Published in Cell Calcium on May 22, 2007
TRPM8 is the principal mediator of menthol-induced analgesia of acute and inflammatory pain. Pain (2013) 1.09
Expression of TRPC6 channels in human epithelial breast cancer cells. BMC Cancer (2008) 1.08
Systematic and quantitative mRNA expression analysis of TRP channel genes at the single trigeminal and dorsal root ganglion level in mouse. BMC Neurosci (2013) 1.05
Alternative splicing of a protein domain indispensable for function of transient receptor potential melastatin 3 (TRPM3) ion channels. J Biol Chem (2012) 1.02
α2δ-1 gene deletion affects somatosensory neuron function and delays mechanical hypersensitivity in response to peripheral nerve damage. J Neurosci (2013) 0.98
Voltage- and cold-dependent gating of single TRPM8 ion channels. J Gen Physiol (2011) 0.95
Chemosensory properties of the trigeminal system. ACS Chem Neurosci (2010) 0.94
TRPM8 activation attenuates inflammatory responses in mouse models of colitis. Proc Natl Acad Sci U S A (2013) 0.94
Regulation of TRPM8 channel activity. Mol Cell Endocrinol (2011) 0.94
TRPM8 ion channels differentially modulate proliferation and cell cycle distribution of normal and cancer prostate cells. PLoS One (2012) 0.93
Modulation of thermoreceptor TRPM8 by cooling compounds. ACS Chem Neurosci (2012) 0.88
Pharmacological and functional properties of TRPM8 channels in prostate tumor cells. Pflugers Arch (2010) 0.88
Importance of placebo effect in cough clinical trials. Lung (2009) 0.88
Molecular mechanisms underlying Ca2+-mediated motility of human pancreatic duct cells. Am J Physiol Cell Physiol (2010) 0.88
Expression of TRPC6 in benign and malignant human prostate tissues. Asian J Androl (2009) 0.86
Pharmacology of transient receptor potential melastatin channels in the vasculature. Br J Pharmacol (2010) 0.85
TRP channel-associated factors are a novel protein family that regulates TRPM8 trafficking and activity. J Cell Biol (2015) 0.83
Contribution of the S5-pore-S6 domain to the gating characteristics of the cation channels TRPM2 and TRPM8. J Biol Chem (2010) 0.83
Trafficking of ThermoTRP Channels. Membranes (Basel) (2014) 0.83
Umbellulone modulates TRP channels. Pflugers Arch (2011) 0.83
Post-Translational Modifications of TRP Channels. Cells (2014) 0.81
Temperature and voltage coupling to channel opening in transient receptor potential melastatin 8 (TRPM8). J Biol Chem (2014) 0.80
Membrane potential measurements of isolated neurons using a voltage-sensitive dye. PLoS One (2013) 0.80
Functional expression of TRPM8 and TRPA1 channels in rat odontoblasts. PLoS One (2013) 0.79
TRPM8: a potential target for cancer treatment. J Cancer Res Clin Oncol (2016) 0.78
TRP Channels in Respiratory Pathophysiology: the Role of Oxidative, Chemical Irritant and Temperature Stimuli. Curr Neuropharmacol (2015) 0.78
Phospholipase C δ4 regulates cold sensitivity in mice. J Physiol (2016) 0.75
TRPM8 Channel Activation Induced by Monoterpenoid Rotundifolone Underlies Mesenteric Artery Relaxation. PLoS One (2015) 0.75
Cellular permeation of large molecules mediated by TRPM8 channels. Neurosci Lett (2016) 0.75
A novel TRPM8 agonist relieves dry eye discomfort. BMC Ophthalmol (2017) 0.75
The principle of temperature-dependent gating in cold- and heat-sensitive TRP channels. Nature (2004) 5.76
The TRP channels, a remarkably functional family. Cell (2002) 4.06
Activation of TRPV4 channels (hVRL-2/mTRP12) by phorbol derivatives. J Biol Chem (2002) 3.14
Impairment of store-operated Ca2+ entry in TRPC4(-/-) mice interferes with increase in lung microvascular permeability. Circ Res (2002) 3.05
A unified nomenclature for the superfamily of TRP cation channels. Mol Cell (2002) 2.99
Transient receptor potential M3 channels are ionotropic steroid receptors in pancreatic beta cells. Nat Cell Biol (2008) 2.71
TRPC3 channels are required for synaptic transmission and motor coordination. Neuron (2008) 2.30
Molecular determinants of permeation through the cation channel TRPV4. J Biol Chem (2002) 2.24
Voltage dependence of the Ca2+-activated cation channel TRPM4. J Biol Chem (2003) 2.21
Expression and role of TRPC proteins in human platelets: evidence that TRPC6 forms the store-independent calcium entry channel. Blood (2002) 2.16
Functional interactions among Orai1, TRPCs, and STIM1 suggest a STIM-regulated heteromeric Orai/TRPC model for SOCE/Icrac channels. Proc Natl Acad Sci U S A (2008) 2.11
Quantitative proteomics of the Cav2 channel nano-environments in the mammalian brain. Proc Natl Acad Sci U S A (2010) 1.85
Increased IgE-dependent mast cell activation and anaphylactic responses in mice lacking the calcium-activated nonselective cation channel TRPM4. Nat Immunol (2007) 1.68
TRPC3 mediates T-cell receptor-dependent calcium entry in human T-lymphocytes. J Biol Chem (2003) 1.53
Alternative splicing switches the divalent cation selectivity of TRPM3 channels. J Biol Chem (2005) 1.52
Isoform-specific inhibition of TRPC4 channel by phosphatidylinositol 4,5-bisphosphate. J Biol Chem (2008) 1.44
Murine ORAI2 splice variants form functional Ca2+ release-activated Ca2+ (CRAC) channels. J Biol Chem (2007) 1.42
De novo expression of Trpm4 initiates secondary hemorrhage in spinal cord injury. Nat Med (2009) 1.42
Expression of the Ca2+-selective cation channel TRPV6 in human prostate cancer: a novel prognostic marker for tumor progression. Oncogene (2003) 1.31
Deletion of TRPC4 and TRPC6 in mice impairs smooth muscle contraction and intestinal motility in vivo. Gastroenterology (2009) 1.31
Functional role of TRPC proteins in native systems: implications from knockout and knock-down studies. J Physiol (2005) 1.28
TRPC5 is a Ca2+-activated channel functionally coupled to Ca2+-selective ion channels. J Biol Chem (2009) 1.27
Trafficking and assembly of the cold-sensitive TRPM8 channel. J Biol Chem (2006) 1.26
Contribution of transient receptor potential channels to the control of GABA release from dendrites. Proc Natl Acad Sci U S A (2003) 1.25
Reduced cardiac L-type Ca2+ current in Ca(V)beta2-/- embryos impairs cardiac development and contraction with secondary defects in vascular maturation. Circ Res (2006) 1.24
L-type CaV1.2 calcium channels: from in vitro findings to in vivo function. Physiol Rev (2014) 1.23
Removal of Ca2+ channel beta3 subunit enhances Ca2+ oscillation frequency and insulin exocytosis. Cell (2004) 1.22
Ca2+-selective transient receptor potential V channel architecture and function require a specific ankyrin repeat. J Biol Chem (2004) 1.17
TRPC3 and TRPC6 are essential for normal mechanotransduction in subsets of sensory neurons and cochlear hair cells. Open Biol (2012) 1.16
TRPM4 cation channel mediates axonal and neuronal degeneration in experimental autoimmune encephalomyelitis and multiple sclerosis. Nat Med (2012) 1.11
Critical role for the beta regulatory subunits of Cav channels in T lymphocyte function. Proc Natl Acad Sci U S A (2006) 1.11
Pain perception in mice lacking the beta3 subunit of voltage-activated calcium channels. J Biol Chem (2002) 1.07
Increased catecholamine secretion contributes to hypertension in TRPM4-deficient mice. J Clin Invest (2010) 1.07
Ca2+ entry via TRPC channels is necessary for thrombin-induced NF-kappaB activation in endothelial cells through AMP-activated protein kinase and protein kinase Cdelta. J Biol Chem (2008) 1.07
TRPV6 and prostate cancer: cancer growth beyond the prostate correlates with increased TRPV6 Ca2+ channel expression. Biochem Biophys Res Commun (2004) 1.05
Canonical transient receptor channel 5 (TRPC5) and TRPC1/4 contribute to seizure and excitotoxicity by distinct cellular mechanisms. Mol Pharmacol (2012) 1.03
Modified cardiovascular L-type channels in mice lacking the voltage-dependent Ca2+ channel beta3 subunit. J Biol Chem (2003) 1.03
Alternative splicing of a protein domain indispensable for function of transient receptor potential melastatin 3 (TRPM3) ion channels. J Biol Chem (2012) 1.02
TRPV6 potentiates calcium-dependent cell proliferation. Cell Calcium (2005) 1.01
Primary structure, chromosomal localization and expression in immune cells of the murine ORAI and STIM genes. Cell Calcium (2007) 1.01
Diversity and developmental expression of L-type calcium channel beta2 proteins and their influence on calcium current in murine heart. J Biol Chem (2009) 1.01
Heteromeric canonical transient receptor potential 1 and 4 channels play a critical role in epileptiform burst firing and seizure-induced neurodegeneration. Mol Pharmacol (2011) 1.00
The Ca(2+) sensor stromal interaction molecule 1 (STIM1) is necessary and sufficient for the store-operated Ca(2+) entry function of transient receptor potential canonical (TRPC) 1 and 4 channels in endothelial cells. Mol Pharmacol (2011) 1.00
Altered inactivation of Ca2+ current and Ca2+ release in mouse muscle fibers deficient in the DHP receptor gamma1 subunit. J Gen Physiol (2004) 1.00
Male fertility depends on Ca²+ absorption by TRPV6 in epididymal epithelia. Sci Signal (2011) 0.95
The TRPV6 gene, cDNA and protein. Cell Calcium (2003) 0.93
TRPM4 regulates migration of mast cells in mice. Cell Calcium (2008) 0.93
Defective survival of naive CD8+ T lymphocytes in the absence of the beta3 regulatory subunit of voltage-gated calcium channels. Nat Immunol (2009) 0.93
The recombinant human TRPV6 channel functions as Ca2+ sensor in human embryonic kidney and rat basophilic leukemia cells. J Biol Chem (2002) 0.93
The auxiliary subunit gamma 1 of the skeletal muscle L-type Ca2+ channel is an endogenous Ca2+ antagonist. Proc Natl Acad Sci U S A (2007) 0.92
TRP channels as new pharmacological targets. Naunyn Schmiedebergs Arch Pharmacol (2005) 0.90
TRPC4 and TRPC4-deficient mice. Novartis Found Symp (2004) 0.90
TRP channels as potential drug targets. Biol Cell (2004) 0.89
Transient receptor potential channels function as a coincidence signal detector mediating phosphatidylserine exposure. Sci Signal (2013) 0.89
What do we really know and what do we need to know: some controversies, perspectives, and surprises. Handb Exp Pharmacol (2014) 0.87
Increased β-adrenergic inotropy in ventricular myocardium from Trpm4-/- mice. Circ Res (2013) 0.87
Classical transient receptor potential channel 1 in hypoxia-induced pulmonary hypertension. Am J Respir Crit Care Med (2013) 0.87
Ca2+ dependence of the Ca2+-selective TRPV6 channel. J Biol Chem (2004) 0.86
Lung endothelial Ca2+ and permeability response to platelet-activating factor is mediated by acid sphingomyelinase and transient receptor potential classical 6. Am J Respir Crit Care Med (2012) 0.86
Skeletal muscle L-type Ca(2+) current modulation in gamma1-deficient and wildtype murine myotubes by the gamma1 subunit and cAMP. J Physiol (2002) 0.84
Properties of the intracellular transient receptor potential (TRP) channel in yeast, Yvc1. FEBS Lett (2009) 0.83
Store-operated Ca2+ current and TRPV6 channels in lymph node prostate cancer cells. J Biol Chem (2003) 0.83
The transient receptor potential channel TRPV6 is dynamically expressed in bone cells but is not crucial for bone mineralization in mice. J Cell Physiol (2012) 0.83
Dual depolarization responses generated within the same lateral septal neurons by TRPC4-containing channels. Pflugers Arch (2014) 0.82
Conserved gating elements in TRPC4 and TRPC5 channels. J Biol Chem (2013) 0.82
Moderate calcium channel dysfunction in adult mice with inducible cardiomyocyte-specific excision of the cacnb2 gene. J Biol Chem (2011) 0.81
Mammalian transient receptor potential (TRP) cation channels. Preface. Handb Exp Pharmacol (2014) 0.81
Differential neuronal targeting of a new and two known calcium channel β4 subunit splice variants correlates with their regulation of gene expression. J Neurosci (2014) 0.81
The role of cGMP/cGKI signalling and Trpc channels in regulation of vascular tone. Cardiovasc Res (2013) 0.81
Transcriptional regulation and processing increase the functional variability of TRPM channels. Naunyn Schmiedebergs Arch Pharmacol (2005) 0.81
Functional TRPV6 channels are crucial for transepithelial Ca2+ absorption. Am J Physiol Gastrointest Liver Physiol (2012) 0.80
Membrane potential measurements of isolated neurons using a voltage-sensitive dye. PLoS One (2013) 0.80
Ba2+ currents in inner and outer hair cells of mice lacking the voltage-dependent Ca2+ channel subunits beta3 or beta4. Channels (Austin) (2009) 0.80
Ca2+ channel currents and contraction in CaVbeta3-deficient ileum smooth muscle from mouse. Cell Calcium (2007) 0.80
Excision of Trpv6 gene leads to severe defects in epididymal Ca2+ absorption and male fertility much like single D541A pore mutation. J Biol Chem (2012) 0.79
TRPV6 alleles do not influence prostate cancer progression. BMC Cancer (2009) 0.78
Voltage-dependent changes of TRPV6-mediated Ca2+ currents. J Biol Chem (2004) 0.78
The human TRPV6 channel protein is associated with cyclophilin B in human placenta. J Biol Chem (2008) 0.78
The Ca(2+)-activated cation channel TRPM4 is a negative regulator of angiotensin II-induced cardiac hypertrophy. Basic Res Cardiol (2015) 0.78
The in vivo TRPV6 protein starts at a non-AUG triplet, decoded as methionine, upstream of canonical initiation at AUG. J Biol Chem (2013) 0.77
TRPV6 channels. Handb Exp Pharmacol (2014) 0.76
Emerging Alternative Functions for the Auxiliary Subunits of the Voltage- Gated Calcium Channels. Curr Mol Pharmacol (2015) 0.75
Trans-activation response (TAR) RNA-binding protein 2 is a novel modulator of transient receptor potential canonical 4 (TRPC4) protein. J Biol Chem (2014) 0.75
The transient receptor potential cation channel subfamily V member 6 (TRPV6): genetics, biochemical properties, and functions of exceptional calcium channel proteins. Biochem Cell Biol (2014) 0.75