Published in J Cell Sci on November 01, 2007
Endosome maturation. EMBO J (2011) 5.22
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Rab7 regulates late endocytic trafficking downstream of multivesicular body biogenesis and cargo sequestration. J Biol Chem (2009) 2.11
Host cell factors and functions involved in vesicular stomatitis virus entry. J Virol (2008) 1.83
Sorting of EGF and transferrin at the plasma membrane and by cargo-specific signaling to EEA1-enriched endosomes. J Cell Sci (2008) 1.70
The small GTPase Rab7 as a central regulator of hepatocellular lipophagy. Hepatology (2015) 1.62
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Recruitment of dynein to late endosomes and lysosomes through light intermediate chains. Mol Biol Cell (2010) 1.10
Annexin A8 regulates late endosome organization and function. Mol Biol Cell (2008) 1.03
Basal body proteins regulate Notch signaling through endosomal trafficking. J Cell Sci (2014) 1.01
HGF-induced invasion by prostate tumor cells requires anterograde lysosome trafficking and activity of Na+-H+ exchangers. J Cell Sci (2010) 1.00
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A competitive nucleotide binding inhibitor: in vitro characterization of Rab7 GTPase inhibition. ACS Chem Biol (2012) 0.92
Dmon1 controls recruitment of Rab7 to maturing endosomes in Drosophila. J Cell Sci (2013) 0.91
GISP increases neurotransmitter receptor stability by down-regulating ESCRT-mediated lysosomal degradation. Neurosci Lett (2009) 0.91
ATP is released from autophagic vesicles to the extracellular space in a VAMP7-dependent manner. Autophagy (2012) 0.90
PKA-dependent dynein switching from lysosomes to adenovirus: a novel form of host-virus competition. J Cell Biol (2014) 0.88
Supporting a role for the GTPase Rab7 in prostate cancer progression. PLoS One (2014) 0.87
Vimentin phosphorylation and assembly are regulated by the small GTPase Rab7a. Biochim Biophys Acta (2013) 0.85
Myosin-Va-interacting protein, RILPL2, controls cell shape and neuronal morphogenesis via Rac signaling. J Cell Sci (2009) 0.84
RILP interacts with HOPS complex via VPS41 subunit to regulate endocytic trafficking. Sci Rep (2014) 0.84
Sprouty 2 binds ESCRT-II factor Eap20 and facilitates HIV-1 gag release. J Virol (2011) 0.81
The ancient small GTPase Rab21 functions in intermediate endocytic steps in trypanosomes. Eukaryot Cell (2013) 0.78
Cholesterol and ORP1L-mediated ER contact sites control autophagosome transport and fusion with the endocytic pathway. Nat Commun (2016) 0.78
Mechanisms and functions of lysosome positioning. J Cell Sci (2016) 0.78
The Legionella pneumophila effector protein, LegC7, alters yeast endosomal trafficking. PLoS One (2015) 0.77
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A new V-ATPase regulatory mechanism mediated by the Rab interacting lysosomal protein (RILP). Commun Integr Biol (2014) 0.75
Factors Affecting Phenotype Variability in a Family with CMT2B: Gender and LRSAM1 Genotype. Case Rep Neurol (2016) 0.75
Charcot Marie Tooth 2B Peripheral Sensory Neuropathy: How Rab7 Mutations Impact NGF Signaling? Int J Mol Sci (2017) 0.75
Characterization of Rab-interacting lysosomal protein in the brain of Bombyx mori. Histochem Cell Biol (2013) 0.75
p62/SQSTM1 binds directly to Atg8/LC3 to facilitate degradation of ubiquitinated protein aggregates by autophagy. J Biol Chem (2007) 21.73
Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes. Autophagy (2007) 20.92
Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy (2012) 20.08
p62/SQSTM1 forms protein aggregates degraded by autophagy and has a protective effect on huntingtin-induced cell death. J Cell Biol (2005) 18.23
The ESCRT machinery in endosomal sorting of ubiquitylated membrane proteins. Nature (2009) 6.99
The biogenesis of multivesicular endosomes. Nat Rev Mol Cell Biol (2004) 6.31
Hrs sorts ubiquitinated proteins into clathrin-coated microdomains of early endosomes. Nat Cell Biol (2002) 5.83
Role for Rab7 in maturation of late autophagic vacuoles. J Cell Sci (2004) 5.19
Monitoring autophagic degradation of p62/SQSTM1. Methods Enzymol (2009) 4.74
Programmed autophagy in the Drosophila fat body is induced by ecdysone through regulation of the PI3K pathway. Dev Cell (2004) 4.53
The adaptor protein p62/SQSTM1 targets invading bacteria to the autophagy pathway. J Immunol (2009) 4.31
Functional multivesicular bodies are required for autophagic clearance of protein aggregates associated with neurodegenerative disease. J Cell Biol (2007) 4.30
Protein sorting into multivesicular endosomes. Curr Opin Cell Biol (2003) 4.04
Regulation of membrane traffic by phosphoinositide 3-kinases. J Cell Sci (2006) 3.72
Promoting basal levels of autophagy in the nervous system enhances longevity and oxidant resistance in adult Drosophila. Autophagy (2007) 3.45
Endocytic pathways regulate Toll-like receptor 4 signaling and link innate and adaptive immunity. EMBO J (2006) 3.07
Hrs regulates multivesicular body formation via ESCRT recruitment to endosomes. J Cell Biol (2003) 3.07
STAM and Hrs are subunits of a multivalent ubiquitin-binding complex on early endosomes. J Biol Chem (2003) 3.00
Regulation of ubiquitin-binding proteins by monoubiquitination. Nat Cell Biol (2006) 2.99
The E3 ubiquitin ligase AIP4 mediates ubiquitination and sorting of the G protein-coupled receptor CXCR4. Dev Cell (2003) 2.97
Ref(2)P, the Drosophila melanogaster homologue of mammalian p62, is required for the formation of protein aggregates in adult brain. J Cell Biol (2008) 2.90
Rab5 and Rab7 control endocytic sorting along the axonal retrograde transport pathway. Neuron (2006) 2.79
Misfolding diverts CFTR from recycling to degradation: quality control at early endosomes. J Cell Biol (2004) 2.74
Modulation of receptor recycling and degradation by the endosomal kinesin KIF16B. Cell (2005) 2.67
Endosomal and non-endosomal functions of ESCRT proteins. Trends Cell Biol (2006) 2.61
FYCO1 is a Rab7 effector that binds to LC3 and PI3P to mediate microtubule plus end-directed vesicle transport. J Cell Biol (2010) 2.57
Double-sided ubiquitin binding of Hrs-UIM in endosomal protein sorting. Nat Struct Mol Biol (2006) 2.47
ESCRTs and Fab1 regulate distinct steps of autophagy. Curr Biol (2007) 2.46
Ubiquitination of alpha 5 beta 1 integrin controls fibroblast migration through lysosomal degradation of fibronectin-integrin complexes. Dev Cell (2010) 2.37
Alfy, a novel FYVE-domain-containing protein associated with protein granules and autophagic membranes. J Cell Sci (2004) 2.35
PtdIns(3)P controls cytokinesis through KIF13A-mediated recruitment of FYVE-CENT to the midbody. Nat Cell Biol (2010) 2.33
Phagosomes fuse with late endosomes and/or lysosomes by extension of membrane protrusions along microtubules: role of Rab7 and RILP. Mol Cell Biol (2003) 2.33
The Rab11a GTPase controls Toll-like receptor 4-induced activation of interferon regulatory factor-3 on phagosomes. Immunity (2010) 2.29
SLC9A6 mutations cause X-linked mental retardation, microcephaly, epilepsy, and ataxia, a phenotype mimicking Angelman syndrome. Am J Hum Genet (2008) 2.16
The mammalian phosphatidylinositol 3-phosphate 5-kinase (PIKfyve) regulates endosome-to-TGN retrograde transport. J Cell Sci (2006) 2.12
The selective macroautophagic degradation of aggregated proteins requires the PI3P-binding protein Alfy. Mol Cell (2010) 2.12
Defective downregulation of receptor tyrosine kinases in cancer. EMBO J (2004) 2.05
Modulation of Rab5 and Rab7 recruitment to phagosomes by phosphatidylinositol 3-kinase. Mol Cell Biol (2003) 2.03
p62/SQSTM1 and ALFY interact to facilitate the formation of p62 bodies/ALIS and their degradation by autophagy. Autophagy (2010) 1.93
Clathrin-dependent endocytosis. Biochem J (2004) 1.89
Cbl-dependent ubiquitination is required for progression of EGF receptors into clathrin-coated pits. Mol Biol Cell (2004) 1.82
Endocytosis and signaling. Curr Opin Cell Biol (2011) 1.78
A phosphatidylinositol 3-kinase class III sub-complex containing VPS15, VPS34, Beclin 1, UVRAG and BIF-1 regulates cytokinesis and degradative endocytic traffic. Exp Cell Res (2010) 1.75
The ESCRT-III subunit hVps24 is required for degradation but not silencing of the epidermal growth factor receptor. Mol Biol Cell (2006) 1.74
The small GTPase Rab22 interacts with EEA1 and controls endosomal membrane trafficking. J Cell Sci (2002) 1.74
Flat clathrin coats on endosomes mediate degradative protein sorting by scaffolding Hrs in dynamic microdomains. J Cell Sci (2006) 1.71
The small GTPase Rab7 controls the endosomal trafficking and neuritogenic signaling of the nerve growth factor receptor TrkA. J Neurosci (2005) 1.69
Eap45 in mammalian ESCRT-II binds ubiquitin via a phosphoinositide-interacting GLUE domain. J Biol Chem (2005) 1.68
Fab1 phosphatidylinositol 3-phosphate 5-kinase controls trafficking but not silencing of endocytosed receptors. Mol Biol Cell (2006) 1.68
Alix regulates cortical actin and the spatial distribution of endosomes. J Cell Sci (2005) 1.67
Autophagic degradation of dBruce controls DNA fragmentation in nurse cells during late Drosophila melanogaster oogenesis. J Cell Biol (2010) 1.65
Autophagy in tumour suppression and promotion. Mol Oncol (2009) 1.64
Rab coupling protein (RCP), a novel Rab4 and Rab11 effector protein. J Biol Chem (2002) 1.62
Molecular mechanisms of the membrane sculpting ESCRT pathway. Cold Spring Harb Perspect Biol (2013) 1.58
The growth-regulatory protein HCRP1/hVps37A is a subunit of mammalian ESCRT-I and mediates receptor down-regulation. Mol Biol Cell (2004) 1.58
Antibody crossreactivity between the tumour suppressor PHLPP1 and the proto-oncogene β-catenin. EMBO Rep (2012) 1.57
Salmonella impairs RILP recruitment to Rab7 during maturation of invasion vacuoles. Mol Biol Cell (2004) 1.56
Actin-based motility of endosomes is linked to the polar tip growth of root hairs. Eur J Cell Biol (2005) 1.52
Regulation of endocytic recycling of KCNQ1/KCNE1 potassium channels. Circ Res (2007) 1.52
Early endosomal regulation of Smad-dependent signaling in endothelial cells. J Biol Chem (2002) 1.52
Microtubule motors control membrane dynamics of Salmonella-containing vacuoles. J Cell Sci (2004) 1.50
A dual function for Deep orange in programmed autophagy in the Drosophila melanogaster fat body. Exp Cell Res (2006) 1.50
Differential functions of Hrs and ESCRT proteins in endocytic membrane trafficking. Exp Cell Res (2007) 1.46
Multivesicular endosome biogenesis in the absence of ESCRTs. Traffic (2009) 1.44
Functional characterization of Rab7 mutant proteins associated with Charcot-Marie-Tooth type 2B disease. J Neurosci (2008) 1.44
Cell death during Drosophila melanogaster early oogenesis is mediated through autophagy. Autophagy (2009) 1.43
Comparative analysis of ESCRT-I, ESCRT-II and ESCRT-III function in Drosophila by efficient isolation of ESCRT mutants. J Cell Sci (2009) 1.42
p62 at the interface of autophagy, oxidative stress signaling, and cancer. Antioxid Redox Signal (2012) 1.42
Connexin43 acts as a colorectal cancer tumor suppressor and predicts disease outcome. Int J Cancer (2011) 1.39
Shaping development with ESCRTs. Nat Cell Biol (2011) 1.38
How do ESCRT proteins control autophagy? J Cell Sci (2009) 1.37
Ultrastructural characterization of giant endosomes induced by GTPase-deficient Rab5. Histochem Cell Biol (2009) 1.36