Published in J Biol Chem on October 10, 2007
DNA helicases Sgs1 and BLM promote DNA double-strand break resection. Genes Dev (2008) 5.07
Analysis of protein dynamics at active, stalled, and collapsed replication forks. Genes Dev (2011) 2.47
The BRCA1-RAP80 complex regulates DNA repair mechanism utilization by restricting end resection. J Biol Chem (2011) 1.91
Replication protein A: directing traffic at the intersection of replication and repair. Front Biosci (Landmark Ed) (2010) 1.77
More forks on the road to replication stress recovery. J Mol Cell Biol (2011) 1.64
A genome-wide camptothecin sensitivity screen identifies a mammalian MMS22L-NFKBIL2 complex required for genomic stability. Mol Cell (2010) 1.50
Distinct roles for DNA-PK, ATM and ATR in RPA phosphorylation and checkpoint activation in response to replication stress. Nucleic Acids Res (2012) 1.47
A PP4 phosphatase complex dephosphorylates RPA2 to facilitate DNA repair via homologous recombination. Nat Struct Mol Biol (2010) 1.45
Human RPA phosphorylation by ATR stimulates DNA synthesis and prevents ssDNA accumulation during DNA-replication stress. J Cell Sci (2009) 1.44
The FANCM/FAAP24 complex is required for the DNA interstrand crosslink-induced checkpoint response. Mol Cell (2010) 1.35
SETD2 is required for DNA double-strand break repair and activation of the p53-mediated checkpoint. Elife (2014) 1.33
DNA2 and EXO1 in replication-coupled, homology-directed repair and in the interplay between HDR and the FA/BRCA network. Cell Cycle (2012) 1.23
RNAi-based screening identifies the Mms22L-Nfkbil2 complex as a novel regulator of DNA replication in human cells. EMBO J (2010) 1.19
Two distinct modes of ATR activation orchestrated by Rad17 and Nbs1. Cell Rep (2013) 1.19
The role of RPA2 phosphorylation in homologous recombination in response to replication arrest. Carcinogenesis (2010) 1.14
RPA phosphorylation facilitates mitotic exit in response to mitotic DNA damage. Proc Natl Acad Sci U S A (2008) 1.14
Cyclin-dependent kinases (cdks) and the DNA damage response: rationale for cdk inhibitor-chemotherapy combinations as an anticancer strategy for solid tumors. Expert Opin Ther Targets (2010) 1.10
RPA-coated single-stranded DNA as a platform for post-translational modifications in the DNA damage response. Cell Res (2014) 1.10
Controlling DNA-end resection: a new task for CDKs. Front Genet (2013) 1.09
Dysregulation of DNA polymerase κ recruitment to replication forks results in genomic instability. EMBO J (2011) 1.08
Bacillus subtilis RecO nucleates RecA onto SsbA-coated single-stranded DNA. J Biol Chem (2008) 1.02
Rescue of replication failure by Fanconi anaemia proteins. Chromosoma (2011) 1.02
Defective DNA double-strand break repair underlies enhanced tumorigenesis and chromosomal instability in p27-deficient mice with growth factor-induced oligodendrogliomas. Oncogene (2010) 1.02
DNA-PK-dependent RPA2 hyperphosphorylation facilitates DNA repair and suppresses sister chromatid exchange. PLoS One (2011) 1.00
Ionizing radiation-dependent and independent phosphorylation of the 32-kDa subunit of replication protein A during mitosis. Nucleic Acids Res (2009) 1.00
Polo-like kinase 3 regulates CtIP during DNA double-strand break repair in G1. J Cell Biol (2014) 0.97
Involvement of nucleotide excision and mismatch repair mechanisms in double strand break repair. Curr Genomics (2009) 0.96
Mitotic crisis: the unmasking of a novel role for RPA. Cell Cycle (2009) 0.96
RPA inhibition increases replication stress and suppresses tumor growth. Cancer Res (2014) 0.95
Human replication protein A-Rad52-single-stranded DNA complex: stoichiometry and evidence for strand transfer regulation by phosphorylation. Biochemistry (2009) 0.94
Phosphorylated RPA recruits PALB2 to stalled DNA replication forks to facilitate fork recovery. J Cell Biol (2014) 0.94
DNA-PK phosphorylation of RPA32 Ser4/Ser8 regulates replication stress checkpoint activation, fork restart, homologous recombination and mitotic catastrophe. DNA Repair (Amst) (2014) 0.92
LIM Protein Ajuba Participates in the Repression of the ATR-Mediated DNA Damage Response. Front Genet (2013) 0.91
DNA structure-specific priming of ATR activation by DNA-PKcs. J Cell Biol (2013) 0.91
Hyperphosphorylation of replication protein A in cisplatin-resistant and -sensitive head and neck squamous cell carcinoma cell lines. Head Neck (2010) 0.90
Inhibition of topoisomerase I prevents chromosome breakage at common fragile sites. DNA Repair (Amst) (2010) 0.89
Regulatory functions of the N-terminal domain of the 70-kDa subunit of replication protein A (RPA). J Biol Chem (2008) 0.89
Efficient herpes simplex virus 1 replication requires cellular ATR pathway proteins. J Virol (2012) 0.89
In vitro analysis of the role of replication protein A (RPA) and RPA phosphorylation in ATR-mediated checkpoint signaling. J Biol Chem (2012) 0.87
STAT3 interrupts ATR-Chk1 signaling to allow oncovirus-mediated cell proliferation. Proc Natl Acad Sci U S A (2014) 0.87
Differential response of normal and malignant urothelial cells to CHK1 and ATM inhibitors. Oncogene (2014) 0.87
PARG is dispensable for recovery from transient replicative stress but required to prevent detrimental accumulation of poly(ADP-ribose) upon prolonged replicative stress. Nucleic Acids Res (2014) 0.85
Transcription-dependent activation of ataxia telangiectasia mutated prevents DNA-dependent protein kinase-mediated cell death in response to topoisomerase I poison. J Biol Chem (2010) 0.85
Divergent S phase checkpoint activation arising from prereplicative complex deficiency controls cell survival. Mol Biol Cell (2009) 0.84
Structure of the herpes simplex virus 1 genome: manipulation of nicks and gaps can abrogate infectivity and alter the cellular DNA damage response. J Virol (2014) 0.84
Proteasome inhibition suppresses DNA-dependent protein kinase activation caused by camptothecin. DNA Repair (Amst) (2009) 0.84
Parvovirus infection-induced DNA damage response. Future Virol (2013) 0.83
Microarray-based analysis of cell-cycle gene expression during spermatogenesis in the mouse. Biol Reprod (2010) 0.82
ATR inhibition preferentially targets homologous recombination-deficient tumor cells. Oncogene (2014) 0.82
Cdk1 regulates the temporal recruitment of telomerase and Cdc13-Stn1-Ten1 complex for telomere replication. Mol Cell Biol (2013) 0.82
Herpes simplex virus type 1 single strand DNA binding protein and helicase/primase complex disable cellular ATR signaling. PLoS Pathog (2013) 0.82
RECQL5 and BLM exhibit divergent functions in cells defective for the Fanconi anemia pathway. Nucleic Acids Res (2014) 0.82
Deletion of BRCA2 exon 27 causes defects in response to both stalled and collapsed replication forks. Mutat Res (2014) 0.81
Regulators of homologous recombination repair as novel targets for cancer treatment. Front Genet (2015) 0.81
Adeno-associated virus type 2 modulates the host DNA damage response induced by herpes simplex virus 1 during coinfection. J Virol (2011) 0.81
Defining ATM-Independent Functions of the Mre11 Complex with a Novel Mouse Model. Mol Cancer Res (2015) 0.81
Timing is everything: cell cycle control of Rad52. Cell Div (2010) 0.81
Response to DNA damage: why do we need to focus on protein phosphatases? Front Oncol (2013) 0.81
The transcriptome of the bowhead whale Balaena mysticetus reveals adaptations of the longest-lived mammal. Aging (Albany NY) (2014) 0.81
Cdk5 promotes DNA replication stress checkpoint activation through RPA-32 phosphorylation, and impacts on metastasis free survival in breast cancer patients. Cell Cycle (2015) 0.79
Pot1a prevents telomere dysfunction and ATM-dependent neuronal loss. J Neurosci (2014) 0.78
Interplay of DNA damage and cell cycle signaling at the level of human replication protein A. DNA Repair (Amst) (2014) 0.78
The checkpoint clamp protein Rad9 facilitates DNA-end resection and prevents alternative non-homologous end joining. Cell Cycle (2014) 0.78
The DNA damage response and checkpoint adaptation in Saccharomyces cerevisiae: distinct roles for the replication protein A2 (Rfa2) N-terminus. Genetics (2015) 0.77
Detection of posttranslational modifications of replication protein A. Methods Mol Biol (2012) 0.76
Characterization of the interaction between Rfa1 and Rad24 in Saccharomyces cerevisiae. PLoS One (2015) 0.76
Key mediators of somatic ATR signaling localize to unpaired chromosomes in spermatocytes. Development (2015) 0.76
Human CDK18 promotes replication stress signaling and genome stability. Nucleic Acids Res (2016) 0.76
Replication Protein A Presents Canonical Functions and Is Also Involved in the Differentiation Capacity of Trypanosoma cruzi. PLoS Negl Trop Dis (2016) 0.75
Extensive RPA2 hyperphosphorylation promotes apoptosis in response to DNA replication stress in CHK1 inhibited cells. Nucleic Acids Res (2015) 0.75
Rapid Diminution in the Level and Activity of DNA-Dependent Protein Kinase in Cancer Cells by a Reactive Nitro-Benzoxadiazole Compound. Int J Mol Sci (2016) 0.75
Phosphorylation and cellular function of the human Rpa2 N-terminus in the budding yeast Saccharomyces cerevisiae. Exp Cell Res (2014) 0.75
A mechanism for 1,4-Benzoquinone-induced genotoxicity. Oncotarget (2016) 0.75
Induced expression of nucleolin phosphorylation-deficient mutant confers dominant-negative effect on cell proliferation. PLoS One (2014) 0.75
A phosphorylation-and-ubiquitylation circuitry driving ATR activation and homologous recombination. Nucleic Acids Res (2017) 0.75
Replication protein A (RPA) phosphorylation prevents RPA association with replication centers. Mol Cell Biol (2004) 1.89
Stress-dependent nucleolin mobilization mediated by p53-nucleolin complex formation. Mol Cell Biol (2002) 1.57
A PP4 phosphatase complex dephosphorylates RPA2 to facilitate DNA repair via homologous recombination. Nat Struct Mol Biol (2010) 1.45
Human RPA phosphorylation by ATR stimulates DNA synthesis and prevents ssDNA accumulation during DNA-replication stress. J Cell Sci (2009) 1.44
RPA phosphorylation facilitates mitotic exit in response to mitotic DNA damage. Proc Natl Acad Sci U S A (2008) 1.14
Novel checkpoint response to genotoxic stress mediated by nucleolin-replication protein a complex formation. Mol Cell Biol (2005) 1.14
Mitotic crisis: the unmasking of a novel role for RPA. Cell Cycle (2009) 0.96
Specific domains of nucleolin interact with Hdm2 and antagonize Hdm2-mediated p53 ubiquitination. FEBS J (2011) 0.89
Adenomatous polyposis coli protein regulates the cellular response to DNA replication stress. Int J Biochem Cell Biol (2011) 0.84