Published in J Immunol on March 15, 2006
Locally produced complement fragments C5a and C3a provide both costimulatory and survival signals to naive CD4+ T cells. Immunity (2008) 3.36
The role of the anaphylatoxins in health and disease. Mol Immunol (2009) 2.95
Decay accelerating factor can control T cell differentiation into IFN-gamma-producing effector cells via regulating local C5a-induced IL-12 production. J Immunol (2007) 1.59
Signaling through C5a receptor and C3a receptor diminishes function of murine natural regulatory T cells. J Exp Med (2013) 1.48
Complement System Part II: Role in Immunity. Front Immunol (2015) 1.31
Application of pharmacogenomics to vaccines. Pharmacogenomics (2009) 1.30
Donor deficiency of decay-accelerating factor accelerates murine T cell-mediated cardiac allograft rejection. J Immunol (2008) 1.28
The role of complement in the early immune response to transplantation. Nat Rev Immunol (2012) 1.26
Mechanisms of maladaptive repair after AKI leading to accelerated kidney ageing and CKD. Nat Rev Nephrol (2015) 1.24
Gene expression profiling in acute allograft rejection: challenging the immunologic constant of rejection hypothesis. J Transl Med (2011) 1.15
Dissecting the instant blood-mediated inflammatory reaction in islet xenotransplantation. Xenotransplantation (2008) 1.12
Systemic and local anti-C5 therapy reduces the disease severity in experimental autoimmune uveoretinitis. Clin Exp Immunol (2009) 1.09
Antigen-presenting cell-derived complement modulates graft-versus-host disease. J Clin Invest (2012) 1.09
Nucleic acids and endosomal pattern recognition: how to tell friend from foe? Front Cell Infect Microbiol (2013) 1.04
Mechanisms of complement activation, C4d deposition, and their contribution to the pathogenesis of antibody-mediated rejection. Transplant Rev (Orlando) (2009) 1.03
New concepts of complement in allorecognition and graft rejection. Cell Immunol (2007) 1.02
Acute antibody-mediated complement activation mediates lysis of pancreatic islets cells and may cause tissue loss in clinical islet transplantation. Transplantation (2008) 1.00
Mice lacking C1q or C3 show accelerated rejection of minor H disparate skin grafts and resistance to induction of tolerance. Eur J Immunol (2010) 0.99
Opposing roles for complement component C5a in tumor progression and the tumor microenvironment. J Immunol (2012) 0.98
Role and mechanism of action of complement in regulating T cell immunity. Mol Immunol (2010) 0.97
Expression of complement components, receptors and regulators by human dendritic cells. Mol Immunol (2011) 0.96
C3 promotes expansion of CD8+ and CD4+ T cells in a Listeria monocytogenes infection. J Immunol (2009) 0.95
Complement gene expression in human cardiac allograft biopsies as a correlate of histologic grade of injury. Transplantation (2008) 0.93
The role of complement component 3 (C3) in differentiation of myeloid-derived suppressor cells. Blood (2013) 0.92
From secretome analysis to immunology: chitosan induces major alterations in the activation of dendritic cells via a TLR4-dependent mechanism. Mol Cell Proteomics (2009) 0.91
The complement cascade and renal disease. Arch Immunol Ther Exp (Warsz) (2013) 0.90
Anti-complement component C5 mAb synergizes with CTLA4Ig to inhibit alloreactive T cells and prolong cardiac allograft survival in mice. Am J Transplant (2011) 0.90
C3 opsonization regulates endocytic handling of apoptotic cells resulting in enhanced T-cell responses to cargo-derived antigens. Proc Natl Acad Sci U S A (2014) 0.89
Role of complement in protection against Cryptococcus gattii infection. Infect Immun (2008) 0.87
Clinical analysis of perioperative complement activity during ischemia/reperfusion injury following renal transplantation. Clin J Am Soc Nephrol (2012) 0.86
Innate immunity and resistance to tolerogenesis in allotransplantation. Front Immunol (2012) 0.85
Innate and adaptive immunologic functions of complement in the host response to Listeria monocytogenes infection. Immunobiology (2016) 0.82
Reduced graft-versus-host disease in C3-deficient mice is associated with decreased donor Th1/Th17 differentiation. Biol Blood Marrow Transplant (2012) 0.81
Complement involvement in kidney diseases: From physiopathology to therapeutical targeting. World J Nephrol (2015) 0.80
Complement component C3 mediates Th1/Th17 polarization in human T-cell activation and cutaneous GVHD. Bone Marrow Transplant (2014) 0.79
The innate immune system and transplantation. Cold Spring Harb Perspect Med (2013) 0.79
Renal C3 complement component: feed forward to diabetic kidney disease. Am J Nephrol (2015) 0.78
Properdin and factor H production by human dendritic cells modulates their T-cell stimulatory capacity and is regulated by IFN-γ. Eur J Immunol (2017) 0.75
Differential regulation of C5a receptor 1 in innate immune cells during the allergic asthma effector phase. PLoS One (2017) 0.75
Complement component 3 deficiency prolongs MHC-II disparate skin allograft survival by increasing the CD4(+) CD25(+) regulatory T cells population. Sci Rep (2016) 0.75
C3d adjuvant effects are mediated through the activation of C3d-specific autoreactive T cells. Immunol Cell Biol (2014) 0.75
Complement Recognition Pathways in Renal Transplantation. J Am Soc Nephrol (2017) 0.75
TLR-Induced Murine Dendritic Cell (DC) Activation Requires DC-Intrinsic Complement. J Immunol (2017) 0.75
Screening for type 2 diabetes mellitus: a systematic review for the U.S. Preventive Services Task Force. Ann Intern Med (2015) 4.11
Determinants of BRAF mutations in primary melanomas. J Natl Cancer Inst (2003) 3.65
Local synthesis of complement component C3 regulates acute renal transplant rejection. Nat Med (2002) 3.39
Expression profile of microRNAs in serum: a fingerprint for esophageal squamous cell carcinoma. Clin Chem (2010) 2.34
Replacement of Oct4 by Tet1 during iPSC induction reveals an important role of DNA methylation and hydroxymethylation in reprogramming. Cell Stem Cell (2013) 2.17
Perfusion MRI and computerized cognitive test abnormalities in abstinent methamphetamine users. Psychiatry Res (2002) 2.02
Polarographic measurement of hydrogen sulfide production and consumption by mammalian tissues. Anal Biochem (2005) 1.97
Influence of donor C3 allotype on late renal-transplantation outcome. N Engl J Med (2006) 1.97
Factor I is required for the development of membranoproliferative glomerulonephritis in factor H-deficient mice. J Clin Invest (2008) 1.94
Fc-dependent depletion of activated T cells occurs through CD40L-specific antibody rather than costimulation blockade. Nat Med (2003) 1.92
Bis[1,3-bis-(1-benzyl-1H-benzimidazol-2-yl)-2-oxapropane]nickel(II) dipicrate-dimethyl-formamide-ethanol (1/2/0.25). Acta Crystallogr Sect E Struct Rep Online (2009) 1.89
Toll-like receptor 2 agonists exacerbate accelerated nephrotoxic nephritis. J Am Soc Nephrol (2006) 1.87
C3a mediates epithelial-to-mesenchymal transition in proteinuric nephropathy. J Am Soc Nephrol (2009) 1.85
Pivotal role of CD4+ T cells in renal fibrosis following ureteric obstruction. Kidney Int (2010) 1.83
Bis[1,3-bis-(1-benzyl-1H-benzimidazol-2-yl)-2-oxapropane]zinc(II) dipicrate dimethyl-formamide disolvate. Acta Crystallogr Sect E Struct Rep Online (2009) 1.76
A 16-week randomized clinical trial of 2000 international units daily vitamin D3 supplementation in black youth: 25-hydroxyvitamin D, adiposity, and arterial stiffness. J Clin Endocrinol Metab (2010) 1.69
Total synthesis of dimeric pyrrole-imidazole alkaloids: sceptrin, ageliferin, nagelamide e, oxysceptrin, nakamuric acid, and the axinellamine carbon skeleton. J Am Chem Soc (2007) 1.65
Recent patterns in population-based HIV prevalence in Swaziland. PLoS One (2013) 1.58
Acupoint-specific fMRI patterns in human brain. Neurosci Lett (2005) 1.57
The salient characteristics of the central effects of acupuncture needling: limbic-paralimbic-neocortical network modulation. Hum Brain Mapp (2009) 1.55
Protein farnesyltransferase and protein prenylation in Plasmodium falciparum. J Biol Chem (2002) 1.52
Functional magnetic resonance imaging activation of the brain in children: real acupoint versus sham acupoint. J Child Neurol (2010) 1.51
Effect of acupuncture on the brain in children with spastic cerebral palsy using functional neuroimaging (FMRI). J Child Neurol (2008) 1.51
Dried tube specimens: a simple and cost-effective method for preparation of HIV proficiency testing panels and quality control materials for use in resource-limited settings. J Virol Methods (2009) 1.48
Collectin-11 detects stress-induced L-fucose pattern to trigger renal epithelial injury. J Clin Invest (2016) 1.43
Effects of doctor-patient communication on quality of life among breast cancer patients in southern China. Asian Pac J Cancer Prev (2014) 1.41
Local extravascular pool of C3 is a determinant of postischemic acute renal failure. FASEB J (2006) 1.38
Local production and activation of complement up-regulates the allostimulatory function of dendritic cells through C3a-C3aR interaction. Blood (2007) 1.37
The retromer component SNX6 interacts with dynactin p150(Glued) and mediates endosome-to-TGN transport. Cell Res (2009) 1.33
Cyclic AMP plays a critical role in C3a-receptor-mediated regulation of dendritic cells in antigen uptake and T-cell stimulation. Blood (2008) 1.33
Suppression of murine cerebral F2-isoprostanes and F4-neuroprostanes from excitotoxicity and innate immune response in vivo by alpha- or gamma-tocopherol. J Chromatogr B Analyt Technol Biomed Life Sci (2005) 1.28
Multi-angle ratiometric approach to measure chemical exchange in amide proton transfer imaging. Magn Reson Med (2011) 1.28
Toll-like receptor 4 ligation on intrinsic renal cells contributes to the induction of antibody-mediated glomerulonephritis via CXCL1 and CXCL2. J Am Soc Nephrol (2007) 1.27
The role of complement in the early immune response to transplantation. Nat Rev Immunol (2012) 1.26
Chemical approaches to stem cell biology and therapeutics. Cell Stem Cell (2013) 1.25
Dendritic cell function in allostimulation is modulated by C5aR signaling. J Immunol (2009) 1.24
β-catenin as a potential key target for tumor suppression. Int J Cancer (2011) 1.23
Unusual microbial xylanases from insect guts. Appl Environ Microbiol (2004) 1.22
Aqua-[1,3-bis-(benzimidazol-2-yl)-2-oxapropane]-diethano-lmanganese(II) dipicrate ethanol disolvate. Acta Crystallogr Sect E Struct Rep Online (2010) 1.22
The role of anaphylatoxins C3a and C5a in regulating innate and adaptive immune responses. Inflamm Allergy Drug Targets (2009) 1.22
PG490-88, a derivative of triptolide, causes tumor regression and sensitizes tumors to chemotherapy. Mol Cancer Ther (2003) 1.19
Macrophages from C3-deficient mice have impaired potency to stimulate alloreactive T cells. Blood (2005) 1.19
Coronary sinus septal defect (unroofed coronary sinus): echocardiographic diagnosis and surgical treatment. Int J Cardiol (2012) 1.18
Homeostatic proliferation of lymphocytes results in augmented memory-like function and accelerated allograft rejection. J Immunol (2008) 1.17
Optimizing pulsed-chemical exchange saturation transfer imaging sequences. Magn Reson Med (2011) 1.16
High-quality gene assembly directly from unpurified mixtures of microarray-synthesized oligonucleotides. Nucleic Acids Res (2010) 1.14
Scaling law for noise variance and spatial resolution in differential phase contrast computed tomography. Med Phys (2011) 1.13
Short, enantioselective total synthesis of sceptrin and ageliferin by programmed oxaquadricyclane fragmentation. Angew Chem Int Ed Engl (2005) 1.13
CNS-specific therapy for ongoing EAE by silencing IL-17 pathway in astrocytes. Mol Ther (2012) 1.12
TLR2 stimulation of intrinsic renal cells in the induction of immune-mediated glomerulonephritis. J Immunol (2006) 1.12
Synthesis of complement protein C3 in the kidney is an important mediator of local tissue injury. FASEB J (2007) 1.11
Loss of immunity-supported senescence enhances susceptibility to hepatocellular carcinogenesis and progression in Toll-like receptor 2-deficient mice. Hepatology (2013) 1.11
Lack of beta-methylamino-l-alanine in brain from controls, AD, or Chamorros with PDC. Neurology (2005) 1.10
Inhibition of TLR2 promotes graft function in a murine model of renal transplant ischemia-reperfusion injury. FASEB J (2011) 1.08
Therapeutic strategy with a membrane-localizing complement regulator to increase the number of usable donor organs after prolonged cold storage. J Am Soc Nephrol (2006) 1.08
Nesfatin-1 action in the brain increases insulin sensitivity through Akt/AMPK/TORC2 pathway in diet-induced insulin resistance. Diabetes (2012) 1.08
Complement in organ transplantation. Curr Opin Organ Transplant (2010) 1.08
The development of a selective cyclin-dependent kinase inhibitor that shows antitumor activity. Cancer Res (2009) 1.08
Common genetic variants in complement genes other than CFH, CD46 and the CFHRs are not associated with aHUS. Mol Immunol (2011) 1.06
Multicontrast x-ray computed tomography imaging using Talbot-Lau interferometry without phase stepping. Med Phys (2012) 1.06
Human leukocyte antigen G expression: as a significant prognostic indicator for patients with colorectal cancer. Mod Pathol (2007) 1.06
Deficiency of C4 from donor or recipient mouse fails to prevent renal allograft rejection. Am J Pathol (2006) 1.06
Synthesis and anti-tumor activity of novel ethyl 3-aryl-4-oxo-3,3a,4,6-tetrahydro-1H-furo[3,4-c]pyran-3a-carboxylates. Bioorg Med Chem Lett (2011) 1.06
Trends in esophageal cancer mortality in China during 1987-2009: age, period and birth cohort analyzes. Cancer Epidemiol (2012) 1.05
Characterizing tumor response to chemotherapy at various length scales using temporal diffusion spectroscopy. PLoS One (2012) 1.05
C3a and C5a promote renal ischemia-reperfusion injury. J Am Soc Nephrol (2012) 1.05
Fc gamma RIII and Fc gamma RIV are indispensable for acute glomerular inflammation induced by switch variant monoclonal antibodies. J Immunol (2008) 1.04
Role of the complement system in rejection. Curr Opin Immunol (2003) 1.04
Expression of human leucocyte antigen G (HLA-G) is associated with prognosis in non-small cell lung cancer. Lung Cancer (2007) 1.03
Mechanisms of disease: the complement system in renal injury--new ways of looking at an old foe. Nat Clin Pract Nephrol (2007) 1.03
The radial diffusivity and magnetization transfer pool size ratio are sensitive markers for demyelination in a rat model of type III multiple sclerosis (MS) lesions. Neuroimage (2013) 1.01
The use of eculizumab in renal transplantation. Clin Transplant (2013) 1.00
Prognostic value of vascular endothelial growth factor expression in patients with esophageal cancer: a systematic review and meta-analysis. Cancer Epidemiol Biomarkers Prev (2012) 1.00
Grating based x-ray differential phase contrast imaging without mechanical phase stepping. Opt Express (2014) 1.00
Visual attention deficits in Alzheimer's disease: an fMRI study. Neurosci Lett (2005) 1.00
The relative importance of local and systemic complement production in ischaemia, transplantation and other pathologies. Mol Immunol (2007) 1.00
Hepatitis C virus NS2 protein triggers endoplasmic reticulum stress and suppresses its own viral replication. J Hepatol (2010) 0.99
CD59a deficiency exacerbates ischemia-reperfusion injury in mice. Am J Pathol (2004) 0.98
Effective protection and controlled release of insulin by cationic beta-cyclodextrin polymers from alginate/chitosan nanoparticles. Int J Pharm (2010) 0.98
Nontransgenic hyperexpression of a complement regulator in donor kidney modulates transplant ischemia/reperfusion damage, acute rejection, and chronic nephropathy. Am J Pathol (2003) 0.97
Functional modulation of human monocytes derived DCs by anaphylatoxins C3a and C5a. Immunobiology (2011) 0.97