Published in PLoS Biol on February 24, 2004
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MicroRNA-21 targets Sprouty2 and promotes cellular outgrowths. Mol Biol Cell (2008) 3.10
Targeted inhibition of miRNA maturation with morpholinos reveals a role for miR-375 in pancreatic islet development. PLoS Biol (2007) 3.04
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A feedback regulatory loop involving microRNA-9 and nuclear receptor TLX in neural stem cell fate determination. Nat Struct Mol Biol (2009) 2.96
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Small RNA-mediated regulation of iPS cell generation. EMBO J (2011) 2.95
Zcchc11-dependent uridylation of microRNA directs cytokine expression. Nat Cell Biol (2009) 2.63
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Predicting and validating microRNA targets. Genome Biol (2004) 2.54
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MicroRNA miR-124 regulates neurite outgrowth during neuronal differentiation. Exp Cell Res (2008) 2.46
Transforming growth factor-beta-regulated miR-24 promotes skeletal muscle differentiation. Nucleic Acids Res (2008) 2.44
Tandem array-based expression screens identify host mRNA targets of virus-encoded microRNAs. Nat Genet (2008) 2.42
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MicroRNA regulation of cyclooxygenase-2 during embryo implantation. Proc Natl Acad Sci U S A (2007) 2.16
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Targeting miRNAs involved in cancer stem cell and EMT regulation: An emerging concept in overcoming drug resistance. Drug Resist Updat (2010) 1.98
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miR-17 and miR-20a temper an E2F1-induced G1 checkpoint to regulate cell cycle progression. Oncogene (2008) 1.86
Double-stranded regions are essential design components of potent inhibitors of RISC function. RNA (2007) 1.83
A small molecule enhances RNA interference and promotes microRNA processing. Nat Biotechnol (2008) 1.80
MicroRNAs as Novel Biomarkers for Breast Cancer. J Oncol (2009) 1.72
Long-term, efficient inhibition of microRNA function in mice using rAAV vectors. Nat Methods (2012) 1.67
A single female-specific piRNA is the primary determiner of sex in the silkworm. Nature (2014) 1.63
MicroRNA-binding viral protein interferes with Arabidopsis development. Proc Natl Acad Sci U S A (2005) 1.62
Implication of microRNAs in drug resistance for designing novel cancer therapy. Drug Resist Updat (2010) 1.61
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The role of microRNAs in cancer. Yale J Biol Med (2006) 1.54
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Functional screening identifies miR-315 as a potent activator of Wingless signaling. Proc Natl Acad Sci U S A (2007) 1.53
Developing therapeutic microRNAs for cancer. Gene Ther (2011) 1.49
Sequence relationships among C. elegans, D. melanogaster and human microRNAs highlight the extensive conservation of microRNAs in biology. PLoS One (2008) 1.49
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microRNA miR-275 is indispensable for blood digestion and egg development in the mosquito Aedes aegypti. Proc Natl Acad Sci U S A (2010) 1.43
Small RNAs derived from the 5' end of tRNA can inhibit protein translation in human cells. RNA Biol (2013) 1.43
microRNAs: a new emerging class of players for disease diagnostics and gene therapy. J Cell Mol Med (2007) 1.43
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Regulation of microRNAs by natural agents: an emerging field in chemoprevention and chemotherapy research. Pharm Res (2010) 1.40
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MicroRNAs in neurodegenerative diseases and their therapeutic potential. Pharmacol Ther (2011) 1.37
MicroRNAs: regulating a change of heart. Circulation (2009) 1.37
Site-specific crosslinking of human microRNPs to RNA targets. RNA (2008) 1.35
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MicroRNAs transfer from human macrophages to hepato-carcinoma cells and inhibit proliferation. J Immunol (2013) 1.34
Effect of adenovirus-mediated RNA interference on endogenous microRNAs in a mouse model of multidrug resistance protein 2 gene silencing. J Virol (2006) 1.32
The let-7 microRNA target gene, Mlin41/Trim71 is required for mouse embryonic survival and neural tube closure. Cell Cycle (2008) 1.32
MicroRNAs in ovarian carcinomas. Endocr Relat Cancer (2010) 1.25
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Dissecting systemic RNA interference in the red flour beetle Tribolium castaneum: parameters affecting the efficiency of RNAi. PLoS One (2012) 1.23
Two molecular features contribute to the Argonaute specificity for the microRNA and RNAi pathways in C. elegans. RNA (2008) 1.22
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PAI-1-regulated miR-21 defines a novel age-associated fibrogenic pathway in muscular dystrophy. J Cell Biol (2012) 1.18
MicroRNAs in cancer treatment and prognosis. Am J Cancer Res (2012) 1.17
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The decapping scavenger enzyme DCS-1 controls microRNA levels in Caenorhabditis elegans. Mol Cell (2013) 1.13
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Rational design leads to more potent RNA interference against hepatitis B virus: factors effecting silencing efficiency. Mol Ther (2008) 1.10
MicroRNA in central nervous system trauma and degenerative disorders. Physiol Genomics (2011) 1.10
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The ribosomal protein RACK1 is required for microRNA function in both C. elegans and humans. EMBO Rep (2011) 1.07
MiR-133b targets antiapoptotic genes and enhances death receptor-induced apoptosis. PLoS One (2012) 1.06
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An ancient transcription factor initiates the burst of piRNA production during early meiosis in mouse testes. Mol Cell (2013) 2.23
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Five siRNAs targeting three SNPs may provide therapy for three-quarters of Huntington's disease patients. Curr Biol (2009) 2.19
Argonaute divides its RNA guide into domains with distinct functions and RNA-binding properties. Cell (2012) 2.07
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Selective silencing by RNAi of a dominant allele that causes amyotrophic lateral sclerosis. Aging Cell (2003) 1.88
Argonautes ALG-3 and ALG-4 are required for spermatogenesis-specific 26G-RNAs and thermotolerant sperm in Caenorhabditis elegans. Proc Natl Acad Sci U S A (2010) 1.81
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A single Argonaute protein mediates both transcriptional and posttranscriptional silencing in Schizosaccharomyces pombe. Genes Dev (2004) 1.69
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The 3'-to-5' exoribonuclease Nibbler shapes the 3' ends of microRNAs bound to Drosophila Argonaute1. Curr Biol (2011) 1.66
A member of the polymerase beta nucleotidyltransferase superfamily is required for RNA interference in C. elegans. Curr Biol (2005) 1.61
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The C. elegans CSR-1 argonaute pathway counteracts epigenetic silencing to promote germline gene expression. Dev Cell (2013) 1.60
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A role for microRNAs in the Drosophila circadian clock. Genes Dev (2009) 1.56
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