Published in Biochemistry on January 24, 2008
Osh4p exchanges sterols for phosphatidylinositol 4-phosphate between lipid bilayers. J Cell Biol (2011) 2.22
Orientation and dynamics of transmembrane peptides: the power of simple models. Eur Biophys J (2009) 1.18
Cholesterol as a co-solvent and a ligand for membrane proteins. Protein Sci (2013) 0.97
Dynamic Heterogeneous Dielectric Generalized Born (DHDGB): An implicit membrane model with a dynamically varying bilayer thickness. J Chem Theory Comput (2013) 0.90
Membrane microheterogeneity: Förster resonance energy transfer characterization of lateral membrane domains. Eur Biophys J (2009) 0.83
Quantification of protein-lipid selectivity using FRET. Eur Biophys J (2010) 0.78
Influence of High pH and Cholesterol on Single Arginine-Containing Transmembrane Peptide Helices. Biochemistry (2016) 0.78
Peptide-membrane interactions of arginine-tryptophan peptides probed using quartz crystal microbalance with dissipation monitoring. Eur Biophys J (2014) 0.75
Two dimensional then layer chromatographic separation of polar lipids and determination of phospholipids by phosphorus analysis of spots. Lipids (1970) 11.81
Fluorescence energy transfer as a spectroscopic ruler. Annu Rev Biochem (1978) 11.41
Cation-pi interactions in chemistry and biology: a new view of benzene, Phe, Tyr, and Trp. Science (1996) 8.34
The description of membrane lipid conformation, order and dynamics by 2H-NMR. Biochim Biophys Acta (1983) 5.96
The preference of tryptophan for membrane interfaces. Biochemistry (1998) 5.10
Lipid rafts: contentious only from simplistic standpoints. Nat Rev Mol Cell Biol (2006) 4.94
Lateral diffusion in the liquid phases of dimyristoylphosphatidylcholine/cholesterol lipid bilayers: a free volume analysis. Biochemistry (1992) 4.57
Rotamer libraries in the 21st century. Curr Opin Struct Biol (2002) 4.09
An analytic solution to the Förster energy transfer problem in two dimensions. Biophys J (1979) 4.03
How proteins adapt to a membrane-water interface. Trends Biochem Sci (2000) 3.76
Membrane lateral compressibility determined by NMR and x-ray diffraction: effect of acyl chain polyunsaturation. Biophys J (1997) 3.47
Lipid rafts: heterogeneity on the high seas. Biochem J (2004) 3.46
Cholesterol interactions with phospholipids in membranes. Prog Lipid Res (2002) 3.34
Hydrophobic interactions of peptides with membrane interfaces. Biochim Biophys Acta (1998) 2.79
Role of cholesterol in lipid raft formation: lessons from lipid model systems. Biochim Biophys Acta (2003) 2.67
The functions of tryptophan residues in membrane proteins. Protein Eng (1992) 2.45
Different membrane anchoring positions of tryptophan and lysine in synthetic transmembrane alpha-helical peptides. J Biol Chem (1999) 2.44
Phosphatidylcholine acyl unsaturation modulates the decrease in interfacial elasticity induced by cholesterol. Biophys J (1997) 2.16
Relationships between lipid membrane area, hydrophobic thickness, and acyl-chain orientational order. The effects of cholesterol. Biophys J (1990) 2.15
Geometry and intrinsic tilt of a tryptophan-anchored transmembrane alpha-helix determined by (2)H NMR. Biophys J (2002) 2.01
Roles of bilayer material properties in function and distribution of membrane proteins. Annu Rev Biophys Biomol Struct (2006) 1.99
Tilt angles of transmembrane model peptides in oriented and non-oriented lipid bilayers as determined by 2H solid-state NMR. Biophys J (2004) 1.98
Interfacial anchor properties of tryptophan residues in transmembrane peptides can dominate over hydrophobic matching effects in peptide-lipid interactions. Biochemistry (2003) 1.92
Cholesterol and the interaction of proteins with membrane domains. Prog Lipid Res (2006) 1.64
Peptides in lipid bilayers: the power of simple models. Curr Opin Struct Biol (2006) 1.55
Orientations of the tryptophan 9 and 11 side chains of the gramicidin channel based on deuterium nuclear magnetic resonance spectroscopy. Biophys J (1994) 1.52
The aromatic residues Trp and Phe have different effects on the positioning of a transmembrane helix in the microsomal membrane. Biochemistry (1999) 1.49
Transverse location of the fluorescent probe 1,6-diphenyl-1,3,5-hexatriene in model lipid bilayer membrane systems by resonance excitation energy transfer. Biochemistry (1985) 1.43
Synthetic peptides as models for intrinsic membrane proteins. FEBS Lett (2003) 1.39
Orientation of the valine-1 side chain of the gramicidin transmembrane channel and implications for channel functioning. A 2H NMR study. Biochemistry (1992) 1.38
The potential of fluorescent and spin-labeled steroid analogs to mimic natural cholesterol. J Biol Chem (2003) 1.37
Tuning a bacterial chemoreceptor with protein-membrane interactions. Biochemistry (2006) 1.37
Design and characterization of gramicidin channels. Methods Enzymol (1999) 1.35
Tryptophan residues flanking the second transmembrane helix (TM2) set the signaling state of the Tar chemoreceptor. Biochemistry (2005) 1.32
Resonance energy transfer in a model system of membranes: application to gel and liquid crystalline phases. Biophys J (1996) 1.31
Cholesterol orientation and dynamics in dimyristoylphosphatidylcholine bilayers: a solid state deuterium NMR analysis. Biophys J (1999) 1.30
Interactions of cholesterol with the membrane lipid matrix. A solid state NMR approach. Biochimie (1991) 1.29
Orientation and motion of tryptophan interfacial anchors in membrane-spanning peptides. Biochemistry (2007) 1.20
Analysis of the role of interfacial tryptophan residues in controlling the topology of membrane proteins. Biochemistry (2000) 1.18
Interaction of phosphatidylserine synthase from E. coli with lipid bilayers: coupled plasmon-waveguide resonance spectroscopy studies. Biophys J (2000) 1.14
Interfacial positioning and stability of transmembrane peptides in lipid bilayers studied by combining hydrogen/deuterium exchange and mass spectrometry. J Biol Chem (2001) 1.09
Cyclodextrin-catalyzed extraction of fluorescent sterols from monolayer membranes and small unilamellar vesicles. Chem Phys Lipids (2000) 1.07
delta 5,7,9(11)-Cholestatrien-3 beta-ol: a fluorescent cholesterol analogue. Chem Phys Lipids (1984) 1.04
Probing the effects of membrane cholesterol in the Torpedo californica acetylcholine receptor and the novel lipid-exposed mutation alpha C418W in Xenopus oocytes. J Biol Chem (2001) 1.03
Analysis of side-chain rotamers in transmembrane proteins. Biophys J (2004) 1.00
Mutation of tryptophan residues in lipoprotein lipase. Effects on stability, immunoreactivity, and catalytic properties. J Biol Chem (1997) 0.98
Differential scanning calorimetry and (2)H nuclear magnetic resonance and Fourier transform infrared spectroscopy studies of the effects of transmembrane alpha-helical peptides on the organization of phosphatidylcholine bilayers. Biochim Biophys Acta (2001) 0.97
Influence of cholesterol on gramicidin-induced HII phase formation in phosphatidylcholine model membranes. Biochim Biophys Acta (1988) 0.97
Interaction of melittin with membrane cholesterol: a fluorescence approach. Biophys J (2004) 0.96
Membrane-bound conformation of M13 major coat protein: a structure validation through FRET-derived constraints. J Biol Chem (2005) 0.94
Combined experimental/theoretical refinement of indole ring geometry using deuterium magnetic resonance and ab initio calculations. J Am Chem Soc (2003) 0.93
A synergistic effect between cholesterol and tryptophan-flanked transmembrane helices modulates membrane curvature. Biochemistry (2005) 0.93
Inhibition of lipid raft-dependent signaling by a dystrophy-associated mutant of caveolin-3. J Biol Chem (2002) 0.91
Structure and dynamics of the gammaM4 transmembrane domain of the acetylcholine receptor in lipid bilayers: insights into receptor assembly and function. Mol Membr Biol (2006) 0.90
Physical properties of the fluorescent sterol probe dehydroergosterol. Biochim Biophys Acta (1986) 0.90
Cholesterol modulates the organization of the gammaM4 transmembrane domain of the muscle nicotinic acetylcholine receptor. Biophys J (2004) 0.88
Molecular organization in striated domains induced by transmembrane alpha-helical peptides in dipalmitoyl phosphatidylcholine bilayers. Biochemistry (2005) 0.84
Sphingomyelin/phosphatidylcholine/cholesterol phase diagram: boundaries and composition of lipid rafts. Biophys J (2003) 4.48
Bilayer thickness and membrane protein function: an energetic perspective. Annu Rev Biophys Biomol Struct (2007) 3.52
Bilayer-dependent inhibition of mechanosensitive channels by neuroactive peptide enantiomers. Nature (2004) 3.12
Protein-lipid interactions studied with designed transmembrane peptides: role of hydrophobic matching and interfacial anchoring. Mol Membr Biol (2003) 2.28
Membrane damage by human islet amyloid polypeptide through fibril growth at the membrane. Proc Natl Acad Sci U S A (2008) 2.25
Lipid rafts have different sizes depending on membrane composition: a time-resolved fluorescence resonance energy transfer study. J Mol Biol (2005) 2.17
Geometry and intrinsic tilt of a tryptophan-anchored transmembrane alpha-helix determined by (2)H NMR. Biophys J (2002) 2.01
Tilt angles of transmembrane model peptides in oriented and non-oriented lipid bilayers as determined by 2H solid-state NMR. Biophys J (2004) 1.98
Nonbilayer lipids affect peripheral and integral membrane proteins via changes in the lateral pressure profile. Biochim Biophys Acta (2004) 1.94
Interfacial anchor properties of tryptophan residues in transmembrane peptides can dominate over hydrophobic matching effects in peptide-lipid interactions. Biochemistry (2003) 1.92
Regulation of sodium channel function by bilayer elasticity: the importance of hydrophobic coupling. Effects of Micelle-forming amphiphiles and cholesterol. J Gen Physiol (2004) 1.83
Capsaicin regulates voltage-dependent sodium channels by altering lipid bilayer elasticity. Mol Pharmacol (2005) 1.70
Lateral diffusion of membrane proteins. J Am Chem Soc (2009) 1.65
Islet amyloid polypeptide-induced membrane leakage involves uptake of lipids by forming amyloid fibers. FEBS Lett (2004) 1.59
Snorkeling of lysine side chains in transmembrane helices: how easy can it get? FEBS Lett (2003) 1.57
A critical role for ceramide synthase 2 in liver homeostasis: I. alterations in lipid metabolic pathways. J Biol Chem (2010) 1.56
Peptides in lipid bilayers: the power of simple models. Curr Opin Struct Biol (2006) 1.55
Genistein can modulate channel function by a phosphorylation-independent mechanism: importance of hydrophobic mismatch and bilayer mechanics. Biochemistry (2003) 1.55
Lipid dependence of membrane anchoring properties and snorkeling behavior of aromatic and charged residues in transmembrane peptides. Biochemistry (2002) 1.54
On the orientation of a designed transmembrane peptide: toward the right tilt angle? J Am Chem Soc (2007) 1.54
An electrostatic/hydrogen bond switch as the basis for the specific interaction of phosphatidic acid with proteins. J Biol Chem (2007) 1.50
How protein transmembrane segments sense the lipid environment. Biochemistry (2007) 1.50
Lipid packing drives the segregation of transmembrane helices into disordered lipid domains in model membranes. Proc Natl Acad Sci U S A (2011) 1.50
Docosahexaenoic acid alters bilayer elastic properties. Proc Natl Acad Sci U S A (2007) 1.48
Influence of flanking residues on tilt and rotation angles of transmembrane peptides in lipid bilayers. A solid-state 2H NMR study. Biochemistry (2005) 1.45
Changes in transmembrane helix alignment by arginine residues revealed by solid-state NMR experiments and coarse-grained MD simulations. J Am Chem Soc (2010) 1.41
Sphingomyelin is much more effective than saturated phosphatidylcholine in excluding unsaturated phosphatidylcholine from domains formed with cholesterol. FEBS Lett (2003) 1.37
Self-association of transmembrane alpha-helices in model membranes: importance of helix orientation and role of hydrophobic mismatch. J Biol Chem (2005) 1.36
Islet amyloid polypeptide inserts into phospholipid monolayers as monomer. J Mol Biol (2005) 1.35
Curcumin is a modulator of bilayer material properties. Biochemistry (2007) 1.34
Quantifying molecular partition into model systems of biomembranes: an emphasis on optical spectroscopic methods. Biochim Biophys Acta (2003) 1.32
Nanocapsules: lipid-coated aggregates of cisplatin with high cytotoxicity. Nat Med (2002) 1.32
Ceramide-domain formation and collapse in lipid rafts: membrane reorganization by an apoptotic lipid. Biophys J (2006) 1.32
Transbilayer movement of phospholipids in biogenic membranes. Biochemistry (2004) 1.32
Role of helix 0 of the N-BAR domain in membrane curvature generation. Biophys J (2008) 1.31
Phase diagrams of lipid mixtures relevant to the study of membrane rafts. Biochim Biophys Acta (2008) 1.29
Phospholipid flop induced by transmembrane peptides in model membranes is modulated by lipid composition. Biochemistry (2003) 1.28
Hydrophobic mismatch between helices and lipid bilayers. Biophys J (2003) 1.28
Amphiphile regulation of ion channel function by changes in the bilayer spring constant. Proc Natl Acad Sci U S A (2010) 1.26
Comparison of "Polarization inversion with spin exchange at magic angle" and "geometric analysis of labeled alanines" methods for transmembrane helix alignment. J Am Chem Soc (2008) 1.24
Synthesis of DOTA-conjugated multivalent cyclic-RGD peptide dendrimers via 1,3-dipolar cycloaddition and their biological evaluation: implications for tumor targeting and tumor imaging purposes. Org Biomol Chem (2007) 1.24
Ceramide-platform formation and -induced biophysical changes in a fluid phospholipid membrane. Mol Membr Biol (2006) 1.23
The effects of hydrophobic mismatch between phosphatidylcholine bilayers and transmembrane alpha-helical peptides depend on the nature of interfacially exposed aromatic and charged residues. Biochemistry (2002) 1.22
Nonequilibrium phenomena in the phase separation of a two-component lipid bilayer. Biophys J (2002) 1.22
Hydrophobic coupling of lipid bilayer energetics to channel function. J Gen Physiol (2003) 1.20
Charged or aromatic anchor residue dependence of transmembrane peptide tilt. J Biol Chem (2010) 1.20
Orientation and motion of tryptophan interfacial anchors in membrane-spanning peptides. Biochemistry (2007) 1.20
Orientation and dynamics of transmembrane peptides: the power of simple models. Eur Biophys J (2009) 1.18
Membrane lipid domains and rafts: current applications of fluorescence lifetime spectroscopy and imaging. Chem Phys Lipids (2008) 1.18
Formation of ceramide/sphingomyelin gel domains in the presence of an unsaturated phospholipid: a quantitative multiprobe approach. Biophys J (2007) 1.16
Recent insights in islet amyloid polypeptide-induced membrane disruption and its role in beta-cell death in type 2 diabetes mellitus. Exp Diabetes Res (2008) 1.15
Complexity of lipid domains and rafts in giant unilamellar vesicles revealed by combining imaging and microscopic and macroscopic time-resolved fluorescence. Biophys J (2007) 1.15
Influence of lipids on membrane assembly and stability of the potassium channel KcsA. FEBS Lett (2002) 1.15
The preference of tryptophan for membrane interfaces: insights from N-methylation of tryptophans in gramicidin channels. J Biol Chem (2008) 1.14
Dependence of M13 major coat protein oligomerization and lateral segregation on bilayer composition. Biophys J (2003) 1.14
Stability of KcsA tetramer depends on membrane lateral pressure. Biochemistry (2004) 1.12
Gramicidin channels. IEEE Trans Nanobioscience (2005) 1.12
Mechanism and kinetics of peptide partitioning into membranes from all-atom simulations of thermostable peptides. J Am Chem Soc (2010) 1.09
Domain formation and stability in complex lipid bilayers as reported by cholestatrienol. Biophys J (2005) 1.08
Photocrosslinking and click chemistry enable the specific detection of proteins interacting with phospholipids at the membrane interface. Chem Biol (2009) 1.08
Membrane domain formation, interdigitation, and morphological alterations induced by the very long chain asymmetric C24:1 ceramide. Biophys J (2008) 1.07
Membrane interaction of the glycosyltransferase MurG: a special role for cardiolipin. J Bacteriol (2003) 1.06
Cholesterol-rich fluid membranes solubilize ceramide domains: implications for the structure and dynamics of mammalian intracellular and plasma membranes. J Biol Chem (2009) 1.06
Importance of hydrophobic matching for spontaneous insertion of a single-spanning membrane protein. Biochemistry (2002) 1.05
Tilt and rotation angles of a transmembrane model peptide as studied by fluorescence spectroscopy. Biophys J (2009) 1.05
Factors affecting gas-phase deuterium scrambling in peptide ions and their implications for protein structure determination. J Am Chem Soc (2002) 1.05
Lipid raft composition modulates sphingomyelinase activity and ceramide-induced membrane physical alterations. Biophys J (2009) 1.04
Bacterial reaction centers purified with styrene maleic acid copolymer retain native membrane functional properties and display enhanced stability. Angew Chem Int Ed Engl (2014) 1.04
Cholesterol and ergosterol influence nystatin surface aggregation: relation to pore formation. Biophys J (2004) 1.03
Cholesterol interactions with fluid-phase phospholipids: effect on the lateral organization of the bilayer. Biophys J (2008) 1.03
Cooperative partition model of nystatin interaction with phospholipid vesicles. Biophys J (2003) 1.02
Order parameters of a transmembrane helix in a fluid bilayer: case study of a WALP peptide. Biophys J (2010) 1.02
Domain formation in phosphatidylcholine bilayers containing transmembrane peptides: specific effects of flanking residues. Biochemistry (2002) 1.01
Synthesis and applications of biomedical and pharmaceutical polymers via click chemistry methodologies. Bioconjug Chem (2009) 1.01
Sphingomyelin and sphingomyelin synthase (SMS) in the malignant transformation of glioma cells and in 2-hydroxyoleic acid therapy. Proc Natl Acad Sci U S A (2011) 1.01