Top1- and Top2-mediated topological transitions at replication forks ensure fork progression and stability and prevent DNA damage checkpoint activation.

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Published in Genes Dev on August 01, 2007

Authors

Rodrigo Bermejo1, Ylli Doksani, Thelma Capra, Yuki-Mori Katou, Hirokazu Tanaka, Katsuhiko Shirahige, Marco Foiani

Author Affiliations

1: Fondazione Italiana per la Ricerca sul Cancro (FIRC), Institute of Molecular Oncology Foundation (IFOM-IEO Campus) and DSBB-Università degli Studi di Milano, 20139 Milan, Italy.

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