Published in Biochem Biophys Res Commun on May 07, 2007
Molecular mechanism for the umami taste synergism. Proc Natl Acad Sci U S A (2008) 1.53
Characterization of the beta-D-glucopyranoside binding site of the human bitter taste receptor hTAS2R16. J Biol Chem (2010) 1.14
Characterization of the modes of binding between human sweet taste receptor and low-molecular-weight sweet compounds. PLoS One (2012) 1.09
Targeting G protein coupled receptor-related pathways as emerging molecular therapies. Saudi Pharm J (2013) 1.06
Key amino acid residues involved in multi-point binding interactions between brazzein, a sweet protein, and the T1R2-T1R3 human sweet receptor. J Mol Biol (2010) 1.02
Orosensory detection of sucrose, maltose, and glucose is severely impaired in mice lacking T1R2 or T1R3, but Polycose sensitivity remains relatively normal. Am J Physiol Regul Integr Comp Physiol (2012) 0.99
Two distinct determinants of ligand specificity in T1R1/T1R3 (the umami taste receptor). J Biol Chem (2013) 0.95
Molecular mechanisms of taste transduction in vertebrates. Odontology (2009) 0.94
The functional role of the T1R family of receptors in sweet taste and feeding. Physiol Behav (2011) 0.94
Isolation and characterization of microsatellite markers and analysis of genetic variability in Curculigo latifolia Dryand. Mol Biol Rep (2012) 0.93
An efficient in vitro plantlet regeneration from shoot tip cultures of Curculigo latifolia, a medicinal plant. ScientificWorldJournal (2014) 0.88
Identification and modulation of the key amino acid residue responsible for the pH sensitivity of neoculin, a taste-modifying protein. PLoS One (2011) 0.86
Human sweet taste receptor mediates acid-induced sweetness of miraculin. Proc Natl Acad Sci U S A (2011) 0.83
Reduced sweetness of a monellin (MNEI) mutant results from increased protein flexibility and disruption of a distant poly-(L-proline) II helix. Chem Senses (2011) 0.79
Molecular mechanisms for sweet-suppressing effect of gymnemic acids. J Biol Chem (2014) 0.79
A Hypersweet Protein: Removal of The Specific Negative Charge at Asp21 Enhances Thaumatin Sweetness. Sci Rep (2016) 0.76
Identification of key neoculin residues responsible for the binding and activation of the sweet taste receptor. Sci Rep (2015) 0.75
Structural Basis of pH Dependence of Neoculin, a Sweet Taste-Modifying Protein. PLoS One (2015) 0.75
Distinct human and mouse membrane trafficking systems for sweet taste receptors T1r2 and T1r3. PLoS One (2014) 0.75
The cephalic phase insulin response to nutritive and low-calorie sweeteners in solid and beverage form. Physiol Behav (2017) 0.75
Tie2/angiopoietin-1 signaling regulates hematopoietic stem cell quiescence in the bone marrow niche. Cell (2004) 12.67
Foxo3a is essential for maintenance of the hematopoietic stem cell pool. Cell Stem Cell (2007) 5.94
PML regulates apoptosis at endoplasmic reticulum by modulating calcium release. Science (2010) 3.21
Arteriolar niches maintain haematopoietic stem cell quiescence. Nature (2013) 3.07
Systemic elevation of PTEN induces a tumor-suppressive metabolic state. Cell (2012) 2.39
The oncogenic microRNA miR-22 targets the TET2 tumor suppressor to promote hematopoietic stem cell self-renewal and transformation. Cell Stem Cell (2013) 2.33
Fbxw7 acts as a critical fail-safe against premature loss of hematopoietic stem cells and development of T-ALL. Genes Dev (2008) 2.12
The use of simulated patients in medical education: AMEE Guide No 42. Med Teach (2009) 2.09
Plexin-a4 mediates axon-repulsive activities of both secreted and transmembrane semaphorins and plays roles in nerve fiber guidance. J Neurosci (2005) 1.89
Function of oxidative stress in the regulation of hematopoietic stem cell-niche interaction. Biochem Biophys Res Commun (2007) 1.66
A systematic genome-wide screen for mutations affecting organogenesis in Medaka, Oryzias latipes. Mech Dev (2004) 1.65
A metabolic prosurvival role for PML in breast cancer. J Clin Invest (2012) 1.57
VmrA, a member of a novel class of Na(+)-coupled multidrug efflux pumps from Vibrio parahaemolyticus. J Bacteriol (2002) 1.57
Catechin, a green tea component, rapidly induces apoptosis of myeloid leukemic cells via modulation of reactive oxygen species production in vitro and inhibits tumor growth in vivo. Haematologica (2005) 1.55
Ovarian endometriosis showing decidual change and Arias-Stella reaction with biotin-containing intranuclear inclusions. Acta Cytol (2003) 1.49
An H(+)-coupled multidrug efflux pump, PmpM, a member of the MATE family of transporters, from Pseudomonas aeruginosa. J Bacteriol (2004) 1.42
Muscle RING-finger protein-1 (MuRF1) as a connector of muscle energy metabolism and protein synthesis. J Mol Biol (2007) 1.41
Designed ATRA analogue active against ATRA-resistant acute promyelocytic leukemia cells having a single nucleotide substitution in their retinoic acid receptor. Leuk Res (2006) 1.40
LRF is an essential downstream target of GATA1 in erythroid development and regulates BIM-dependent apoptosis. Dev Cell (2009) 1.39
A new member of the tripartite multidrug efflux pumps, MexVW-OprM, in Pseudomonas aeruginosa. J Antimicrob Chemother (2003) 1.29
Identification of essential amino acid residues of the NorM Na+/multidrug antiporter in Vibrio parahaemolyticus. J Bacteriol (2005) 1.27
Characterization of ligands for fish taste receptors. J Neurosci (2007) 1.26
Gene cloning and characterization of VcrM, a Na+-coupled multidrug efflux pump, from Vibrio cholerae non-O1. Microbiol Immunol (2003) 1.23
Green tea component, catechin, induces apoptosis of human malignant B cells via production of reactive oxygen species. Clin Cancer Res (2005) 1.23
Mechanisms of action of corilagin and tellimagrandin I that remarkably potentiate the activity of beta-lactams against methicillin-resistant Staphylococcus aureus. Microbiol Immunol (2004) 1.23
Two families of candidate taste receptors in fishes. Mech Dev (2005) 1.22
The cytoplasmic NPM mutant induces myeloproliferation in a transgenic mouse model. Blood (2009) 1.21
Molecular cloning and characterization of an ABC multidrug efflux pump, VcaM, in Non-O1 Vibrio cholerae. Antimicrob Agents Chemother (2003) 1.19
Zerumbone, a bioactive sesquiterpene, induces G2/M cell cycle arrest and apoptosis in leukemia cells via a Fas- and mitochondria-mediated pathway. Cancer Sci (2007) 1.18
Reactive oxygen species induce chondrocyte hypertrophy in endochondral ossification. J Exp Med (2007) 1.16
Antiobesity effects of Bifidobacterium breve strain B-3 supplementation in a mouse model with high-fat diet-induced obesity. Biosci Biotechnol Biochem (2010) 1.16
Characterization of the beta-D-glucopyranoside binding site of the human bitter taste receptor hTAS2R16. J Biol Chem (2010) 1.14
Genetic tracing of the gustatory and trigeminal neural pathways originating from T1R3-expressing taste receptor cells and solitary chemoreceptor cells. Mol Cell Neurosci (2008) 1.13
Crystal structure of glucansucrase from the dental caries pathogen Streptococcus mutans. J Mol Biol (2011) 1.13
Possible regulation of the conventional calpain system by skeletal muscle-specific calpain, p94/calpain 3. J Biol Chem (2003) 1.11
Modulating effect of sesamin, a functional lignan in sesame seeds, on the transcription levels of lipid- and alcohol-metabolizing enzymes in rat liver: a DNA microarray study. Biosci Biotechnol Biochem (2005) 1.11
Skn-1a (Pou2f3) specifies taste receptor cell lineage. Nat Neurosci (2011) 1.09
Characterization of the modes of binding between human sweet taste receptor and low-molecular-weight sweet compounds. PLoS One (2012) 1.09
Plant seed cystatins and their target enzymes of endogenous and exogenous origin. J Agric Food Chem (2002) 1.08
Aromatase inhibitor treatment of breast cancer cells increases the expression of let-7f, a microRNA targeting CYP19A1. J Pathol (2012) 1.07
Suppression by licorice flavonoids of abdominal fat accumulation and body weight gain in high-fat diet-induced obese C57BL/6J mice. Biosci Biotechnol Biochem (2007) 1.07
OPA1 expression in the normal rat retina and optic nerve. J Comp Neurol (2005) 1.06
Ameliorative effects of mulberry (Morus alba L.) leaves on hyperlipidemia in rats fed a high-fat diet: induction of fatty acid oxidation, inhibition of lipogenesis, and suppression of oxidative stress. Biosci Biotechnol Biochem (2010) 1.06
Functional cloning and characterization of a multidrug efflux pump, mexHI-opmD, from a Pseudomonas aeruginosa mutant. Antimicrob Agents Chemother (2003) 1.05
Aquaporin-11 knockout mice and polycystic kidney disease animals share a common mechanism of cyst formation. FASEB J (2008) 1.04
Protective role of the leukotriene B4 receptor BLT2 in murine inflammatory colitis. FASEB J (2010) 1.04
Molecular cloning and characterization of the HmrM multidrug efflux pump from Haemophilus influenzae Rd. Microbiol Immunol (2003) 1.03
Calpain 8/nCL-2 and calpain 9/nCL-4 constitute an active protease complex, G-calpain, involved in gastric mucosal defense. PLoS Genet (2010) 1.03
Differential regulation of intestinal lipid metabolism-related genes in obesity-resistant A/J vs. obesity-prone C57BL/6J mice. Am J Physiol Endocrinol Metab (2006) 1.02
Suppressed disassembly of autolyzing p94/CAPN3 by N2A connectin/titin in a genetic reporter system. J Biol Chem (2006) 1.01
The nuclear bodies inside out: PML conquers the cytoplasm. Curr Opin Cell Biol (2011) 1.01
Complete genome sequence of Helicobacter cinaedi strain PAGU611, isolated in a case of human bacteremia. J Bacteriol (2012) 1.01
Ingested cocoa can prevent high-fat diet-induced obesity by regulating the expression of genes for fatty acid metabolism. Nutrition (2005) 1.00
Acetic acid activates PKD1L3-PKD2L1 channel--a candidate sour taste receptor. Biochem Biophys Res Commun (2009) 1.00
Dynamic distribution of muscle-specific calpain in mice has a key role in physical-stress adaptation and is impaired in muscular dystrophy. J Clin Invest (2010) 0.99
Functional diversity of bitter taste receptor TAS2R16 in primates. Biol Lett (2012) 0.99
Detection of Epstein-Barr virus-encoded small RNA-expressed myofibroblasts and IgG4-producing plasma cells in sclerosing angiomatoid nodular transformation of the spleen. Virchows Arch (2008) 0.99
The Hsp90 inhibitor geldanamycin abrogates colocalization of eIF4E and eIF4E-transporter into stress granules and association of eIF4E with eIF4G. J Biol Chem (2009) 0.98
Effect of flavonol glycoside in mulberry (Morus alba L.) leaf on glucose metabolism and oxidative stress in liver in diet-induced obese mice. J Sci Food Agric (2010) 0.97
Taste receptor cells express voltage-dependent potassium channels in a cell age-specific manner. Chem Senses (2006) 0.97
Group IIA phospholipase A(2) is coexpressed with SNAP-25 in mature taste receptor cells of rat circumvallate papillae. J Comp Neurol (2006) 0.97
Two distinct determinants of ligand specificity in T1R1/T1R3 (the umami taste receptor). J Biol Chem (2013) 0.95
Evaluation of the Pichia pastoris expression system for the production of GPCRs for structural analysis. Microb Cell Fact (2011) 0.95
Clinical evaluation of the efficacy of removing microorganisms to disinfect patient-derived dental impressions. Int J Prosthodont (2009) 0.95
Acid-induced sweetness of neoculin is ascribed to its pH-dependent agonistic-antagonistic interaction with human sweet taste receptor. FASEB J (2008) 0.95
Treatment outcome of high-dose image-guided intensity-modulated radiotherapy using intra-prostate fiducial markers for localized prostate cancer at a single institute in Japan. Radiat Oncol (2012) 0.95
Evaluation of a communication skills seminar for students in a Japanese medical school: a non-randomized controlled study. BMC Med Educ (2004) 0.95
The role of catecholamines in the pathogenesis of neurogenic pulmonary edema associated with subarachnoid hemorrhage. Acta Neurochir (Wien) (2012) 0.95
Neoculin as a new taste-modifying protein occurring in the fruit of Curculigo latifolia. Biosci Biotechnol Biochem (2004) 0.94
Netrin 1 regulates ventral tangential migration of guidepost neurons in the lateral olfactory tract. Development (2006) 0.94
Evaluation of the bitterness of green tea catechins by a cell-based assay with the human bitter taste receptor hTAS2R39. Biochem Biophys Res Commun (2011) 0.94
Amiloride reduces the sweet taste intensity by inhibiting the human sweet taste receptor. Biochem Biophys Res Commun (2010) 0.93
Suppression of estrogen actions in human lung cancer. Mol Cell Endocrinol (2011) 0.93
Artepillin C, a major ingredient of Brazilian propolis, induces a pungent taste by activating TRPA1 channels. PLoS One (2012) 0.92
Dietary protein quantity and quality affect rat hepatic gene expression. J Nutr (2002) 0.92
Up-regulation of genes related to the ubiquitin-proteasome system in the brown adipose tissue of 24-h-fasted rats. Biosci Biotechnol Biochem (2008) 0.92
Co-expression of estrogen receptor beta and aromatase in Japanese lung cancer patients: gender-dependent clinical outcome. Life Sci (2012) 0.91
A truncated AdeS kinase protein generated by ISAba1 insertion correlates with tigecycline resistance in Acinetobacter baumannii. PLoS One (2012) 0.91
Branchiibius cervicis sp. nov., a novel species isolated from patients with atopic dermatitis. Syst Appl Microbiol (2011) 0.91
Salicylic acid carboxyl methyltransferase induced in hairy root cultures of Atropa belladonna after treatment with exogeneously added salicylic acid. Plant Cell Physiol (2002) 0.91