Published in Mol Cell Endocrinol on August 31, 2007
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When NRF2 talks, who's listening? Antioxid Redox Signal (2010) 2.32
The cancer chemopreventive actions of phytochemicals derived from glucosinolates. Eur J Nutr (2008) 1.55
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Nrf2 participates in regulating maternal hepatic adaptations to pregnancy. J Cell Sci (2013) 0.80
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Gain and loss of function for glutathione synthesis: impact on advanced atherosclerosis in apolipoprotein E-deficient mice. Arterioscler Thromb Vasc Biol (2011) 0.80
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Estrogen receptor and PI3K/Akt signaling pathway involvement in S-(-)equol-induced activation of Nrf2/ARE in endothelial cells. PLoS One (2013) 0.79
Messenger RNA profile analysis deciphers new Esrrb responsive genes in prostate cancer cells. BMC Mol Biol (2015) 0.79
A glycine insertion in the estrogen-related receptor (ERR) is associated with enhanced expression of three cytochrome P450 genes in transgenic Drosophila melanogaster. PLoS One (2015) 0.77
Antiproliferative and Antiestrogenic Activities of Bonediol an Alkyl Catechol from Bonellia macrocarpa. Biomed Res Int (2015) 0.75
Keap1 is a redox-regulated substrate adaptor protein for a Cul3-dependent ubiquitin ligase complex. Mol Cell Biol (2004) 6.93
Distinct cysteine residues in Keap1 are required for Keap1-dependent ubiquitination of Nrf2 and for stabilization of Nrf2 by chemopreventive agents and oxidative stress. Mol Cell Biol (2003) 6.91
Nrf2 is a direct PERK substrate and effector of PERK-dependent cell survival. Mol Cell Biol (2003) 4.77
Caspase-3 activation via mitochondria is required for long-term depression and AMPA receptor internalization. Cell (2010) 4.15
Structure of the Keap1:Nrf2 interface provides mechanistic insight into Nrf2 signaling. EMBO J (2006) 2.67
Ubiquitination of Keap1, a BTB-Kelch substrate adaptor protein for Cul3, targets Keap1 for degradation by a proteasome-independent pathway. J Biol Chem (2005) 2.45
Crystal structure of the Kelch domain of human Keap1. J Biol Chem (2004) 2.04
Aβ(1-42) inhibition of LTP is mediated by a signaling pathway involving caspase-3, Akt1 and GSK-3β. Nat Neurosci (2011) 1.83
PGAM5, a Bcl-XL-interacting protein, is a novel substrate for the redox-regulated Keap1-dependent ubiquitin ligase complex. J Biol Chem (2006) 1.78
Kelch-like homologue 9 mutation is associated with an early onset autosomal dominant distal myopathy. Brain (2010) 1.76
Common botanical compounds inhibit the hedgehog signaling pathway in prostate cancer. Cancer Res (2010) 1.69
PGAM5 tethers a ternary complex containing Keap1 and Nrf2 to mitochondria. Exp Cell Res (2008) 1.64
Genistein alters methylation patterns in mice. J Nutr (2002) 1.60
Estrogen receptor-alpha mediates estrogen protection from angiotensin II-induced hypertension in conscious female mice. Am J Physiol Heart Circ Physiol (2006) 1.59
The soy isoflavone genistein decreases adipose deposition in mice. Endocrinology (2003) 1.43
Estrogen receptor alpha mediates estrogen's immune protection in autoimmune disease. J Immunol (2003) 1.40
Identification of oxygen-sensitive transcriptional programs in human embryonic stem cells. Stem Cells Dev (2008) 1.35
CAND1-mediated substrate adaptor recycling is required for efficient repression of Nrf2 by Keap1. Mol Cell Biol (2006) 1.27
Dihydro-CDDO-trifluoroethyl amide (dh404), a novel Nrf2 activator, suppresses oxidative stress in cardiomyocytes. PLoS One (2009) 1.24
Estrogen receptor-alpha gene deficiency enhances androgen biosynthesis in the mouse Leydig cell. Endocrinology (2003) 1.17
Distinct signaling pathways for induction of type II NOS by IFNgamma and LPS in BV-2 microglial cells. Neurochem Int (2005) 1.14
Impact on bone of an estrogen receptor-alpha gene loss of function mutation. J Clin Endocrinol Metab (2008) 1.12
Nitric oxide stimulates heme oxygenase-1 gene transcription via the Nrf2/ARE complex to promote vascular smooth muscle cell survival. Cardiovasc Res (2007) 1.11
Effects of interventions on oxidative stress and inflammation of cardiovascular diseases. World J Cardiol (2011) 1.11
Fiber type-specific nitric oxide protects oxidative myofibers against cachectic stimuli. PLoS One (2008) 1.10
Cul3-mediated Nrf2 ubiquitination and antioxidant response element (ARE) activation are dependent on the partial molar volume at position 151 of Keap1. Biochem J (2009) 1.09
Modulation of phototropic responsiveness in Arabidopsis through ubiquitination of phototropin 1 by the CUL3-Ring E3 ubiquitin ligase CRL3(NPH3). Plant Cell (2011) 1.09
Phytoestrogens in common herbs regulate prostate cancer cell growth in vitro. Nutr Cancer (2004) 1.03
Disruption of estrogen receptor signaling enhances intestinal neoplasia in Apc(Min/+) mice. Carcinogenesis (2009) 1.02
Characterization of the nuclear import and export functions of Ikappa B(epsilon). J Biol Chem (2002) 1.00
Conserved solvent and side-chain interactions in the 1.35 Angstrom structure of the Kelch domain of Keap1. Acta Crystallogr D Biol Crystallogr (2005) 0.99
Estrogen receptor-alpha mediates estrogen facilitation of baroreflex heart rate responses in conscious mice. Am J Physiol Heart Circ Physiol (2004) 0.98
Estrogen receptor-alpha deficiency promotes increased TNF-alpha secretion and bacterial killing by murine macrophages in response to microbial stimuli in vitro. J Leukoc Biol (2004) 0.98
Aggressive prostate cancer is prevented in ERαKO mice and stimulated in ERβKO TRAMP mice. Endocrinology (2012) 0.96
Estrogen receptor alpha-mediated events promote sex-specific diabetic glomerular hypertrophy. Am J Physiol Renal Physiol (2004) 0.96
Identification and characterization of two novel splicing isoforms of human estrogen-related receptor beta. J Clin Endocrinol Metab (2005) 0.95
Ceramide synthase 1 is regulated by proteasomal mediated turnover. Biochim Biophys Acta (2009) 0.95
Genome-wide analysis of changes in early gene expression induced by oestrogen. Genes Cells (2002) 0.93
Expression of aquaporins in the efferent ductules, sperm counts, and sperm motility in estrogen receptor-alpha deficient mice fed lab chow versus casein. Mol Reprod Dev (2006) 0.90
Dietary soy isoflavones and estrone protect ovariectomized ERalphaKO and wild-type mice from carcinogen-induced colon cancer. J Nutr (2004) 0.89
Magnolia polyphenols attenuate oxidative and inflammatory responses in neurons and microglial cells. J Neuroinflammation (2013) 0.89
Fibroblast growth factor 21 as a possible endogenous factor inhibits apoptosis in cardiac endothelial cells. Chin Med J (Engl) (2010) 0.89
Proteomic quantification and site-mapping of S-nitrosylated proteins using isobaric iodoTMT reagents. J Proteome Res (2014) 0.89
Disruption of the Keap1-containing ubiquitination complex as an antioxidant therapy. Curr Top Med Chem (2007) 0.89
Coordinate regulation of basal and cyclic 5'-adenosine monophosphate (cAMP)-activated expression of human chorionic gonadotropin-alpha by Ets-2 and cAMP-responsive element binding protein. Mol Endocrinol (2005) 0.89
Estrogen receptor-alpha and -beta and aromatase knockout effects on lower limb muscle mass and contractile function in female mice. Am J Physiol Endocrinol Metab (2009) 0.88
Genistein affects HER2 protein concentration, activation, and promoter regulation in BT-474 human breast cancer cells. Endocrine (2007) 0.87
Estrogen receptor alpha is required for mammary development and the induction of mammary hyperplasia and epigenetic alterations in the aromatase transgenic mice. J Steroid Biochem Mol Biol (2005) 0.87
Estrogen modulation of baroreflex function in conscious mice. Am J Physiol Regul Integr Comp Physiol (2003) 0.87
Stress-induced ER to Golgi translocation of ceramide synthase 1 is dependent on proteasomal processing. Exp Cell Res (2009) 0.87
The neuroprotective effects of apocynin. Front Biosci (Elite Ed) (2012) 0.87
Gold nanoparticle-mediated detection of circulating cancer cells. Clin Lab Med (2012) 0.86
Histone deacetylase 2 cell autonomously suppresses excitatory and enhances inhibitory synaptic function in CA1 pyramidal neurons. J Neurosci (2013) 0.85
Synthesis of radiometal-labeled and fluorescent cell-permeating peptide-PNA conjugates for targeting the bcl-2 proto-oncogene. Bioconjug Chem (2003) 0.84
Radiometal-labeled peptide-PNA conjugates for targeting bcl-2 expression: preparation, characterization, and in vitro mRNA binding. Bioconjug Chem (2002) 0.84
Molecular imaging of bcl-2 expression in small lymphocytic lymphoma using 111In-labeled PNA-peptide conjugates. J Nucl Med (2008) 0.84
Estrogenic regulation of host immunity against an estrogen receptor-negative human breast cancer. Clin Cancer Res (2006) 0.84
Regulation of nitric oxide-dependent vasodilation in coronary arteries of estrogen receptor-alpha-deficient mice. Am J Physiol Heart Circ Physiol (2003) 0.83
Phytosterol Pygeum africanum regulates prostate cancer in vitro and in vivo. Endocrine (2007) 0.83
Morphological comparison of the testis and efferent ductules between wild-type and estrogen receptor alpha knockout mice during postnatal development. J Anat (2009) 0.82
Estrogen receptor-independent catechol estrogen binding activity: protein binding studies in wild-type, Estrogen receptor-alpha KO, and aromatase KO mice tissues. Biochemistry (2004) 0.82
Molecular mechanisms that regulate transcription factor localization suggest new targets for drug development. Adv Drug Deliv Rev (2003) 0.81
NitroDIGE analysis reveals inhibition of protein S-nitrosylation by epigallocatechin gallates in lipopolysaccharide-stimulated microglial cells. J Neuroinflammation (2014) 0.80
Chromosomal integration of a synthetic expression control sequence achieves poly-gamma-glutamate production in a Bacillus subtilis strain. Biotechnol Prog (2010) 0.80
Inhibition of hedgehog/Gli signaling by botanicals: a review of compounds with potential hedgehog pathway inhibitory activities. Curr Cancer Drug Targets (2013) 0.80
Crystallization and initial crystallographic analysis of the Kelch domain from human Keap1. Acta Crystallogr D Biol Crystallogr (2004) 0.80
Discovery of putative oocyte quality markers by comparative ExacTag proteomics. Proteomics Clin Appl (2010) 0.79
Enhanced induction of mucin-depleted foci in estrogen receptor {beta} knockout mice. Cancer Prev Res (Phila) (2010) 0.79
Expression of a novel C-type lectin in the mouse vagina. Endocrinology (2003) 0.78
CRM1-mediated nuclear export is present during porcine embryogenesis, but is not required for early cleavage. Biol Reprod (2002) 0.78
Elongation factor 1 alpha1 and genes associated with Usher syndromes are downstream targets of GBX2. PLoS One (2012) 0.77
[Study on the involvement of ZO-1 gene in leukemogenesis]. Zhonghua Xue Ye Xue Za Zhi (2009) 0.76
Estrogen receptor ESR1 is indispensable for the induction of persistent vaginal change by neonatal 5alpha-dihydrotestosterone exposure in mice. Biol Reprod (2009) 0.76
Impact of Chronic Total Occlusion in a Noninfarct-related Artery on Clinical Outcomes in Patients With Acute ST-elevation Myocardial Infarction Undergoing Primary Percutaneous Coronary Intervention. Medicine (Baltimore) (2016) 0.75
[GFP used as a reporter system for optimization of K562 cell transfection]. Zhongguo Shi Yan Xue Ye Xue Za Zhi (2008) 0.75
The Differential Fate of Mesonephric Tubular-Derived Efferent Ductules in Estrogen Receptor-α Knockout Versus Wild-Type Female Mice. Endocrinology (2000) 0.75
[Analysis of full-length gene sequence of rabies vaccine virus aG strain]. Bing Du Xue Bao (2013) 0.75
[Alpha-GalCer reduces acute graft-versus-host disease by inducing Th2 polarization of donor mice T cells]. Zhonghua Xue Ye Xue Za Zhi (2011) 0.75
Methoxychlor Stimulates Estrogen-Responsive Messenger Ribonucleic Acids in Mouse Uterus through a Non-Estrogen Receptor (Non-ER)α and Non-ERβ Mechanism. Endocrinology (1999) 0.75
Transcription and Translation of Estrogen Receptor-β in the Male Reproductive Tract of Estrogen Receptor-α Knock-Out and Wild-Type Mice. Endocrinology (1998) 0.75
[Preliminary study on leukemia related gene zo-1 involved in pathogenesis of leukemia]. Zhongguo Shi Yan Xue Ye Xue Za Zhi (2009) 0.75
[Reversion of multidrug resistance in HL-60/VCR cells by down-regulation of bcl-2 with bcl-2 siRNA]. Zhongguo Shi Yan Xue Ye Xue Za Zhi (2005) 0.75
[Study on the genotyping of 113 Mycobacterium tuberculosis strains isolated in Beijing based on 13 variable number of tandem DNA repeats]. Zhonghua Liu Xing Bing Xue Za Zhi (2006) 0.75
[The application of two-dimensional liquid phase chromatography to separation of total protein of Leymus chinensis shoot]. Zhi Wu Sheng Li Yu Fen Zi Sheng Wu Xue Xue Bao (2007) 0.75
[Establishment of the standard operation program on multiple loci variable numbers tandem repeats analysis typing on Mycobacterium tuberculosis]. Zhonghua Liu Xing Bing Xue Za Zhi (2008) 0.75
Corrigendum: Discovery of a Novel Seminal Fluid Microbiome and Influence of Estrogen Receptor Alpha Genetic Status. Sci Rep (2016) 0.75
[Construction and functional identification of red fluorescent protein reporter plasmid for human catalase gene]. Nan Fang Yi Ke Da Xue Xue Bao (2009) 0.75
Effects of probucol on angiotensin II-induced BMP-2 expression in human umbilical vein endothelial cells. Mol Med Rep (2012) 0.75
α-GalCer administration after allogeneic bone marrow transplantation improves immune reconstitution in mice. Chin Med Sci J (2011) 0.75
[I Fibroblast growth factor 21 is a metabolic regulator]. Sheng Li Ke Xue Jin Zhan (2011) 0.75
Prior ischemic stroke is not associated with worse clinical outcomes in patients undergoing percutaneous coronary intervention. Clin Invest Med (2014) 0.75