Published in J Am Soc Nephrol on April 25, 2007
Toll-like receptor 4 promotes tubular inflammation in diabetic nephropathy. J Am Soc Nephrol (2011) 1.72
The role of Toll-like receptors in renal diseases. Nat Rev Nephrol (2010) 1.42
Innate immune responses to systemic Acinetobacter baumannii infection in mice: neutrophils, but not interleukin-17, mediate host resistance. Infect Immun (2011) 1.14
Anti-GBM glomerulonephritis involves IL-1 but is independent of NLRP3/ASC inflammasome-mediated activation of caspase-1. PLoS One (2011) 1.08
TLR4 activation promotes podocyte injury and interstitial fibrosis in diabetic nephropathy. PLoS One (2014) 1.05
Fc gamma RIII and Fc gamma RIV are indispensable for acute glomerular inflammation induced by switch variant monoclonal antibodies. J Immunol (2008) 1.04
Toll-like receptor 4 expression is increased in circulating mononuclear cells of patients with immunoglobulin A nephropathy. Clin Exp Immunol (2009) 1.02
Leukocyte and serum S100A8/S100A9 expression reflects disease activity in ANCA-associated vasculitis and glomerulonephritis. Kidney Int (2013) 0.96
LPS and PAN-induced podocyte injury in an in vitro model of minimal change disease: changes in TLR profile. J Cell Commun Signal (2012) 0.96
Toll-like receptor 9 enhances nephritogenic immunity and glomerular leukocyte recruitment, exacerbating experimental crescentic glomerulonephritis. Am J Pathol (2010) 0.90
Toll-like receptor 4 stimulation triggers crescentic glomerulonephritis by multiple mechanisms including a direct effect on renal cells. Am J Pathol (2010) 0.88
Changes in the gene expression programs of renal mesangial cells during diabetic nephropathy. BMC Nephrol (2012) 0.87
Four danger response programs determine glomerular and tubulointerstitial kidney pathology: clotting, inflammation, epithelial and mesenchymal healing. Organogenesis (2012) 0.86
Toll-like receptor 4 signaling is involved in IgA-stimulated mesangial cell activation. Yonsei Med J (2011) 0.86
Neutrophil Extracellular Trap-Related Extracellular Histones Cause Vascular Necrosis in Severe GN. J Am Soc Nephrol (2015) 0.84
Sex Differences in monocytes and TLR4 associated immune responses; implications for systemic lupus erythematosus (SLE). J Immunother Appl (2014) 0.84
The role of innate immunity in donor organ procurement. Semin Immunopathol (2011) 0.83
Danger control programs cause tissue injury and remodeling. Int J Mol Sci (2013) 0.82
Toll-like receptor 3 signaling contributes to the expression of a neutrophil chemoattractant, CXCL1 in human mesangial cells. Clin Exp Nephrol (2014) 0.82
Resistin as a potential marker of renal disease in lupus nephritis. Clin Exp Immunol (2015) 0.81
Animal models of anti-neutrophil cytoplasmic antibody-associated vasculitis. Clin Exp Immunol (2012) 0.81
A two-hit mechanism for sepsis-induced impairment of renal tubule function. Am J Physiol Renal Physiol (2013) 0.81
How the Innate Immune System Senses Trouble and Causes Trouble. Clin J Am Soc Nephrol (2014) 0.80
Tissue kallikrein mediates pro-inflammatory pathways and activation of protease-activated receptor-4 in proximal tubular epithelial cells. PLoS One (2014) 0.80
Albumin stimulates renal tubular inflammation through an HSP70-TLR4 axis in mice with early diabetic nephropathy. Dis Model Mech (2015) 0.80
Renal effects of treatment with a TLR4 inhibitor in conscious septic sheep. Crit Care (2014) 0.79
Functional networks of aging markers in the glomeruli of IgA nephropathy: a new therapeutic opportunity. Oncotarget (2016) 0.77
Macrophage-mediated glucolipotoxicity via myeloid-related protein 8/toll-like receptor 4 signaling in diabetic nephropathy. Clin Exp Nephrol (2013) 0.77
Toll-like receptor 2 or toll-like receptor 4 deficiency does not modify lupus in MRLlpr mice. PLoS One (2013) 0.77
Differential expression of functional Fc-receptors and additional immune complex receptors on mouse kidney cells. Mol Immunol (2013) 0.77
Changes in the expression of the Toll-like receptor system in the aging rat kidneys. PLoS One (2014) 0.76
A20 regulates IL-1-induced tolerant production of CXC chemokines in human mesangial cells via inhibition of MAPK signaling. Sci Rep (2015) 0.75
Physiological aspects of Toll-like receptor 4 activation in sepsis-induced acute kidney injury. Acta Physiol (Oxf) (2016) 0.75
Pharmacological inhibition of macrophage toll-like receptor 4/nuclear factor-kappa B alleviates rhabdomyolysis-induced acute kidney injury. Chin Med J (Engl) (2017) 0.75
Screening of differentially expressed genes associated with Kawasaki disease by microarray analysis. Exp Ther Med (2017) 0.75
Trans-eQTLs reveal that independent genetic variants associated with a complex phenotype converge on intermediate genes, with a major role for the HLA. PLoS Genet (2011) 3.65
Local synthesis of complement component C3 regulates acute renal transplant rejection. Nat Med (2002) 3.39
Convergence and amplification of toll-like receptor (TLR) and receptor for advanced glycation end products (RAGE) signaling pathways via high mobility group B1 (HMGB1). Angiogenesis (2008) 2.89
In vivo expression of Toll-like receptor 2 and 4 by renal epithelial cells: IFN-gamma and TNF-alpha mediated up-regulation during inflammation. J Immunol (2002) 2.76
Myeloid type I interferon signaling promotes atherosclerosis by stimulating macrophage recruitment to lesions. Cell Metab (2010) 2.33
Local and systemic inflammation in patients with chronic obstructive pulmonary disease: soluble tumor necrosis factor receptors are increased in sputum. Am J Respir Crit Care Med (2002) 2.32
Unraveling the regulatory mechanisms underlying tissue-dependent genetic variation of gene expression. PLoS Genet (2012) 2.29
Disturbed intestinal integrity in patients with COPD: effects of activities of daily living. Chest (2014) 2.27
Influence of donor C3 allotype on late renal-transplantation outcome. N Engl J Med (2006) 1.97
Factor I is required for the development of membranoproliferative glomerulonephritis in factor H-deficient mice. J Clin Invest (2008) 1.94
Fc-dependent depletion of activated T cells occurs through CD40L-specific antibody rather than costimulation blockade. Nat Med (2003) 1.92
Non-alcoholic steatohepatitis: a non-invasive diagnosis by analysis of exhaled breath. J Hepatol (2012) 1.87
Toll-like receptor 2 agonists exacerbate accelerated nephrotoxic nephritis. J Am Soc Nephrol (2006) 1.87
C3a mediates epithelial-to-mesenchymal transition in proteinuric nephropathy. J Am Soc Nephrol (2009) 1.85
Pivotal role of CD4+ T cells in renal fibrosis following ureteric obstruction. Kidney Int (2010) 1.83
Nutritional stimulation of cholecystokinin receptors inhibits inflammation via the vagus nerve. J Exp Med (2005) 1.81
Kidneys from donors after cardiac death provide survival benefit. J Am Soc Nephrol (2010) 1.76
Complement factor C5a mediates renal ischemia-reperfusion injury independent from neutrophils. J Immunol (2003) 1.71
Long-term intratracheal lipopolysaccharide exposure in mice results in chronic lung inflammation and persistent pathology. Am J Respir Cell Mol Biol (2002) 1.71
Lack of evidence for the role of human adenovirus-36 in obesity in a European cohort. Obesity (Silver Spring) (2009) 1.70
Aggravation of anti-myeloperoxidase antibody-induced glomerulonephritis by bacterial lipopolysaccharide: role of tumor necrosis factor-alpha. Am J Pathol (2005) 1.65
Immunological and antitumor effects of IL-23 as a cancer vaccine adjuvant. J Immunol (2006) 1.59
Low molecular weight heparin attenuates multiple organ failure in a murine model of disseminated intravascular coagulation. Crit Care Med (2005) 1.58
Hyperglycemia in children with meningococcal sepsis and septic shock: the relation between plasma levels of insulin and inflammatory mediators. J Clin Endocrinol Metab (2006) 1.57
Dendritic cell synthesis of C3 is required for full T cell activation and development of a Th1 phenotype. J Immunol (2006) 1.57
Cholecystokinin/Cholecystokinin-1 receptor-mediated peripheral activation of the afferent vagus by enteral nutrients attenuates inflammation in rats. Ann Surg (2010) 1.51
Gut mucosal cell damage in meningococcal sepsis in children: relation with clinical outcome. Crit Care Med (2010) 1.49
Non-invasive markers for early diagnosis and determination of the severity of necrotizing enterocolitis. Ann Surg (2010) 1.49
Hemolysis is associated with acute kidney injury during major aortic surgery. Kidney Int (2010) 1.48
Arteriovenous fistula in the rat tail: a new model of hemodialysis access dysfunction. Kidney Int (2008) 1.48
Endogenous formation of Nε-(carboxymethyl)lysine is increased in fatty livers and induces inflammatory markers in an in vitro model of hepatic steatosis. J Hepatol (2011) 1.46
Aspiration pneumonitis primes the host for an exaggerated inflammatory response during pneumonia. Crit Care Med (2005) 1.46
Early insulin sensitivity after restrictive bariatric surgery, inconsistency between HOMA-IR and steady-state plasma glucose levels. Surg Obes Relat Dis (2009) 1.43
Collectin-11 detects stress-induced L-fucose pattern to trigger renal epithelial injury. J Clin Invest (2016) 1.43
Increased hepatic myeloperoxidase activity in obese subjects with nonalcoholic steatohepatitis. Am J Pathol (2009) 1.41
Prevention of hemolysis-induced organ damage by nutritional activation of the vagal anti-inflammatory reflex*. Crit Care Med (2013) 1.40
Six months of treatment with the endoscopic duodenal-jejunal bypass liner does not lead to decreased systemic inflammation in obese patients with type 2 diabetes. Obes Surg (2014) 1.40
Local extravascular pool of C3 is a determinant of postischemic acute renal failure. FASEB J (2006) 1.38
Local production and activation of complement up-regulates the allostimulatory function of dendritic cells through C3a-C3aR interaction. Blood (2007) 1.37
Apoptosis and inflammation in renal reperfusion injury. Transplantation (2002) 1.36
Cyclic AMP plays a critical role in C3a-receptor-mediated regulation of dendritic cells in antigen uptake and T-cell stimulation. Blood (2008) 1.33
Human intestinal microbiota composition is associated with local and systemic inflammation in obesity. Obesity (Silver Spring) (2013) 1.31
The mannose-binding lectin-pathway is involved in complement activation in the course of renal ischemia-reperfusion injury. Am J Pathol (2004) 1.28
Inhibition of complement factor C5 protects against renal ischemia-reperfusion injury: inhibition of late apoptosis and inflammation. Transplantation (2003) 1.27
Lipopolysaccharide (LPS)-binding protein mediates LPS detoxification by chylomicrons. J Immunol (2003) 1.26
Dendritic cell function in allostimulation is modulated by C5aR signaling. J Immunol (2009) 1.24
Myeloperoxidase is critically involved in the induction of organ damage after renal ischemia reperfusion. Am J Pathol (2007) 1.24
Early diagnosis of intestinal ischemia using urinary and plasma fatty acid binding proteins. Ann Surg (2011) 1.22
The role of anaphylatoxins C3a and C5a in regulating innate and adaptive immune responses. Inflamm Allergy Drug Targets (2009) 1.22
De novo lipogenesis in human fat and liver is linked to ChREBP-β and metabolic health. Nat Commun (2013) 1.20
Cardiovascular surgery and organ damage: time to reconsider the role of hemolysis. J Thorac Cardiovasc Surg (2011) 1.20
Liver manipulation causes hepatocyte injury and precedes systemic inflammation in patients undergoing liver resection. World J Surg (2007) 1.20
Macrophages from C3-deficient mice have impaired potency to stimulate alloreactive T cells. Blood (2005) 1.19
A pilot study on the noninvasive evaluation of intestinal damage in celiac disease using I-FABP and L-FABP. J Clin Gastroenterol (2009) 1.18
Endotoxin induced chorioamnionitis prevents intestinal development during gestation in fetal sheep. PLoS One (2009) 1.17
Homeostatic proliferation of lymphocytes results in augmented memory-like function and accelerated allograft rejection. J Immunol (2008) 1.17
Non-invasive assessment of barrier integrity and function of the human gut. World J Gastrointest Surg (2010) 1.16
Neutrophil activation in morbid obesity, chronic activation of acute inflammation. Obesity (Silver Spring) (2009) 1.16
Human intestinal ischemia-reperfusion-induced inflammation characterized: experiences from a new translational model. Am J Pathol (2010) 1.16
Activation of the complement system in human nonalcoholic fatty liver disease. Hepatology (2009) 1.16
Blood transfusions increase circulating plasma free hemoglobin levels and plasma nitric oxide consumption: a prospective observational pilot study. Crit Care (2012) 1.16
Evidence for intestinal and liver epithelial cell injury in the early phase of sepsis. Shock (2007) 1.15
Short chain fatty acids exchange across the gut and liver in humans measured at surgery. Clin Nutr (2009) 1.14
Pretreatment with high-fat enteral nutrition reduces endotoxin and tumor necrosis factor-alpha and preserves gut barrier function early after hemorrhagic shock. Shock (2004) 1.13
Specific immunization strategies against oxidized low-density lipoprotein: a novel way to reduce nonalcoholic steatohepatitis in mice. Hepatology (2012) 1.13
Circulating intestinal fatty acid-binding protein as an early marker of intestinal necrosis after aortic surgery: a prospective observational cohort study. Ann Surg (2012) 1.13
TLR2 stimulation of intrinsic renal cells in the induction of immune-mediated glomerulonephritis. J Immunol (2006) 1.12
Localization of the lipopolysaccharide recognition complex in the human healthy and inflamed premature and adult gut. Inflamm Bowel Dis (2010) 1.11
Synthesis of complement protein C3 in the kidney is an important mediator of local tissue injury. FASEB J (2007) 1.11
Challenges in diagnosing mesenteric ischemia. World J Gastroenterol (2013) 1.11
Strain-specific effects of probiotics on gut barrier integrity following hemorrhagic shock. Infect Immun (2005) 1.10
Kidney transplantation from donors after cardiac death: a 25-year experience. Transplantation (2010) 1.10
Exercise-induced splanchnic hypoperfusion results in gut dysfunction in healthy men. PLoS One (2011) 1.10
Defective Fc-dependent processing of immune complexes in patients with systemic lupus erythematosus. Arthritis Rheum (2002) 1.10
Genetic and epigenetic regulation of gene expression in fetal and adult human livers. BMC Genomics (2014) 1.09
Evaluation of the diagnostic accuracy of plasma markers for early diagnosis in patients suspected for acute appendicitis. Acad Emerg Med (2013) 1.08
Inhibition of TLR2 promotes graft function in a murine model of renal transplant ischemia-reperfusion injury. FASEB J (2011) 1.08
Therapeutic strategy with a membrane-localizing complement regulator to increase the number of usable donor organs after prolonged cold storage. J Am Soc Nephrol (2006) 1.08
Rapid reversal of human intestinal ischemia-reperfusion induced damage by shedding of injured enterocytes and reepithelialisation. PLoS One (2008) 1.08
Lipid-rich enteral nutrition reduces postoperative ileus in rats via activation of cholecystokinin-receptors. Ann Surg (2009) 1.08
Nephrotoxic nephritis is mediated by Fcgamma receptors on circulating leukocytes and not intrinsic renal cells. Kidney Int (2002) 1.07
Intestinal-FABP and liver-FABP: Novel markers for severe abdominal injury. Acad Emerg Med (2010) 1.07
Chorioamnionitis as a risk factor for necrotizing enterocolitis: a systematic review and meta-analysis. J Pediatr (2012) 1.07
Level of activation of the unfolded protein response correlates with Paneth cell apoptosis in human small intestine exposed to ischemia/reperfusion. Gastroenterology (2010) 1.07
Intestinal cytoskeleton degradation precedes tight junction loss following hemorrhagic shock. Shock (2009) 1.07
Common genetic variants in complement genes other than CFH, CD46 and the CFHRs are not associated with aHUS. Mol Immunol (2011) 1.06
Citrulline a more suitable substrate than arginine to restore NO production and the microcirculation during endotoxemia. PLoS One (2012) 1.06
Noninvasive measurement of fecal calprotectin and serum amyloid A combined with intestinal fatty acid-binding protein in necrotizing enterocolitis. J Pediatr Surg (2012) 1.06
Deficiency of C4 from donor or recipient mouse fails to prevent renal allograft rejection. Am J Pathol (2006) 1.06
Reduction of circulating redox-active iron by apotransferrin protects against renal ischemia-reperfusion injury. Transplantation (2004) 1.05
Intestinal permeability and carrier-mediated monosaccharide absorption in preterm neonates during the early postnatal period. Pediatr Res (2002) 1.05
Endoscopic duodenal-jejunal bypass liner rapidly improves type 2 diabetes. Obes Surg (2013) 1.05