PubRank

Steven H Sacks

Author PubWeight™ 65.28‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Local synthesis of complement component C3 regulates acute renal transplant rejection. Nat Med 2002 3.39
2 Influence of donor C3 allotype on late renal-transplantation outcome. N Engl J Med 2006 1.97
3 Factor I is required for the development of membranoproliferative glomerulonephritis in factor H-deficient mice. J Clin Invest 2008 1.94
4 Fc-dependent depletion of activated T cells occurs through CD40L-specific antibody rather than costimulation blockade. Nat Med 2003 1.92
5 Toll-like receptor 2 agonists exacerbate accelerated nephrotoxic nephritis. J Am Soc Nephrol 2006 1.87
6 C3a mediates epithelial-to-mesenchymal transition in proteinuric nephropathy. J Am Soc Nephrol 2009 1.85
7 Pivotal role of CD4+ T cells in renal fibrosis following ureteric obstruction. Kidney Int 2010 1.83
8 Dendritic cell synthesis of C3 is required for full T cell activation and development of a Th1 phenotype. J Immunol 2006 1.57
9 Collectin-11 detects stress-induced L-fucose pattern to trigger renal epithelial injury. J Clin Invest 2016 1.43
10 Local extravascular pool of C3 is a determinant of postischemic acute renal failure. FASEB J 2006 1.38
11 Local production and activation of complement up-regulates the allostimulatory function of dendritic cells through C3a-C3aR interaction. Blood 2007 1.37
12 Cyclic AMP plays a critical role in C3a-receptor-mediated regulation of dendritic cells in antigen uptake and T-cell stimulation. Blood 2008 1.33
13 Toll-like receptor 4 ligation on intrinsic renal cells contributes to the induction of antibody-mediated glomerulonephritis via CXCL1 and CXCL2. J Am Soc Nephrol 2007 1.27
14 Dendritic cell function in allostimulation is modulated by C5aR signaling. J Immunol 2009 1.24
15 The role of anaphylatoxins C3a and C5a in regulating innate and adaptive immune responses. Inflamm Allergy Drug Targets 2009 1.22
16 Macrophages from C3-deficient mice have impaired potency to stimulate alloreactive T cells. Blood 2005 1.19
17 Homeostatic proliferation of lymphocytes results in augmented memory-like function and accelerated allograft rejection. J Immunol 2008 1.17
18 TLR2 stimulation of intrinsic renal cells in the induction of immune-mediated glomerulonephritis. J Immunol 2006 1.12
19 Synthesis of complement protein C3 in the kidney is an important mediator of local tissue injury. FASEB J 2007 1.11
20 Inhibition of TLR2 promotes graft function in a murine model of renal transplant ischemia-reperfusion injury. FASEB J 2011 1.08
21 Therapeutic strategy with a membrane-localizing complement regulator to increase the number of usable donor organs after prolonged cold storage. J Am Soc Nephrol 2006 1.08
22 Common genetic variants in complement genes other than CFH, CD46 and the CFHRs are not associated with aHUS. Mol Immunol 2011 1.06
23 Deficiency of C4 from donor or recipient mouse fails to prevent renal allograft rejection. Am J Pathol 2006 1.06
24 C3a and C5a promote renal ischemia-reperfusion injury. J Am Soc Nephrol 2012 1.05
25 Fc gamma RIII and Fc gamma RIV are indispensable for acute glomerular inflammation induced by switch variant monoclonal antibodies. J Immunol 2008 1.04
26 Mechanisms of disease: the complement system in renal injury--new ways of looking at an old foe. Nat Clin Pract Nephrol 2007 1.03
27 The use of eculizumab in renal transplantation. Clin Transplant 2013 1.00
28 The relative importance of local and systemic complement production in ischaemia, transplantation and other pathologies. Mol Immunol 2007 1.00
29 CD59a deficiency exacerbates ischemia-reperfusion injury in mice. Am J Pathol 2004 0.98
30 Nontransgenic hyperexpression of a complement regulator in donor kidney modulates transplant ischemia/reperfusion damage, acute rejection, and chronic nephropathy. Am J Pathol 2003 0.97
31 Functional modulation of human monocytes derived DCs by anaphylatoxins C3a and C5a. Immunobiology 2011 0.97
32 Expression of complement components, receptors and regulators by human dendritic cells. Mol Immunol 2011 0.96
33 CD46 (membrane cofactor protein) acts as a human epithelial cell receptor for internalization of opsonized uropathogenic Escherichia coli. J Immunol 2006 0.95
34 Controlling the generation and function of human CD8+ memory T cells in vitro with immunosuppressants. Transplantation 2006 0.94
35 Complement activation regulates the capacity of proximal tubular epithelial cell to stimulate alloreactive T cell response. J Am Soc Nephrol 2004 0.94
36 Minireview: functions of the renal tract epithelium in coordinating the innate immune response to infection. Kidney Int 2004 0.92
37 Ultra-localization of Foxp3+ T cells within renal allografts shows infiltration of tubules mimicking rejection. Am J Pathol 2007 0.92
38 Natural killer-cell activity after human renal transplantation in relation to killer immunoglobulin-like receptors and human leukocyte antigen mismatch. Transplantation 2003 0.92
39 Extensive and bidirectional transfer of major histocompatibility complex class II molecules between donor and recipient cells in vivo following solid organ transplantation. FASEB J 2008 0.91
40 Synergy between type 1 fimbriae expression and C3 opsonisation increases internalisation of E. coli by human tubular epithelial cells. BMC Microbiol 2009 0.91
41 Role of dendritic cell synthesis of complement in the allospecific T cell response. Mol Immunol 2006 0.90
42 The classical complement pathway plays a critical role in the opsonisation of uropathogenic Escherichia coli. Mol Immunol 2007 0.90
43 Independent pathways of P-selectin and complement-mediated renal ischemia/reperfusion injury. Am J Pathol 2004 0.89
44 Deficiency of C5aR prolongs renal allograft survival. J Am Soc Nephrol 2010 0.88
45 Rapamycin at subimmunosuppressive levels inhibits mesangial cell proliferation and extracellular matrix production. Am J Physiol Renal Physiol 2006 0.88
46 Toll-like receptor 4 stimulation triggers crescentic glomerulonephritis by multiple mechanisms including a direct effect on renal cells. Am J Pathol 2010 0.88
47 Tertiary lymphoid organs in renal allografts can be associated with donor-specific tolerance rather than rejection. Eur J Immunol 2010 0.87
48 Mechanisms of rejection: role of complement. Curr Opin Organ Transplant 2014 0.86
49 Which pathways trigger the role of complement in ischaemia/reperfusion injury? Front Immunol 2012 0.83
50 Triptolide is a potent suppressant of C3, CD40 and B7h expression in activated human proximal tubular epithelial cells. Kidney Int 2002 0.79
51 RNA interference--a new experimental and therapeutic tool. Curr Opin Nephrol Hypertens 2005 0.79
52 The innate immune system and transplantation. Cold Spring Harb Perspect Med 2013 0.79
53 Role of complement in tubulointerstitial injury from proteinuria. Kidney Blood Press Res 2002 0.78
54 Accumulation of immune complexes in glomerular disease is independent of locally synthesized c3. J Am Soc Nephrol 2006 0.77
55 C1 esterase inhibitor reduces lower extremity ischemia/reperfusion injury and associated lung damage. PLoS One 2013 0.77
56 The role of complement and Toll-like receptors in organ transplantation. Transpl Int 2007 0.77
57 Control of innate immunological mechanisms as a route to drug minimization. Curr Opin Organ Transplant 2014 0.77
58 Donor specific transplant tolerance is dependent on complement receptors. Transpl Int 2012 0.76
59 Footprints of humoral rejection. Curr Opin Nephrol Hypertens 2002 0.75