Published in Aging (Albany NY) on October 01, 2011
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Molecular characterization of human telomerase reverse transcriptase-immortalized human fibroblasts by gene expression profiling: activation of the epiregulin gene. Cancer Res (2003) 1.18
Stochastic variation in telomere shortening rate causes heterogeneity of human fibroblast replicative life span. J Biol Chem (2004) 1.13
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Loss of retinoblastoma but not p16 function allows bypass of replicative senescence in human fibroblasts. EMBO Rep (2003) 1.10
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A splice variant of stress response gene ATF3 counteracts NF-kappaB-dependent anti-apoptosis through inhibiting recruitment of CREB-binding protein/p300 coactivator. J Biol Chem (2005) 1.08
The proto-oncogene c-myc acts through the cyclin-dependent kinase (Cdk) inhibitor p27(Kip1) to facilitate the activation of Cdk4/6 and early G(1) phase progression. J Biol Chem (2002) 1.06
Telomerase expression in normal human fibroblasts stabilizes DNA 5-methylcytosine transferase I. J Biol Chem (2003) 1.06
Signaling crossroads: the function of Raf kinase inhibitory protein in cancer, the central nervous system and reproduction. Cell Signal (2007) 1.04
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Transcriptional landscape of repetitive elements in normal and cancer human cells. BMC Genomics (2014) 1.01
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NFAT4 is required for JC virus infection of glial cells. J Virol (2006) 0.99
A link between the accumulation of DNA damage and loss of multi-potency of human mesenchymal stromal cells. J Cell Mol Med (2010) 0.99
A comparison of oncogene-induced senescence and replicative senescence: implications for tumor suppression and aging. Age (Dordr) (2014) 0.98
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Cyclin A-associated kinase activity is needed for paclitaxel sensitivity. Mol Cancer Ther (2005) 0.92
PDK1 regulates cell proliferation and cell cycle progression through control of cyclin D1 and p27Kip1 expression. J Biol Chem (2008) 0.92
E2FBP1/DRIL1, an AT-rich interaction domain-family transcription factor, is regulated by p53. Mol Cancer Res (2003) 0.90
Systems analysis of ATF3 in stress response and cancer reveals opposing effects on pro-apoptotic genes in p53 pathway. PLoS One (2011) 0.90
The RKIP (Raf-1 Kinase Inhibitor Protein) conserved pocket binds to the phosphorylated N-region of Raf-1 and inhibits the Raf-1-mediated activated phosphorylation of MEK. Cell Signal (2008) 0.89
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Mice lacking Raf kinase inhibitor protein-1 (RKIP-1) have altered sperm capacitation and reduced reproduction rates with a normal response to testicular injury. J Androl (2007) 0.88
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Real-time imaging of transcriptional activation in live cells reveals rapid up-regulation of the cyclin-dependent kinase inhibitor gene CDKN1A in replicative cellular senescence. Aging Cell (2003) 0.88
Disruption of Supv3L1 damages the skin and causes sarcopenia, loss of fat, and death. Mamm Genome (2009) 0.86
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How to measure RNA expression in rare senescent cells expressing any specific protein such as p16Ink4a. Aging (Albany NY) (2013) 0.86
Cellular senescence, epigenetic switches and c-Myc. Cell Cycle (2006) 0.86
HMG-CoA reductase inhibitor fluvastatin prevents angiotensin II-induced cardiac hypertrophy via Rho kinase and inhibition of cyclin D1. Life Sci (2006) 0.84
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Postnatal liver growth and regeneration are independent of c-myc in a mouse model of conditional hepatic c-myc deletion. BMC Physiol (2012) 0.83
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Probing the depths of cellular senescence. J Cell Biol (2013) 0.81
The effects of aging on the expression of Wnt pathway genes in mouse tissues. Age (Dordr) (2014) 0.81
Regulation of RKIP function by Helicobacter pylori in gastric cancer. PLoS One (2012) 0.80
Kinetic profiling of the c-Myc transcriptome and bioinformatic analysis of repressed gene promoters. Cell Cycle (2011) 0.80
Histone acetyltransferase Hbo1 destabilizes estrogen receptor α by ubiquitination and modulates proliferation of breast cancers. Cancer Sci (2013) 0.79
Skp2 promotes adipocyte differentiation via a p27Kip1-independent mechanism in primary mouse embryonic fibroblasts. Biochem Biophys Res Commun (2008) 0.79
Microarray analysis of glial cells resistant to JCV infection suggests a correlation between viral infection and inflammatory cytokine gene expression. Virology (2007) 0.79
Correlation analysis reveals the emergence of coherence in the gene expression dynamics following system perturbation. BMC Bioinformatics (2007) 0.77
Gene targeting comes to top-down drug screens. Trends Biotechnol (2002) 0.77
Widespread expression of the Supv3L1 mitochondrial RNA helicase in the mouse. Transgenic Res (2009) 0.76
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Negative regulation of parathyroid hormone-related protein expression by steroid hormones. Biochem Biophys Res Commun (2011) 0.75
Reproductive cloning conserves cellular senescence. Nat Cell Biol (2003) 0.75
Wild-type and specific mutant androgen receptor mediates transcription via 17β-estradiol in sex hormone-sensitive cancer cells. J Cell Physiol (2015) 0.75
Primary polydipsia, but not accumulated ceramide, causes lethal renal damage in saposin D-deficient mice. Am J Physiol Renal Physiol (2012) 0.75