Published in Nature on July 15, 1976
Rous sarcoma virus genome is terminally redundant: the 5' sequence. Proc Natl Acad Sci U S A (1977) 7.09
Nucleotide sequence at the 5' terminus of the avian sarcoma virus genome. Proc Natl Acad Sci U S A (1977) 2.66
Nucleotide sequence relationships between the genomes of an endogenous and an exogenous avian tumor virus. J Virol (1978) 2.01
Terminal redundancy and the origin of replication of Rous sarcoma virus RNA. Proc Natl Acad Sci U S A (1977) 1.94
In vitro synthesis of a unique RNA species by a T particle of vesicular stomatitis virus. J Virol (1977) 1.89
Equine infectious anemia virus and human immunodeficiency virus DNA synthesis in vitro: characterization of the endogenous reverse transcriptase reaction. J Virol (1991) 1.71
Unwinding-like activity associated with avian retrovirus RNA-directed DNA polymerase. J Virol (1978) 1.59
Terminally repeated sequences in the avian sarcoma virus RNA genome. Proc Natl Acad Sci U S A (1977) 1.58
Extensive in vitro transcription of rous sarcoma virus RNA by avian myeloblastosis virus DNA polymerase and concurrent activation of the associated RNase H. J Virol (1977) 1.52
New procedure for the direct analysis of in vitro reverse transcription of Rous sarcoma virus RNA. J Virol (1977) 1.29
Evidence for splicing of avian sarcoma virus 5'-terminal genomic sequences into viral-specific RNA in infected cells. Proc Natl Acad Sci U S A (1978) 1.24
In vitro transcription of theavian oncornavirus genome by the RNA-directed DNA polymerase: analysis of DNA transcripts synthesized in reconstructed enzymatic reactions. J Virol (1977) 1.08
Elongation of DNA complementary to the 5' end of the avian sarcoma virus genome by the virion-associated RNA-dependent DNA polymerase. J Virol (1979) 0.98
5'-terminal nucleotide sequences of mammalian type C helper viruses are conserved in the genomes of replication-defective mammalian transforming viruses. J Virol (1978) 0.92
Deletion mutant of the Bratislava-77 strain of Rous sarcoma virus containing a fusion of the group-specific antigen and envelope genes. J Virol (1979) 0.90
Primer recognition by avian myeloblastosis virus RNA-directed DNA polymerase. J Virol (1977) 0.82
Initiation of DNA synthesis by the avian retrovirus reverse transcriptase in vitro: nature and location of the oligodeoxycytidylic acid primer binding site. J Virol (1979) 0.75
A rapid, sensitive, and specific method for the determination of protein in dilute solution. Anal Biochem (1973) 31.32
Mapping of RNA by a modification of the Berk-Sharp procedure: the 5' termini of 15 S beta-globin mRNA precursor and mature 10 s beta-globin mRNA have identical map coordinates. Nucleic Acids Res (1979) 31.23
Mice devoid of PrP are resistant to scrapie. Cell (1993) 11.46
Three regions upstream from the cap site are required for efficient and accurate transcription of the rabbit beta-globin gene in mouse 3T6 cells. Cell (1983) 9.51
Normal development and behaviour of mice lacking the neuronal cell-surface PrP protein. Nature (1992) 9.01
Rescue of measles viruses from cloned DNA. EMBO J (1995) 7.87
Comparison of total sequence of a cloned rabbit beta-globin gene and its flanking regions with a homologous mouse sequence. Science (1979) 6.94
Deficient signaling in mice devoid of double-stranded RNA-dependent protein kinase. EMBO J (1995) 6.94
Prion protein (PrP) with amino-proximal deletions restoring susceptibility of PrP knockout mice to scrapie. EMBO J (1996) 6.66
The intervening sequence of a mouse beta-globin gene is transcribed within the 15S beta-globin mRNA precursor. Proc Natl Acad Sci U S A (1978) 6.20
Hybrid plasmids containing an active thymidine kinase gene of Herpes simplex virus 1. Nucleic Acids Res (1979) 5.55
Nucleotide sequence heterogeneity of an RNA phage population. Cell (1978) 5.55
A minimal intron length but no specific internal sequence is required for splicing the large rabbit beta-globin intron. Cell (1984) 5.37
DNA sequences preceding the rabbit beta-globin gene are required for formation in mouse L cells of beta-globin RNA with the correct 5' terminus. Proc Natl Acad Sci U S A (1981) 5.26
Mx protein: constitutive expression in 3T3 cells transformed with cloned Mx cDNA confers selective resistance to influenza virus. Cell (1986) 4.92
Biased hypermutation and other genetic changes in defective measles viruses in human brain infections. Cell (1988) 4.90
The nucleotide sequence complexity of avian tumor virus RNA. Proc Natl Acad Sci U S A (1974) 4.86
The structure of one of the eight or more distinct chromosomal genes for human interferon-alpha. Nature (1980) 4.82
Scrapie and cellular PrP isoforms are encoded by the same chromosomal gene. Cell (1986) 4.82
A physical map of the Rous sarcoma virus genome. J Mol Biol (1976) 4.56
Sequence requirements for splicing of higher eukaryotic nuclear pre-mRNA. Cell (1986) 4.40
Unusual splice sites revealed by mutagenic inactivation of an authentic splice site of the rabbit beta-globin gene. Nature (1983) 4.38
Normal host prion protein necessary for scrapie-induced neurotoxicity. Nature (1996) 4.25
Mapping of biological functions on RNA of avian tumor viruses: location of regions required for transformation and determination of host range. Proc Natl Acad Sci U S A (1975) 4.01
A novel potassium channel with delayed rectifier properties isolated from rat brain by expression cloning. Nature (1989) 3.99
A double-stranded RNA-activated protein kinase-dependent pathway mediating stress-induced apoptosis. Proc Natl Acad Sci U S A (1997) 3.88
Rabbit beta-globin mRNA production in mouse L cells transformed with cloned rabbit beta-globin chromosomal DNA. Nature (1979) 3.88
Comparison of cloned rabbit and mouse beta-globin genes showing strong evolutionary divergence of two homologous pairs of introns. Nature (1978) 3.86
Specific excision of the inserted DNA segment from hybrid plasmids constructed by the poly(dA). poly (dT) method. Biochim Biophys Acta (1976) 3.79
Induction of mRNA for a serine protease and a beta-thromboglobulin-like protein in mitogen-stimulated human leukocytes. J Immunol (1987) 3.78
Synthesis in E. coli of a polypeptide with human leukocyte interferon activity. Nature (1980) 3.78
Expression of amino-terminally truncated PrP in the mouse leading to ataxia and specific cerebellar lesions. Cell (1998) 3.59
Human leukocyte and fibroblast interferons are structurally related. Nature (1980) 3.57
Deficient cytokine signaling in mouse embryo fibroblasts with a targeted deletion in the PKR gene: role of IRF-1 and NF-kappaB. EMBO J (1997) 3.34
Measles virus editing provides an additional cysteine-rich protein. Cell (1989) 3.22
Organization of the murine Mx gene and characterization of its interferon- and virus-inducible promoter. Mol Cell Biol (1988) 3.19
QB DNA-containing hybrid plasmids giving rise to QB phage formation in the bacterial host. Nature (1978) 3.11
Exchange of conduction pathways between two related K+ channels. Science (1991) 3.09
The isolation of plasmids containing DNA complementary to messenger RNA for variant surface glycoproteins of Trypanosoma brucei. Gene (1980) 2.99
A quantitative, highly sensitive cell-based infectivity assay for mouse scrapie prions. Proc Natl Acad Sci U S A (2003) 2.94
Infectivity in mouse fibroblasts of polyoma DNA integrated into plasmid pBR322 or lambdoid phage DNA. Nature (1979) 2.92
Localization of Q-beta maturation cistron ribosome binding site. Nat New Biol (1971) 2.91
The proportion of revertant and mutant phage in a growing population, as a function of mutation and growth rate. Gene (1976) 2.77
5' cleavage site in eukaryotic pre-mRNA splicing is determined by the overall 5' splice region, not by the conserved 5' GU. Cell (1987) 2.69
Altered transcription of a defective measles virus genome derived from a diseased human brain. EMBO J (1987) 2.67
A 46-nucleotide promoter segment from an IFN-alpha gene renders an unrelated promoter inducible by virus. Cell (1985) 2.65
Avian myeloblastosis virus RNA is terminally redundant: implications for the mechanism of retrovirus replication. Cell (1977) 2.55
Biased hypermutation of viral RNA genomes could be due to unwinding/modification of double-stranded RNA. Cell (1989) 2.54
Scrapie prion protein accumulation by scrapie-infected neuroblastoma cells abrogated by exposure to a prion protein antibody. Proc Natl Acad Sci U S A (2001) 2.53
The nucleotide sequence of a cloned human leukocyte interferon cDNA. Gene (1980) 2.51
Structure and function of phage RNA. Annu Rev Biochem (1973) 2.50
A matrix-less measles virus is infectious and elicits extensive cell fusion: consequences for propagation in the brain. EMBO J (1998) 2.48
Replication of viral ribonucleic acid. IX. Properties of double-stranded RNA from Escherichia coli infected with bacteriophage MS2. J Mol Biol (1966) 2.45
Quantitative determination and location of newly synthesized virus-specific ribonucleic acid in chicken cells infected with Rous sarcoma virus. J Virol (1973) 2.45
PrP expression in B lymphocytes is not required for prion neuroinvasion. Nat Med (1998) 2.40
At least three human type alpha interferons: structure of alpha 2. Science (1980) 2.38
Retracted Infectious measles virus from cloned cDNA. EMBO J (1990) 2.36
Structure and expression of cloned murine IFN-alpha genes. Nucleic Acids Res (1983) 2.35
Observation of measles virus cell-to-cell spread in astrocytoma cells by using a green fluorescent protein-expressing recombinant virus. J Virol (1999) 2.34
Subunit structure of Q-beta replicase. Nature (1970) 2.30
Mice devoid of interferon regulatory factor 1 (IRF-1) show normal expression of type I interferon genes. EMBO J (1994) 2.27
Alteration and restoration of K+ channel function by deletions at the N- and C-termini. Neuron (1990) 2.26
High prion and PrPSc levels but delayed onset of disease in scrapie-inoculated mice heterozygous for a disrupted PrP gene. Mol Med (1994) 2.18
Site-directed mutagenesis in DNA: generation of point mutations in cloned beta globin complementary dna at the positions corresponding to amino acids 121 to 123. J Mol Biol (1978) 2.17
Impaired prion replication in spleens of mice lacking functional follicular dendritic cells. Science (2000) 2.15
Prion research: the next frontiers. Nature (1997) 2.13
Prion protein devoid of the octapeptide repeat region restores susceptibility to scrapie in PrP knockout mice. Neuron (2000) 2.13
Effect of mutations at the lariat branch acceptor site on beta-globin pre-mRNA splicing in vitro. Nature (1987) 2.11
Rescue of synthetic measles virus minireplicons: measles genomic termini direct efficient expression and propagation of a reporter gene. Virology (1995) 2.11
Possible origin of a minor virus specific protein (A1) in Q-beta particles. Nat New Biol (1971) 2.09
Characterization and kinetics of synthesis of 15S beta-globin RNA, a putative precursor of beta-globin mRNA. Cold Spring Harb Symp Quant Biol (1978) 2.08
PrP-expressing tissue required for transfer of scrapie infectivity from spleen to brain. Nature (1997) 2.08
Side-chain accessibilities in the pore of a K+ channel probed by sulfhydryl-specific reagents after cysteine-scanning mutagenesis. Biophys J (1995) 2.06
No propagation of prions in mice devoid of PrP. Cell (1994) 2.02
Evidence against a scanning model of RNA splicing. EMBO J (1983) 2.01
Recombinant measles viruses defective for RNA editing and V protein synthesis are viable in cultured cells. Virology (1997) 2.01
The nonstructural C protein is not essential for multiplication of Edmonston B strain measles virus in cultured cells. Virology (1996) 1.95
Purification of globin messenger RNA from dimethylsulfoxide-induced Friend cells and detection of a putative globin messenger RNA precursor. J Mol Biol (1976) 1.92
Target cell specificity of two species of human interferon-alpha produced in Escherichia coli and of hybrid molecules derived from them. Proc Natl Acad Sci U S A (1981) 1.89
Interaction of measles virus glycoproteins with the surface of uninfected peripheral blood lymphocytes induces immunosuppression in vitro. Proc Natl Acad Sci U S A (1996) 1.89
Reconstitution of Q replicase lacking subunit with protein-synthesis-interference factor i. Eur J Biochem (1972) 1.88
Reversible silencing of enhancers by sequences derived from the human IFN-alpha promoter. Cell (1987) 1.87
The interferon genes. Prog Nucleic Acid Res Mol Biol (1986) 1.85
Onset of ataxia and Purkinje cell loss in PrP null mice inversely correlated with Dpl level in brain. EMBO J (2001) 1.85
Sequence of the first 175 nucleotides from the 5' terminus of Qbeta RNA synthesized in vitro. Nature (1969) 1.84
Multiple viral mutations rather than host factors cause defective measles virus gene expression in a subacute sclerosing panencephalitis cell line. J Virol (1988) 1.84
Abnormal expression of chromosomal rabbit beta-globin gene in Saccharomyces cerevisiae. Nature (1980) 1.84
Differential expression of human interferon genes. Nucleic Acids Res (1984) 1.82
Nonconsensus branch-site sequences in the in vitro splicing of transcripts of mutant rabbit beta-globin genes. Proc Natl Acad Sci U S A (1985) 1.82
Retracted Functional and nonfunctional measles virus matrix genes from lethal human brain infections. J Virol (1991) 1.82
Inhibition of Qbeta RNA 70S ribosome initiation complex formation by an oligonucleotide complementary to the 3' terminal region of E. coli 16S ribosomal RNA. Nature (1978) 1.81
Ectopic expression of prion protein (PrP) in T lymphocytes or hepatocytes of PrP knockout mice is insufficient to sustain prion replication. Proc Natl Acad Sci U S A (1999) 1.81
Studies on the structure and synthesis of Rous sarcoma virus RNA. Cold Spring Harb Symp Quant Biol (1975) 1.80