Published in Methods on October 01, 2007
Replicative senescence of mesenchymal stem cells: a continuous and organized process. PLoS One (2008) 4.37
MicroRNA signatures predict oestrogen receptor, progesterone receptor and HER2/neu receptor status in breast cancer. Breast Cancer Res (2009) 2.59
Podocyte-specific loss of functional microRNAs leads to rapid glomerular and tubular injury. J Am Soc Nephrol (2008) 2.51
The liver-specific microRNA miR-122 controls systemic iron homeostasis in mice. J Clin Invest (2011) 2.30
MicroRNA profiling and head and neck cancer. Comp Funct Genomics (2009) 1.68
MicroRNA expression after ionizing radiation in human endothelial cells. Radiat Oncol (2010) 1.38
The pro-apoptotic protein Bim is a microRNA target in kidney progenitors. J Am Soc Nephrol (2011) 1.27
MicroRNAs as immune regulators: implications for transplantation. Am J Transplant (2010) 1.16
Functional Studies of microRNAs in Neural Stem Cells: Problems and Perspectives. Front Neurosci (2012) 0.94
Opportunities and challenges for selected emerging technologies in cancer epidemiology: mitochondrial, epigenomic, metabolomic, and telomerase profiling. Cancer Epidemiol Biomarkers Prev (2012) 0.94
Oral squamous cell carcinoma: microRNA expression profiling and integrative analyses for elucidation of tumourigenesis mechanism. Mol Cancer (2016) 0.91
MicroRNA signatures as biomarkers and therapeutic target for CNS embryonal tumors: the pros and the cons. Int J Mol Sci (2014) 0.81
Differential expression of microRNAs in dorsal root ganglia after sciatic nerve injury. Neural Regen Res (2014) 0.80
Locked nucleic acid based beacons for surface interaction studies and biosensor development. Anal Chem (2009) 0.79
Bim gene dosage is critical in modulating nephron progenitor survival in the absence of microRNAs during kidney development. FASEB J (2017) 0.75
The MIQE guidelines: minimum information for publication of quantitative real-time PCR experiments. Clin Chem (2009) 40.90
The genome sequence of the malaria mosquito Anopheles gambiae. Science (2002) 20.36
MicroRNA-21 contributes to myocardial disease by stimulating MAP kinase signalling in fibroblasts. Nature (2008) 10.73
Balancing acts: molecular control of mammalian iron metabolism. Cell (2004) 7.82
Cyclical DNA methylation of a transcriptionally active promoter. Nature (2008) 7.62
Molecular mechanisms of translational control. Nat Rev Mol Cell Biol (2004) 6.39
Insights into RNA biology from an atlas of mammalian mRNA-binding proteins. Cell (2012) 6.22
Genome sequencing of pediatric medulloblastoma links catastrophic DNA rearrangements with TP53 mutations. Cell (2012) 6.07
Two to tango: regulation of Mammalian iron metabolism. Cell (2010) 5.45
Transient cyclical methylation of promoter DNA. Nature (2008) 5.19
Nonsense-mediated decay approaches the clinic. Nat Genet (2004) 5.12
DELLY: structural variant discovery by integrated paired-end and split-read analysis. Bioinformatics (2012) 4.79
Dissecting the genomic complexity underlying medulloblastoma. Nature (2012) 4.77
Replicative senescence of mesenchymal stem cells: a continuous and organized process. PLoS One (2008) 4.37
Drosophila miR2 induces pseudo-polysomes and inhibits translation initiation. Nature (2007) 3.77
A sensitive array for microRNA expression profiling (miChip) based on locked nucleic acids (LNA). RNA (2006) 3.71
A conserved motif in Argonaute-interacting proteins mediates functional interactions through the Argonaute PIWI domain. Nat Struct Mol Biol (2007) 3.62
Accounting for technical noise in single-cell RNA-seq experiments. Nat Methods (2013) 3.61
Phosphorylation of hUPF1 induces formation of mRNA surveillance complexes containing hSMG-5 and hSMG-7. Mol Cell (2003) 3.53
STAT3 mediates hepatic hepcidin expression and its inflammatory stimulation. Blood (2006) 3.38
The digital MIQE guidelines: Minimum Information for Publication of Quantitative Digital PCR Experiments. Clin Chem (2013) 3.38
Y14 and hUpf3b form an NMD-activating complex. Mol Cell (2003) 3.17
Integrative genomic analyses reveal an androgen-driven somatic alteration landscape in early-onset prostate cancer. Cancer Cell (2013) 3.08
Systemic iron homeostasis and the iron-responsive element/iron-regulatory protein (IRE/IRP) regulatory network. Annu Rev Nutr (2008) 2.98
Importin 8 is a gene silencing factor that targets argonaute proteins to distinct mRNAs. Cell (2009) 2.98
Exon-junction complex components specify distinct routes of nonsense-mediated mRNA decay with differential cofactor requirements. Mol Cell (2005) 2.79
Bruno acts as a dual repressor of oskar translation, promoting mRNA oligomerization and formation of silencing particles. Cell (2006) 2.77
3' end mRNA processing: molecular mechanisms and implications for health and disease. EMBO J (2008) 2.67
Aging and replicative senescence have related effects on human stem and progenitor cells. PLoS One (2009) 2.62
Gain-of-function mutations in interleukin-7 receptor-α (IL7R) in childhood acute lymphoblastic leukemias. J Exp Med (2011) 2.59
MicroRNA signatures predict oestrogen receptor, progesterone receptor and HER2/neu receptor status in breast cancer. Breast Cancer Res (2009) 2.59
Interactions between UPF1, eRFs, PABP and the exon junction complex suggest an integrated model for mammalian NMD pathways. EMBO J (2008) 2.52
Diverse roles of hnRNP L in mammalian mRNA processing: a combined microarray and RNAi analysis. RNA (2007) 2.48
Expression of the miR-17-92 polycistron in chronic myeloid leukemia (CML) CD34+ cells. Blood (2007) 2.46
Regulatory defects in liver and intestine implicate abnormal hepcidin and Cybrd1 expression in mouse hemochromatosis. Nat Genet (2003) 2.43
Vertebrate-type intron-rich genes in the marine annelid Platynereis dumerilii. Science (2005) 2.31
The liver-specific microRNA miR-122 controls systemic iron homeostasis in mice. J Clin Invest (2011) 2.30
Bone morphogenetic protein (BMP)-responsive elements located in the proximal and distal hepcidin promoter are critical for its response to HJV/BMP/SMAD. J Mol Med (Berl) (2009) 2.15
The role of ABCE1 in eukaryotic posttermination ribosomal recycling. Mol Cell (2010) 2.14
The RNA-binding protein repertoire of embryonic stem cells. Nat Struct Mol Biol (2013) 2.12
Pegylated interferon-α induced hypoferremia is associated with the immediate response to treatment in hepatitis C. Hepatology (2012) 2.12
Activating NOTCH1 mutations predict favorable early treatment response and long-term outcome in childhood precursor T-cell lymphoblastic leukemia. Blood (2006) 2.10
NMD: RNA biology meets human genetic medicine. Biochem J (2010) 2.09
Serum ferritin is derived primarily from macrophages through a nonclassical secretory pathway. Blood (2010) 2.02
c-Src-mediated phosphorylation of hnRNP K drives translational activation of specifically silenced mRNAs. Mol Cell Biol (2002) 1.98
Iron-regulatory proteins limit hypoxia-inducible factor-2alpha expression in iron deficiency. Nat Struct Mol Biol (2007) 1.96
Homodirectional changes in transcriptome composition and mRNA translation induced by rapamycin and heat shock. Nat Struct Biol (2003) 1.95
PABP and the poly(A) tail augment microRNA repression by facilitated miRISC binding. Nat Struct Mol Biol (2012) 1.91
A dual inhibitory mechanism restricts msl-2 mRNA translation for dosage compensation in Drosophila. Cell (2005) 1.91
Genome-wide RNAi screening identifies human proteins with a regulatory function in the early secretory pathway. Nat Cell Biol (2012) 1.88
Drosophila miR2 primarily targets the m7GpppN cap structure for translational repression. Mol Cell (2009) 1.82
CRX ChIP-seq reveals the cis-regulatory architecture of mouse photoreceptors. Genome Res (2010) 1.77
Previously uncharacterized isoforms of divalent metal transporter (DMT)-1: implications for regulation and cellular function. Proc Natl Acad Sci U S A (2002) 1.77
Translational control via protein-regulated upstream open reading frames. Cell (2011) 1.76
Complexes between the nonsense-mediated mRNA decay pathway factor human upf1 (up-frameshift protein 1) and essential nonsense-mediated mRNA decay factors in HeLa cells. Biochem J (2003) 1.74
Ca2+ channel blockers reverse iron overload by a new mechanism via divalent metal transporter-1. Nat Med (2007) 1.73
Direct and indirect effects of H-NS and Fis on global gene expression control in Escherichia coli. Nucleic Acids Res (2010) 1.71
A bone morphogenetic protein (BMP)-responsive element in the hepcidin promoter controls HFE2-mediated hepatic hepcidin expression and its response to IL-6 in cultured cells. J Mol Med (Berl) (2008) 1.71
Developmentally regulated switching of titin size alters myofibrillar stiffness in the perinatal heart. Circ Res (2004) 1.70
Disassembly of exon junction complexes by PYM. Cell (2009) 1.69
An Hfe-dependent pathway mediates hyposideremia in response to lipopolysaccharide-induced inflammation in mice. Nat Genet (2004) 1.68
microRNA-mediated messenger RNA deadenylation contributes to translational repression in mammalian cells. PLoS One (2009) 1.67
Anterior interbody fusion of the cervical spine with Zero-P spacer: prospective comparative study-clinical and radiological results at a minimum 2 years after surgery. Spine (Phila Pa 1976) (2013) 1.65
Treatment of thoracolumbar trauma by short-segment percutaneous transpedicular screw instrumentation: prospective comparative study with a minimum 2-year follow-up. J Neurosurg Spine (2013) 1.61
Altered body iron distribution and microcytosis in mice deficient in iron regulatory protein 2 (IRP2). Blood (2005) 1.59
Nonsense-mediated mRNA decay: from vacuum cleaner to Swiss army knife. Genome Biol (2004) 1.59
The need for transparency and good practices in the qPCR literature. Nat Methods (2013) 1.58
Integration of splicing, transport and translation to achieve mRNA quality control by the nonsense-mediated decay pathway. Genome Biol (2002) 1.58
Engineering the mouse genome with bacterial artificial chromosomes to create multipurpose alleles. Nat Biotechnol (2003) 1.57
Hfe acts in hepatocytes to prevent hemochromatosis. Cell Metab (2008) 1.55
Iron regulatory proteins are essential for intestinal function and control key iron absorption molecules in the duodenum. Cell Metab (2008) 1.54
The abundance of RNPS1, a protein component of the exon junction complex, can determine the variability in efficiency of the Nonsense Mediated Decay pathway. Nucleic Acids Res (2007) 1.53
Using the lambdaN peptide to tether proteins to RNAs. Methods Mol Biol (2004) 1.52
Unbiased RNAi screen for hepcidin regulators links hepcidin suppression to proliferative Ras/RAF and nutrient-dependent mTOR signaling. Blood (2014) 1.50
Heme controls ferroportin1 (FPN1) transcription involving Bach1, Nrf2 and a MARE/ARE sequence motif at position -7007 of the FPN1 promoter. Haematologica (2010) 1.47
Mechanism of translational regulation by miR-2 from sites in the 5' untranslated region or the open reading frame. RNA (2010) 1.46
Functions of hUpf3a and hUpf3b in nonsense-mediated mRNA decay and translation. RNA (2006) 1.46
Unusual bipartite mode of interaction between the nonsense-mediated decay factors, UPF1 and UPF2. EMBO J (2009) 1.44
Abnormally spliced beta-globin mRNAs: a single point mutation generates transcripts sensitive and insensitive to nonsense-mediated mRNA decay. Blood (2002) 1.43
Iron toxicity in diseases of aging: Alzheimer's disease, Parkinson's disease and atherosclerosis. J Alzheimers Dis (2009) 1.43
miChip: an array-based method for microRNA expression profiling using locked nucleic acid capture probes. Nat Protoc (2008) 1.43
Transcriptional complexes engaged by apo-estrogen receptor-alpha isoforms have divergent outcomes. EMBO J (2004) 1.42
Nuclear hormone 1α,25-dihydroxyvitamin D3 elicits a genome-wide shift in the locations of VDR chromatin occupancy. Nucleic Acids Res (2011) 1.38
RNA-binding proteins in Mendelian disease. Trends Genet (2013) 1.38
Iron-mediated degradation of IRP2, an unexpected pathway involving a 2-oxoglutarate-dependent oxygenase activity. Mol Cell Biol (2004) 1.37
Eukaryotic translation initiation factor 4GI and p97 promote cellular internal ribosome entry sequence-driven translation. Proc Natl Acad Sci U S A (2005) 1.36