Published in Blood on May 21, 2010
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Human SWI/SNF-associated PRMT5 methylates histone H3 arginine 8 and negatively regulates expression of ST7 and NM23 tumor suppressor genes. Mol Cell Biol (2004) 3.90
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Methyl-CpG binding protein MBD1 couples histone H3 methylation at lysine 9 by SETDB1 to DNA replication and chromatin assembly. Mol Cell (2004) 3.60
PRMT5-mediated methylation of histone H4R3 recruits DNMT3A, coupling histone and DNA methylation in gene silencing. Nat Struct Mol Biol (2009) 3.46
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mSin3A/histone deacetylase 2- and PRMT5-containing Brg1 complex is involved in transcriptional repression of the Myc target gene cad. Mol Cell Biol (2003) 2.72
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An evaluation, comparison, and accurate benchmarking of several publicly available MS/MS search algorithms: sensitivity and specificity analysis. Proteomics (2005) 3.51
A high-confidence human plasma proteome reference set with estimated concentrations in PeptideAtlas. Mol Cell Proteomics (2011) 3.37
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A family with erythrocytosis establishes a role for prolyl hydroxylase domain protein 2 in oxygen homeostasis. Proc Natl Acad Sci U S A (2006) 2.90
iProphet: multi-level integrative analysis of shotgun proteomic data improves peptide and protein identification rates and error estimates. Mol Cell Proteomics (2011) 2.88
A homolog of Drosophila grainy head is essential for epidermal integrity in mice. Science (2005) 2.72
The Lmo2 oncogene initiates leukemia in mice by inducing thymocyte self-renewal. Science (2010) 2.64
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Comparison of ultracentrifugation, density gradient separation, and immunoaffinity capture methods for isolating human colon cancer cell line LIM1863-derived exosomes. Methods (2012) 2.46
HtrA2 promotes cell death through its serine protease activity and its ability to antagonize inhibitor of apoptosis proteins. J Biol Chem (2001) 2.33
Genetically tagging endothelial cells in vivo: bone marrow-derived cells do not contribute to tumor endothelium. Blood (2004) 2.30
Mining a tandem mass spectrometry database to determine the trends and global factors influencing peptide fragmentation. Anal Chem (2003) 2.28
The critical regulator of embryonic hematopoiesis, SCL, is vital in the adult for megakaryopoiesis, erythropoiesis, and lineage choice in CFU-S12. Proc Natl Acad Sci U S A (2003) 2.12
Proteomics analysis of A33 immunoaffinity-purified exosomes released from the human colon tumor cell line LIM1215 reveals a tissue-specific protein signature. Mol Cell Proteomics (2009) 2.08
Reproducible quantification of cancer-associated proteins in body fluids using targeted proteomics. Sci Transl Med (2012) 2.06
Comparative proteomics evaluation of plasma exosome isolation techniques and assessment of the stability of exosomes in normal human blood plasma. Proteomics (2013) 1.93
An aspartyl protease directs malaria effector proteins to the host cell. Nature (2010) 1.92
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Role of the Plasmodium export element in trafficking parasite proteins to the infected erythrocyte. Traffic (2008) 1.64
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The Mtb proteome library: a resource of assays to quantify the complete proteome of Mycobacterium tuberculosis. Cell Host Microbe (2013) 1.44
Two distinct populations of exosomes are released from LIM1863 colon carcinoma cell-derived organoids. Mol Cell Proteomics (2012) 1.44
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Plasmin activates the lymphangiogenic growth factors VEGF-C and VEGF-D. J Exp Med (2003) 1.35
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Rejection of syngeneic colon carcinoma by CTLs expressing single-chain antibody receptors codelivering CD28 costimulation. J Immunol (2002) 1.31
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SOCS-6 binds to insulin receptor substrate 4, and mice lacking the SOCS-6 gene exhibit mild growth retardation. Mol Cell Biol (2002) 1.28
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Epidermal wound repair is regulated by the planar cell polarity signaling pathway. Dev Cell (2010) 1.25
Regional neural tube closure defined by the Grainy head-like transcription factors. Dev Biol (2010) 1.23
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SCL is required for normal function of short-term repopulating hematopoietic stem cells. Blood (2004) 1.20
Total and putative surface proteomics of malaria parasite salivary gland sporozoites. Mol Cell Proteomics (2013) 1.19
IOP1, a novel hydrogenase-like protein that modulates hypoxia-inducible factor-1alpha activity. Biochem J (2007) 1.17
Enzymic, phylogenetic, and structural characterization of the unusual papain-like protease domain of Plasmodium falciparum SERA5. J Biol Chem (2003) 1.17
Distinct domains of erythroid Krüppel-like factor modulate chromatin remodeling and transactivation at the endogenous beta-globin gene promoter. Mol Cell Biol (2002) 1.17
Identification of protein complexes in detergent-resistant membranes of Plasmodium falciparum schizonts. Mol Biochem Parasitol (2007) 1.17
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Characterization of an antagonist interleukin-6 dimer by stable isotope labeling, cross-linking, and mass spectrometry. J Biol Chem (2002) 1.14
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New and improved proteomics technologies for understanding complex biological systems: addressing a grand challenge in the life sciences. Proteomics (2012) 1.14
Proteomics-driven cancer biomarker discovery: looking to the future. Curr Opin Chem Biol (2008) 1.13
SRM targeted proteomics in search for biomarkers of HCV-induced progression of fibrosis to cirrhosis in HALT-C patients. Proteomics (2012) 1.11
Adoptive transfer of gene-engineered CD4+ helper T cells induces potent primary and secondary tumor rejection. Blood (2005) 1.10
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Comprehensive lipidome profiling of isogenic primary and metastatic colon adenocarcinoma cell lines. Anal Chem (2012) 1.08
First report of Toxoplasma gondii infection in market-sold adult chickens, ducks and pigeons in northwest China. Parasit Vectors (2012) 1.07
Human microglial cells synthesize albumin in brain. PLoS One (2008) 1.07
Transgenic barley (Hordeum vulgare L.) expressing the wheat aluminium resistance gene (TaALMT1) shows enhanced phosphorus nutrition and grain production when grown on an acid soil. Plant Biotechnol J (2009) 1.06
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Ankyrin repeat and suppressors of cytokine signaling box protein asb-9 targets creatine kinase B for degradation. J Biol Chem (2006) 1.05
The functional basis for hemophagocytic lymphohistiocytosis in a patient with co-inherited missense mutations in the perforin (PFN1) gene. J Exp Med (2004) 1.05
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Oncogenic H-ras reprograms Madin-Darby canine kidney (MDCK) cell-derived exosomal proteins following epithelial-mesenchymal transition. Mol Cell Proteomics (2013) 1.04
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