Published in Nat Med on June 01, 2002
The role of the anaphylatoxins in health and disease. Mol Immunol (2009) 2.95
Decay-accelerating factor modulates induction of T cell immunity. J Exp Med (2005) 2.34
The complement inhibitory protein DAF (CD55) suppresses T cell immunity in vivo. J Exp Med (2005) 2.09
Delayed graft function in the kidney transplant. Am J Transplant (2011) 2.06
Complement 5a receptor inhibition improves renal allograft survival. J Am Soc Nephrol (2008) 1.72
Decay accelerating factor can control T cell differentiation into IFN-gamma-producing effector cells via regulating local C5a-induced IL-12 production. J Immunol (2007) 1.59
Altered renal tubular expression of the complement inhibitor Crry permits complement activation after ischemia/reperfusion. J Clin Invest (2006) 1.57
Oxidative stress renders retinal pigment epithelial cells susceptible to complement-mediated injury. J Biol Chem (2009) 1.45
Collectin-11 detects stress-induced L-fucose pattern to trigger renal epithelial injury. J Clin Invest (2016) 1.43
The role of Toll-like receptors in renal diseases. Nat Rev Nephrol (2010) 1.42
Complement Factor B Production in Renal Tubular Cells and Its Role in Sodium Transporter Expression During Polymicrobial Sepsis. Crit Care Med (2016) 1.39
New insights into postrenal transplant hemolytic uremic syndrome. Nat Rev Nephrol (2010) 1.36
Complement--tapping into new sites and effector systems. Nat Rev Immunol (2014) 1.30
Donor deficiency of decay-accelerating factor accelerates murine T cell-mediated cardiac allograft rejection. J Immunol (2008) 1.28
The role of complement in the early immune response to transplantation. Nat Rev Immunol (2012) 1.26
Complement independent antibody-mediated endarteritis and transplant arteriopathy in mice. Am J Transplant (2010) 1.23
Autocrine effects of tumor-derived complement. Cell Rep (2014) 1.16
Expression of complement components differs between kidney allografts from living and deceased donors. J Am Soc Nephrol (2009) 1.16
Gene expression profiling in acute allograft rejection: challenging the immunologic constant of rejection hypothesis. J Transl Med (2011) 1.15
Proteomic signatures in plasma during early acute renal allograft rejection. Mol Cell Proteomics (2010) 1.14
Molecular mechanisms of chronic kidney transplant rejection via large-scale proteogenomic analysis of tissue biopsies. J Am Soc Nephrol (2010) 1.13
Dissecting the instant blood-mediated inflammatory reaction in islet xenotransplantation. Xenotransplantation (2008) 1.12
Kinetics of gene expression in murine cutaneous graft-versus-host disease. Am J Pathol (2004) 1.08
Deficiency of C4 from donor or recipient mouse fails to prevent renal allograft rejection. Am J Pathol (2006) 1.06
Myasthenia gravis thymus: complement vulnerability of epithelial and myoid cells, complement attack on them, and correlations with autoantibody status. Am J Pathol (2007) 1.05
Complement-mediated dysfunction of glomerular filtration barrier accelerates progressive renal injury. J Am Soc Nephrol (2008) 1.04
Mechanisms of complement activation, C4d deposition, and their contribution to the pathogenesis of antibody-mediated rejection. Transplant Rev (Orlando) (2009) 1.03
New concepts of complement in allorecognition and graft rejection. Cell Immunol (2007) 1.02
Alloantibody and complement promote T cell-mediated cardiac allograft vasculopathy through noncanonical nuclear factor-κB signaling in endothelial cells. Circulation (2013) 1.00
Acute antibody-mediated complement activation mediates lysis of pancreatic islets cells and may cause tissue loss in clinical islet transplantation. Transplantation (2008) 1.00
Mice lacking C1q or C3 show accelerated rejection of minor H disparate skin grafts and resistance to induction of tolerance. Eur J Immunol (2010) 0.99
A missense mutation in factor I (IF) predisposes to atypical haemolytic uraemic syndrome. Pediatr Nephrol (2006) 0.99
Immune cell-derived C3a and C5a costimulate human T cell alloimmunity. Am J Transplant (2013) 0.98
Nontransgenic hyperexpression of a complement regulator in donor kidney modulates transplant ischemia/reperfusion damage, acute rejection, and chronic nephropathy. Am J Pathol (2003) 0.97
Role and mechanism of action of complement in regulating T cell immunity. Mol Immunol (2010) 0.97
Complement in disease: a defence system turning offensive. Nat Rev Nephrol (2016) 0.97
Recent progress and new perspectives in studying T cell responses to allografts. Am J Transplant (2010) 0.96
Complement and its role in protection and pathogenesis of flavivirus infections. Vaccine (2008) 0.96
Complement regulation of T cell immunity. Immunol Res (2012) 0.95
The complement inhibitors Crry and factor H are critical for preventing autologous complement activation on renal tubular epithelial cells. J Immunol (2010) 0.95
C3 promotes expansion of CD8+ and CD4+ T cells in a Listeria monocytogenes infection. J Immunol (2009) 0.95
Complement gene expression in human cardiac allograft biopsies as a correlate of histologic grade of injury. Transplantation (2008) 0.93
Autoantibody-mediated complement C3a receptor activation contributes to the pathogenesis of preeclampsia. Hypertension (2012) 0.92
The immunomodulatory role of carbon monoxide during transplantation. Med Gas Res (2013) 0.92
Renal ischemia-reperfusion injury amplifies the humoral immune response. J Am Soc Nephrol (2013) 0.91
Molecules Great and Small: The Complement System. Clin J Am Soc Nephrol (2015) 0.91
Update on ischemia-reperfusion injury in kidney transplantation: Pathogenesis and treatment. World J Transplant (2015) 0.90
The complement cascade and renal disease. Arch Immunol Ther Exp (Warsz) (2013) 0.90
Complement receptors and the shaping of the natural antibody repertoire. Springer Semin Immunopathol (2004) 0.90
Complement as a multifaceted modulator of kidney transplant injury. J Clin Invest (2014) 0.89
Mechanisms involved in antibody- and complement-mediated allograft rejection. Immunol Res (2010) 0.88
Decay accelerating factor is essential for successful corneal engraftment. Am J Transplant (2010) 0.87
Genotypic diversity of complement component C4 does not predict kidney transplant outcome. J Am Soc Nephrol (2010) 0.86
Evolving paradigms that determine the fate of an allograft. Am J Transplant (2010) 0.86
The role of complement in the pathogenesis of renal ischemia-reperfusion injury and fibrosis. Fibrogenesis Tissue Repair (2014) 0.86
Clinical analysis of perioperative complement activity during ischemia/reperfusion injury following renal transplantation. Clin J Am Soc Nephrol (2012) 0.86
The major histocompatibility complex in transplantation. J Transplant (2012) 0.86
Innate immunity and resistance to tolerogenesis in allotransplantation. Front Immunol (2012) 0.85
Allograft outcomes in outbred mice. Am J Transplant (2013) 0.85
Allograft rejection: effect of local synthesis of complement. Springer Semin Immunopathol (2005) 0.85
Kidney injury accelerates cystogenesis via pathways modulated by heme oxygenase and complement. J Am Soc Nephrol (2012) 0.84
Plasma complement levels are associated with primary graft dysfunction and mortality after lung transplantation. Am J Respir Crit Care Med (2014) 0.84
The complement system at the embryo implantation site: friend or foe? Front Immunol (2012) 0.84
The innate immune system in transplantation. Semin Immunol (2011) 0.84
The "ins and outs" of complement-driven immune responses. Immunol Rev (2016) 0.84
Tissue-specific exosome biomarkers for noninvasively monitoring immunologic rejection of transplanted tissue. J Clin Invest (2017) 0.83
The role of the complement system in acute kidney injury. Semin Nephrol (2013) 0.83
Memory T cells in organ transplantation: progress and challenges. Nat Rev Nephrol (2016) 0.83
Which pathways trigger the role of complement in ischaemia/reperfusion injury? Front Immunol (2012) 0.83
Recombinant complement receptor 2 radiolabeled with [99mTc(CO)3]+: a potential new radiopharmaceutical for imaging activated complement. PLoS One (2011) 0.83
CD28 family and chronic rejection: "to belatacept...And beyond!". J Transplant (2012) 0.82
Gene expression profiling of the donor kidney at the time of transplantation predicts clinical outcomes 2 years after transplantation. Hum Immunol (2010) 0.82
Immune-mediated vascular injury and dysfunction in transplant arteriosclerosis. Front Immunol (2015) 0.82
A glow of HLA typing in organ transplantation. Clin Transl Med (2013) 0.81
Reduced graft-versus-host disease in C3-deficient mice is associated with decreased donor Th1/Th17 differentiation. Biol Blood Marrow Transplant (2012) 0.81
Complement regulation of T-cell alloimmunity. Semin Nephrol (2013) 0.81
Enhancing complement control on endothelial barrier reduces renal post-ischemia dysfunction. J Surg Res (2011) 0.81
Complement and HIV-I infection/HIV-associated neurocognitive disorders. J Neurovirol (2014) 0.80
Complement Component 3 Is Regulated by TWIST1 and Mediates Epithelial-Mesenchymal Transition. J Immunol (2015) 0.80
Location, location, location: regional immune mechanisms critically influence rejection. Nat Med (2002) 0.80
The role of renin angiotensin system inhibition in kidney repair. Fibrogenesis Tissue Repair (2010) 0.80
Complement involvement in kidney diseases: From physiopathology to therapeutical targeting. World J Nephrol (2015) 0.80
An anticomplement agent that homes to the damaged brain and promotes recovery after traumatic brain injury in mice. Proc Natl Acad Sci U S A (2015) 0.79
Effects of complement activation on allograft injury. Curr Opin Organ Transplant (2015) 0.79
Complement component C3 mediates Th1/Th17 polarization in human T-cell activation and cutaneous GVHD. Bone Marrow Transplant (2014) 0.79
The innate immune system and transplantation. Cold Spring Harb Perspect Med (2013) 0.79
Activation of intrarenal complement system in mouse model for chronic cyclosporine nephrotoxicity. Yonsei Med J (2007) 0.78
Lessons and limits of mouse models. Cold Spring Harb Perspect Med (2013) 0.78
Deletion of putative intronic control sequences does not alter cell or stage specific expression of Cr2. Mol Immunol (2009) 0.78
Noninvasive diagnosis of acute cellular rejection in liver transplant recipients: a proteomic signature validated by enzyme-linked immunosorbent assay. Liver Transpl (2011) 0.78
Complement regulation of T-cell alloimmunity. Curr Opin Organ Transplant (2011) 0.78
Capillary deposition of complement C4d and C3d in Chinese renal allograft biopsies. Dis Markers (2015) 0.77
Complement activation in progressive renal disease. World J Nephrol (2015) 0.77
Atypical hemolytic uremic syndrome post-kidney transplantation: two case reports and review of the literature. Front Med (Lausanne) (2014) 0.77
Cardiomyopathy is linked to complement activation. Am J Pathol (2002) 0.77
Innate immunity in donor procurement. Curr Opin Organ Transplant (2013) 0.77
Shift of C3 deposition from localization in the glomerulus into the tubulo-interstitial compartment in the absence of secreted IgM in immune complex glomerulonephritis. Clin Exp Immunol (2007) 0.77
Amelioration of renal damage by administration of anti-thymocyte globulin to potential donors in a brain death rat model. Clin Exp Immunol (2012) 0.76
Noninvasive Imaging of Activated Complement in Ischemia-Reperfusion Injury Post-Cardiac Transplant. Am J Transplant (2015) 0.76
Transplant rejection: mind your T-cell language. Nat Med (2002) 0.76
Influence of donor C3 allotype on late renal-transplantation outcome. N Engl J Med (2006) 1.97
Factor I is required for the development of membranoproliferative glomerulonephritis in factor H-deficient mice. J Clin Invest (2008) 1.94
Fc-dependent depletion of activated T cells occurs through CD40L-specific antibody rather than costimulation blockade. Nat Med (2003) 1.92
Toll-like receptor 2 agonists exacerbate accelerated nephrotoxic nephritis. J Am Soc Nephrol (2006) 1.87
C3a mediates epithelial-to-mesenchymal transition in proteinuric nephropathy. J Am Soc Nephrol (2009) 1.85
Pivotal role of CD4+ T cells in renal fibrosis following ureteric obstruction. Kidney Int (2010) 1.83
Dendritic cell synthesis of C3 is required for full T cell activation and development of a Th1 phenotype. J Immunol (2006) 1.57
Collectin-11 detects stress-induced L-fucose pattern to trigger renal epithelial injury. J Clin Invest (2016) 1.43
Local extravascular pool of C3 is a determinant of postischemic acute renal failure. FASEB J (2006) 1.38
Local production and activation of complement up-regulates the allostimulatory function of dendritic cells through C3a-C3aR interaction. Blood (2007) 1.37
Cyclic AMP plays a critical role in C3a-receptor-mediated regulation of dendritic cells in antigen uptake and T-cell stimulation. Blood (2008) 1.33
Toll-like receptor 4 ligation on intrinsic renal cells contributes to the induction of antibody-mediated glomerulonephritis via CXCL1 and CXCL2. J Am Soc Nephrol (2007) 1.27
Dendritic cell function in allostimulation is modulated by C5aR signaling. J Immunol (2009) 1.24
The role of anaphylatoxins C3a and C5a in regulating innate and adaptive immune responses. Inflamm Allergy Drug Targets (2009) 1.22
Macrophages from C3-deficient mice have impaired potency to stimulate alloreactive T cells. Blood (2005) 1.19
Homeostatic proliferation of lymphocytes results in augmented memory-like function and accelerated allograft rejection. J Immunol (2008) 1.17
TLR2 stimulation of intrinsic renal cells in the induction of immune-mediated glomerulonephritis. J Immunol (2006) 1.12
Synthesis of complement protein C3 in the kidney is an important mediator of local tissue injury. FASEB J (2007) 1.11
Inhibition of TLR2 promotes graft function in a murine model of renal transplant ischemia-reperfusion injury. FASEB J (2011) 1.08
Therapeutic strategy with a membrane-localizing complement regulator to increase the number of usable donor organs after prolonged cold storage. J Am Soc Nephrol (2006) 1.08
Common genetic variants in complement genes other than CFH, CD46 and the CFHRs are not associated with aHUS. Mol Immunol (2011) 1.06
Deficiency of C4 from donor or recipient mouse fails to prevent renal allograft rejection. Am J Pathol (2006) 1.06
C3a and C5a promote renal ischemia-reperfusion injury. J Am Soc Nephrol (2012) 1.05
Fc gamma RIII and Fc gamma RIV are indispensable for acute glomerular inflammation induced by switch variant monoclonal antibodies. J Immunol (2008) 1.04
Mechanisms of disease: the complement system in renal injury--new ways of looking at an old foe. Nat Clin Pract Nephrol (2007) 1.03
The use of eculizumab in renal transplantation. Clin Transplant (2013) 1.00
The relative importance of local and systemic complement production in ischaemia, transplantation and other pathologies. Mol Immunol (2007) 1.00
CD59a deficiency exacerbates ischemia-reperfusion injury in mice. Am J Pathol (2004) 0.98
Nontransgenic hyperexpression of a complement regulator in donor kidney modulates transplant ischemia/reperfusion damage, acute rejection, and chronic nephropathy. Am J Pathol (2003) 0.97
Functional modulation of human monocytes derived DCs by anaphylatoxins C3a and C5a. Immunobiology (2011) 0.97
Expression of complement components, receptors and regulators by human dendritic cells. Mol Immunol (2011) 0.96
CD46 (membrane cofactor protein) acts as a human epithelial cell receptor for internalization of opsonized uropathogenic Escherichia coli. J Immunol (2006) 0.95
Controlling the generation and function of human CD8+ memory T cells in vitro with immunosuppressants. Transplantation (2006) 0.94
Complement activation regulates the capacity of proximal tubular epithelial cell to stimulate alloreactive T cell response. J Am Soc Nephrol (2004) 0.94
Minireview: functions of the renal tract epithelium in coordinating the innate immune response to infection. Kidney Int (2004) 0.92
Ultra-localization of Foxp3+ T cells within renal allografts shows infiltration of tubules mimicking rejection. Am J Pathol (2007) 0.92
Natural killer-cell activity after human renal transplantation in relation to killer immunoglobulin-like receptors and human leukocyte antigen mismatch. Transplantation (2003) 0.92
Extensive and bidirectional transfer of major histocompatibility complex class II molecules between donor and recipient cells in vivo following solid organ transplantation. FASEB J (2008) 0.91
Synergy between type 1 fimbriae expression and C3 opsonisation increases internalisation of E. coli by human tubular epithelial cells. BMC Microbiol (2009) 0.91
The classical complement pathway plays a critical role in the opsonisation of uropathogenic Escherichia coli. Mol Immunol (2007) 0.90
Role of dendritic cell synthesis of complement in the allospecific T cell response. Mol Immunol (2006) 0.90
Independent pathways of P-selectin and complement-mediated renal ischemia/reperfusion injury. Am J Pathol (2004) 0.89
Toll-like receptor 4 stimulation triggers crescentic glomerulonephritis by multiple mechanisms including a direct effect on renal cells. Am J Pathol (2010) 0.88
Deficiency of C5aR prolongs renal allograft survival. J Am Soc Nephrol (2010) 0.88
Rapamycin at subimmunosuppressive levels inhibits mesangial cell proliferation and extracellular matrix production. Am J Physiol Renal Physiol (2006) 0.88
Tertiary lymphoid organs in renal allografts can be associated with donor-specific tolerance rather than rejection. Eur J Immunol (2010) 0.87
Mechanisms of rejection: role of complement. Curr Opin Organ Transplant (2014) 0.86
Which pathways trigger the role of complement in ischaemia/reperfusion injury? Front Immunol (2012) 0.83
RNA interference--a new experimental and therapeutic tool. Curr Opin Nephrol Hypertens (2005) 0.79
Triptolide is a potent suppressant of C3, CD40 and B7h expression in activated human proximal tubular epithelial cells. Kidney Int (2002) 0.79
The innate immune system and transplantation. Cold Spring Harb Perspect Med (2013) 0.79
Role of complement in tubulointerstitial injury from proteinuria. Kidney Blood Press Res (2002) 0.78
Accumulation of immune complexes in glomerular disease is independent of locally synthesized c3. J Am Soc Nephrol (2006) 0.77
C1 esterase inhibitor reduces lower extremity ischemia/reperfusion injury and associated lung damage. PLoS One (2013) 0.77
Control of innate immunological mechanisms as a route to drug minimization. Curr Opin Organ Transplant (2014) 0.77
The role of complement and Toll-like receptors in organ transplantation. Transpl Int (2007) 0.77
Donor specific transplant tolerance is dependent on complement receptors. Transpl Int (2012) 0.76
Footprints of humoral rejection. Curr Opin Nephrol Hypertens (2002) 0.75