Argonaute proteins: key players in RNA silencing.

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RNA-guided RNA cleavage by a CRISPR RNA-Cas protein complex. Cell (2009) 11.12

A dicer-independent miRNA biogenesis pathway that requires Ago catalysis. Nature (2010) 6.37

A three-dimensional view of the molecular machinery of RNA interference. Nature (2009) 6.31

Structure of an argonaute silencing complex with a seed-containing guide DNA and target RNA duplex. Nature (2008) 5.78

Extensive and coordinated transcription of noncoding RNAs within cell-cycle promoters. Nat Genet (2011) 5.62

Structure of the guide-strand-containing argonaute silencing complex. Nature (2008) 5.36

Nucleation, propagation and cleavage of target RNAs in Ago silencing complexes. Nature (2009) 5.24

PRG-1 and 21U-RNAs interact to form the piRNA complex required for fertility in C. elegans. Mol Cell (2008) 4.48

HuR recruits let-7/RISC to repress c-Myc expression. Genes Dev (2009) 4.41

On the road to reading the RNA-interference code. Nature (2009) 4.33

Small RNAs and their roles in plant development. Annu Rev Cell Dev Biol (2009) 4.32

Small RNA sorting: matchmaking for Argonautes. Nat Rev Genet (2010) 4.27

Filtering of deep sequencing data reveals the existence of abundant Dicer-dependent small RNAs derived from tRNAs. RNA (2009) 3.87

Structural basis for 5'-nucleotide base-specific recognition of guide RNA by human AGO2. Nature (2010) 3.77

Structure and mechanism of the CMR complex for CRISPR-mediated antiviral immunity. Mol Cell (2012) 3.41

Argonaute proteins: functional insights and emerging roles. Nat Rev Genet (2013) 3.09

Small RNAs derived from snoRNAs. RNA (2009) 3.04

A novel family of sequence-specific endoribonucleases associated with the clustered regularly interspaced short palindromic repeats. J Biol Chem (2008) 3.00

Dicer-independent primal RNAs trigger RNAi and heterochromatin formation. Cell (2010) 2.99

Proteomic analysis of murine Piwi proteins reveals a role for arginine methylation in specifying interaction with Tudor family members. Genes Dev (2009) 2.95

A comprehensive survey of 3' animal miRNA modification events and a possible role for 3' adenylation in modulating miRNA targeting effectiveness. Genome Res (2010) 2.87

Role of miRNAs and siRNAs in biotic and abiotic stress responses of plants. Biochim Biophys Acta (2011) 2.84

The Argonaute protein family. Genome Biol (2008) 2.83

Essential and overlapping functions for mammalian Argonautes in microRNA silencing. Genes Dev (2009) 2.73

Distinct phases of siRNA synthesis in an endogenous RNAi pathway in C. elegans soma. Mol Cell (2010) 2.57

Potential role of miR-9 and miR-223 in recurrent ovarian cancer. Mol Cancer (2008) 2.53

MicroRNAs and cardiac pathology. Nat Rev Cardiol (2009) 2.50

CRD-BP protects the coding region of betaTrCP1 mRNA from miR-183-mediated degradation. Mol Cell (2009) 2.38

Ars2 regulates both miRNA- and siRNA- dependent silencing and suppresses RNA virus infection in Drosophila. Cell (2009) 2.38

The evolution of RNAi as a defence against viruses and transposable elements. Philos Trans R Soc Lond B Biol Sci (2009) 2.35

Piwi induces piRNA-guided transcriptional silencing and establishment of a repressive chromatin state. Genes Dev (2013) 2.34

The mammalian ovary from genesis to revelation. Endocr Rev (2009) 2.31

Regulation of MicroRNA Biogenesis: A miRiad of mechanisms. Cell Commun Signal (2009) 2.27

Enhancement of the seed-target recognition step in RNA silencing by a PIWI/MID domain protein. Mol Cell (2009) 2.27

Existence of a microRNA pathway in anucleate platelets. Nat Struct Mol Biol (2009) 2.26

Deep-sequencing of human Argonaute-associated small RNAs provides insight into miRNA sorting and reveals Argonaute association with RNA fragments of diverse origin. RNA Biol (2011) 2.18

A multifunctional human Argonaute2-specific monoclonal antibody. RNA (2008) 2.17

Origins and evolution of eukaryotic RNA interference. Trends Ecol Evol (2008) 2.15

ATP-dependent human RISC assembly pathways. Nat Struct Mol Biol (2009) 2.04

Arabidopsis Argonaute 2 regulates innate immunity via miRNA393(∗)-mediated silencing of a Golgi-localized SNARE gene, MEMB12. Mol Cell (2011) 2.01

Targeting miRNAs involved in cancer stem cell and EMT regulation: An emerging concept in overcoming drug resistance. Drug Resist Updat (2010) 1.98

The impact of disparate isolation methods for extracellular vesicles on downstream RNA profiling. J Extracell Vesicles (2014) 1.92

Form, function, and regulation of ARGONAUTE proteins. Plant Cell (2010) 1.87

The take and give between retrotransposable elements and their hosts. Annu Rev Genet (2008) 1.86

Argonautes ALG-3 and ALG-4 are required for spermatogenesis-specific 26G-RNAs and thermotolerant sperm in Caenorhabditis elegans. Proc Natl Acad Sci U S A (2010) 1.81

Distinct passenger strand and mRNA cleavage activities of human Argonaute proteins. Nat Struct Mol Biol (2009) 1.81

Involvement of argonaute proteins in gene silencing and activation by RNAs complementary to a non-coding transcript at the progesterone receptor promoter. Nucleic Acids Res (2010) 1.74

Mouse Piwi interactome identifies binding mechanism of Tdrkh Tudor domain to arginine methylated Miwi. Proc Natl Acad Sci U S A (2009) 1.73

How does the royal family of Tudor rule the PIWI-interacting RNA pathway? Genes Dev (2010) 1.71

Microarray analysis of the abscission-related transcriptome in the tomato flower abscission zone in response to auxin depletion. Plant Physiol (2010) 1.70

Deciphering arginine methylation: Tudor tells the tale. Nat Rev Mol Cell Biol (2011) 1.69

Gene silencing in the marine diatom Phaeodactylum tricornutum. Nucleic Acids Res (2009) 1.67

Production of viable gametes without meiosis in maize deficient for an ARGONAUTE protein. Plant Cell (2011) 1.67

microRNAs associated with the different human Argonaute proteins. Nucleic Acids Res (2012) 1.66

Degradation of the antiviral component ARGONAUTE1 by the autophagy pathway. Proc Natl Acad Sci U S A (2012) 1.62

CapSeq and CIP-TAP identify Pol II start sites and reveal capped small RNAs as C. elegans piRNA precursors. Cell (2012) 1.61

Hormonal regulation of MicroRNA expression in periovulatory mouse mural granulosa cells. Biol Reprod (2008) 1.61

Hsp90 regulates the function of argonaute 2 and its recruitment to stress granules and P-bodies. Mol Biol Cell (2009) 1.60

Human liver stem cell-derived microvesicles accelerate hepatic regeneration in hepatectomized rats. J Cell Mol Med (2009) 1.58

Characterization of the miRNA-RISC loading complex and miRNA-RISC formed in the Drosophila miRNA pathway. RNA (2009) 1.55

The N domain of Argonaute drives duplex unwinding during RISC assembly. Nat Struct Mol Biol (2012) 1.55

miR-107 regulates granulin/progranulin with implications for traumatic brain injury and neurodegenerative disease. Am J Pathol (2010) 1.54

Increased RNA-induced silencing complex (RISC) activity contributes to hepatocellular carcinoma. Hepatology (2011) 1.54

Epigenetic principles and mechanisms underlying nervous system functions in health and disease. Prog Neurobiol (2008) 1.53

HP1 recruitment in the absence of argonaute proteins in Drosophila. PLoS Genet (2010) 1.53

Hen1 is required for oocyte development and piRNA stability in zebrafish. EMBO J (2010) 1.53

Biogenic mechanisms and utilization of small RNAs derived from human protein-coding genes. Nat Struct Mol Biol (2011) 1.51

Emerging roles of microRNAs as molecular switches in the integrated circuit of the cancer cell. RNA (2009) 1.48

Many ways to generate microRNA-like small RNAs: non-canonical pathways for microRNA production. Mol Genet Genomics (2010) 1.48

Mechanisms of control of microRNA biogenesis. J Biochem (2010) 1.48

Anti-Argonaute RIP-Chip shows that miRNA transfections alter global patterns of mRNA recruitment to microribonucleoprotein complexes. RNA (2009) 1.45

Extracellular/circulating microRNAs and their potential role in cardiovascular disease. Am J Cardiovasc Dis (2011) 1.43

Gene expression and stress response mediated by the epigenetic regulation of a transposable element small RNA. PLoS Genet (2012) 1.43

The whole genome sequence of the Mediterranean fruit fly, Ceratitis capitata (Wiedemann), reveals insights into the biology and adaptive evolution of a highly invasive pest species. Genome Biol (2016) 1.42

GW182-Free microRNA Silencing Complex Controls Post-transcriptional Gene Expression during Caenorhabditis elegans Embryogenesis. PLoS Genet (2016) 1.41

Structure of Arabidopsis HYPONASTIC LEAVES1 and its molecular implications for miRNA processing. Structure (2010) 1.41

The evolutionary journey of Argonaute proteins. Nat Struct Mol Biol (2014) 1.41

Structural basis for piRNA 2'-O-methylated 3'-end recognition by Piwi PAZ (Piwi/Argonaute/Zwille) domains. Proc Natl Acad Sci U S A (2010) 1.40

AGO1 homeostasis involves differential production of 21-nt and 22-nt miR168 species by MIR168a and MIR168b. PLoS One (2009) 1.40

Distinct AGO1 and AGO2 associated miRNA profiles in human cells and blood plasma. RNA Biol (2012) 1.38

Dogma derailed: the many influences of RNA on the genome. Mol Cell (2013) 1.36

The stem cell-associated Hiwi gene in human adenocarcinoma of the pancreas: expression and risk of tumour-related death. Br J Cancer (2008) 1.36

RDE-1 slicer activity is required only for passenger-strand cleavage during RNAi in Caenorhabditis elegans. Nat Struct Mol Biol (2009) 1.35

Therapeutic siRNA: principles, challenges, and strategies. Yale J Biol Med (2012) 1.35

From snoRNA to miRNA: Dual function regulatory non-coding RNAs. Biochimie (2011) 1.35

CAMTA1 is a novel tumour suppressor regulated by miR-9/9* in glioblastoma stem cells. EMBO J (2011) 1.32

Innate antiviral immunity in Drosophila. Curr Opin Immunol (2010) 1.30

An inside job for siRNAs. Mol Cell (2008) 1.29

A Caenorhabditis elegans RNA-directed RNA polymerase in sperm development and endogenous RNA interference. Genetics (2009) 1.28

Structural and functional analysis of viral siRNAs. PLoS Pathog (2010) 1.28

Deep annotation of mouse iso-miR and iso-moR variation. Nucleic Acids Res (2012) 1.27

microRNAs in heart disease: putative novel therapeutic targets? Eur Heart J (2010) 1.27

Plant responses against invasive nucleic acids: RNA silencing and its suppression by plant viral pathogens. Semin Cell Dev Biol (2009) 1.26

Structure-based cleavage mechanism of Thermus thermophilus Argonaute DNA guide strand-mediated DNA target cleavage. Proc Natl Acad Sci U S A (2013) 1.26

Viral protein inhibits RISC activity by argonaute binding through conserved WG/GW motifs. PLoS Pathog (2010) 1.26

MicroRNA processing pathway regulates olfactory neuron morphogenesis. Curr Biol (2008) 1.25

Kaposi's sarcoma-associated herpesvirus ORF57 promotes escape of viral and human interleukin-6 from microRNA-mediated suppression. J Virol (2011) 1.25

IL-10-induced microRNA-187 negatively regulates TNF-α, IL-6, and IL-12p40 production in TLR4-stimulated monocytes. Proc Natl Acad Sci U S A (2012) 1.24

mut-16 and other mutator class genes modulate 22G and 26G siRNA pathways in Caenorhabditis elegans. Proc Natl Acad Sci U S A (2011) 1.23

Sequence-specific inhibition of small RNA function. PLoS Biol (2004) 7.98

Analysis of the C. elegans Argonaute family reveals that distinct Argonautes act sequentially during RNAi. Cell (2006) 7.14

Human let-7a miRNA blocks protein production on actively translating polyribosomes. Nat Struct Mol Biol (2006) 4.67

Role for miR-204 in human pulmonary arterial hypertension. J Exp Med (2011) 2.60

A member of the polymerase beta nucleotidyltransferase superfamily is required for RNA interference in C. elegans. Curr Biol (2005) 1.61

Two molecular features contribute to the Argonaute specificity for the microRNA and RNAi pathways in C. elegans. RNA (2008) 1.22

The decapping scavenger enzyme DCS-1 controls microRNA levels in Caenorhabditis elegans. Mol Cell (2013) 1.13

The ribosomal protein RACK1 is required for microRNA function in both C. elegans and humans. EMBO Rep (2011) 1.07

Annexin-1-mediated endothelial cell migration and angiogenesis are regulated by vascular endothelial growth factor (VEGF)-induced inhibition of miR-196a expression. J Biol Chem (2012) 0.99

Developmental characterization of the microRNA-specific C. elegans Argonautes alg-1 and alg-2. PLoS One (2012) 0.96

The slicing activity of miRNA-specific Argonautes is essential for the miRNA pathway in C. elegans. Nucleic Acids Res (2012) 0.91

The microRNA pathway controls germ cell proliferation and differentiation in C. elegans. Cell Res (2012) 0.91

RIP-chip-SRM--a new combinatorial large-scale approach identifies a set of translationally regulated bantam/miR-58 targets in C. elegans. Genome Res (2012) 0.85

miR-20a represses endothelial cell migration by targeting MKK3 and inhibiting p38 MAP kinase activation in response to VEGF. Angiogenesis (2012) 0.84

Argonaute pull-down and RISC analysis using 2'-O-methylated oligonucleotides affinity matrices. Methods Mol Biol (2011) 0.83

Structural biology: Tracing Argonaute binding. Nature (2009) 0.83

Polypyrimidine tract binding protein (hnRNP I) is possibly a conserved modulator of miRNA-mediated gene regulation. PLoS One (2012) 0.82

Novel features of a PIWI-like protein homolog in the parasitic protozoan Leishmania. PLoS One (2012) 0.82

Next-generation biobanking of metastases to enable multidimensional molecular profiling in personalized medicine. Mod Pathol (2013) 0.82

RNAi pathway in C. elegans: the argonautes and collaborators. Curr Top Microbiol Immunol (2008) 0.82

Down regulation of miR-124 in both Werner syndrome DNA helicase mutant mice and mutant Caenorhabditis elegans wrn-1 reveals the importance of this microRNA in accelerated aging. Aging (Albany NY) (2012) 0.82

Expression profile of Caenorhabditis elegans mutant for the Werner syndrome gene ortholog reveals the impact of vitamin C on development to increase life span. BMC Genomics (2014) 0.79

A new role for the GARP complex in microRNA-mediated gene regulation. PLoS Genet (2013) 0.77

A new twist in the microRNA pathway: Not Dicer but Argonaute is required for a microRNA production. Cell Res (2010) 0.76

The decapping scavenger enzyme DCS-1: a new modulator of miRNA turnover. Cell Cycle (2013) 0.75

Correction: GW182-Free microRNA Silencing Complex Controls Post-transcriptional Gene Expression during Caenorhabditis elegans Embryogenesis. PLoS Genet (2016) 0.75