Published in Virology on June 06, 2007
A weighted average difference method for detecting differentially expressed genes from microarray data. Algorithms Mol Biol (2008) 1.27
Role for tumor necrosis factor-α in JC virus reactivation and progressive multifocal leukoencephalopathy. J Neuroimmunol (2010) 1.10
Polyomavirus JC infection inhibits differentiation of oligodendrocyte progenitor cells. J Neurosci Res (2012) 0.87
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Progressive multifocal leukoencephalopathy in a patient treated with natalizumab. N Engl J Med (2005) 7.04
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Establishment of a line of human fetal glial cells that supports JC virus multiplication. Proc Natl Acad Sci U S A (1985) 2.93
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JC virus infection of hematopoietic progenitor cells, primary B lymphocytes, and tonsillar stromal cells: implications for viral latency. J Virol (1996) 2.60
Detection of JC virus DNA in human tonsil tissue: evidence for site of initial viral infection. J Virol (1998) 2.43
JC virus enhancer-promoter active in human brain cells. Science (1984) 2.36
Nuclear accumulation of NFAT4 opposed by the JNK signal transduction pathway. Science (1997) 2.25
JC virus detection by in situ hybridization in brain tissue from elderly patients. Ann Neurol (1991) 2.09
JC virus DNA is present in many human brain samples from patients without progressive multifocal leukoencephalopathy. J Virol (1992) 1.84
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JC virus DNA sequences are frequently present in the human upper and lower gastrointestinal tract. Gastroenterology (2000) 1.68
Expression of cytokines in brain lesions in subacute sclerosing panencephalitis. Neurology (1994) 1.53
Evidence of human polyomavirus BK and JC infection in normal brain tissue. Virology (1992) 1.52
Extension of JC virus host range to monkey cells by insertion of a simian virus 40 enhancer into the JC virus regulatory region. Virology (1989) 1.41
Adjacent nuclear factor-1 and activator protein binding sites in the enhancer of the neurotropic JC virus. A common characteristic of many brain-specific genes. J Biol Chem (1992) 1.24
Nuclear factors in human brain cells bind specifically to the JCV regulatory region. EMBO J (1988) 1.23
Latency and reactivation of JC virus in peripheral blood of human immunodeficiency virus type 1-infected patients. J Clin Microbiol (1997) 1.14
Evaluation of the role of cytokine activation in the multiplication of JC virus (JCV) in human fetal glial cells. J Neurovirol (1995) 1.12
HIV-1 Nef interacts with inositol trisphosphate receptor to activate calcium signaling in T cells. J Exp Med (2002) 1.08
Progressive multifocal leukoencephalopathy in the United States, 1979-1994: increased mortality associated with HIV infection. Neuroepidemiology (1998) 1.07
Epidemiology and prognosis of AIDS-associated progressive multifocal leukoencephalopathy in the HAART era. J Neurovirol (2001) 1.07
JC virus binds to primary human glial cells, tonsillar stromal cells, and B-lymphocytes, but not to T lymphocytes. J Neurovirol (2000) 1.06
Propagation and assay of the JC virus. Methods Mol Biol (2001) 1.05
Broad distribution of the JC virus receptor contrasts with a marked cellular restriction of virus replication. Virology (2001) 1.05
Construction of a novel JCV/SV40 hybrid virus (JCSV) reveals a role for the JCV capsid in viral tropism. Virology (2002) 1.00
NFAT4 is required for JC virus infection of glial cells. J Virol (2006) 0.99
Detection of JC virus by polymerase chain reaction in cerebrospinal fluid from two patients with progressive multifocal leukoencephalopathy. Eur J Clin Microbiol Infect Dis (1992) 0.95
Human immunodeficiency virus type-1 tat enhances interleukin-2 promoter activity through synergism with phorbol ester and calcium-mediated activation of the NF-AT cis-regulatory motif. Biochem Biophys Res Commun (1994) 0.90
Derivation of a JC virus-resistant human glial cell line: implications for the identification of host cell factors that determine viral tropism. Virology (2003) 0.90
NFAT transcription factors control HIV-1 expression through a binding site downstream of TAR region. Immunobiology (2003) 0.90
JC virus and simian virus 40 enhancers and transforming proteins: role in determining tissue specificity and pathogenicity in transgenic mice. J Virol (1992) 0.89
Molecular biology and immunoregulation of human neurotropic JC virus in CNS. J Cell Physiol (2002) 0.88
Transcriptional activation of JC virus by human T-lymphotropic virus type I Tax protein in human neuronal cell lines. J Biol Chem (2000) 0.88
Regulation of T cell activation by HIV-1 accessory proteins: Vpr acts via distinct mechanisms to cooperate with Nef in NFAT-directed gene expression and to promote transactivation by CREB. Virology (2003) 0.88
Progressive multifocal leukoencephalopathy: improved survival of human immunodeficiency virus-infected patients in the protease inhibitor era. J Infect Dis (1999) 0.87
Macrophage chemoattractant protein-1 levels in cerebrospinal fluid correlate with containment of JC virus and prognosis of acquired immunodeficiency syndrome--associated progressive multifocal leukoencephalopathy. J Neurovirol (2005) 0.85
VP1 DNA sequences of JC and BK viruses detected in urine of systemic lupus erythematosus patients reveal no differences from strains expressed in normal individuals. J Gen Virol (2000) 0.85
NFAT4 is expressed in primary astrocytes and activated by glutamate. J Neurosci Res (2003) 0.85
Antibody response to human papovavirus JC (JCV) and simian virus 40 (SV40) T antigens in SV40 T antigen-transgenic mice. Virology (1992) 0.82
Is JC virus latent in brain? Ann Neurol (1991) 0.80
Telomere shortening triggers senescence of human cells through a pathway involving ATM, p53, and p21(CIP1), but not p16(INK4a). Mol Cell (2004) 6.48
Cellular senescence in aging primates. Science (2006) 6.24
The human polyomavirus, JCV, uses serotonin receptors to infect cells. Science (2004) 3.54
Accumulation of senescent cells in mitotic tissue of aging primates. Mech Ageing Dev (2006) 3.14
Molecular biology, epidemiology, and pathogenesis of progressive multifocal leukoencephalopathy, the JC virus-induced demyelinating disease of the human brain. Clin Microbiol Rev (2012) 2.92
A large scale genetic analysis of c-Myc-regulated gene expression patterns. J Biol Chem (2003) 2.69
A functional screen for Myc-responsive genes reveals serine hydroxymethyltransferase, a major source of the one-carbon unit for cell metabolism. Mol Cell Biol (2002) 2.27
Global regulation of nucleotide biosynthetic genes by c-Myc. PLoS One (2008) 2.12
The oncogene c-Myc coordinates regulation of metabolic networks to enable rapid cell cycle entry. Cell Cycle (2008) 2.09
Reduced c-Myc signaling triggers telomere-independent senescence by regulating Bmi-1 and p16(INK4a). Proc Natl Acad Sci U S A (2006) 2.06
Taxonomical developments in the family Polyomaviridae. Arch Virol (2011) 2.03
Cellular senescence and organismal aging. Mech Ageing Dev (2008) 1.92
Genome-scale expression profiling of Hutchinson-Gilford progeria syndrome reveals widespread transcriptional misregulation leading to mesodermal/mesenchymal defects and accelerated atherosclerosis. Aging Cell (2004) 1.87
Targeted inactivation of p53 in human cells does not result in aneuploidy. Cancer Res (2002) 1.86
Proteomic profiling of Myc-associated proteins. Cell Cycle (2010) 1.80
Infection of vero cells by BK virus is dependent on caveolae. J Virol (2004) 1.77
Direct correlation between sialic acid binding and infection of cells by two human polyomaviruses (JC virus and BK virus). J Virol (2007) 1.64
Genomes of replicatively senescent cells undergo global epigenetic changes leading to gene silencing and activation of transposable elements. Aging Cell (2013) 1.62
RKIP sensitizes prostate and breast cancer cells to drug-induced apoptosis. J Biol Chem (2004) 1.61
Structure-function analysis of the human JC polyomavirus establishes the LSTc pentasaccharide as a functional receptor motif. Cell Host Microbe (2010) 1.60
Loss of Raf kinase inhibitor protein promotes cell proliferation and migration of human hepatoma cells. Gastroenterology (2006) 1.49
Genome-wide siRNA screen identifies the retromer as a cellular entry factor for human papillomavirus. Proc Natl Acad Sci U S A (2013) 1.47
Stress response gene ATF3 is a target of c-myc in serum-induced cell proliferation. EMBO J (2005) 1.41
Contrasting roles of endosomal pH and the cytoskeleton in infection of human glial cells by JC virus and simian virus 40. J Virol (2003) 1.36
Loss of protooncogene c-Myc function impedes G1 phase progression both before and after the restriction point. Mol Biol Cell (2003) 1.34
Age-associated increase in heterochromatic marks in murine and primate tissues. Aging Cell (2010) 1.33
Abolition of cyclin-dependent kinase inhibitor p16Ink4a and p21Cip1/Waf1 functions permits Ras-induced anchorage-independent growth in telomerase-immortalized human fibroblasts. Mol Cell Biol (2003) 1.32
JC virus: an oncogenic virus in animals and humans? Semin Cancer Biol (2009) 1.28
Involvement of the INK4a/Arf gene locus in senescence. Aging Cell (2003) 1.28
Involvement of cytoskeletal components in BK virus infectious entry. J Virol (2005) 1.27
Formation of higher-order nuclear Rad51 structures is functionally linked to p21 expression and protection from DNA damage-induced apoptosis. J Cell Sci (2002) 1.26
Transposable elements become active and mobile in the genomes of aging mammalian somatic tissues. Aging (Albany NY) (2013) 1.26
Oligosaccharides as receptors for JC virus. J Virol (2002) 1.25
Regulation of growth arrest in senescence: telomere damage is not the end of the story. Mech Ageing Dev (2005) 1.25
The number of p16INK4a positive cells in human skin reflects biological age. Aging Cell (2012) 1.23
A JC virus-induced signal is required for infection of glial cells by a clathrin- and eps15-dependent pathway. J Virol (2004) 1.20
Molecular characterization of human telomerase reverse transcriptase-immortalized human fibroblasts by gene expression profiling: activation of the epiregulin gene. Cancer Res (2003) 1.18
BiP and multiple DNAJ molecular chaperones in the endoplasmic reticulum are required for efficient simian virus 40 infection. MBio (2011) 1.16
An N-linked glycoprotein with alpha(2,3)-linked sialic acid is a receptor for BK virus. J Virol (2005) 1.15
The Polyomaviridae: Contributions of virus structure to our understanding of virus receptors and infectious entry. Virology (2009) 1.15
Human alpha-defensins inhibit BK virus infection by aggregating virions and blocking binding to host cells. J Biol Chem (2008) 1.12
Analysis of cell cycle phases and progression in cultured mammalian cells. Methods (2007) 1.12
Differential distribution of the JC virus receptor-type sialic acid in normal human tissues. Am J Pathol (2004) 1.12
Loss of retinoblastoma but not p16 function allows bypass of replicative senescence in human fibroblasts. EMBO Rep (2003) 1.10
A proposal to sequence genomes of unique interest for research on aging. J Gerontol A Biol Sci Med Sci (2007) 1.10
The proto-oncogene c-myc acts through the cyclin-dependent kinase (Cdk) inhibitor p27(Kip1) to facilitate the activation of Cdk4/6 and early G(1) phase progression. J Biol Chem (2002) 1.06
Telomerase expression in normal human fibroblasts stabilizes DNA 5-methylcytosine transferase I. J Biol Chem (2003) 1.06
Signaling crossroads: the function of Raf kinase inhibitory protein in cancer, the central nervous system and reproduction. Cell Signal (2007) 1.04
Identification of amino acid residues in BK virus VP1 that are critical for viability and growth. J Virol (2007) 1.04
Modeling a sialic acid binding pocket in the external loops of JC virus VP1. J Biol Chem (2004) 1.03
A structure-guided mutation in the major capsid protein retargets BK polyomavirus. PLoS Pathog (2013) 1.02
Epigenetic control of aging. Antioxid Redox Signal (2010) 1.02
Transcriptional landscape of repetitive elements in normal and cancer human cells. BMC Genomics (2014) 1.01
Reconstructing networks of pathways via significance analysis of their intersections. BMC Bioinformatics (2008) 1.01
Construction of a novel JCV/SV40 hybrid virus (JCSV) reveals a role for the JCV capsid in viral tropism. Virology (2002) 1.00
The VP1 subunit of JC polyomavirus recapitulates early events in viral trafficking and is a novel tool to study polyomavirus entry. Virology (2012) 1.00
A retrograde trafficking inhibitor of ricin and Shiga-like toxins inhibits infection of cells by human and monkey polyomaviruses. MBio (2013) 1.00
Nuclear protein accumulation in cellular senescence and organismal aging revealed with a novel single-cell resolution fluorescence microscopy assay. Aging (Albany NY) (2011) 0.99
A link between the accumulation of DNA damage and loss of multi-potency of human mesenchymal stromal cells. J Cell Mol Med (2010) 0.99
NFAT4 is required for JC virus infection of glial cells. J Virol (2006) 0.99
A comparison of oncogene-induced senescence and replicative senescence: implications for tumor suppression and aging. Age (Dordr) (2014) 0.98
Raf kinase inhibitory protein knockout mice: expression in the brain and olfaction deficit. Brain Res Bull (2006) 0.97
Progressive multifocal leukoencephalopathy-associated mutations in the JC polyomavirus capsid disrupt lactoseries tetrasaccharide c binding. MBio (2013) 0.95
The structure of avian polyomavirus reveals variably sized capsids, non-conserved inter-capsomere interactions, and a possible location of the minor capsid protein VP4. Virology (2011) 0.92
Early events in the life cycle of JC virus as potential therapeutic targets for the treatment of progressive multifocal leukoencephalopathy. J Neurovirol (2003) 0.91
Derivation of a JC virus-resistant human glial cell line: implications for the identification of host cell factors that determine viral tropism. Virology (2003) 0.90
Role of N-linked glycosylation of the 5-HT2A receptor in JC virus infection. J Virol (2010) 0.90
5-HT2 receptors facilitate JC polyomavirus entry. J Virol (2013) 0.89
The RKIP (Raf-1 Kinase Inhibitor Protein) conserved pocket binds to the phosphorylated N-region of Raf-1 and inhibits the Raf-1-mediated activated phosphorylation of MEK. Cell Signal (2008) 0.89
c-Myc localization within the nucleus: evidence for association with the PML nuclear body. J Cell Biochem (2004) 0.89
Mice lacking Raf kinase inhibitor protein-1 (RKIP-1) have altered sperm capacitation and reduced reproduction rates with a normal response to testicular injury. J Androl (2007) 0.88
Real-time imaging of transcriptional activation in live cells reveals rapid up-regulation of the cyclin-dependent kinase inhibitor gene CDKN1A in replicative cellular senescence. Aging Cell (2003) 0.88
Engineering the serine/threonine protein kinase Raf-1 to utilise an orthogonal analogue of ATP substituted at the N6 position. FEBS Lett (2004) 0.88
How to measure RNA expression in rare senescent cells expressing any specific protein such as p16Ink4a. Aging (Albany NY) (2013) 0.86
Cellular senescence, epigenetic switches and c-Myc. Cell Cycle (2006) 0.86
Random mutagenesis of PDZ(Omi) domain and selection of mutants that specifically bind the Myc proto-oncogene and induce apoptosis. Oncogene (2003) 0.86
The role of sialic acid in human polyomavirus infections. Glycoconj J (2006) 0.86
Disruption of Supv3L1 damages the skin and causes sarcopenia, loss of fat, and death. Mamm Genome (2009) 0.86
Nuclear entry mechanism of the human polyomavirus JC virus-like particle: role of importins and the nuclear pore complex. J Biol Chem (2004) 0.85
Modulation of PML protein expression regulates JCV infection. Virology (2009) 0.84
Transcriptional regulation of BK virus by nuclear factor of activated T cells. J Virol (2009) 0.84
The human alpha defensin HD5 neutralizes JC polyomavirus infection by reducing endoplasmic reticulum traffic and stabilizing the viral capsid. J Virol (2013) 0.84
Surprise ending. Nat Genet (2003) 0.84
Postnatal liver growth and regeneration are independent of c-myc in a mouse model of conditional hepatic c-myc deletion. BMC Physiol (2012) 0.83
Pseudovirus mimics cell entry and trafficking of the human polyomavirus JCPyV. Virus Res (2013) 0.83
High-throughput cell-based screen for chemicals that inhibit infection by simian virus 40 and human polyomaviruses. J Virol (2009) 0.82
The effects of aging on the expression of Wnt pathway genes in mouse tissues. Age (Dordr) (2014) 0.81
Virus receptors and tropism. Adv Exp Med Biol (2006) 0.81
Nuclear factor of activated T-cells (NFAT) plays a role in SV40 infection. Virology (2007) 0.81
Probing the depths of cellular senescence. J Cell Biol (2013) 0.81