Published in Proc Natl Acad Sci U S A on January 22, 2008
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Calcium-dependent molecular spring elements in the giant protein titin. Proc Natl Acad Sci U S A (2003) 2.16
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The muscle ankyrin repeat proteins: CARP, ankrd2/Arpp and DARP as a family of titin filament-based stress response molecules. J Mol Biol (2003) 2.12
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Identification of a novel frameshift mutation in the giant muscle filament titin in a large Australian family with dilated cardiomyopathy. J Mol Med (Berl) (2006) 2.05
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PKC phosphorylation of titin's PEVK element: a novel and conserved pathway for modulating myocardial stiffness. Circ Res (2009) 1.91
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Nebulette mutations are associated with dilated cardiomyopathy and endocardial fibroelastosis. J Am Coll Cardiol (2010) 1.88
Structural basis of hepatocyte growth factor/scatter factor and MET signalling. Proc Natl Acad Sci U S A (2006) 1.85
Shortening of the elastic tandem immunoglobulin segment of titin leads to diastolic dysfunction. Circulation (2013) 1.83
Structural basis for autoinhibition of ESCRT-III CHMP3. J Mol Biol (2008) 1.78
X-ray scattering study of activated Arp2/3 complex with bound actin-WCA. Structure (2008) 1.75
Thin filament length dysregulation contributes to muscle weakness in nemaline myopathy patients with nebulin deficiency. Hum Mol Genet (2009) 1.73
The structure and binding behavior of the bacterial cell surface layer protein SbsC. Structure (2008) 1.72
Structural insights into the molecular organization of the S-layer from Clostridium difficile. Mol Microbiol (2009) 1.71
The PHD and chromo domains regulate the ATPase activity of the human chromatin remodeler CHD4. J Mol Biol (2012) 1.69
Crystal structure of the 80S yeast ribosome. Curr Opin Struct Biol (2012) 1.67
Structural basis of dcp2 recognition and activation by dcp1. Mol Cell (2008) 1.65
Dimerization of the cardiac ankyrin protein CARP: implications for MARP titin-based signaling. J Muscle Res Cell Motil (2005) 1.62
Molecular mechanics of cardiac titin's PEVK and N2B spring elements. J Biol Chem (2002) 1.61
A crescent-shaped ALIX dimer targets ESCRT-III CHMP4 filaments. Structure (2009) 1.61
Cooperative control of striated muscle mass and metabolism by MuRF1 and MuRF2. EMBO J (2007) 1.61
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Structural insights into eRF3 and stop codon recognition by eRF1. Genes Dev (2009) 1.57
Cardiac titin: an adjustable multi-functional spring. J Physiol (2002) 1.56
Structural analysis of intrinsically disordered proteins by small-angle X-ray scattering. Mol Biosyst (2011) 1.56
Structural bases for the interaction of frataxin with the central components of iron-sulphur cluster assembly. Nat Commun (2010) 1.56
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The SAXS solution structure of RF1 differs from its crystal structure and is similar to its ribosome bound cryo-EM structure. Mol Cell (2005) 1.53
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Genetic variation in titin in arrhythmogenic right ventricular cardiomyopathy-overlap syndromes. Circulation (2011) 1.51
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Hierarchical structure controls nanomechanical properties of vimentin intermediate filaments. PLoS One (2009) 1.49
C-terminal titin deletions cause a novel early-onset myopathy with fatal cardiomyopathy. Ann Neurol (2007) 1.47
Conditional expression of mutant M-line titins results in cardiomyopathy with altered sarcomere structure. J Biol Chem (2002) 1.47
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The structure of Lethocerus troponin C: insights into the mechanism of stretch activation in muscles. Structure (2007) 1.45
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Structure and RNA interactions of the N-terminal RRM domains of PTB. Structure (2004) 1.35
The structural basis of signal transduction for the response regulator PrrA from Mycobacterium tuberculosis. J Biol Chem (2006) 1.34
Association of the chaperone alphaB-crystallin with titin in heart muscle. J Biol Chem (2003) 1.31
Atomic structures of two novel immunoglobulin-like domain pairs in the actin cross-linking protein filamin. J Biol Chem (2009) 1.31
Conformation of polypyrimidine tract binding protein in solution. Structure (2006) 1.30
Stress-induced dilated cardiomyopathy in a knock-in mouse model mimicking human titin-based disease. J Mol Cell Cardiol (2009) 1.30
Structural insights into the dynamics and function of the C-terminus of the E. coli RNA chaperone Hfq. Nucleic Acids Res (2011) 1.30
Low-resolution structure of a vesicle disrupting α-synuclein oligomer that accumulates during fibrillation. Proc Natl Acad Sci U S A (2011) 1.29
Structure-function relations of the giant elastic protein titin in striated and smooth muscle cells. Muscle Nerve (2007) 1.29
Truncation of titin's elastic PEVK region leads to cardiomyopathy with diastolic dysfunction. Circ Res (2009) 1.29
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Molecular dissection of the interaction of desmin with the C-terminal region of nebulin. J Struct Biol (2002) 1.27
X-ray and neutron small-angle scattering analysis of the complex formed by the Met receptor and the Listeria monocytogenes invasion protein InlB. J Mol Biol (2008) 1.27
Structural characterization of protein-protein complexes by integrating computational docking with small-angle scattering data. J Mol Biol (2010) 1.26
The complete mouse nebulin gene sequence and the identification of cardiac nebulin. J Mol Biol (2003) 1.26
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Different molecular mechanics displayed by titin's constitutively and differentially expressed tandem Ig segments. J Struct Biol (2002) 1.22
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