Published in Cell on December 28, 2007
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The role of microRNA-221 and microRNA-222 in androgen-independent prostate cancer cell lines. Cancer Res (2009) 1.88
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MicroRNA-101 negatively regulates Ezh2 and its expression is modulated by androgen receptor and HIF-1alpha/HIF-1beta. Mol Cancer (2010) 1.87
miR-126 and miR-126* repress recruitment of mesenchymal stem cells and inflammatory monocytes to inhibit breast cancer metastasis. Nat Cell Biol (2013) 1.79
Targets of miR-200c mediate suppression of cell motility and anoikis resistance. Breast Cancer Res (2011) 1.74
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HuR protein attenuates miRNA-mediated repression by promoting miRISC dissociation from the target RNA. Nucleic Acids Res (2012) 1.58
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Repression of VEGFA by CA-rich element-binding microRNAs is modulated by hnRNP L. EMBO J (2011) 1.44
The complexity of miRNA-mediated repression. Cell Death Differ (2014) 1.44
MicroRNA-23a Curbs Necrosis during Early T Cell Activation by Enforcing Intracellular Reactive Oxygen Species Equilibrium. Immunity (2016) 1.41
microRNAs in the regulation of adipogenesis and obesity. Curr Mol Med (2011) 1.39
Global analyses of the effect of different cellular contexts on microRNA targeting. Mol Cell (2014) 1.38
Pumilio facilitates miRNA regulation of the E2F3 oncogene. Genes Dev (2012) 1.36
MicroRNAs distinguish translational from transcriptional silencing during endotoxin tolerance. J Biol Chem (2010) 1.36
Sequence context outside the target region influences the effectiveness of miR-223 target sites in the RhoB 3'UTR. Nucleic Acids Res (2009) 1.35
Site-specific crosslinking of human microRNPs to RNA targets. RNA (2008) 1.35
The code within the code: microRNAs target coding regions. Cell Cycle (2010) 1.35
Roquin binds inducible costimulator mRNA and effectors of mRNA decay to induce microRNA-independent post-transcriptional repression. Nat Immunol (2010) 1.33
Small RNAs in early mammalian development: from gametes to gastrulation. Development (2011) 1.33
Transgenerational genetic effects of the paternal Y chromosome on daughters' phenotypes. Epigenomics (2010) 1.31
DAZL relieves miRNA-mediated repression of germline mRNAs by controlling poly(A) tail length in zebrafish. PLoS One (2009) 1.29
Regulation of human chondrocyte function through direct inhibition of cartilage master regulator SOX9 by microRNA-145 (miRNA-145). J Biol Chem (2011) 1.29
MicroRNA transfection and AGO-bound CLIP-seq data sets reveal distinct determinants of miRNA action. RNA (2011) 1.26
microRNAs and RNA-binding proteins: a complex network of interactions and reciprocal regulations in cancer. RNA Biol (2013) 1.26
Computational methods to identify miRNA targets. Semin Cell Dev Biol (2010) 1.21
Selective inhibition of microRNA accessibility by RBM38 is required for p53 activity. Nat Commun (2011) 1.20
The RNA-binding protein HuR opposes the repression of ERBB-2 gene expression by microRNA miR-331-3p in prostate cancer cells. J Biol Chem (2011) 1.20
Regulation of cyclin-dependent kinase 4 translation through CUG-binding protein 1 and microRNA-222 by polyamines. Mol Biol Cell (2011) 1.19
MicroRNA involvement in the pathogenesis of neuroblastoma: potential for microRNA mediated therapeutics. Curr Pharm Des (2009) 1.18
Early zebrafish development: it's in the maternal genes. Curr Opin Genet Dev (2009) 1.15
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Characterisation and germline transmission of cultured avian primordial germ cells. PLoS One (2010) 1.14
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Affinity purification of microRNA-133a with the cardiac transcription factor, Hand2. Proc Natl Acad Sci U S A (2010) 1.14
Ribosomal protein L11 recruits miR-24/miRISC to repress c-Myc expression in response to ribosomal stress. Mol Cell Biol (2011) 1.13
Alternatively expressed domains of AU-rich element RNA-binding protein 1 (AUF1) regulate RNA-binding affinity, RNA-induced protein oligomerization, and the local conformation of bound RNA ligands. J Biol Chem (2010) 1.12
Targeting oncogenic miR-335 inhibits growth and invasion of malignant astrocytoma cells. Mol Cancer (2011) 1.11
Friend or foe: the role of microRNA in chemotherapy resistance. Acta Pharmacol Sin (2013) 1.11
MicroRNAs in Neural Stem Cells and Neurogenesis. Front Neurosci (2012) 1.10
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miR-195 competes with HuR to modulate stim1 mRNA stability and regulate cell migration. Nucleic Acids Res (2013) 1.09
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Regulation of male germ cell cycle arrest and differentiation by DND1 is modulated by genetic background. Development (2010) 1.08
Ancestral paternal genotype controls body weight and food intake for multiple generations. Hum Mol Genet (2010) 1.08
Widespread context dependency of microRNA-mediated regulation. Genome Res (2014) 1.08
BAX-mediated cell death affects early germ cell loss and incidence of testicular teratomas in Dnd1(Ter/Ter) mice. Dev Biol (2009) 1.08
Transcriptional analysis of pluripotency reveals the Hippo pathway as a barrier to reprogramming. Hum Mol Genet (2012) 1.07
Evolution of the human-specific microRNA miR-941. Nat Commun (2012) 1.06
MicroRNA-mediated mRNA translation activation in quiescent cells and oocytes involves recruitment of a nuclear microRNP. Sci Rep (2012) 1.06
Modulation of neoplastic gene regulatory pathways by the RNA-binding factor AUF1. Front Biosci (Landmark Ed) (2011) 1.06
Germline stem cells: origin and destiny. Cell Stem Cell (2012) 1.04
miR-181a regulates cap-dependent translation of p27(kip1) mRNA in myeloid cells. Mol Cell Biol (2009) 1.04
Design of small molecule-responsive microRNAs based on structural requirements for Drosha processing. Nucleic Acids Res (2010) 1.04
MicroRNA-24 targeting RNA-binding protein DND1 in tongue squamous cell carcinoma. FEBS Lett (2010) 1.03
The Grainyhead transcription factor Grhl3/Get1 suppresses miR-21 expression and tumorigenesis in skin: modulation of the miR-21 target MSH2 by RNA-binding protein DND1. Oncogene (2012) 1.03
MicroRNAs as Haematopoiesis Regulators. Adv Hematol (2013) 1.03
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Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy (2012) 20.08
Automated macromolecular model building for X-ray crystallography using ARP/wARP version 7. Nat Protoc (2008) 16.53
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A genetic screen implicates miRNA-372 and miRNA-373 as oncogenes in testicular germ cell tumors. Cell (2006) 11.01
A large-scale RNAi screen in human cells identifies new components of the p53 pathway. Nature (2004) 8.67
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The microRNAs miR-373 and miR-520c promote tumour invasion and metastasis. Nat Cell Biol (2008) 7.86
Programmed cell death 4 (PDCD4) is an important functional target of the microRNA miR-21 in breast cancer cells. J Biol Chem (2007) 7.46
MicroRNA-10a binds the 5'UTR of ribosomal protein mRNAs and enhances their translation. Mol Cell (2008) 6.58
ARP/wARP and automatic interpretation of protein electron density maps. Methods Enzymol (2003) 6.37
A role for Piwi and piRNAs in germ cell maintenance and transposon silencing in Zebrafish. Cell (2007) 6.31
Regulation of the p27(Kip1) tumor suppressor by miR-221 and miR-222 promotes cancer cell proliferation. EMBO J (2007) 6.26
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Control of chemokine-guided cell migration by ligand sequestration. Cell (2008) 4.61
miR-148 targets human DNMT3b protein coding region. RNA (2008) 4.56
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The PTEN-regulating microRNA miR-26a is amplified in high-grade glioma and facilitates gliomagenesis in vivo. Genes Dev (2009) 4.15
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Breaking good resolutions with ARP/wARP. J Synchrotron Radiat (2003) 3.87
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A new generation of crystallographic validation tools for the protein data bank. Structure (2011) 3.41
Migration of zebrafish primordial germ cells: a role for myosin contraction and cytoplasmic flow. Dev Cell (2006) 3.39
A genetic screen identifies PITX1 as a suppressor of RAS activity and tumorigenicity. Cell (2005) 3.35
Guidance of primordial germ cell migration by the chemokine SDF-1. Cell (2002) 3.22
Structure and E3-ligase activity of the Ring-Ring complex of polycomb proteins Bmi1 and Ring1b. EMBO J (2006) 3.21
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MicroRNA and cancer. Mol Oncol (2012) 3.10
Regulation of the adenomatous polyposis coli gene by the miR-135 family in colorectal cancer. Cancer Res (2008) 3.06
The developmental miRNA profiles of zebrafish as determined by small RNA cloning. Genes Dev (2005) 2.94
Stable X chromosome inactivation involves the PRC1 Polycomb complex and requires histone MACROH2A1 and the CULLIN3/SPOP ubiquitin E3 ligase. Proc Natl Acad Sci U S A (2005) 2.81
Survivin is required for a sustained spindle checkpoint arrest in response to lack of tension. EMBO J (2003) 2.70
miR-200b mediates post-transcriptional repression of ZFHX1B. RNA (2007) 2.67
A Pumilio-induced RNA structure switch in p27-3' UTR controls miR-221 and miR-222 accessibility. Nat Cell Biol (2010) 2.53
ARP/wARP and molecular replacement: the next generation. Acta Crystallogr D Biol Crystallogr (2007) 2.43
Alternative cleavage and polyadenylation: extent, regulation and function. Nat Rev Genet (2013) 2.37
The tumor-suppressive functions of the human INK4A locus. Cancer Cell (2003) 2.31
CXCR7 functions as a scavenger for CXCL12 and CXCL11. PLoS One (2010) 2.28
The protein that binds to DNA base J in trypanosomatids has features of a thymidine hydroxylase. Nucleic Acids Res (2007) 2.19
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The poly(A)-binding protein nuclear 1 suppresses alternative cleavage and polyadenylation sites. Cell (2012) 2.14
The chemokine SDF1/CXCL12 and its receptor CXCR4 regulate mouse germ cell migration and survival. Development (2003) 2.13
PDB_REDO: constructive validation, more than just looking for errors. Acta Crystallogr D Biol Crystallogr (2012) 2.08
AAA ATPase p97/valosin-containing protein interacts with gp78, a ubiquitin ligase for endoplasmic reticulum-associated degradation. J Biol Chem (2004) 2.07
MiRNA-27a controls FBW7/hCDC4-dependent cyclin E degradation and cell cycle progression. Cell Cycle (2011) 2.06
A role for Rho GTPases and cell-cell adhesion in single-cell motility in vivo. Nat Cell Biol (2009) 2.05
Polo-like kinase-1 controls proteasome-dependent degradation of Claspin during checkpoint recovery. Curr Biol (2006) 2.02
Ptprj is a candidate for the mouse colon-cancer susceptibility locus Scc1 and is frequently deleted in human cancers. Nat Genet (2002) 2.00
microRNA-101 is a potent inhibitor of autophagy. EMBO J (2011) 2.00
Deregulation of microRNA-503 contributes to diabetes mellitus-induced impairment of endothelial function and reparative angiogenesis after limb ischemia. Circulation (2011) 1.99
"Conditional Restraints": Restraining the Free Atoms in ARP/wARP. Structure (2009) 1.98
Homologous recombination and nonhomologous end-joining repair pathways regulate fragile site stability. Genes Dev (2005) 1.97
Marginating dendritic cells of the tumor microenvironment cross-present tumor antigens and stably engage tumor-specific T cells. Cancer Cell (2012) 1.95
A high-throughput splinkerette-PCR method for the isolation and sequencing of retroviral insertion sites. Nat Protoc (2009) 1.95
Inhibition of autotaxin by lysophosphatidic acid and sphingosine 1-phosphate. J Biol Chem (2005) 1.95
MiR-203 controls proliferation, migration and invasive potential of prostate cancer cell lines. Cell Cycle (2011) 1.89
Genomic loss of miR-486 regulates tumor progression and the OLFM4 antiapoptotic factor in gastric cancer. Clin Cancer Res (2011) 1.86
Structural basis of substrate discrimination and integrin binding by autotaxin. Nat Struct Mol Biol (2011) 1.81
BRD7 is a candidate tumour suppressor gene required for p53 function. Nat Cell Biol (2010) 1.76
Methylation-mediated silencing and tumour suppressive function of hsa-miR-124 in cervical cancer. Mol Cancer (2010) 1.69
Isolation of microRNA targets using biotinylated synthetic microRNAs. Methods (2007) 1.69
Crystal structure of the retinoblastoma tumor suppressor protein bound to E2F and the molecular basis of its regulation. Proc Natl Acad Sci U S A (2003) 1.68
MicroRNA-145 targets YES and STAT1 in colon cancer cells. PLoS One (2010) 1.64
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Structures of Escherichia coli DNA mismatch repair enzyme MutS in complex with different mismatches: a common recognition mode for diverse substrates. Nucleic Acids Res (2003) 1.62
Gene expression profiling reveals a signaling role of glutathione in redox regulation. Proc Natl Acad Sci U S A (2005) 1.57
MicroRNA regulation of autophagy. Carcinogenesis (2012) 1.56
Immunofluorescence-based screening identifies germ cell associated microRNA 302 as an antagonist to p63 expression. Cell Cycle (2009) 1.56
Mechanism of USP7/HAUSP activation by its C-terminal ubiquitin-like domain and allosteric regulation by GMP-synthetase. Mol Cell (2011) 1.56
The vertebrate mitotic checkpoint protein BUBR1 is an unusual pseudokinase. Dev Cell (2012) 1.55
A knowledge-driven approach for crystallographic protein model completion. Acta Crystallogr D Biol Crystallogr (2008) 1.53
Interplay between microRNAs and RNA-binding proteins determines developmental processes. Cell Cycle (2008) 1.51
HIV-1 Nef interferes with host cell motility by deregulation of Cofilin. Cell Host Microbe (2009) 1.50
Automatic rebuilding and optimization of crystallographic structures in the Protein Data Bank. Bioinformatics (2011) 1.48
The role and regulation of blebs in cell migration. Curr Opin Cell Biol (2013) 1.48
Development without germ cells: the role of the germ line in zebrafish sex differentiation. Proc Natl Acad Sci U S A (2005) 1.47
miR-449 inhibits cell proliferation and is down-regulated in gastric cancer. Mol Cancer (2011) 1.46