Published in Cell Res on August 21, 2012
Biology of PIWI-interacting RNAs: new insights into biogenesis and function inside and outside of germlines. Genes Dev (2012) 1.75
CapSeq and CIP-TAP identify Pol II start sites and reveal capped small RNAs as C. elegans piRNA precursors. Cell (2012) 1.61
Pachytene piRNAs instruct massive mRNA elimination during late spermiogenesis. Cell Res (2014) 1.37
Tdrkh is essential for spermatogenesis and participates in primary piRNA biogenesis in the germline. EMBO J (2013) 1.22
MIWI and piRNA-mediated cleavage of messenger RNAs in mouse testes. Cell Res (2015) 1.13
Novel dimensions of piRNAs in cancer. Cancer Lett (2013) 1.13
Retrotransposons and pseudogenes regulate mRNAs and lncRNAs via the piRNA pathway in the germline. Genome Res (2014) 1.07
Defending the genome from the enemy within: mechanisms of retrotransposon suppression in the mouse germline. Cell Mol Life Sci (2013) 0.97
A comprehensive analysis of piRNAs from adult human testis and their relationship with genes and mobile elements. BMC Genomics (2014) 0.96
Small RNA profiling and characterization of piRNA clusters in the adult testes of the common marmoset, a model primate. RNA (2014) 0.96
piRNA-directed cleavage of meiotic transcripts regulates spermatogenesis. Genes Dev (2015) 0.93
Genome-wide analyses of Epstein-Barr virus reveal conserved RNA structures and a novel stable intronic sequence RNA. BMC Genomics (2013) 0.93
Identification and Functional Analysis of the Pre-piRNA 3' Trimmer in Silkworms. Cell (2016) 0.90
piRNAs derived from ancient viral processed pseudogenes as transgenerational sequence-specific immune memory in mammals. RNA (2015) 0.88
Aubergine iCLIP Reveals piRNA-Dependent Decay of mRNAs Involved in Germ Cell Development in the Early Embryo. Cell Rep (2015) 0.85
Regulation of spermatogenesis by small non-coding RNAs: role of the germ granule. Semin Cell Dev Biol (2014) 0.82
Conditional inactivation of Miwi2 reveals that MIWI2 is only essential for prospermatogonial development in mice. Cell Death Differ (2014) 0.82
piRNAQuest: searching the piRNAome for silencers. BMC Genomics (2014) 0.82
Tupaia small RNAs provide insights into function and evolution of RNAi-based transposon defense in mammals. RNA (2015) 0.82
A novel class of somatic small RNAs similar to germ cell pachytene PIWI-interacting small RNAs. J Biol Chem (2014) 0.81
Diversity and functional convergence of small noncoding RNAs in male germ cell differentiation and fertilization. RNA (2015) 0.81
Computer-assisted annotation of murine Sertoli cell small RNA transcriptome. Biol Reprod (2013) 0.81
Regulation of histone methylation by noncoding RNAs. Biochim Biophys Acta (2014) 0.81
RNF17 blocks promiscuous activity of PIWI proteins in mouse testes. Genes Dev (2015) 0.80
The spliceosome as a transposon sensor. RNA Biol (2013) 0.79
Non-coding RNA regulation of synaptic plasticity and memory: implications for aging. Ageing Res Rev (2014) 0.78
Profiling of the small RNA populations in human testicular germ cell tumors shows global loss of piRNAs. Mol Cancer (2015) 0.77
Argonaute2 Protein in Rat Spermatogenic Cells Is Localized to Nuage Structures and LAMP2-Positive Vesicles Surrounding Chromatoid Bodies. J Histochem Cytochem (2016) 0.76
Characterization of Sus scrofa small non-coding RNAs present in both female and male gonads. PLoS One (2014) 0.76
Piwi Proteins and piRNAs step onto the systems biology stage. Adv Exp Med Biol (2014) 0.76
Transposable Element Targeting by piRNAs in Laurasiatherians with Distinct Transposable Element Histories. Genome Biol Evol (2016) 0.76
Methylation of the Gpat2 promoter regulates transient expression during mouse spermatogenesis. Biochem J (2015) 0.75
Characterization of piRNAs across postnatal development in mouse brain. Sci Rep (2016) 0.75
An abundant class of tiny RNAs with probable regulatory roles in Caenorhabditis elegans. Science (2001) 44.16
Discrete small RNA-generating loci as master regulators of transposon activity in Drosophila. Cell (2007) 18.35
A slicer-mediated mechanism for repeat-associated siRNA 5' end formation in Drosophila. Science (2007) 10.73
A germline-specific class of small RNAs binds mammalian Piwi proteins. Nature (2006) 9.88
A novel class of small RNAs bind to MILI protein in mouse testes. Nature (2006) 8.80
Characterization of the piRNA complex from rat testes. Science (2006) 7.86
Developmentally regulated piRNA clusters implicate MILI in transposon control. Science (2007) 7.68
Specialized piRNA pathways act in germline and somatic tissues of the Drosophila ovary. Cell (2009) 6.39
A piRNA pathway primed by individual transposons is linked to de novo DNA methylation in mice. Mol Cell (2008) 6.35
A role for Piwi and piRNAs in germ cell maintenance and transposon silencing in Zebrafish. Cell (2007) 6.31
A novel class of small RNAs in mouse spermatogenic cells. Genes Dev (2006) 5.85
miwi, a murine homolog of piwi, encodes a cytoplasmic protein essential for spermatogenesis. Dev Cell (2002) 5.85
DNA methylation of retrotransposon genes is regulated by Piwi family members MILI and MIWI2 in murine fetal testes. Genes Dev (2008) 5.58
Mili, a mammalian member of piwi family gene, is essential for spermatogenesis. Development (2004) 5.47
The Drosophila RNA methyltransferase, DmHen1, modifies germline piRNAs and single-stranded siRNAs in RISC. Curr Biol (2007) 5.35
Identification and characterization of two novel classes of small RNAs in the mouse germline: retrotransposon-derived siRNAs in oocytes and germline small RNAs in testes. Genes Dev (2006) 4.97
Pimet, the Drosophila homolog of HEN1, mediates 2'-O-methylation of Piwi- interacting RNAs at their 3' ends. Genes Dev (2007) 4.68
Collapse of germline piRNAs in the absence of Argonaute3 reveals somatic piRNAs in flies. Cell (2009) 4.39
Biogenesis and germline functions of piRNAs. Development (2007) 4.37
The biogenesis and function of PIWI proteins and piRNAs: progress and prospect. Annu Rev Cell Dev Biol (2009) 3.21
Mouse Piwi-interacting RNAs are 2'-O-methylated at their 3' termini. Nat Struct Mol Biol (2007) 2.89
The 3' termini of mouse Piwi-interacting RNAs are 2'-O-methylated. Nat Struct Mol Biol (2007) 2.71
A broadly conserved pathway generates 3'UTR-directed primary piRNAs. Curr Biol (2009) 2.69
Loss of the Mili-interacting Tudor domain-containing protein-1 activates transposons and alters the Mili-associated small RNA profile. Nat Struct Mol Biol (2009) 2.64
Mili interacts with tudor domain-containing protein 1 in regulating spermatogenesis. Curr Biol (2009) 2.13
Uniting germline and stem cells: the function of Piwi proteins and the piRNA pathway in diverse organisms. Annu Rev Genet (2011) 2.07
Two mouse piwi-related genes: miwi and mili. Mech Dev (2001) 2.05
MILI, a PIWI-interacting RNA-binding protein, is required for germ line stem cell self-renewal and appears to positively regulate translation. J Biol Chem (2008) 1.93
Zili is required for germ cell differentiation and meiosis in zebrafish. EMBO J (2008) 1.87
2'-O-methylation stabilizes Piwi-associated small RNAs and ensures DNA elimination in Tetrahymena. RNA (2009) 1.76
A novel class of small RNAs in mouse spermatogenic cells. Genes Dev (2006) 5.85
miwi, a murine homolog of piwi, encodes a cytoplasmic protein essential for spermatogenesis. Dev Cell (2002) 5.85
Mili, a mammalian member of piwi family gene, is essential for spermatogenesis. Development (2004) 5.47
Three-dimensional, single-molecule fluorescence imaging beyond the diffraction limit by using a double-helix point spread function. Proc Natl Acad Sci U S A (2009) 4.29
MicroRNAs: key regulators of stem cells. Nat Rev Mol Cell Biol (2009) 4.26
[Smoking and passive smoking in Chinese, 2002]. Zhonghua Liu Xing Bing Xue Za Zhi (2005) 4.19
An epigenetic activation role of Piwi and a Piwi-associated piRNA in Drosophila melanogaster. Nature (2007) 3.86
Drosophila PIWI associates with chromatin and interacts directly with HP1a. Genes Dev (2007) 3.46
Two distinct mechanisms generate endogenous siRNAs from bidirectional transcription in Drosophila melanogaster. Nat Struct Mol Biol (2008) 3.40
Dynamic transcriptomes during neural differentiation of human embryonic stem cells revealed by short, long, and paired-end sequencing. Proc Natl Acad Sci U S A (2010) 3.28
The biogenesis and function of PIWI proteins and piRNAs: progress and prospect. Annu Rev Cell Dev Biol (2009) 3.21
The role of PIWI and the miRNA machinery in Drosophila germline determination. Curr Biol (2006) 3.06
Distinct mechanisms for microRNA strand selection by Drosophila Argonautes. Mol Cell (2009) 3.02
Genome-wide association study of esophageal squamous cell carcinoma in Chinese subjects identifies susceptibility loci at PLCE1 and C20orf54. Nat Genet (2010) 2.95
Evolutionary flux of canonical microRNAs and mirtrons in Drosophila. Nat Genet (2010) 2.84
MIWI associates with translational machinery and PIWI-interacting RNAs (piRNAs) in regulating spermatogenesis. Proc Natl Acad Sci U S A (2006) 2.80
Role for piRNAs and noncoding RNA in de novo DNA methylation of the imprinted mouse Rasgrf1 locus. Science (2011) 2.17
Mili interacts with tudor domain-containing protein 1 in regulating spermatogenesis. Curr Biol (2009) 2.13
Association of leptin with mortality in patients on maintenance hemodialysis: a prospective study. Iran J Kidney Dis (2014) 2.09
Uniting germline and stem cells: the function of Piwi proteins and the piRNA pathway in diverse organisms. Annu Rev Genet (2011) 2.07
Molecular characterization of hiwi, a human member of the piwi gene family whose overexpression is correlated to seminomas. Oncogene (2002) 2.03
MITOPLD is a mitochondrial protein essential for nuage formation and piRNA biogenesis in the mouse germline. Dev Cell (2011) 1.94
MILI, a PIWI-interacting RNA-binding protein, is required for germ line stem cell self-renewal and appears to positively regulate translation. J Biol Chem (2008) 1.93
Genome-wide studies reveal that Lin28 enhances the translation of genes important for growth and survival of human embryonic stem cells. Stem Cells (2011) 1.90
A major epigenetic programming mechanism guided by piRNAs. Dev Cell (2013) 1.89
Regulatory relationship among piwi, pumilio, and bag-of-marbles in Drosophila germline stem cell self-renewal and differentiation. Curr Biol (2005) 1.88
Sequential posttranslational modifications program FEN1 degradation during cell-cycle progression. Mol Cell (2012) 1.76
Nanos maintains germline stem cell self-renewal by preventing differentiation. Science (2004) 1.74
Expression of seven main Rho family members in gastric carcinoma. Biochem Biophys Res Commun (2004) 1.63
Drosophila Piwi functions in Hsp90-mediated suppression of phenotypic variation. Nat Genet (2010) 1.62
Human bocavirus in children hospitalized for acute gastroenteritis: a case-control study. Clin Infect Dis (2008) 1.61
Dicing of viral replication intermediates during silencing of latent Drosophila viruses. Proc Natl Acad Sci U S A (2009) 1.61
A photoactivatable push-pull fluorophore for single-molecule imaging in live cells. J Am Chem Soc (2008) 1.60
Genome-wide association analyses in Han Chinese identify two new susceptibility loci for amyotrophic lateral sclerosis. Nat Genet (2013) 1.57
Interplay of PIWI/Argonaute protein MIWI and kinesin KIF17b in chromatoid bodies of male germ cells. J Cell Sci (2006) 1.52
Reversal of multidrug resistance of gastric cancer cells by downregulation of TSG101 with TSG101siRNA. Cancer Biol Ther (2004) 1.51
Identification and nearly full-length genome characterization of novel porcine bocaviruses. PLoS One (2010) 1.51
Overexpression of ZNRD1 promotes multidrug-resistant phenotype of gastric cancer cells through upregulation of P-glycoprotein. Cancer Biol Ther (2004) 1.44
Candidate porcine Kobuvirus, China. Emerg Infect Dis (2009) 1.40
Transition from isolated to collective modes in plasmonic oligomers. Nano Lett (2010) 1.39
Correction of the Delta phe508 cystic fibrosis transmembrane conductance regulator trafficking defect by the bioavailable compound glafenine. Mol Pharmacol (2010) 1.36
Precancerous stem cells have the potential for both benign and malignant differentiation. PLoS One (2007) 1.36
Pumilio 1 suppresses multiple activators of p53 to safeguard spermatogenesis. Curr Biol (2012) 1.34
Piecing together the mosaic of early mammalian development through microRNAs. J Biol Chem (2008) 1.32
The Yb body, a major site for Piwi-associated RNA biogenesis and a gateway for Piwi expression and transport to the nucleus in somatic cells. J Biol Chem (2010) 1.30
The repression of human differentiation-related gene NDRG2 expression by Myc via Miz-1-dependent interaction with the NDRG2 core promoter. J Biol Chem (2006) 1.27
NDRG2 expression and mutation in human liver and pancreatic cancers. World J Gastroenterol (2004) 1.27
Enantioselective bromolactonization of conjugated (Z)-enynes. J Am Chem Soc (2010) 1.27
A high-resolution whole-genome map of key chromatin modifications in the adult Drosophila melanogaster. PLoS Genet (2011) 1.27
The Yb protein defines a novel organelle and regulates male germline stem cell self-renewal in Drosophila melanogaster. J Cell Biol (2009) 1.26
Structural analog of sildenafil identified as a novel corrector of the F508del-CFTR trafficking defect. Mol Pharmacol (2007) 1.25
NDRG2 is a new HIF-1 target gene necessary for hypoxia-induced apoptosis in A549 cells. Cell Physiol Biochem (2008) 1.24
Cellular prion protein promotes invasion and metastasis of gastric cancer. FASEB J (2006) 1.23
Tdrkh is essential for spermatogenesis and participates in primary piRNA biogenesis in the germline. EMBO J (2013) 1.22
Association of telomere length with authentic pluripotency of ES/iPS cells. Cell Res (2011) 1.22
Alternatively spliced human tissue factor promotes tumor growth and angiogenesis in a pancreatic cancer tumor model. Thromb Res (2007) 1.20
Piglets cloned from induced pluripotent stem cells. Cell Res (2012) 1.19
Hospital-Based Surveillance of Rotavirus Diarrhea in the People's Republic of China, August 2003-July 2007. J Infect Dis (2009) 1.19
Molecular insights into the heterogeneity of telomere reprogramming in induced pluripotent stem cells. Cell Res (2011) 1.18
Viral agents associated with acute gastroenteritis in children hospitalized with diarrhea in Lanzhou, China. J Clin Virol (2009) 1.18
Identification of Piwil2-like (PL2L) proteins that promote tumorigenesis. PLoS One (2010) 1.17
Overexpression and significance of prion protein in gastric cancer and multidrug-resistant gastric carcinoma cell line SGC7901/ADR. Int J Cancer (2005) 1.16
Beyond transposons: the epigenetic and somatic functions of the Piwi-piRNA mechanism. Curr Opin Cell Biol (2013) 1.16
Arginine methylation of hnRNP K enhances p53 transcriptional activity. FEBS Lett (2008) 1.15
Permanent Genetic Resources added to Molecular Ecology Resources Database 1 May 2009-31 July 2009. Mol Ecol Resour (2009) 1.15
Role of epidermal growth factor receptor in acute and chronic kidney injury. Kidney Int (2013) 1.14
Angiotensin II induces inflammatory response partly via toll-like receptor 4-dependent signaling pathway in vascular smooth muscle cells. Cell Physiol Biochem (2009) 1.14
DCDHF fluorophores for single-molecule imaging in cells. Chemphyschem (2009) 1.14
MiR-17 modulates osteogenic differentiation through a coherent feed-forward loop in mesenchymal stem cells isolated from periodontal ligaments of patients with periodontitis. Stem Cells (2011) 1.13
Two distinct mechanisms generate endogenous siRNAs from bidirectional transcription in Drosophila melanogaster. Nat Struct Mol Biol (2008) 1.13
Activation of transcription factor Nrf-2 and its downstream targets in response to moloney murine leukemia virus ts1-induced thiol depletion and oxidative stress in astrocytes. J Virol (2004) 1.13
Three-dimensional chiral plasmonic oligomers. Nano Lett (2012) 1.12
PAPI, a novel TUDOR-domain protein, complexes with AGO3, ME31B and TRAL in the nuage to silence transposition. Development (2011) 1.12
PPARgamma agonist, rosiglitazone, regulates angiotensin II-induced vascular inflammation through the TLR4-dependent signaling pathway. Lab Invest (2009) 1.11
Emergence of the GII4/2006b variant and recombinant noroviruses in China. J Med Virol (2008) 1.10
Human respiratory syncytial virus in children with acute respiratory tract infections in China. J Clin Microbiol (2010) 1.09
HFR1 sequesters PIF1 to govern the transcriptional network underlying light-initiated seed germination in Arabidopsis. Plant Cell (2013) 1.09
Palladium-based plasmonic perfect absorber in the visible wavelength range and its application to hydrogen sensing. Nano Lett (2011) 1.06
Notch1 is required for hypoxia-induced proliferation, invasion and chemoresistance of T-cell acute lymphoblastic leukemia cells. J Hematol Oncol (2013) 1.05
MiR-451 inhibits cell growth and invasion by targeting MIF and is associated with survival in nasopharyngeal carcinoma. Mol Cancer (2013) 1.05
Three-dimensional plasmonic chiral tetramers assembled by DNA origami. Nano Lett (2013) 1.04
Chronic fluoxetine treatment improves ischemia-induced spatial cognitive deficits through increasing hippocampal neurogenesis after stroke. J Neurosci Res (2009) 1.04
Hsa-miR-222 is involved in differentiation of endometrial stromal cells in vitro. Endocrinology (2009) 1.04
Plasmonic oligomers: the role of individual particles in collective behavior. ACS Nano (2011) 1.03
Generation of healthy mice from gene-corrected disease-specific induced pluripotent stem cells. PLoS Biol (2011) 1.02
Simultaneous detection of seven enteric viruses associated with acute gastroenteritis by a multiplexed Luminex-based assay. J Clin Microbiol (2012) 1.01
Sustained activation of EGFR triggers renal fibrogenesis after acute kidney injury. Am J Pathol (2013) 1.01
Azido push-pull fluorogens photoactivate to produce bright fluorescent labels. J Phys Chem B (2009) 1.01
Germline stem cells in the Drosophila ovary descend from pole cells in the anterior region of the embryonic gonad. Development (2004) 1.01
Function of Piwi, a nuclear Piwi/Argonaute protein, is independent of its slicer activity. Proc Natl Acad Sci U S A (2013) 1.00
Transplantation of parthenogenetic embryonic stem cells ameliorates cardiac dysfunction and remodelling after myocardial infarction. Cardiovasc Res (2012) 1.00
A distinct role of RhoB in gastric cancer suppression. Int J Cancer (2011) 0.99
Unprecedented 3D entanglement of 1D zigzag coordination polymers leading to a robust microporous framework. Chem Commun (Camb) (2006) 0.99
Akt1/protein kinase B alpha is involved in gastric cancer progression and cell proliferation. Dig Dis Sci (2008) 0.99
PIWI proteins and PIWI-interacting RNAs function in Hydra somatic stem cells. Proc Natl Acad Sci U S A (2013) 0.98
Histone deacetylase 1/2 mediates proliferation of renal interstitial fibroblasts and expression of cell cycle proteins. J Cell Biochem (2011) 0.98
High-efficiency siRNA-based gene knockdown in human embryonic stem cells. RNA (2010) 0.98