric modulator of the calcium sensing receptor containing a dibenzylamine core. Bioorg Med Chem Lett (2010) 0.77

Journal Club: Twitter as a source of vaccination information: content drivers and what they're saying. Am J Infect Control (2013) 0.77

INCB38579, a novel and potent histamine H₄ receptor small molecule antagonist with anti-inflammatory pain and anti-pruritic functions. Eur J Pharmacol (2011) 0.77

Current strategies in nitrite detection and their application to field analysis. J Environ Monit (2002) 0.76

Preferred smoking cessation methods for Asian or Pacific Islander household smokers who live with hospitalized children. Hawaii Med J (2011) 0.76

Melanocortin subtype-4 receptor agonists containing a piperazine core with substituted aryl sulfonamides. Bioorg Med Chem Lett (2005) 0.76

Discovery and optimization of substituted 1-(1-phenyl-1H-pyrazol-3-yl)methanamines as potent and efficacious type II calcimimetics. J Med Chem (2009) 0.76