Published in Antioxid Redox Signal on November 01, 2007
Free radicals, antioxidants in disease and health. Int J Biomed Sci (2008) 2.89
Transepithelial migration of neutrophils: mechanisms and implications for acute lung injury. Am J Respir Cell Mol Biol (2008) 1.93
Lipopolysaccharide-induced expression of NAD(P)H:quinone oxidoreductase 1 and heme oxygenase-1 protects against excessive inflammatory responses in human monocytes. J Immunol (2008) 1.57
The redox-sensitive cation channel TRPM2 modulates phagocyte ROS production and inflammation. Nat Immunol (2011) 1.55
Redox control of inflammation in macrophages. Antioxid Redox Signal (2013) 1.39
Effect of IL-10 on neutrophil recruitment and survival after Pseudomonas aeruginosa challenge. Am J Respir Cell Mol Biol (2008) 1.23
Disruption of Nrf2 enhances upregulation of nuclear factor-kappaB activity, proinflammatory cytokines, and intercellular adhesion molecule-1 in the brain after traumatic brain injury. Mediators Inflamm (2009) 1.22
β(2)-Adrenoreceptor blockade improves early posttrauma hyperglycemia and pulmonary injury in obese rats. Am J Physiol Heart Circ Physiol (2014) 1.16
Targeted detoxification of selected reactive oxygen species in the vascular endothelium. J Pharmacol Exp Ther (2009) 1.11
The crosstalk between Nrf2 and AMPK signal pathways is important for the anti-inflammatory effect of berberine in LPS-stimulated macrophages and endotoxin-shocked mice. Antioxid Redox Signal (2013) 1.09
Immuno-spin trapping of a post-translational carboxypeptidase B1 radical formed by a dual role of xanthine oxidase and endothelial nitric oxide synthase in acute septic mice. Free Radic Biol Med (2008) 1.08
Antioxidant components of naturally-occurring oils exhibit marked anti-inflammatory activity in epithelial cells of the human upper respiratory system. Respir Res (2011) 0.96
Protective effects of luteolin against lipopolysaccharide-induced acute lung injury involves inhibition of MEK/ERK and PI3K/Akt pathways in neutrophils. Acta Pharmacol Sin (2010) 0.95
Cross-talk between pulmonary injury, oxidant stress, and gap junctional communication. Antioxid Redox Signal (2009) 0.94
Isovitexin Exerts Anti-Inflammatory and Anti-Oxidant Activities on Lipopolysaccharide-Induced Acute Lung Injury by Inhibiting MAPK and NF-κB and Activating HO-1/Nrf2 Pathways. Int J Biol Sci (2016) 0.91
Activation of the liver X receptor prevents lipopolysaccharide-induced lung injury. J Biol Chem (2009) 0.90
Time profile of oxidative stress and neutrophil activation in ovine acute lung injury and sepsis. Shock (2012) 0.90
Therapeutic targeting of acute lung injury and acute respiratory distress syndrome. Transl Res (2015) 0.90
Phytochemical antioxidants modulate mammalian cellular epigenome: implications in health and disease. Antioxid Redox Signal (2012) 0.89
Neutrophil-mediated lung permeability and host defense proteins. Am J Physiol Lung Cell Mol Physiol (2009) 0.89
Inhibition of NADPH oxidase prevents acute lung injury in obese rats following severe trauma. Am J Physiol Heart Circ Physiol (2014) 0.88
Role of nicotinamide adenine dinucleotide phosphate-reduced oxidase proteins in Pseudomonas aeruginosa-induced lung inflammation and permeability. Am J Respir Cell Mol Biol (2013) 0.87
Does leflunomide attenuate the sepsis-induced acute lung injury? Pediatr Surg Int (2008) 0.87
Sepsis: redox mechanisms and therapeutic opportunities. Antioxid Redox Signal (2007) 0.87
Comparison of reducing effect on lung injury of dexamethasone and bosentan in acute lung injury: an experimental study. Multidiscip Respir Med (2013) 0.84
The down regulation of neutrophil oxidative metabolism by S100A8 and S100A9: implication of the protease-activated receptor-2. Mol Immunol (2011) 0.84
Female X-chromosome mosaicism for gp91phox expression diversifies leukocyte responses during endotoxemia. Crit Care Med (2010) 0.82
LIM kinase 1 promotes endothelial barrier disruption and neutrophil infiltration in mouse lungs. Circ Res (2009) 0.82
Pro-inflammatory endothelial cell dysfunction is associated with intersectin-1s down-regulation. Respir Res (2011) 0.81
Loss of caveolin-1 and adiponectin induces severe inflammatory lung injury following LPS challenge through excessive oxidative/nitrative stress. Am J Physiol Lung Cell Mol Physiol (2014) 0.80
NOX2 protects against progressive lung injury and multiple organ dysfunction syndrome. Am J Physiol Lung Cell Mol Physiol (2014) 0.80
ATF3 protects pulmonary resident cells from acute and ventilator-induced lung injury by preventing Nrf2 degradation. Antioxid Redox Signal (2015) 0.80
Trimetazidine prevents macrophage-mediated septic myocardial dysfunction via activation of the histone deacetylase sirtuin 1. Br J Pharmacol (2015) 0.80
Protective effect of gastrin-releasing peptide receptor antagonist in carrageenan-induced pleural inflammation in rats. Inflamm Res (2010) 0.79
Pathophysiological Approaches of Acute Respiratory Distress syndrome: Novel Bases for Study of Lung Injury. Open Respir Med J (2015) 0.79
"Crossroads in Sepsis Research" Review Series Overview of the pathophysiology of sepsis. J Cell Mol Med (2008) 0.79
Shuang-huang-lian attenuates lipopolysaccharide-induced acute lung injury in mice involving anti-inflammatory and antioxidative activities. Evid Based Complement Alternat Med (2015) 0.79
Oxidants in Acute and Chronic Lung Disease. J Blood Lymph (2015) 0.78
Febuxostat protects rats against lipopolysaccharide-induced lung inflammation in a dose-dependent manner. Naunyn Schmiedebergs Arch Pharmacol (2015) 0.78
Mitochondrial anti-oxidant protects IEX-1 deficient mice from organ damage during endotoxemia. Int Immunopharmacol (2014) 0.77
Reduced oxidative tissue damage during endotoxemia in IRAK-1 deficient mice. Mol Immunol (2012) 0.77
Tetrahydrocoptisine protects rats from LPS-induced acute lung injury. Inflammation (2014) 0.76
Role of transcriptional factor Nrf2 in the acute lung injury of mice. Int J Clin Exp Pathol (2015) 0.76
Combined effects of a neutrophil elastase inhibitor (sivelestat sodium) and a free radical scavenger (edaravone) on lipopolysaccharide-induced acute lung injury in rats. Inflamm Res (2012) 0.76
OBESITY AND CRITICAL ILLNESS: INSIGHTS FROM ANIMAL MODELS. Shock (2016) 0.76
CD11c+ cells are required to prevent progression from local acute lung injury to multiple organ failure and death. Am J Pathol (2009) 0.76
15-F2t -Isoprostane Concentrations and Oxidant Status in Lactating Dairy Cattle with Acute Coliform Mastitis. J Vet Intern Med (2015) 0.75
Lipopolysaccharide Cross-Tolerance Delays Platelet-Activating Factor-Induced Sudden Death in Swiss Albino Mice: Involvement of Cyclooxygenase in Cross-Tolerance. PLoS One (2016) 0.75
Identification of cardioprotective agents from traditional Chinese medicine against oxidative damage. Mol Med Rep (2016) 0.75
Insights into and relative effect of chitosan-H, chitosan-H-propolis, chitosan-H-propolis-nystatin and chitosan-H-nystatin on dentine bond strength. Eur J Dent (2013) 0.75
Value of caffeic acid phenethyl ester pretreatment in experimental sepsis model in rats. Mediators Inflamm (2015) 0.75
ExoU-induced redox imbalance and oxidative stress in airway epithelial cells during Pseudomonas aeruginosa pneumosepsis. Med Microbiol Immunol (2015) 0.75
Nicotinamide Adenine Dinucleotide Phosphate Oxidase 2 Regulates LPS-Induced Inflammation and Alveolar Remodeling in the Developing Lung. Am J Respir Cell Mol Biol (2016) 0.75
Effects of gamma oryzanol on factors of oxidative stress and sepsis-induced lung injury in experimental animal model. Iran J Basic Med Sci (2015) 0.75
Pediatric Respiratory Assembly. Mini symposium on lung inflammation. Can Respir J (2010) 0.75
Ebselen Attenuates Lung Injury in Experimental Model of Carrageenan-Induced Pleurisy in Rats. Inflammation (2015) 0.75
Oxidative Stress: Harms and Benefits for Human Health. Oxid Med Cell Longev (2017) 0.75
Immunodesign of experimental sepsis by cecal ligation and puncture. Nat Protoc (2009) 6.71
Harmful molecular mechanisms in sepsis. Nat Rev Immunol (2008) 6.03
Generation of C5a in the absence of C3: a new complement activation pathway. Nat Med (2006) 5.26
Novel strategies for the treatment of sepsis. Nat Med (2003) 5.14
The NLR gene family: a standard nomenclature. Immunity (2008) 4.77
Role of C5a in inflammatory responses. Annu Rev Immunol (2005) 4.38
The enigma of sepsis. J Clin Invest (2003) 4.32
Functional roles for C5a receptors in sepsis. Nat Med (2008) 3.33
The disconnect between animal models of sepsis and human sepsis. J Leukoc Biol (2006) 3.11
Adverse functions of IL-17A in experimental sepsis. FASEB J (2008) 2.60
Phagocyte-derived catecholamines enhance acute inflammatory injury. Nature (2007) 2.56
Protective effects of IL-6 blockade in sepsis are linked to reduced C5a receptor expression. J Immunol (2003) 2.00
The complement system. Cell Tissue Res (2010) 1.86
Increased C5a receptor expression in sepsis. J Clin Invest (2002) 1.79
Generation of C5a by phagocytic cells. Am J Pathol (2002) 1.72
Changes and regulation of the C5a receptor on neutrophils during septic shock in humans. J Immunol (2013) 1.57
Regulation by C5a of neutrophil activation during sepsis. Immunity (2003) 1.54
Evidence for a functional role of the second C5a receptor C5L2. FASEB J (2005) 1.53
Expression and function of C5a receptor in mouse microvascular endothelial cells. J Immunol (2002) 1.53
Role of nitric oxide in acute lung inflammation: lessons learned from the inducible nitric oxide synthase knockout mouse. Crit Care Med (2002) 1.51
Evaluation of endotoxin models for the study of sepsis. Shock (2005) 1.47
Interactions between coagulation and complement--their role in inflammation. Semin Immunopathol (2011) 1.46
Complement-induced impairment of innate immunity during sepsis. J Immunol (2002) 1.44
Protection of innate immunity by C5aR antagonist in septic mice. FASEB J (2002) 1.44
Novel chemokine responsiveness and mobilization of neutrophils during sepsis. Am J Pathol (2004) 1.42
Regulatory role of C5a in LPS-induced IL-6 production by neutrophils during sepsis. FASEB J (2003) 1.42
Regulatory effects of iNOS on acute lung inflammatory responses in mice. Am J Pathol (2003) 1.42
Harmful and protective roles of neutrophils in sepsis. Shock (2005) 1.41
Targeting of microRNA-142-3p in dendritic cells regulates endotoxin-induced mortality. Blood (2011) 1.39
C5 deficiency and C5a or C5aR blockade protects against cerebral malaria. J Exp Med (2008) 1.38
Humanizing the mouse: in defense of murine models of critical illness. Am J Respir Crit Care Med (2013) 1.36
Mediators and regulation of neutrophil accumulation in inflammatory responses in lung: insights from the IgG immune complex model. Free Radic Biol Med (2002) 1.35
The inflammatory response in sepsis. Trends Immunol (2012) 1.34
C5a-induced gene expression in human umbilical vein endothelial cells. Am J Pathol (2004) 1.34
Role of C3, C5 and anaphylatoxin receptors in acute lung injury and in sepsis. Adv Exp Med Biol (2012) 1.34
Anti-c5a ameliorates coagulation/fibrinolytic protein changes in a rat model of sepsis. Am J Pathol (2002) 1.33
Relationship of acute lung inflammatory injury to Fas/FasL system. Am J Pathol (2005) 1.33
Regulatory effects of estrogen on acute lung inflammation in mice. Am J Physiol Cell Physiol (2005) 1.32
C5a receptor and thymocyte apoptosis in sepsis. FASEB J (2002) 1.31
Anti-inflammatory effects of β2 adrenergic receptor agonists in experimental acute lung injury. FASEB J (2012) 1.31
Functions of the complement components C3 and C5 during sepsis. FASEB J (2008) 1.30
An essential role for complement C5a in the pathogenesis of septic cardiac dysfunction. J Exp Med (2005) 1.29
Extracellular histones are essential effectors of C5aR- and C5L2-mediated tissue damage and inflammation in acute lung injury. FASEB J (2013) 1.26
Inhibition of the alternative complement activation pathway in traumatic brain injury by a monoclonal anti-factor B antibody: a randomized placebo-controlled study in mice. J Neuroinflammation (2007) 1.24
Immunosuppression in sepsis. JAMA (2011) 1.22
Acute lung injury induced by lipopolysaccharide is independent of complement activation. J Immunol (2008) 1.22
Regulation of lung inflammation in the model of IgG immune-complex injury. Annu Rev Pathol (2006) 1.20
Inhibition of complement C5a prevents breakdown of the blood-brain barrier and pituitary dysfunction in experimental sepsis. Crit Care (2009) 1.20
Catecholamines-crafty weapons in the inflammatory arsenal of immune/inflammatory cells or opening pandora's box? Mol Med (2008) 1.20
Cross-talk between TLR4 and FcgammaReceptorIII (CD16) pathways. PLoS Pathog (2009) 1.20
Changes in the novel orphan, C5a receptor (C5L2), during experimental sepsis and sepsis in humans. J Immunol (2005) 1.19
Evidence for anti-inflammatory effects of C5a on the innate IL-17A/IL-23 axis. FASEB J (2011) 1.19
Stat3 activation in acute lung injury. J Immunol (2004) 1.18
Molecular events in the cardiomyopathy of sepsis. Mol Med (2008) 1.18
Ischemia/reperfusion injury. J Surg Res (2002) 1.16
Upregulation of phagocyte-derived catecholamines augments the acute inflammatory response. PLoS One (2009) 1.16
Complement in ischemia reperfusion injury. Am J Pathol (2003) 1.15
Expression and function of the C5a receptor in rat alveolar epithelial cells. J Immunol (2002) 1.14
Murine complement interactions with Pseudomonas aeruginosa and their consequences during pneumonia. Am J Respir Cell Mol Biol (2003) 1.14
Opportunities and challenges of disease biomarkers: a new section in the Journal of Translational Medicine. J Transl Med (2012) 1.13
In vivo regulation of neutrophil apoptosis by C5a during sepsis. J Leukoc Biol (2006) 1.12
Altered neutrophil trafficking during sepsis. J Immunol (2002) 1.11
Role of endothelial chemokines and their receptors during inflammation. J Invest Surg (2011) 1.11
Attenuation of half sulfur mustard gas-induced acute lung injury in rats. J Appl Toxicol (2006) 1.10
Reduced neuronal cell death after experimental brain injury in mice lacking a functional alternative pathway of complement activation. BMC Neurosci (2006) 1.09
Retracted Opportunities and challenges of disease biomarkers: a new section in the Journal of Translational Medicine. J Transl Med (2012) 1.08
Protection from half-mustard-gas-induced acute lung injury in the rat. J Appl Toxicol (2002) 1.08
Neutrophil C5a receptor and the outcome in a rat model of sepsis. FASEB J (2003) 1.08
Role of C5a-C5aR interaction in sepsis. Shock (2004) 1.07
Attenuation of IgG immune complex-induced acute lung injury by silencing C5aR in lung epithelial cells. FASEB J (2009) 1.07
Regulatory role of C5a on macrophage migration inhibitory factor release from neutrophils. J Immunol (2004) 1.07
The outcome of polymicrobial sepsis is independent of T and B cells. Shock (2011) 1.05
STAT3 and suppressor of cytokine signaling 3: potential targets in lung inflammatory responses. Expert Opin Ther Targets (2007) 1.05
The complement anaphylatoxin C5a induces apoptosis in adrenomedullary cells during experimental sepsis. PLoS One (2008) 1.03
The phosphatidylinositol 3-kinase signaling pathway exerts protective effects during sepsis by controlling C5a-mediated activation of innate immune functions. J Immunol (2007) 1.02
Sepsis-induced immune dysfunction: can immune therapies reduce mortality? J Clin Invest (2016) 1.02
Complement activation product C5a is a selective suppressor of TLR4-induced, but not TLR3-induced, production of IL-27(p28) from macrophages. J Immunol (2012) 1.02
MyD88-dependent production of IL-17F is modulated by the anaphylatoxin C5a via the Akt signaling pathway. FASEB J (2011) 1.01
Adenoviral-mediated overexpression of SOCS3 enhances IgG immune complex-induced acute lung injury. J Immunol (2006) 0.98
Divergent signaling pathways in phagocytic cells during sepsis. J Immunol (2006) 0.98
New insights into cellular mechanisms during sepsis. Immunol Res (2006) 0.97
New developments in C5a receptor signaling. Cell Health Cytoskelet (2012) 0.97
C5a-blockade improves burn-induced cardiac dysfunction. J Immunol (2007) 0.97
Complement dependency of cardiomyocyte release of mediators during sepsis. FASEB J (2011) 0.96
Inflammatory response of tracheobronchial epithelial cells to endotoxin. Am J Physiol Lung Cell Mol Physiol (2005) 0.96
Activator protein-1 activation in acute lung injury. Am J Pathol (2002) 0.95
Modulation of inflammation by interleukin-27. J Leukoc Biol (2013) 0.95
Agonists of proteinase-activated receptor-2 affect transendothelial migration and apoptosis of human neutrophils. Exp Dermatol (2007) 0.95
Ability of antioxidant liposomes to prevent acute and progressive pulmonary injury. Antioxid Redox Signal (2008) 0.94
Disturbed homeostasis of lung intercellular adhesion molecule-1 and vascular cell adhesion molecule-1 during sepsis. Am J Pathol (2004) 0.93
Topical nanoemulsion therapy reduces bacterial wound infection and inflammation after burn injury. Surgery (2010) 0.92
Complement in lung disease. Autoimmunity (2006) 0.92
Anti-inflammatory strategies for the treatment of sepsis. Expert Opin Biol Ther (2003) 0.91
The interaction between C5a and both C5aR and C5L2 receptors is required for production of G-CSF during acute inflammation. Eur J Immunol (2013) 0.90
Therapeutic potential of targeting IL-17 and IL-23 in sepsis. Clin Transl Med (2012) 0.89
Zonulin as prehaptoglobin2 regulates lung permeability and activates the complement system. Am J Physiol Lung Cell Mol Physiol (2013) 0.89
A key role of C5a/C5aR activation for the development of sepsis. J Leukoc Biol (2003) 0.88
Induction of M2 regulatory macrophages through the β2-adrenergic receptor with protection during endotoxemia and acute lung injury. J Innate Immun (2014) 0.87
Myeloid depletion of SOCS3 enhances LPS-induced acute lung injury through CCAAT/enhancer binding protein δ pathway. FASEB J (2013) 0.87