Published in EMBO J on February 21, 2008
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Desmoglein 1-dependent suppression of EGFR signaling promotes epidermal differentiation and morphogenesis. J Cell Biol (2009) 1.73
Suppression of the epithelial-mesenchymal transition by Grainyhead-like-2. Cancer Res (2012) 1.50
Epidermal wound repair is regulated by the planar cell polarity signaling pathway. Dev Cell (2010) 1.25
Grainyhead-like 2 regulates epithelial morphogenesis by establishing functional tight junctions through the organization of a molecular network among claudin3, claudin4, and Rab25. Mol Biol Cell (2012) 1.15
The transcription factors Grainyhead-like 2 and NK2-homeobox 1 form a regulatory loop that coordinates lung epithelial cell morphogenesis and differentiation. J Biol Chem (2012) 1.10
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Grainyhead-like 2 enhances the human telomerase reverse transcriptase gene expression by inhibiting DNA methylation at the 5'-CpG island in normal human keratinocytes. J Biol Chem (2010) 1.04
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Recent discoveries concerning the involvement of transcription factors from the Grainyhead-like family in cancer. Exp Biol Med (Maywood) (2015) 0.88
A Tourist-like MITE insertion in the upstream region of the BnFLC.A10 gene is associated with vernalization requirement in rapeseed (Brassica napus L.). BMC Plant Biol (2012) 0.88
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An epidermal barrier wound repair pathway in Drosophila is mediated by grainy head. Science (2005) 2.20
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Inositol- and folate-resistant neural tube defects in mice lacking the epithelial-specific factor Grhl-3. Nat Med (2003) 1.51
Regulation of post-embryonic neuroblasts by Drosophila Grainyhead. Mech Dev (2005) 1.47
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Desmoglein isoform distribution affects stratum corneum structure and function. J Cell Biol (2001) 1.21
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The identification and characterization of human Sister-of-Mammalian Grainyhead (SOM) expands the grainyhead-like family of developmental transcription factors. Biochem J (2003) 1.10
The grainy head transcription factor is essential for the function of the frizzled pathway in the Drosophila wing. Mech Dev (2004) 1.07
Delineation of diversified desmoglein distribution in stratified squamous epithelia: implications in diseases. Exp Dermatol (2006) 1.06
The expression of desmoglein isoforms in cultured human keratinocytes is regulated by calcium, serum, and protein kinase C. Exp Cell Res (1998) 1.06
Striate palmoplantar keratoderma arising from desmoplakin and desmoglein 1 mutations is associated with contrasting perturbations of desmosomes and the keratin filament network. Br J Dermatol (2004) 1.05
Spectrum of dominant mutations in the desmosomal cadherin desmoglein 1, causing the skin disease striate palmoplantar keratoderma. Eur J Hum Genet (2001) 1.03
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Expression of desmoglein 1 compensates for genetic loss of desmoglein 3 in keratinocyte adhesion. J Invest Dermatol (2002) 1.01
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Epidermal impermeable barriers in mouse and fly. Curr Opin Genet Dev (2005) 0.99
Inherited disorders of desmosomes. Australas J Dermatol (2005) 0.96
Desmogleins 1 and 3 in the companion layer anchor mouse anagen hair to the follicle. J Invest Dermatol (2004) 0.93
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A novel mouse desmosomal cadherin family member, desmoglein 1 gamma. Exp Dermatol (2003) 0.83
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Novel member of the mouse desmoglein gene family: Dsg1-beta. Exp Dermatol (2003) 0.81
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Programmed anuclear cell death delimits platelet life span. Cell (2007) 5.98
The transcription factor Erg is essential for definitive hematopoiesis and the function of adult hematopoietic stem cells. Nat Immunol (2008) 3.07
A network of PDZ-containing proteins regulates T cell polarity and morphology during migration and immunological synapse formation. Immunity (2005) 2.97
A homolog of Drosophila grainy head is essential for epidermal integrity in mice. Science (2005) 2.72
The Lmo2 oncogene initiates leukemia in mice by inducing thymocyte self-renewal. Science (2010) 2.64
CUX1 is a haploinsufficient tumor suppressor gene on chromosome 7 frequently inactivated in acute myeloid leukemia. Blood (2012) 2.51
Genetically tagging endothelial cells in vivo: bone marrow-derived cells do not contribute to tumor endothelium. Blood (2004) 2.30
Subsequent primary malignancies in patients with nonmelanoma skin cancer in England: a national record-linkage study. Cancer Epidemiol Biomarkers Prev (2014) 2.26
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The critical regulator of embryonic hematopoiesis, SCL, is vital in the adult for megakaryopoiesis, erythropoiesis, and lineage choice in CFU-S12. Proc Natl Acad Sci U S A (2003) 2.12
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Targeting of the tumor suppressor GRHL3 by a miR-21-dependent proto-oncogenic network results in PTEN loss and tumorigenesis. Cancer Cell (2011) 1.63
RNAi screen identifies Jarid1b as a major regulator of mouse HSC activity. Blood (2013) 1.62
Comparative analysis of paracrine factor expression in human adult mesenchymal stem cells derived from bone marrow, adipose, and dermal tissue. Stem Cells Dev (2012) 1.61
Androgenetic alopecia: pathogenesis and potential for therapy. Expert Rev Mol Med (2002) 1.59
Mcl-1 and Bcl-x(L) coordinately regulate megakaryocyte survival. Blood (2012) 1.57
An RNAi screen identifies Msi2 and Prox1 as having opposite roles in the regulation of hematopoietic stem cell activity. Cell Stem Cell (2010) 1.52
Inositol- and folate-resistant neural tube defects in mice lacking the epithelial-specific factor Grhl-3. Nat Med (2003) 1.51
Summary of North American Hair Research Society (NAHRS)-sponsored Workshop on Cicatricial Alopecia, Duke University Medical Center, February 10 and 11, 2001. J Am Acad Dermatol (2003) 1.42
A mouse model of harlequin ichthyosis delineates a key role for Abca12 in lipid homeostasis. PLoS Genet (2008) 1.40
Biopsy-proven acute interstitial nephritis associated with the tyrosine kinase inhibitor sunitinib: a class effect? Nephrol Dial Transplant (2008) 1.39
Spatial and temporal expression of the Grainyhead-like transcription factor family during murine development. Gene Expr Patterns (2006) 1.35
Rejection of syngeneic colon carcinoma by CTLs expressing single-chain antibody receptors codelivering CD28 costimulation. J Immunol (2002) 1.31
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Identification of a PRMT5-dependent repressor complex linked to silencing of human fetal globin gene expression. Blood (2010) 1.28
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Inflammation and primary demyelination induced by the intraspinal injection of lipopolysaccharide. Brain (2005) 1.26
Epidermal wound repair is regulated by the planar cell polarity signaling pathway. Dev Cell (2010) 1.25
Regional neural tube closure defined by the Grainy head-like transcription factors. Dev Biol (2010) 1.23
Drugs and hair loss. Dermatol Clin (2012) 1.22
The mitochondrial genome of Acropora tenuis (Cnidaria; Scleractinia) contains a large group I intron and a candidate control region. J Mol Evol (2002) 1.22
A role for pericytes as microenvironmental regulators of human skin tissue regeneration. J Clin Invest (2009) 1.22
SCL is required for normal function of short-term repopulating hematopoietic stem cells. Blood (2004) 1.20
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Distinct domains of erythroid Krüppel-like factor modulate chromatin remodeling and transactivation at the endogenous beta-globin gene promoter. Mol Cell Biol (2002) 1.17
The unique and cooperative roles of the Grainy head-like transcription factors in epidermal development reflect unexpected target gene specificity. Dev Biol (2010) 1.17
Hypotrichosis and nail dysplasia: a novel hidrotic ectodermal dysplasia. Australas J Dermatol (2004) 1.12
Ligand binding determines whether CD46 is internalized by clathrin-coated pits or macropinocytosis. J Biol Chem (2003) 1.10
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The identification and characterization of human Sister-of-Mammalian Grainyhead (SOM) expands the grainyhead-like family of developmental transcription factors. Biochem J (2003) 1.10
Thrombocytopenia and kidney disease in mice with a mutation in the C1galt1 gene. Proc Natl Acad Sci U S A (2006) 1.09
The functional basis for hemophagocytic lymphohistiocytosis in a patient with co-inherited missense mutations in the perforin (PFN1) gene. J Exp Med (2004) 1.05
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A functional role for CD28 costimulation in tumor recognition by single-chain receptor-modified T cells. Cancer Gene Ther (2004) 1.03
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Female pattern hair loss: current treatment concepts. Clin Interv Aging (2007) 1.02
Functional but abnormal adult erythropoiesis in the absence of the stem cell leukemia gene. Mol Cell Biol (2005) 1.02
Components of both major axial patterning systems of the Bilateria are differentially expressed along the primary axis of a 'radiate' animal, the anthozoan cnidarian Acropora millepora. Dev Biol (2006) 1.02
Aberrant mast-cell differentiation in mice lacking the stem-cell leukemia gene. Blood (2007) 1.01
Granzyme M mediates a novel form of perforin-dependent cell death. J Biol Chem (2004) 1.01
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The role of p22 NF-E4 in human globin gene switching. J Biol Chem (2004) 0.99
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