Published in Development on May 16, 2007
Directed differentiation of human pluripotent stem cells into intestinal tissue in vitro. Nature (2010) 5.81
Generation and regeneration of cells of the liver and pancreas. Science (2008) 4.21
Stage-specific signaling through TGFβ family members and WNT regulates patterning and pancreatic specification of human pluripotent stem cells. Development (2011) 2.82
The emerging genetic architecture of type 2 diabetes. Cell Metab (2008) 2.77
Vertebrate endoderm development and organ formation. Annu Rev Cell Dev Biol (2009) 2.67
Pioneer factors, genetic competence, and inductive signaling: programming liver and pancreas progenitors from the endoderm. Cold Spring Harb Symp Quant Biol (2008) 2.34
Liver stem cells and hepatocellular carcinoma. Hepatology (2009) 2.27
Dynamic signaling network for the specification of embryonic pancreas and liver progenitors. Science (2009) 2.12
Human hepatic stem cell and maturational liver lineage biology. Hepatology (2011) 1.99
beta-Catenin promotes respiratory progenitor identity in mouse foregut. Proc Natl Acad Sci U S A (2009) 1.75
Beta-catenin deletion in hepatoblasts disrupts hepatic morphogenesis and survival during mouse development. Hepatology (2008) 1.72
Extension of type 2 diabetes genome-wide association scan results in the diabetes prevention program. Diabetes (2008) 1.71
Generating human intestinal tissue from pluripotent stem cells in vitro. Nat Protoc (2011) 1.65
Sfrp5 coordinates foregut specification and morphogenesis by antagonizing both canonical and noncanonical Wnt11 signaling. Genes Dev (2008) 1.63
Vertebrate intestinal endoderm development. Dev Dyn (2011) 1.41
New school in liver development: lessons from zebrafish. Hepatology (2009) 1.36
Stem cells in gastroenterology and hepatology. Nat Rev Gastroenterol Hepatol (2009) 1.23
The intestine-specific transcription factor Cdx2 inhibits beta-catenin/TCF transcriptional activity by disrupting the beta-catenin-TCF protein complex. Carcinogenesis (2009) 1.16
Wnt signaling specifies and patterns intestinal endoderm. Mech Dev (2011) 1.14
Generation of beta cells from human pluripotent stem cells: Potential for regenerative medicine. Semin Cell Dev Biol (2012) 1.12
PRH/Hex: an oligomeric transcription factor and multifunctional regulator of cell fate. Biochem J (2008) 1.11
Suppression of Alk8-mediated Bmp signaling cell-autonomously induces pancreatic beta-cells in zebrafish. Proc Natl Acad Sci U S A (2009) 1.10
How to make an intestine. Development (2014) 1.10
Retinoic acid signaling organizes endodermal organ specification along the entire antero-posterior axis. PLoS One (2009) 1.05
Wnt/beta-catenin signaling in hepatic organogenesis. Organogenesis (2008) 1.05
Patterning and plasticity in development of the respiratory lineage. Dev Dyn (2010) 1.05
Wntless is required for peripheral lung differentiation and pulmonary vascular development. Dev Biol (2013) 1.03
An endothelial cell niche induces hepatic specification through dual repression of Wnt and Notch signaling. Stem Cells (2011) 1.03
Liver development, regeneration, and carcinogenesis. J Biomed Biotechnol (2010) 1.02
Interplay between Wnt2 and Wnt2bb controls multiple steps of early foregut-derived organ development. Development (2011) 1.01
Xenopus pancreas development. Dev Dyn (2009) 0.99
The what, where, when and how of Wnt/β-catenin signaling in pancreas development. Organogenesis (2008) 0.98
A gene regulatory network controlling hhex transcription in the anterior endoderm of the organizer. Dev Biol (2011) 0.97
Restriction of hepatic competence by Fgf signaling. Development (2011) 0.97
New approaches in the differentiation of human embryonic stem cells and induced pluripotent stem cells toward hepatocytes. Stem Cell Rev (2011) 0.97
Role and regulation of β-catenin signaling during physiological liver growth. Gene Expr (2014) 0.95
Sizzled-tolloid interactions maintain foregut progenitors by regulating fibronectin-dependent BMP signaling. Dev Cell (2012) 0.95
Promoting ectopic pancreatic fates: pancreas development and future diabetes therapies. Clin Genet (2008) 0.95
Orchestrating liver development. Development (2015) 0.94
Suppression of Bmp4 signaling by the zinc-finger repressors Osr1 and Osr2 is required for Wnt/β-catenin-mediated lung specification in Xenopus. Development (2012) 0.93
Liver-specific β-catenin knockout mice have bile canalicular abnormalities, bile secretory defect, and intrahepatic cholestasis. Hepatology (2010) 0.93
The mitochondrial import gene tomm22 is specifically required for hepatocyte survival and provides a liver regeneration model. Dis Model Mech (2010) 0.93
Organoid Models of Human Gastrointestinal Development and Disease. Gastroenterology (2016) 0.92
Different thresholds of Wnt-Frizzled 7 signaling coordinate proliferation, morphogenesis and fate of endoderm progenitor cells. Dev Biol (2013) 0.92
Molecular pathways controlling pancreas induction. Semin Cell Dev Biol (2012) 0.91
Pancreas cell fate. Birth Defects Res C Embryo Today (2009) 0.91
Molecular biology of pancreatic ductal adenocarcinoma progression: aberrant activation of developmental pathways. Prog Mol Biol Transl Sci (2010) 0.91
BrunoL1 regulates endoderm proliferation through translational enhancement of cyclin A2 mRNA. Dev Biol (2010) 0.91
Interaction between Hhex and SOX13 modulates Wnt/TCF activity. J Biol Chem (2009) 0.90
Transcriptional networks in liver and intestinal development. Cold Spring Harb Perspect Biol (2012) 0.89
Caudal homeobox protein Cdx-2 cooperates with Wnt pathway to regulate claudin-1 expression in colon cancer cells. PLoS One (2012) 0.88
Growth factor- and cytokine-driven pathways governing liver stemness and differentiation. World J Gastroenterol (2010) 0.88
Homeoprotein hhex-induced conversion of intestinal to ventral pancreatic precursors results in the formation of giant pancreata in Xenopus embryos. Proc Natl Acad Sci U S A (2012) 0.88
Generating human intestinal tissues from pluripotent stem cells to study development and disease. EMBO J (2015) 0.88
Wnt signaling in gut organogenesis. Organogenesis (2008) 0.86
Sfrp5 modulates both Wnt and BMP signaling and regulates gastrointestinal organogenesis [corrected] in the zebrafish, Danio rerio. PLoS One (2013) 0.85
High oxygen condition facilitates the differentiation of mouse and human pluripotent stem cells into pancreatic progenitors and insulin-producing cells. J Biol Chem (2014) 0.84
Analysis of mPygo2 mutant mice suggests a requirement for mesenchymal Wnt signaling in pancreatic growth and differentiation. Dev Biol (2008) 0.84
Xenopus insm1 is essential for gastrointestinal and pancreatic endocrine cell development. Dev Dyn (2009) 0.84
Cellular and molecular basis of liver development. Compr Physiol (2013) 0.84
Specification of hepatopancreas progenitors in zebrafish by hnf1ba and wnt2bb. Development (2013) 0.83
Identification of genes expressed in the migrating primitive myeloid lineage of Xenopus laevis. Dev Dyn (2015) 0.83
A gutsy task: generating intestinal tissue from human pluripotent stem cells. Dig Dis Sci (2013) 0.83
Calpain induces N-terminal truncation of β-catenin in normal murine liver development: diagnostic implications in hepatoblastomas. J Biol Chem (2012) 0.83
Distinct requirements for beta-catenin in pancreatic epithelial growth and patterning. Dev Biol (2014) 0.82
A Molecular atlas of Xenopus respiratory system development. Dev Dyn (2014) 0.82
The new generation of beta-cells: replication, stem cell differentiation, and the role of small molecules. Rev Diabet Stud (2010) 0.82
Stage-specific regulation of the WNT/β-catenin pathway enhances differentiation of hESCs into hepatocytes. J Hepatol (2016) 0.82
Building additional complexity to in vitro-derived intestinal tissues. Stem Cell Res Ther (2013) 0.81
NKX2-1 activation by SMAD2 signaling after definitive endoderm differentiation in human embryonic stem cell. Stem Cells Dev (2013) 0.81
Derivation of Endodermal Progenitors From Pluripotent Stem Cells. J Cell Physiol (2015) 0.80
Phylogenetic and regulatory region analysis of Wnt5 genes reveals conservation of a regulatory module with putative implication in pancreas development. Biol Direct (2010) 0.80
Ethanol negatively regulates hepatic differentiation of hESC by inhibition of the MAPK/ERK signaling pathway in vitro. PLoS One (2014) 0.80
Wnt/β-catenin signaling cell-autonomously converts non-hepatic endodermal cells to a liver fate. Biol Open (2012) 0.80
Stem cell differentiation and human liver disease. World J Gastroenterol (2012) 0.79
Recent advances in stem cell research for the treatment of diabetes. World J Stem Cells (2009) 0.79
Retinoic acid-activated Ndrg1a represses Wnt/β-catenin signaling to allow Xenopus pancreas, oesophagus, stomach, and duodenum specification. PLoS One (2013) 0.79
Xenopus staufen2 is required for anterior endodermal organ formation. Genesis (2012) 0.79
Iterative use of nuclear receptor Nr5a2 regulates multiple stages of liver and pancreas development. Dev Biol (2016) 0.78
The septum transversum mesenchyme induces gall bladder development. Biol Open (2013) 0.78
Enhancement of hepatocyte differentiation from human embryonic stem cells by Chinese medicine Fuzhenghuayu. Sci Rep (2016) 0.78
Dose-dependent nuclear β-catenin response segregates endomesoderm along the sea star primary axis. Development (2015) 0.78
Xenopus as a Model for GI/Pancreas Disease. Curr Pathobiol Rep (2015) 0.77
Advances in Liver Regeneration: Revisiting Hepatic Stem/Progenitor Cells and Their Origin. Stem Cells Int (2015) 0.77
Stomach development, stem cells and disease. Development (2016) 0.77
Wnt signaling and specification of the respiratory endoderm. Cell Cycle (2010) 0.77
FGF2 mediates hepatic progenitor cell formation during human pluripotent stem cell differentiation by inducing the WNT antagonist NKD1. Genes Dev (2015) 0.77
Endothelium-derived essential signals involved in pancreas organogenesis. World J Exp Med (2015) 0.76
Frogs as integrative models for understanding digestive organ development and evolution. Semin Cell Dev Biol (2016) 0.76
Primary cilia in pancreatic development and disease. Birth Defects Res C Embryo Today (2014) 0.76
Syndecan4 coordinates Wnt/JNK and BMP signaling to regulate foregut progenitor development. Dev Biol (2016) 0.76
Role of β-catenin in development of bile ducts. Differentiation (2016) 0.76
Lzts2 regulates embryonic cell movements and dorsoventral patterning through interaction with and export of nuclear β-catenin in zebrafish. J Biol Chem (2011) 0.76
A process engineering approach to increase organoid yield. Development (2017) 0.75
Direct lineage reprogramming via pioneer factors; a detour through developmental gene regulatory networks. Development (2016) 0.75
Scalable Differentiation of Human iPSCs in a Multicellular Spheroid-based 3D Culture into Hepatocyte-like Cells through Direct Wnt/β-catenin Pathway Inhibition. Sci Rep (2016) 0.75
Expression kinetics of hepatic progenitor markers in cellular models of human liver development recapitulating hepatocyte and biliary cell fate commitment. Exp Biol Med (Maywood) (2016) 0.75
Misregulation of the proline rich homeodomain (PRH/HHEX) protein in cancer cells and its consequences for tumour growth and invasion. Cell Biosci (2016) 0.75
The use of cellular technologies in treatment of liver pathologies. Acta Naturae (2012) 0.75
In vitro patterning of pluripotent stem cell-derived intestine recapitulates in vivo human development. Development (2016) 0.75
Directed differentiation of human pluripotent stem cells into intestinal tissue in vitro. Nature (2010) 5.81
The genome of the Western clawed frog Xenopus tropicalis. Science (2010) 4.70
Sox17 and Sox4 differentially regulate beta-catenin/T-cell factor activity and proliferation of colon carcinoma cells. Mol Cell Biol (2007) 2.67
Xenbase: gene expression and improved integration. Nucleic Acids Res (2009) 2.38
Techniques and probes for the study of Xenopus tropicalis development. Dev Dyn (2002) 2.34
Sox17 and beta-catenin cooperate to regulate the transcription of endodermal genes. Development (2004) 2.33
Transdifferentiation of ciliated cells during repair of the respiratory epithelium. Am J Respir Cell Mol Biol (2005) 2.12
Mutations in cardiac T-box factor gene TBX20 are associated with diverse cardiac pathologies, including defects of septation and valvulogenesis and cardiomyopathy. Am J Hum Genet (2007) 1.97
Cardiac T-box factor Tbx20 directly interacts with Nkx2-5, GATA4, and GATA5 in regulation of gene expression in the developing heart. Dev Biol (2003) 1.89
Defining a large set of full-length clones from a Xenopus tropicalis EST project. Dev Biol (2004) 1.87
Sfrp5 coordinates foregut specification and morphogenesis by antagonizing both canonical and noncanonical Wnt11 signaling. Genes Dev (2008) 1.63
Interactions between SOX factors and Wnt/beta-catenin signaling in development and disease. Dev Dyn (2010) 1.53
Xenbase: expansion and updates of the Xenopus model organism database. Nucleic Acids Res (2012) 1.49
Sox17 influences the differentiation of respiratory epithelial cells. Dev Biol (2006) 1.33
Global analysis of the transcriptional network controlling Xenopus endoderm formation. Development (2006) 1.22
A new method to remove hybridization bias for interspecies comparison of global gene expression profiles uncovers an association between mRNA sequence divergence and differential gene expression in Xenopus. Nucleic Acids Res (2006) 1.17
Solution structure and backbone dynamics of the KH-QUA2 region of the Xenopus STAR/GSG quaking protein. J Mol Biol (2005) 1.11
Sox17 promotes cell cycle progression and inhibits TGF-beta/Smad3 signaling to initiate progenitor cell behavior in the respiratory epithelium. PLoS One (2009) 1.10
Rasip1 is required for endothelial cell motility, angiogenesis and vessel formation. Dev Biol (2009) 1.10
spib is required for primitive myeloid development in Xenopus. Blood (2008) 1.05
Enhanced XAO: the ontology of Xenopus anatomy and development underpins more accurate annotation of gene expression and queries on Xenbase. J Biomed Semantics (2013) 1.02
A New Nomenclature of Xenopus laevis Chromosomes Based on the Phylogenetic Relationship to Silurana/Xenopus tropicalis. Cytogenet Genome Res (2015) 1.01
Purification and high-resolution top-down mass spectrometric characterization of human salivary α-amylase. Anal Chem (2012) 1.00
Structure of protein related to Dan and Cerberus: insights into the mechanism of bone morphogenetic protein antagonism. Structure (2013) 0.98
A gene regulatory network controlling hhex transcription in the anterior endoderm of the organizer. Dev Biol (2011) 0.97
Members of the DAN family are BMP antagonists that form highly stable noncovalent dimers. J Mol Biol (2012) 0.97
Smad2 and Smad3 coordinately regulate craniofacial and endodermal development. Dev Biol (2004) 0.96
Sizzled-tolloid interactions maintain foregut progenitors by regulating fibronectin-dependent BMP signaling. Dev Cell (2012) 0.95
Suppression of Bmp4 signaling by the zinc-finger repressors Osr1 and Osr2 is required for Wnt/β-catenin-mediated lung specification in Xenopus. Development (2012) 0.93
FoxI1e activates ectoderm formation and controls cell position in the Xenopus blastula. Development (2007) 0.93
Novel gene expression domains reveal early patterning of the Xenopus endoderm. Gene Expr Patterns (2003) 0.92
Improved cre reporter transgenic Xenopus. Dev Dyn (2009) 0.92
Different thresholds of Wnt-Frizzled 7 signaling coordinate proliferation, morphogenesis and fate of endoderm progenitor cells. Dev Biol (2013) 0.92
Molecular control of liver development. Clin Liver Dis (2006) 0.91
Inner arm dynein 1 is essential for Ca++-dependent ciliary reversals in Tetrahymena thermophila. Cell Motil Cytoskeleton (2002) 0.86
Prolonged FGF signaling is necessary for lung and liver induction in Xenopus. BMC Dev Biol (2012) 0.86
The core endodermal gene network of vertebrates: combining developmental precision with evolutionary flexibility. Bioessays (2008) 0.84
Negative regulation of Smad2 by PIASy is required for proper Xenopus mesoderm formation. Development (2004) 0.84
New doxycycline-inducible transgenic lines in Xenopus. Dev Dyn (2011) 0.84
Antimicrobial properties of commercial annatto extracts against selected pathogenic, lactic acid, and spoilage microorganisms. J Food Prot (2003) 0.84
A dynamic requirement for community interactions during Xenopus myogenesis. Int J Dev Biol (2002) 0.83
Role of cystathionine beta-lyase in catabolism of amino acids to sulfur volatiles by genetic variants of Lactobacillus helveticus CNRZ 32. Appl Environ Microbiol (2007) 0.83
CRIM1 complexes with ß-catenin and cadherins, stabilizes cell-cell junctions and is critical for neural morphogenesis. PLoS One (2012) 0.83
Overexpression of Lactobacillus casei D-hydroxyisocaproic acid dehydrogenase in cheddar cheese. Appl Environ Microbiol (2004) 0.82
A Molecular atlas of Xenopus respiratory system development. Dev Dyn (2014) 0.82
Determining the impact of varying levels of cherry powder and starter culture on quality and sensory attributes of indirectly cured, emulsified cooked sausages. Meat Sci (2011) 0.82
The efficiency of Xenopus primordial germ cell migration depends on the germplasm mRNA encoding the PDZ domain protein Grip2. Differentiation (2007) 0.82
Comparison of volatile compounds in water- and oil-soluble annatto (Bixa orellana L.) extracts. J Agric Food Chem (2002) 0.81
Bioautography and chemical characterization of antimicrobial compound(s) in commercial water-soluble annatto extracts. J Agric Food Chem (2005) 0.81
Par6b regulates the dynamics of apicobasal polarity during development of the stratified Xenopus epidermis. PLoS One (2013) 0.79
Gene regulatory networks governing lung specification. J Cell Biochem (2014) 0.79
Molecular components of the endoderm specification pathway in Xenopus tropicalis. Dev Dyn (2003) 0.78
Reducing sodium levels in frankfurters using a natural flavor enhancer. Meat Sci (2012) 0.78
The Xenbase literature curation process. Database (Oxford) (2013) 0.76
Organogenesis: making pancreas from liver. Curr Biol (2003) 0.75
Partitioning behavior of Alkan-1-ols between milkfat and aqueous phases as influenced by temperature. J Agric Food Chem (2005) 0.75
Reducing sodium levels in frankfurters using naturally brewed soy sauce. Meat Sci (2011) 0.75
Homogenization and lipase treatment of milk and resulting methyl ketone generation in blue cheese. J Agric Food Chem (2014) 0.75