Published in Pediatrics on October 18, 2010
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Early goal-directed therapy in the treatment of severe sepsis and septic shock. N Engl J Med (2001) 51.99
Intensive insulin therapy in critically ill patients. N Engl J Med (2001) 40.00
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Intensive insulin therapy in the medical ICU. N Engl J Med (2006) 22.37
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Hydrocortisone therapy for patients with septic shock. N Engl J Med (2008) 15.85
Whole-body hypothermia for neonates with hypoxic-ischemic encephalopathy. N Engl J Med (2005) 13.96
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Selective head cooling with mild systemic hypothermia after neonatal encephalopathy: multicentre randomised trial. Lancet (2005) 11.41
Vasopressin versus norepinephrine infusion in patients with septic shock. N Engl J Med (2008) 11.00
Benefits and risks of tight glucose control in critically ill adults: a meta-analysis. JAMA (2008) 10.15
Comparison of dopamine and norepinephrine in the treatment of shock. N Engl J Med (2010) 8.58
Severe hypoglycemia in critically ill patients: risk factors and outcomes. Crit Care Med (2007) 7.90
The Surviving Sepsis Campaign: results of an international guideline-based performance improvement program targeting severe sepsis. Crit Care Med (2010) 6.69
Intensive insulin therapy for patients in paediatric intensive care: a prospective, randomised controlled study. Lancet (2009) 6.44
Effect of out-of-hospital pediatric endotracheal intubation on survival and neurological outcome: a controlled clinical trial. JAMA (2000) 6.41
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A comparison of vasopressin and epinephrine for out-of-hospital cardiopulmonary resuscitation. N Engl J Med (2004) 6.04
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Cardiopulmonary resuscitation by bystanders with chest compression only (SOS-KANTO): an observational study. Lancet (2007) 5.89
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Quality of cardiopulmonary resuscitation during out-of-hospital cardiac arrest. JAMA (2005) 5.82
Quality of cardiopulmonary resuscitation during in-hospital cardiac arrest. JAMA (2005) 5.66
Cardiopulmonary resuscitation by chest compression alone or with mouth-to-mouth ventilation. N Engl J Med (2000) 5.65
Amiodarone as compared with lidocaine for shock-resistant ventricular fibrillation. N Engl J Med (2002) 5.52
Rapid Response Teams: A Systematic Review and Meta-analysis. Arch Intern Med (2010) 5.35
Etomidate versus ketamine for rapid sequence intubation in acutely ill patients: a multicentre randomised controlled trial. Lancet (2009) 5.31
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Outcome of survivors of accidental deep hypothermia and circulatory arrest treated with extracorporeal blood warming. N Engl J Med (1997) 5.00
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Norepinephrine plus dobutamine versus epinephrine alone for management of septic shock: a randomised trial. Lancet (2007) 4.81
Comparison of three fluid solutions for resuscitation in dengue shock syndrome. N Engl J Med (2005) 4.47
Saline or albumin for fluid resuscitation in patients with traumatic brain injury. N Engl J Med (2007) 4.42
Implementation of a bundle of quality indicators for the early management of severe sepsis and septic shock is associated with decreased mortality. Crit Care Med (2007) 4.42
Vasopressin versus epinephrine for inhospital cardiac arrest: a randomised controlled trial. Lancet (2001) 4.31
Family presence during invasive procedures and resuscitation. Am J Nurs (2000) 4.25
Sudden death in young adults: a 25-year review of autopsies in military recruits. Ann Intern Med (2004) 4.18
Prevalence of long-QT syndrome gene variants in sudden infant death syndrome. Circulation (2007) 4.10
Out-of-hospital pediatric cardiac arrest: an epidemiologic review and assessment of current knowledge. Ann Emerg Med (2005) 3.79
Prospective randomized controlled multi-centre trial of cuffed or uncuffed endotracheal tubes in small children. Br J Anaesth (2009) 3.70
Prehospital hypertonic saline resuscitation of patients with hypotension and severe traumatic brain injury: a randomized controlled trial. JAMA (2004) 3.54
Early insulin therapy in very-low-birth-weight infants. N Engl J Med (2008) 3.51
Amiodarone for resuscitation after out-of-hospital cardiac arrest due to ventricular fibrillation. N Engl J Med (1999) 3.48
Sudden death in the young. Heart Rhythm (2005) 3.29
Improved neurological outcome with continuous chest compressions compared with 30:2 compressions-to-ventilations cardiopulmonary resuscitation in a realistic swine model of out-of-hospital cardiac arrest. Circulation (2007) 3.27
Cell damage in the brain: a speculative synthesis. J Cereb Blood Flow Metab (1981) 3.21
Stress doses of hydrocortisone reverse hyperdynamic septic shock: a prospective, randomized, double-blind, single-center study. Crit Care Med (1999) 3.20
Survival is similar after standard treatment and chest compression only in out-of-hospital bystander cardiopulmonary resuscitation. Circulation (2007) 3.15
Effect of a rapid response team on hospital-wide mortality and code rates outside the ICU in a Children's Hospital. JAMA (2007) 3.12
Low-dose hydrocortisone improves shock reversal and reduces cytokine levels in early hyperdynamic septic shock. Crit Care Med (2005) 3.09
Hypotensive resuscitation during active hemorrhage: impact on in-hospital mortality. J Trauma (2002) 3.08
Effectiveness of bystander-initiated cardiac-only resuscitation for patients with out-of-hospital cardiac arrest. Circulation (2007) 3.01
End-tidal carbon dioxide and outcome of out-of-hospital cardiac arrest. N Engl J Med (1997) 2.98
Chest compression rates during cardiopulmonary resuscitation are suboptimal: a prospective study during in-hospital cardiac arrest. Circulation (2005) 2.94
Increasing use of cardiopulmonary resuscitation during out-of-hospital ventricular fibrillation arrest: survival implications of guideline changes. Circulation (2006) 2.93
Postmortem molecular analysis of SCN5A defects in sudden infant death syndrome. JAMA (2001) 2.89
Cumulative epinephrine dose during cardiopulmonary resuscitation and neurologic outcome. Ann Intern Med (1998) 2.88
Multicenter cohort study of in-hospital pediatric cardiac arrest. Pediatr Crit Care Med (2009) 2.81
End-tidal carbon dioxide concentration during cardiopulmonary resuscitation. N Engl J Med (1988) 2.80
Reduction of paediatric in-patient cardiac arrest and death with a medical emergency team: preliminary results. Arch Dis Child (2005) 2.79
Interaction of vasopressin infusion, corticosteroid treatment, and mortality of septic shock. Crit Care Med (2009) 2.77
Resuscitation of newborn infants with 100% oxygen or air: a systematic review and meta-analysis. Lancet (2004) 2.74
Psychological effect of witnessed resuscitation on bereaved relatives. Lancet (1998) 2.73
Vasopressin and epinephrine vs. epinephrine alone in cardiopulmonary resuscitation. N Engl J Med (2008) 2.72
Efficacy and safety of milrinone in preventing low cardiac output syndrome in infants and children after corrective surgery for congenital heart disease. Circulation (2003) 2.67
Crystalloids vs. colloids in fluid resuscitation: a systematic review. Crit Care Med (1999) 2.67
Hyperventilation-induced hypotension during cardiopulmonary resuscitation. Circulation (2004) 2.50
Epidemiology and outcomes from out-of-hospital cardiac arrest in children: the Resuscitation Outcomes Consortium Epistry-Cardiac Arrest. Circulation (2009) 2.49
Colloids versus crystalloids for fluid resuscitation in critically ill patients. Cochrane Database Syst Rev (2007) 2.45
Sudden unexplained death: heritability and diagnostic yield of cardiological and genetic examination in surviving relatives. Circulation (2005) 2.42
Targeted mutational analysis of the RyR2-encoded cardiac ryanodine receptor in sudden unexplained death: a molecular autopsy of 49 medical examiner/coroner's cases. Mayo Clin Proc (2004) 2.40
ACCM/PALS haemodynamic support guidelines for paediatric septic shock: an outcomes comparison with and without monitoring central venous oxygen saturation. Intensive Care Med (2008) 2.40
No assisted ventilation cardiopulmonary resuscitation and 24-hour neurological outcomes in a porcine model of cardiac arrest. Crit Care Med (2010) 2.39
Intravenous drug administration during out-of-hospital cardiac arrest: a randomized trial. JAMA (2009) 2.39
Adverse hemodynamic effects of interrupting chest compressions for rescue breathing during cardiopulmonary resuscitation for ventricular fibrillation cardiac arrest. Circulation (2001) 2.36
Reversible myocardial dysfunction in survivors of out-of-hospital cardiac arrest. J Am Coll Cardiol (2002) 2.27
[Hemodynamic effects of levosimendan compared with dobutamine in patients with low cardiac output after cardiac surgery]. Rev Esp Cardiol (2006) 2.26
Cardiological assessment of first-degree relatives in sudden arrhythmic death syndrome. Lancet (2003) 2.25
Comparison of cuffed and uncuffed endotracheal tubes in young children during general anesthesia. Anesthesiology (1997) 2.24
Attitudes toward and beliefs about family presence: a survey of healthcare providers, patients' families, and patients. Am J Crit Care (2007) 2.19
A randomized clinical trial of high-dose epinephrine and norepinephrine vs standard-dose epinephrine in prehospital cardiac arrest. JAMA (1992) 2.18
A comparison of repeated high doses and repeated standard doses of epinephrine for cardiac arrest outside the hospital. European Epinephrine Study Group. N Engl J Med (1998) 2.18
Guidelines and adenosine dosing in supraventricular tachycardia. Arch Dis Child (2005) 2.17
First appropriate use of automated external defibrillator in an infant. Resuscitation (2005) 2.14
Intraosseous infusion: an alternative route of pediatric intravascular access. Ann Emerg Med (1985) 2.14
Extracorporeal membrane oxygenation rescue for cardiopulmonary resuscitation in pediatric patients. Crit Care Med (2008) 2.13
Survival outcomes after extracorporeal cardiopulmonary resuscitation instituted during active chest compressions following refractory in-hospital pediatric cardiac arrest. Pediatr Crit Care Med (2004) 2.11
A prospective, population-based study of the epidemiology and outcome of out-of-hospital pediatric cardiopulmonary arrest. Pediatrics (2004) 2.11
Evaluation of cuffed tracheal tube size predicted using the Khine formula in children. Paediatr Anaesth (2008) 2.09
A comparison of high-dose and standard-dose epinephrine in children with cardiac arrest. N Engl J Med (2004) 2.08
High-dose epinephrine in adult cardiac arrest. N Engl J Med (1992) 2.06
Implementation of a medical emergency team in a large pediatric teaching hospital prevents respiratory and cardiopulmonary arrests outside the intensive care unit. Pediatr Crit Care Med (2007) 2.06
The effect of cricoid pressure on preventing gastric insufflation in infants and children. Anesthesiology (1993) 2.05
Pediatric submersions: prehospital predictors of outcome. Pediatrics (1992) 2.05
Sodium bicarbonate improves outcome in prolonged prehospital cardiac arrest. Am J Emerg Med (2006) 2.05
Transfusion strategies for patients in pediatric intensive care units. N Engl J Med (2007) 7.21
Cardiopulmonary resuscitation of adults in the hospital: a report of 14720 cardiac arrests from the National Registry of Cardiopulmonary Resuscitation. Resuscitation (2003) 6.95
Duration of resuscitation efforts and survival after in-hospital cardiac arrest: an observational study. Lancet (2012) 6.60
Imaging studies after a first febrile urinary tract infection in young children. N Engl J Med (2003) 6.42
First documented rhythm and clinical outcome from in-hospital cardiac arrest among children and adults. JAMA (2006) 6.23
Survival from in-hospital cardiac arrest during nights and weekends. JAMA (2008) 6.03
Part 9: post-cardiac arrest care: 2010 American Heart Association Guidelines for Cardiopulmonary Resuscitation and Emergency Cardiovascular Care. Circulation (2010) 6.01
European Resuscitation Council Guidelines for Resuscitation 2010 Section 1. Executive summary. Resuscitation (2010) 5.58
Rapid Response Teams: A Systematic Review and Meta-analysis. Arch Intern Med (2010) 5.35
Therapeutic hypothermia after out-of-hospital cardiac arrest in children. N Engl J Med (2015) 4.90
Part 1: executive summary: 2010 American Heart Association Guidelines for Cardiopulmonary Resuscitation and Emergency Cardiovascular Care. Circulation (2010) 4.59
Duration of cardiopulmonary resuscitation and illness category impact survival and neurologic outcomes for in-hospital pediatric cardiac arrests. Circulation (2013) 4.46
Incidence of treated cardiac arrest in hospitalized patients in the United States. Crit Care Med (2011) 4.43
Chest compression-only CPR by lay rescuers and survival from out-of-hospital cardiac arrest. JAMA (2010) 4.35
Ventricular tachyarrhythmias after cardiac arrest in public versus at home. N Engl J Med (2011) 4.26
Part 5: adult basic life support: 2010 American Heart Association Guidelines for Cardiopulmonary Resuscitation and Emergency Cardiovascular Care. Circulation (2010) 4.16
Rationale, development and implementation of the Resuscitation Outcomes Consortium Epistry-Cardiac Arrest. Resuscitation (2008) 3.98
Global incidences of out-of-hospital cardiac arrest and survival rates: Systematic review of 67 prospective studies. Resuscitation (2010) 3.98
Out-of-hospital pediatric cardiac arrest: an epidemiologic review and assessment of current knowledge. Ann Emerg Med (2005) 3.79
Part 11: Neonatal resuscitation: 2010 International Consensus on Cardiopulmonary Resuscitation and Emergency Cardiovascular Care Science With Treatment Recommendations. Circulation (2010) 3.41
Automated external defibrillators and survival after in-hospital cardiac arrest. JAMA (2010) 3.36
Hospital-wide code rates and mortality before and after implementation of a rapid response team. JAMA (2008) 3.30
Improved neurological outcome with continuous chest compressions compared with 30:2 compressions-to-ventilations cardiopulmonary resuscitation in a realistic swine model of out-of-hospital cardiac arrest. Circulation (2007) 3.27
Part 14: pediatric advanced life support: 2010 American Heart Association Guidelines for Cardiopulmonary Resuscitation and Emergency Cardiovascular Care. Circulation (2010) 3.20
Rhythms and outcomes of adult in-hospital cardiac arrest. Crit Care Med (2010) 3.19
Effectiveness of bystander-initiated cardiac-only resuscitation for patients with out-of-hospital cardiac arrest. Circulation (2007) 3.01
Therapeutic hypothermia after cardiac arrest. An advisory statement by the Advancement Life support Task Force of the International Liaison committee on Resuscitation. Resuscitation (2003) 3.00
Neonatal resuscitation: 2010 American Heart Association Guidelines for Cardiopulmonary Resuscitation and Emergency Cardiovascular Care. Pediatrics (2010) 2.98
Minimally interrupted cardiac resuscitation by emergency medical services for out-of-hospital cardiac arrest. JAMA (2008) 2.91
Part 15: neonatal resuscitation: 2010 American Heart Association Guidelines for Cardiopulmonary Resuscitation and Emergency Cardiovascular Care. Circulation (2010) 2.85
Part 4: CPR overview: 2010 American Heart Association Guidelines for Cardiopulmonary Resuscitation and Emergency Cardiovascular Care. Circulation (2010) 2.82
Use of therapeutic hypothermia after in-hospital cardiac arrest. Crit Care Med (2013) 2.81
Use of impedance threshold device in conjunction with our novel adhesive glove device for ACD-CPR does not result in additional chest decompression. Resuscitation (2013) 2.62
Antivenom for critically ill children with neurotoxicity from scorpion stings. N Engl J Med (2009) 2.53
American Heart Association guidelines for primary prevention of atherosclerotic cardiovascular disease beginning in childhood. Circulation (2003) 2.51
Epidemiology and outcomes from out-of-hospital cardiac arrest in children: the Resuscitation Outcomes Consortium Epistry-Cardiac Arrest. Circulation (2009) 2.49
Cardiopulmonary resuscitation quality: [corrected] improving cardiac resuscitation outcomes both inside and outside the hospital: a consensus statement from the American Heart Association. Circulation (2013) 2.49
Exception from informed consent for pediatric resuscitation research: community consultation for a trial of brain cooling after in-hospital cardiac arrest. Pediatrics (2004) 2.41
Cytokine release syndrome after blinatumomab treatment related to abnormal macrophage activation and ameliorated with cytokine-directed therapy. Blood (2013) 2.39
Polymerase chain reaction for diagnosis of human immunodeficiency virus infection in infancy in low resource settings. Pediatr Infect Dis J (2005) 2.39
Time-dependent effectiveness of chest compression-only and conventional cardiopulmonary resuscitation for out-of-hospital cardiac arrest of cardiac origin. Resuscitation (2010) 2.38
Electrographic status epilepticus is associated with mortality and worse short-term outcome in critically ill children. Crit Care Med (2013) 2.36
Perishock pause: an independent predictor of survival from out-of-hospital shockable cardiac arrest. Circulation (2011) 2.31
Part 1: Executive summary: 2010 International Consensus on Cardiopulmonary Resuscitation and Emergency Cardiovascular Care Science With Treatment Recommendations. Circulation (2010) 2.31
Early postresuscitation hypotension is associated with increased mortality following pediatric cardiac arrest. Crit Care Med (2014) 2.26
Relationship between chest compression rates and outcomes from cardiac arrest. Circulation (2012) 2.25
Simultaneous Prediction of New Morbidity, Mortality, and Survival Without New Morbidity From Pediatric Intensive Care: A New Paradigm for Outcomes Assessment. Crit Care Med (2015) 2.24
Greater fluctuations in serum sodium levels are associated with increased mortality in children with externalized ventriculostomy drains in a PICU. Pediatr Crit Care Med (2014) 2.22
Backboards are important when chest compressions are provided on a soft mattress. Resuscitation (2012) 2.19
Neonatal resuscitation: 2010 International Consensus on Cardiopulmonary Resuscitation and Emergency Cardiovascular Care Science with Treatment Recommendations. Pediatrics (2010) 2.13
Education in resuscitation. Resuscitation (2003) 2.12
Survival outcomes after extracorporeal cardiopulmonary resuscitation instituted during active chest compressions following refractory in-hospital pediatric cardiac arrest. Pediatr Crit Care Med (2004) 2.11
Outcome prediction by motor and pupillary responses in children treated with therapeutic hypothermia after cardiac arrest. Pediatr Crit Care Med (2012) 2.09