Published in Dev Biol on July 21, 2010
Neural tube defects. Annu Rev Neurosci (2014) 1.69
Recurrent somatic mutations in POLR2A define a distinct subset of meningiomas. Nat Genet (2016) 1.63
Suppression of the epithelial-mesenchymal transition by Grainyhead-like-2. Cancer Res (2012) 1.50
Grainyhead-like 2 regulates neural tube closure and adhesion molecule expression during neural fold fusion. Dev Biol (2011) 1.45
Interferon regulatory factor 6 promotes differentiation of the periderm by activating expression of Grainyhead-like 3. J Invest Dermatol (2012) 1.09
Dual roles of the transcription factor grainyhead-like 2 (GRHL2) in breast cancer. J Biol Chem (2013) 1.07
Mechanisms of tissue fusion during development. Development (2012) 0.99
How to form and close the brain: insight into the mechanism of cranial neural tube closure in mammals. Cell Mol Life Sci (2012) 0.92
Genome-scale study of transcription factor expression in the branching mouse lung. Dev Dyn (2012) 0.91
Gene expression profiling at early organogenesis reveals both common and diverse mechanisms in foregut patterning. Dev Biol (2011) 0.91
Mutations in GRHL2 result in an autosomal-recessive ectodermal Dysplasia syndrome. Am J Hum Genet (2014) 0.90
A Grainyhead-Like 2/Ovo-Like 2 Pathway Regulates Renal Epithelial Barrier Function and Lumen Expansion. J Am Soc Nephrol (2015) 0.90
Recent discoveries concerning the involvement of transcription factors from the Grainyhead-like family in cancer. Exp Biol Med (Maywood) (2015) 0.88
Fate Specification of Neural Plate Border by Canonical Wnt Signaling and Grhl3 is Crucial for Neural Tube Closure. EBioMedicine (2015) 0.86
Over-expression of Grhl2 causes spina bifida in the Axial defects mutant mouse. Hum Mol Genet (2011) 0.86
Epithelial fusion during neural tube morphogenesis. Birth Defects Res A Clin Mol Teratol (2012) 0.86
GRHL2 coordinates regeneration of a polarized mucociliary epithelium from basal stem cells. J Cell Biol (2015) 0.84
Confirmation of GRHL2 as the gene for the DFNA28 locus. Am J Med Genet A (2013) 0.83
Distinct Expression Patterns Of Causative Genes Responsible For Hereditary Progressive Hearing Loss In Non-Human Primate Cochlea. Sci Rep (2016) 0.78
Grainyhead-like 2 downstream targets act to suppress epithelial-to-mesenchymal transition during neural tube closure. Development (2016) 0.78
Grainyhead-like 2 inhibits the coactivator p300, suppressing tubulogenesis and the epithelial-mesenchymal transition. Mol Biol Cell (2016) 0.76
Neural tube closure: cellular, molecular and biomechanical mechanisms. Development (2017) 0.76
Neural tube defects: from a proteomic standpoint. Metabolites (2015) 0.75
Genetic Variation in POU4F3 and GRHL2 Associated with Noise-Induced Hearing Loss in Chinese Population: A Case-Control Study. Int J Environ Res Public Health (2016) 0.75
Stable Binding of the Conserved Transcription Factor Grainy Head to Its Target Genes Throughout Drosophila melanogaster Development. Genetics (2016) 0.75
The ubiquitin ligase LIN41/TRIM71 targets p53 to antagonize cell death and differentiation pathways during stem cell differentiation. Cell Death Differ (2017) 0.75
Mice lacking the conserved transcription factor Grainyhead-like 3 (Grhl3) display increased apposition of the frontal and parietal bones during embryonic development. BMC Dev Biol (2016) 0.75
Grhl2 is required in nonneural tissues for neural progenitor survival and forebrain development. Genesis (2015) 0.75
Claudins are essential for cell shape changes and convergent extension movements during neural tube closure. Dev Biol (2017) 0.75
Genome-wide identification of Grainy head targets in Drosophila reveals regulatory interactions with the POU-domain transcription factor, Vvl. Development (2017) 0.75
Adenovirus-associated virus vector-mediated gene transfer in hemophilia B. N Engl J Med (2011) 11.01
A homolog of Drosophila grainy head is essential for epidermal integrity in mice. Science (2005) 2.72
The Lmo2 oncogene initiates leukemia in mice by inducing thymocyte self-renewal. Science (2010) 2.64
CUX1 is a haploinsufficient tumor suppressor gene on chromosome 7 frequently inactivated in acute myeloid leukemia. Blood (2012) 2.51
Genetically tagging endothelial cells in vivo: bone marrow-derived cells do not contribute to tumor endothelium. Blood (2004) 2.30
The critical regulator of embryonic hematopoiesis, SCL, is vital in the adult for megakaryopoiesis, erythropoiesis, and lineage choice in CFU-S12. Proc Natl Acad Sci U S A (2003) 2.12
A functional screen to identify novel effectors of hematopoietic stem cell activity. Cell (2009) 1.86
Single-chain antigen recognition receptors that costimulate potent rejection of established experimental tumors. Blood (2002) 1.83
The deacetylase SIRT1 promotes membrane localization and activation of Akt and PDK1 during tumorigenesis and cardiac hypertrophy. Sci Signal (2011) 1.69
The sirtuin SIRT6 blocks IGF-Akt signaling and development of cardiac hypertrophy by targeting c-Jun. Nat Med (2012) 1.69
A highly conserved novel family of mammalian developmental transcription factors related to Drosophila grainyhead. Mech Dev (2002) 1.64
Targeting of the tumor suppressor GRHL3 by a miR-21-dependent proto-oncogenic network results in PTEN loss and tumorigenesis. Cancer Cell (2011) 1.63
RNAi screen identifies Jarid1b as a major regulator of mouse HSC activity. Blood (2013) 1.62
An RNAi screen identifies Msi2 and Prox1 as having opposite roles in the regulation of hematopoietic stem cell activity. Cell Stem Cell (2010) 1.52
Inositol- and folate-resistant neural tube defects in mice lacking the epithelial-specific factor Grhl-3. Nat Med (2003) 1.51
Perturbed desmosomal cadherin expression in grainy head-like 1-null mice. EMBO J (2008) 1.42
[Medical students' attitudes towards tobacco smoking at the first and sixth year of their studies 2002-2008]. Pneumonol Alergol Pol (2009) 1.42
Spatial and temporal expression of the Grainyhead-like transcription factor family during murine development. Gene Expr Patterns (2006) 1.35
Rejection of syngeneic colon carcinoma by CTLs expressing single-chain antibody receptors codelivering CD28 costimulation. J Immunol (2002) 1.31
Identification of a PRMT5-dependent repressor complex linked to silencing of human fetal globin gene expression. Blood (2010) 1.28
Epidermal wound repair is regulated by the planar cell polarity signaling pathway. Dev Cell (2010) 1.25
The mitochondrial genome of Acropora tenuis (Cnidaria; Scleractinia) contains a large group I intron and a candidate control region. J Mol Evol (2002) 1.22
SCL is required for normal function of short-term repopulating hematopoietic stem cells. Blood (2004) 1.20
Distinct domains of erythroid Krüppel-like factor modulate chromatin remodeling and transactivation at the endogenous beta-globin gene promoter. Mol Cell Biol (2002) 1.17
The unique and cooperative roles of the Grainy head-like transcription factors in epidermal development reflect unexpected target gene specificity. Dev Biol (2010) 1.17
Adoptive transfer of gene-engineered CD4+ helper T cells induces potent primary and secondary tumor rejection. Blood (2005) 1.10
The identification and characterization of human Sister-of-Mammalian Grainyhead (SOM) expands the grainyhead-like family of developmental transcription factors. Biochem J (2003) 1.10
The functional basis for hemophagocytic lymphohistiocytosis in a patient with co-inherited missense mutations in the perforin (PFN1) gene. J Exp Med (2004) 1.05
Coral development: from classical embryology to molecular control. Int J Dev Biol (2002) 1.05
Novel roles for erythroid Ankyrin-1 revealed through an ENU-induced null mouse mutant. Blood (2009) 1.04
A functional role for CD28 costimulation in tumor recognition by single-chain receptor-modified T cells. Cancer Gene Ther (2004) 1.03
BMP4-dependent expression of Xenopus Grainyhead-like 1 is essential for epidermal differentiation. Development (2005) 1.02
Functional but abnormal adult erythropoiesis in the absence of the stem cell leukemia gene. Mol Cell Biol (2005) 1.02
Components of both major axial patterning systems of the Bilateria are differentially expressed along the primary axis of a 'radiate' animal, the anthozoan cnidarian Acropora millepora. Dev Biol (2006) 1.02
Aberrant mast-cell differentiation in mice lacking the stem-cell leukemia gene. Blood (2007) 1.01
Bridging cancer biology with the clinic: relative expression of a GRHL2-mediated gene-set pair predicts breast cancer metastasis. PLoS One (2013) 1.00
The role of p22 NF-E4 in human globin gene switching. J Biol Chem (2004) 0.99
Site-specific acetylation of the fetal globin activator NF-E4 prevents its ubiquitination and regulates its interaction with the histone deacetylase, HDAC1. J Biol Chem (2004) 0.99
Epidermal impermeable barriers in mouse and fly. Curr Opin Genet Dev (2005) 0.99
Binding of the RING polycomb proteins to specific target genes in complex with the grainyhead-like family of developmental transcription factors. Mol Cell Biol (2002) 0.98
Functional interaction of CP2 with GATA-1 in the regulation of erythroid promoters. Mol Cell Biol (2006) 0.97
The Hedgehog receptor Patched1 regulates myeloid and lymphoid progenitors by distinct cell-extrinsic mechanisms. Blood (2009) 0.95
Disruption of growth factor receptor-binding protein 10 in the pancreas enhances β-cell proliferation and protects mice from streptozotocin-induced β-cell apoptosis. Diabetes (2012) 0.95
p19Arf represses platelet-derived growth factor receptor β by transcriptional and posttranscriptional mechanisms. Mol Cell Biol (2012) 0.95
A critical role for the transcription factor Scl in platelet production during stress thrombopoiesis. Blood (2006) 0.94
Expression of the Arf tumor suppressor gene is controlled by Tgfbeta2 during development. Development (2009) 0.94
Defective extraembryonic angiogenesis in mice lacking LBP-1a, a member of the grainyhead family of transcription factors. Mol Cell Biol (2004) 0.92
Inhibition of apoptosis by BCL2 prevents leukemic transformation of a murine myelodysplastic syndrome. Blood (2012) 0.90
Tgfbeta signaling directly induces Arf promoter remodeling by a mechanism involving Smads 2/3 and p38 MAPK. J Biol Chem (2010) 0.89
Grhl3 and Lmo4 play coordinate roles in epidermal migration. Dev Biol (2008) 0.89
Brain parenchymal damage after haematopoietic stem cell transplantation for severe sickle cell disease. Br J Haematol (2005) 0.88
ENU mutagenesis identifies the first mouse mutants reproducing human β-thalassemia at the genomic level. Blood Cells Mol Dis (2012) 0.88