PubRank

Unnur Thorsteinsdottir

Author PubWeight™ 789.52‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Meta-analysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes. Nat Genet 2008 35.06
2 Biological, clinical and population relevance of 95 loci for blood lipids. Nature 2010 28.21
3 Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index. Nat Genet 2010 23.08
4 Genetics of gene expression and its effect on disease. Nature 2008 21.35
5 Large recurrent microdeletions associated with schizophrenia. Nature 2008 20.25
6 Hundreds of variants clustered in genomic loci and biological pathways affect human height. Nature 2010 20.01
7 Genome-wide association study identifies a second prostate cancer susceptibility variant at 8q24. Nat Genet 2007 19.18
8 Variant of transcription factor 7-like 2 (TCF7L2) gene confers risk of type 2 diabetes. Nat Genet 2006 19.03
9 A common variant on chromosome 9p21 affects the risk of myocardial infarction. Science 2007 18.96
10 New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk. Nat Genet 2010 17.89
11 Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis. Nat Genet 2010 16.96
12 A common variant associated with prostate cancer in European and African populations. Nat Genet 2006 13.47
13 A variant in CDKAL1 influences insulin response and risk of type 2 diabetes. Nat Genet 2007 13.28
14 Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease. Nat Genet 2011 13.25
15 Many sequence variants affecting diversity of adult human height. Nat Genet 2008 12.80
16 Two variants on chromosome 17 confer prostate cancer risk, and the one in TCF2 protects against type 2 diabetes. Nat Genet 2007 12.65
17 Genome-wide association yields new sequence variants at seven loci that associate with measures of obesity. Nat Genet 2008 12.43
18 Genome-wide association of early-onset myocardial infarction with single nucleotide polymorphisms and copy number variants. Nat Genet 2009 12.19
19 Plasma HDL cholesterol and risk of myocardial infarction: a mendelian randomisation study. Lancet 2012 12.10
20 Rate of de novo mutations and the importance of father's age to disease risk. Nature 2012 11.92
21 Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes. Nat Genet 2012 11.09
22 Variants in MTNR1B influence fasting glucose levels. Nat Genet 2008 10.85
23 Common variants on chromosomes 2q35 and 16q12 confer susceptibility to estrogen receptor-positive breast cancer. Nat Genet 2007 10.81
24 Common variants conferring risk of schizophrenia. Nature 2009 10.37
25 Variant of TREM2 associated with the risk of Alzheimer's disease. N Engl J Med 2012 10.16
26 Detection of sharing by descent, long-range phasing and haplotype imputation. Nat Genet 2008 9.69
27 Genetic determinants of hair, eye and skin pigmentation in Europeans. Nat Genet 2007 8.79
28 A mutation in APP protects against Alzheimer's disease and age-related cognitive decline. Nature 2012 8.10
29 Variants conferring risk of atrial fibrillation on chromosome 4q25. Nature 2007 8.03
30 Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution. Nat Genet 2010 7.94
31 Common variants on chromosome 5p12 confer susceptibility to estrogen receptor-positive breast cancer. Nat Genet 2008 7.65
32 Large-scale association analysis identifies new risk loci for coronary artery disease. Nat Genet 2012 7.59
33 Common sequence variants in the LOXL1 gene confer susceptibility to exfoliation glaucoma. Science 2007 7.55
34 Parental origin of sequence variants associated with complex diseases. Nature 2009 7.21
35 Sequence variants at the TERT-CLPTM1L locus associate with many cancer types. Nat Genet 2009 6.91
36 Sequence variants affecting eosinophil numbers associate with asthma and myocardial infarction. Nat Genet 2009 6.83
37 The same sequence variant on 9p21 associates with myocardial infarction, abdominal aortic aneurysm and intracranial aneurysm. Nat Genet 2008 6.72
38 Sequence variant on 8q24 confers susceptibility to urinary bladder cancer. Nat Genet 2008 6.69
39 Genetic variation in GIPR influences the glucose and insulin responses to an oral glucose challenge. Nat Genet 2010 6.66
40 Sequence variants at CHRNB3-CHRNA6 and CYP2A6 affect smoking behavior. Nat Genet 2010 6.49
41 Multiple genetic loci for bone mineral density and fractures. N Engl J Med 2008 6.35
42 Common sequence variants on 2p15 and Xp11.22 confer susceptibility to prostate cancer. Nat Genet 2008 6.10
43 Refining the impact of TCF7L2 gene variants on type 2 diabetes and adaptive evolution. Nat Genet 2007 5.88
44 Genome-wide association scan meta-analysis identifies three Loci influencing adiposity and fat distribution. PLoS Genet 2009 5.81
45 A genetic risk factor for periodic limb movements in sleep. N Engl J Med 2007 5.77
46 Genome-wide meta-analysis identifies 56 bone mineral density loci and reveals 14 loci associated with risk of fracture. Nat Genet 2012 5.48
47 Twenty bone-mineral-density loci identified by large-scale meta-analysis of genome-wide association studies. Nat Genet 2009 5.32
48 The gene encoding 5-lipoxygenase activating protein confers risk of myocardial infarction and stroke. Nat Genet 2004 5.31
49 Genome-wide association and replication studies identify four variants associated with prostate cancer susceptibility. Nat Genet 2009 5.06
50 Fine-scale recombination rate differences between sexes, populations and individuals. Nature 2010 4.74
51 A variant of the gene encoding leukotriene A4 hydrolase confers ethnicity-specific risk of myocardial infarction. Nat Genet 2005 4.45
52 New common variants affecting susceptibility to basal cell carcinoma. Nat Genet 2009 4.15
53 Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility. Nat Genet 2014 4.13
54 A sequence variant in ZFHX3 on 16q22 associates with atrial fibrillation and ischemic stroke. Nat Genet 2009 4.11
55 Common variants at 10 genomic loci influence hemoglobin A₁(C) levels via glycemic and nonglycemic pathways. Diabetes 2010 4.07
56 A rare variant in MYH6 is associated with high risk of sick sinus syndrome. Nat Genet 2011 3.94
57 Genetic risk factors for ischaemic stroke and its subtypes (the METASTROKE collaboration): a meta-analysis of genome-wide association studies. Lancet Neurol 2012 3.93
58 ASIP and TYR pigmentation variants associate with cutaneous melanoma and basal cell carcinoma. Nat Genet 2008 3.90
59 Seven new loci associated with age-related macular degeneration. Nat Genet 2013 3.81
60 Risk variants for atrial fibrillation on chromosome 4q25 associate with ischemic stroke. Ann Neurol 2008 3.75
61 Common variants on 9q22.33 and 14q13.3 predispose to thyroid cancer in European populations. Nat Genet 2009 3.46
62 New sequence variants associated with bone mineral density. Nat Genet 2008 3.43
63 Genome-wide association study identifies a variant in HDAC9 associated with large vessel ischemic stroke. Nat Genet 2012 3.40
64 Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressure. Nat Genet 2011 3.40
65 Thirty new loci for age at menarche identified by a meta-analysis of genome-wide association studies. Nat Genet 2010 3.37
66 Several common variants modulate heart rate, PR interval and QRS duration. Nat Genet 2010 3.34
67 On the replication of genetic associations: timing can be everything! Am J Hum Genet 2008 3.32
68 Two newly identified genetic determinants of pigmentation in Europeans. Nat Genet 2008 3.31
69 Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture. Nat Genet 2013 3.25
70 Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals. PLoS Genet 2012 3.21
71 Genome-wide association study identifies loci influencing concentrations of liver enzymes in plasma. Nat Genet 2011 3.18
72 Mutations in BRIP1 confer high risk of ovarian cancer. Nat Genet 2011 3.06
73 Sequence variants in the RNF212 gene associate with genome-wide recombination rate. Science 2008 3.00
74 Common variants associated with plasma triglycerides and risk for coronary artery disease. Nat Genet 2013 2.92
75 Genetic correction of PSA values using sequence variants associated with PSA levels. Sci Transl Med 2010 2.83
76 Sex-stratified genome-wide association studies including 270,000 individuals show sexual dimorphism in genetic loci for anthropometric traits. PLoS Genet 2013 2.83
77 Collaborative meta-analysis: associations of 150 candidate genes with osteoporosis and osteoporotic fracture. Ann Intern Med 2009 2.80
78 Seventy-five genetic loci influencing the human red blood cell. Nature 2012 2.77
79 FTO genotype is associated with phenotypic variability of body mass index. Nature 2012 2.77
80 Genetic variation in the prostate stem cell antigen gene PSCA confers susceptibility to urinary bladder cancer. Nat Genet 2009 2.76
81 Common variants near CAV1 and CAV2 are associated with primary open-angle glaucoma. Nat Genet 2010 2.75
82 Genetic variation near IRS1 associates with reduced adiposity and an impaired metabolic profile. Nat Genet 2011 2.73
83 Cancer as a complex phenotype: pattern of cancer distribution within and beyond the nuclear family. PLoS Med 2004 2.67
84 Genome-wide association study identifies sequence variants on 6q21 associated with age at menarche. Nat Genet 2009 2.58
85 Association of JAG1 with bone mineral density and osteoporotic fractures: a genome-wide association study and follow-up replication studies. Am J Hum Genet 2010 2.57
86 A sequence variant at 4p16.3 confers susceptibility to urinary bladder cancer. Nat Genet 2010 2.56
87 Nonsense mutation in the LGR4 gene is associated with several human diseases and other traits. Nature 2013 2.55
88 Familial risk of lung carcinoma in the Icelandic population. JAMA 2004 2.50
89 Identification of low-frequency variants associated with gout and serum uric acid levels. Nat Genet 2011 2.48
90 A germline variant in the TP53 polyadenylation signal confers cancer susceptibility. Nat Genet 2011 2.43
91 The association of a SNP upstream of INSIG2 with body mass index is reproduced in several but not all cohorts. PLoS Genet 2007 2.35
92 Stratifying type 2 diabetes cases by BMI identifies genetic risk variants in LAMA1 and enrichment for risk variants in lean compared to obese cases. PLoS Genet 2012 2.34
93 Variant in the sequence of the LINGO1 gene confers risk of essential tremor. Nat Genet 2009 2.29
94 A study based on whole-genome sequencing yields a rare variant at 8q24 associated with prostate cancer. Nat Genet 2012 2.29
95 Genetically determined height and coronary artery disease. N Engl J Med 2015 2.24
96 Common variants at VRK2 and TCF4 conferring risk of schizophrenia. Hum Mol Genet 2011 2.21
97 Lack of association between the Trp719Arg polymorphism in kinesin-like protein-6 and coronary artery disease in 19 case-control studies. J Am Coll Cardiol 2010 2.17
98 Meta-analyses identify 13 loci associated with age at menopause and highlight DNA repair and immune pathways. Nat Genet 2012 2.12
99 Genome-wide association and genetic functional studies identify autism susceptibility candidate 2 gene (AUTS2) in the regulation of alcohol consumption. Proc Natl Acad Sci U S A 2011 2.01
100 Common variants near FRK/COL10A1 and VEGFA are associated with advanced age-related macular degeneration. Hum Mol Genet 2011 1.98
101 Male-pattern baldness susceptibility locus at 20p11. Nat Genet 2008 1.87
102 Common variants on 1p36 and 1q42 are associated with cutaneous basal cell carcinoma but not with melanoma or pigmentation traits. Nat Genet 2008 1.84
103 Common variants at 6p21.1 are associated with large artery atherosclerotic stroke. Nat Genet 2012 1.81
104 Discovery of common variants associated with low TSH levels and thyroid cancer risk. Nat Genet 2012 1.81
105 Genome-wide association study identifies a sequence variant within the DAB2IP gene conferring susceptibility to abdominal aortic aneurysm. Nat Genet 2010 1.79
106 Meta-analysis of genome-wide association studies confirms a susceptibility locus for knee osteoarthritis on chromosome 7q22. Ann Rheum Dis 2010 1.75
107 A sequence variant on 17q21 is associated with age at onset and severity of asthma. Eur J Hum Genet 2010 1.74
108 Ancestry-shift refinement mapping of the C6orf97-ESR1 breast cancer susceptibility locus. PLoS Genet 2010 1.74
109 Sequence variants in the CLDN14 gene associate with kidney stones and bone mineral density. Nat Genet 2009 1.73
110 Identification of heart rate-associated loci and their effects on cardiac conduction and rhythm disorders. Nat Genet 2013 1.72
111 A genome-wide association search for type 2 diabetes genes in African Americans. PLoS One 2012 1.72
112 The role of adiposity in cardiometabolic traits: a Mendelian randomization analysis. PLoS Med 2013 1.70
113 Geographic differences in genetic susceptibility to IgA nephropathy: GWAS replication study and geospatial risk analysis. PLoS Genet 2012 1.69
114 Genetic evidence that raised sex hormone binding globulin (SHBG) levels reduce the risk of type 2 diabetes. Hum Mol Genet 2009 1.61
115 Abdominal aortic aneurysm is associated with a variant in low-density lipoprotein receptor-related protein 1. Am J Hum Genet 2011 1.60
116 European genome-wide association study identifies SLC14A1 as a new urinary bladder cancer susceptibility gene. Hum Mol Genet 2011 1.58
117 Assessment of gene-by-sex interaction effect on bone mineral density. J Bone Miner Res 2012 1.58
118 Common genetic variants associated with open-angle glaucoma. Hum Mol Genet 2011 1.58
119 Association of variants at UMOD with chronic kidney disease and kidney stones-role of age and comorbid diseases. PLoS Genet 2010 1.57
120 The BARD1 Cys557Ser variant and breast cancer risk in Iceland. PLoS Med 2006 1.53
121 Shared genetic susceptibility to ischemic stroke and coronary artery disease: a genome-wide analysis of common variants. Stroke 2013 1.51
122 A genome-wide association study of early menopause and the combined impact of identified variants. Hum Mol Genet 2013 1.50
123 Genome-wide association analyses identify multiple loci associated with central corneal thickness and keratoconus. Nat Genet 2013 1.49
124 Variants in DENND1A are associated with polycystic ovary syndrome in women of European ancestry. J Clin Endocrinol Metab 2012 1.44
125 Novel aspects of the pathogenesis of aneurysms of the abdominal aorta in humans. Cardiovasc Res 2010 1.33
126 Ischemic stroke is associated with the ABO locus: the EuroCLOT study. Ann Neurol 2013 1.30
127 European bone mineral density loci are also associated with BMD in East-Asian populations. PLoS One 2010 1.29
128 Genome-wide meta-analysis for serum calcium identifies significantly associated SNPs near the calcium-sensing receptor (CASR) gene. PLoS Genet 2010 1.25
129 A rare nonsynonymous sequence variant in C3 is associated with high risk of age-related macular degeneration. Nat Genet 2013 1.23
130 Meta-analysis of the INSIG2 association with obesity including 74,345 individuals: does heterogeneity of estimates relate to study design? PLoS Genet 2009 1.18
131 Apolipoprotein(a) genetic sequence variants associated with systemic atherosclerosis and coronary atherosclerotic burden but not with venous thromboembolism. J Am Coll Cardiol 2012 1.14
132 Identification of a specific intronic PEAR1 gene variant associated with greater platelet aggregability and protein expression. Blood 2011 1.13
133 A sequence variant associated with sortilin-1 (SORT1) on 1p13.3 is independently associated with abdominal aortic aneurysm. Hum Mol Genet 2013 1.10
134 Genetic architecture of vitamin B12 and folate levels uncovered applying deeply sequenced large datasets. PLoS Genet 2013 1.04
135 Sequence variants at CYP1A1-CYP1A2 and AHR associate with coffee consumption. Hum Mol Genet 2011 1.03
136 Support for involvement of the AHI1 locus in schizophrenia. Eur J Hum Genet 2007 1.03
137 A variant in LDLR is associated with abdominal aortic aneurysm. Circ Cardiovasc Genet 2013 1.00
138 Assessment of osteoarthritis candidate genes in a meta-analysis of nine genome-wide association studies. Arthritis Rheumatol 2014 1.00
139 A common variant at 8q24.21 is associated with renal cell cancer. Nat Commun 2013 0.96
140 PDE4D and ALOX5AP genetic variants and risk for Ischemic Cerebrovascular Disease in Sweden. J Neurol Sci 2007 0.96
141 Genetic predisposition to higher blood pressure increases coronary artery disease risk. Hypertension 2013 0.95
142 Genome-wide significant association between a sequence variant at 15q15.2 and lung cancer risk. Cancer Res 2011 0.92
143 Germline sequence variants in TGM3 and RGS22 confer risk of basal cell carcinoma. Hum Mol Genet 2014 0.90
144 A genome-wide copy number association study of osteoporotic fractures points to the 6p25.1 locus. J Med Genet 2013 0.84
145 Loss of heterozygosity at the FHIT gene in different solid human tumours and its association with survival in colorectal cancer patients. Anticancer Res 2003 0.84
146 A drastic reduction in the life span of cystatin C L68Q carriers due to life-style changes during the last two centuries. PLoS Genet 2008 0.81
147 Interstitial deletions including chromosome 3 common eliminated region 1 (C3CER1) prevail in human solid tumors from 10 different tissues. Genes Chromosomes Cancer 2004 0.81
148 Corrigendum: Genetic variants associated with subjective well-being, depressive symptoms, and neuroticism identified through genome-wide analyses. Nat Genet 2016 0.81
149 Correction: The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study. PLoS Genet 2016 0.75
150 Erratum: A protein-truncating R179X variant in RNF186 confers protection against ulcerative colitis. Nat Commun 2016 0.75
151 Corrigendum: Whole-genome sequencing identifies rare genotypes in COMP and CHADL associated with high risk of hip osteoarthritis. Nat Genet 2017 0.75
152 Corrigendum: Rare coding variants and X-linked loci associated with age at menarche. Nat Commun 2015 0.75
153 Corrigendum: Genetic variants associated with subjective well-being, depressive symptoms, and neuroticism identified through genome-wide analyses. Nat Genet 2016 0.75