Published in PLoS One on March 19, 2008
Interactions of AChE with Aβ Aggregates in Alzheimer's Brain: Therapeutic Relevance of IDN 5706. Front Mol Neurosci (2011) 0.86
Protein misfolding and aggregation in Alzheimer's disease and type 2 diabetes mellitus. CNS Neurol Disord Drug Targets (2014) 0.79
Insights into Kinetics of Agitation-Induced Aggregation of Hen Lysozyme under Heat and Acidic Conditions from Various Spectroscopic Methods. PLoS One (2015) 0.76
Melanosomal formation of PMEL core amyloid is driven by aromatic residues. Sci Rep (2017) 0.75
Conformational preferences of a 14-residue fibrillogenic peptide from acetylcholinesterase. Biochemistry (2010) 0.75
SWISS-MODEL and the Swiss-PdbViewer: an environment for comparative protein modeling. Electrophoresis (1997) 57.27
Soluble protein oligomers in neurodegeneration: lessons from the Alzheimer's amyloid beta-peptide. Nat Rev Mol Cell Biol (2007) 17.69
Atomic structures of amyloid cross-beta spines reveal varied steric zippers. Nature (2007) 10.02
A structural model for Alzheimer's beta -amyloid fibrils based on experimental constraints from solid state NMR. Proc Natl Acad Sci U S A (2002) 9.55
Thioflavine T interaction with synthetic Alzheimer's disease beta-amyloid peptides: detection of amyloid aggregation in solution. Protein Sci (1993) 7.92
Models of amyloid seeding in Alzheimer's disease and scrapie: mechanistic truths and physiological consequences of the time-dependent solubility of amyloid proteins. Annu Rev Biochem (1997) 7.62
The Cationminus signpi Interaction. Chem Rev (1997) 7.56
Experimental constraints on quaternary structure in Alzheimer's beta-amyloid fibrils. Biochemistry (2006) 6.54
The 'Arctic' APP mutation (E693G) causes Alzheimer's disease by enhanced Abeta protofibril formation. Nat Neurosci (2001) 5.29
Protein aggregation and aggregate toxicity: new insights into protein folding, misfolding diseases and biological evolution. J Mol Med (Berl) (2003) 5.15
Rationalization of the effects of mutations on peptide and protein aggregation rates. Nature (2003) 4.98
Amyloid fibrillogenesis: themes and variations. Curr Opin Struct Biol (2000) 4.76
Spontaneous assembly of a self-complementary oligopeptide to form a stable macroscopic membrane. Proc Natl Acad Sci U S A (1993) 4.05
Amyloid fibrils from muscle myoglobin. Nature (2001) 3.93
pi-Stacking interactions. Alive and well in proteins. J Biol Chem (1998) 3.92
Conformational constraints for amyloid fibrillation: the importance of being unfolded. Biochim Biophys Acta (2004) 3.69
Amyloid fibril formation by an SH3 domain. Proc Natl Acad Sci U S A (1998) 3.55
Review: history of the amyloid fibril. J Struct Biol (2000) 3.49
A possible role for pi-stacking in the self-assembly of amyloid fibrils. FASEB J (2002) 3.34
Quantitative evaluation of congo red binding to amyloid-like proteins with a beta-pleated sheet conformation. J Histochem Cytochem (1989) 3.26
Dissecting the assembly of Abeta16-22 amyloid peptides into antiparallel beta sheets. Structure (2003) 3.18
Molecular basis for amyloid fibril formation and stability. Proc Natl Acad Sci U S A (2005) 3.00
Arrest of beta-amyloid fibril formation by a pentapeptide ligand. J Biol Chem (1996) 2.93
Alpha-synuclein, especially the Parkinson's disease-associated mutants, forms pore-like annular and tubular protofibrils. J Mol Biol (2002) 2.92
Dramatic aggregation of Alzheimer abeta by Cu(II) is induced by conditions representing physiological acidosis. J Biol Chem (1998) 2.78
Sequence determinants of amyloid fibril formation. Proc Natl Acad Sci U S A (2003) 2.71
Analysis of the minimal amyloid-forming fragment of the islet amyloid polypeptide. An experimental support for the key role of the phenylalanine residue in amyloid formation. J Biol Chem (2001) 2.42
De novo amyloid proteins from designed combinatorial libraries. Proc Natl Acad Sci U S A (1999) 2.38
Identification of a penta- and hexapeptide of islet amyloid polypeptide (IAPP) with amyloidogenic and cytotoxic properties. J Mol Biol (2000) 2.34
Elucidation of primary structure elements controlling early amyloid beta-protein oligomerization. J Biol Chem (2003) 2.31
Chemistry for the analysis of protein-protein interactions: rapid and efficient cross-linking triggered by long wavelength light. Proc Natl Acad Sci U S A (1999) 2.19
Aromatic interactions in model systems. Curr Opin Chem Biol (2002) 2.01
Guidelines for protein design: the energetics of beta sheet side chain interactions. Science (1995) 1.88
Surfactant properties of Alzheimer's A beta peptides and the mechanism of amyloid aggregation. J Biol Chem (1994) 1.88
An analysis of side chain interactions and pair correlations within antiparallel beta-sheets: the differences between backbone hydrogen-bonded and non-hydrogen-bonded residue pairs. Proteins (1995) 1.87
Cation-pi interactions in protein-protein interfaces. Proteins (2005) 1.83
The toxicity of the Alzheimer's beta-amyloid peptide correlates with a distinct fiber morphology. J Struct Biol (1997) 1.78
Aspects on human amyloid forms and their fibril polypeptides. FEBS J (2005) 1.71
Amyloid fibril formation by pentapeptide and tetrapeptide fragments of human calcitonin. J Biol Chem (2002) 1.66
Charge attraction and beta propensity are necessary for amyloid fibril formation from tetrapeptides. J Biol Chem (2002) 1.63
On the role of surface tension in the stabilization of globular proteins. Protein Sci (1996) 1.50
Metal binding modes of Alzheimer's amyloid beta-peptide in insoluble aggregates and soluble complexes. Biochemistry (2000) 1.42
Non-hydrogen bond interactions involving the methionine sulfur atom. J Biomol Struct Dyn (2001) 1.41
The octapeptide repeats in mammalian prion protein constitute a pH-dependent folding and aggregation site. J Mol Biol (2003) 1.40
Detecting hidden sequence propensity for amyloid fibril formation. Protein Sci (2004) 1.25
Structural diversity of amyloid fibril formed in human calcitonin as revealed by site-directed 13C solid-state NMR spectroscopy. Magn Reson Chem (2004) 1.21
Charge states rather than propensity for beta-structure determine enhanced fibrillogenesis in wild-type Alzheimer's beta-amyloid peptide compared to E22Q Dutch mutant. Protein Sci (2002) 1.19
Histidine-13 is a crucial residue in the zinc ion-induced aggregation of the A beta peptide of Alzheimer's disease. Biochemistry (1999) 1.16
Environment of tryptophan side chains in proteins. Proteins (2000) 1.15
Probing the initial stage of aggregation of the Abeta(10-35)-protein: assessing the propensity for peptide dimerization. J Mol Biol (2004) 1.12
Senile plaque composition and posttranslational modification of amyloid-beta peptide and associated proteins. Peptides (2002) 1.10
Preferential Cu2+ coordination by His96 and His111 induces beta-sheet formation in the unstructured amyloidogenic region of the prion protein. J Biol Chem (2004) 1.09
Butyrylcholinesterase attenuates amyloid fibril formation in vitro. Proc Natl Acad Sci U S A (2006) 1.08
Assessing the role of aromatic residues in the amyloid aggregation of human muscle acylphosphatase. Protein Sci (2006) 1.07
Examining the zinc binding site of the amyloid-beta peptide. Eur J Biochem (2000) 1.04
Sequence dependence of amyloid fibril formation: insights from molecular dynamics simulations. J Mol Biol (2005) 1.04
Conformational and geometrical properties of beta-sheets in proteins. I. Parallel beta-sheets. J Mol Biol (1981) 1.01
Structure and texture of fibrous crystals formed by Alzheimer's abeta(11-25) peptide fragment. Structure (2003) 0.99
Molecular isoform distribution and glycosylation of acetylcholinesterase are altered in brain and cerebrospinal fluid of patients with Alzheimer's disease. J Neurochem (1999) 0.99
Rapid method for measurement of surface tension in multiwell plates. Lab Invest (2004) 0.98
Memory deficits correlating with acetylcholinesterase splice shift and amyloid burden in doubly transgenic mice. Curr Alzheimer Res (2005) 0.96
Amyloid fibril formation by a synthetic peptide from a region of human acetylcholinesterase that is homologous to the Alzheimer's amyloid-beta peptide. Biochemistry (2002) 0.95
Protein stabilization by engineered metal chelation. Biotechnology (N Y) (1991) 0.93
The role of Phe in the formation of well-ordered oligomers of amyloidogenic hexapeptide (NFGAIL) observed in molecular dynamics simulations with explicit solvent. Biophys J (2005) 0.92
Controlling polymerization of beta-amyloid and prion-derived peptides with synthetic small molecule ligands. J Biol Chem (2000) 0.91
Heterologous amyloid seeding: revisiting the role of acetylcholinesterase in Alzheimer's disease. PLoS One (2007) 0.87
The organization of aromatic side groups in an amyloid fibril probed by solid-state 2H and 19F NMR spectroscopy. J Am Chem Soc (2006) 0.87
The intact human acetylcholinesterase C-terminal oligomerization domain is alpha-helical in situ and in isolation, but a shorter fragment forms beta-sheet-rich amyloid fibrils and protofibrillar oligomers. Biochemistry (2003) 0.83
NMR studies of model peptides of PHGGGWGQ repeats within the N-terminus of prion proteins: a loop conformation with histidine and tryptophan in close proximity. J Biochem (2000) 0.82
Interactions between cytochrome c2 and the photosynthetic reaction center from Rhodobacter sphaeroides: the cation-pi interaction. Biochemistry (2005) 0.81
Side chain interactions determine the amyloid organization: a single layer beta-sheet molecular structure of the calcitonin peptide segment 15-19. Phys Biol (2004) 0.79
Antigenic and genetic characteristics of swine-origin 2009 A(H1N1) influenza viruses circulating in humans. Science (2009) 25.61
Clinical aspects of pandemic 2009 influenza A (H1N1) virus infection. N Engl J Med (2010) 9.90
Surveillance of resistance to adamantanes among influenza A(H3N2) and A(H1N1) viruses isolated worldwide. J Infect Dis (2007) 5.21
Screening for Barrett's esophagus in colonoscopy patients with and without heartburn. Gastroenterology (2003) 2.59
Design of treatment trials for functional gastrointestinal disorders. Gastroenterology (2006) 2.58
Isolation and characterization of avian influenza viruses, including highly pathogenic H5N1, from poultry in live bird markets in Hanoi, Vietnam, in 2001. J Virol (2005) 2.51
Outbreak of variant influenza A(H3N2) virus in the United States. Clin Infect Dis (2013) 2.38
Localisation of DivIVA by targeting to negatively curved membranes. EMBO J (2009) 2.35
Hedgehog signaling regulates nociceptive sensitization. Curr Biol (2011) 1.81
The nuclear envelope can control gene expression and cell cycle progression via miRNA regulation. Cell Cycle (2010) 1.61
Nod1/RICK and TLR signaling regulate chemokine and antimicrobial innate immune responses in mesothelial cells. J Immunol (2007) 1.60
Clinical effectiveness of laparoscopic fundoplication in a U.S. community. Am J Med (2003) 1.57
Lamin B1 controls oxidative stress responses via Oct-1. J Cell Biol (2009) 1.56
Defects in lamin B1 expression or processing affect interphase chromosome position and gene expression. J Cell Biol (2007) 1.53
Homogeneous monocytes and macrophages from human embryonic stem cells following coculture-free differentiation in M-CSF and IL-3. Exp Hematol (2008) 1.52
The nucleoplasmic reticulum: form and function. Trends Cell Biol (2011) 1.48
Repetitive disruptions of the nuclear envelope invoke temporary loss of cellular compartmentalization in laminopathies. Hum Mol Genet (2011) 1.47
A critical role for phospholipase Cgamma2 in alphaIIbbeta3-mediated platelet spreading. J Biol Chem (2003) 1.36
Sorting of Fas ligand to secretory lysosomes is regulated by mono-ubiquitylation and phosphorylation. J Cell Sci (2006) 1.32
R292K substitution and drug susceptibility of influenza A(H7N9) viruses. Emerg Infect Dis (2013) 1.25
Phosphorylated BRCA1 is predominantly located in the nucleus and mitochondria. Mol Biol Cell (2004) 1.09
A novel role for BRCA1 in regulating breast cancer cell spreading and motility. J Cell Biol (2011) 1.08
A carboxyl-terminal interaction of lamin B1 is dependent on the CAAX endoprotease Rce1 and carboxymethylation. J Cell Biol (2003) 1.08
Combined zebrafish-yeast chemical-genetic screens reveal gene-copper-nutrition interactions that modulate melanocyte pigmentation. Dis Model Mech (2010) 1.04
Differences in influenza seasonality by latitude, northern India. Emerg Infect Dis (2014) 1.02
Genomic events underlying the changes in adamantane resistance among influenza A(H3N2) viruses during 2006-2008. Influenza Other Respir Viruses (2009) 0.99
Assessing mechanisms of GPIHBP1 and lipoprotein lipase movement across endothelial cells. J Lipid Res (2012) 0.98
Genetic analysis of avian influenza A viruses isolated from domestic waterfowl in live-bird markets of Hanoi, Vietnam, preceding fatal H5N1 human infections in 2004. Arch Virol (2009) 0.97
Sequential recruitment and combinatorial assembling of multiprotein complexes in transcriptional activation. Phys Rev Lett (2006) 0.96
A vitellogenic-like carboxypeptidase expressed by human macrophages is localized in endoplasmic reticulum and membrane ruffles. Int J Exp Pathol (2006) 0.94
Competing discrete interfacial effects are critical for amyloidogenesis. FASEB J (2009) 0.93
Analysis of influenza viruses from patients clinically suspected of infection with an oseltamivir resistant virus during the 2009 pandemic in the United States. Antiviral Res (2012) 0.93
The presence of valine at residue 129 in human prion protein accelerates amyloid formation. FEBS Lett (2005) 0.91
Isolation and characterization of TgVP1, a type I vacuolar H+-translocating pyrophosphatase from Toxoplasma gondii. The dynamics of its subcellular localization and the cellular effects of a diphosphonate inhibitor. J Biol Chem (2002) 0.91
The induction of a nucleoplasmic reticulum by prelamin A accumulation requires CTP:phosphocholine cytidylyltransferase-α. J Cell Sci (2012) 0.91
Link-space formalism for network analysis. Phys Rev E Stat Nonlin Soft Matter Phys (2008) 0.90
Lamin b1 polymorphism influences morphology of the nuclear envelope, cell cycle progression, and risk of neural tube defects in mice. PLoS Genet (2012) 0.90
HIV protease inhibitors inhibit FACE1/ZMPSTE24: a mechanism for acquired lipodystrophy in patients on highly active antiretroviral therapy? Biochem Soc Trans (2010) 0.89
The cellular location of self-antigen determines the positive and negative selection of autoreactive B cells. J Exp Med (2003) 0.89
Both exogenous commensal and endogenous self antigens stimulate T cell proliferation under lymphopenic conditions. Cell Immunol (2011) 0.87
Heterologous amyloid seeding: revisiting the role of acetylcholinesterase in Alzheimer's disease. PLoS One (2007) 0.87
The rule of bigeminy revisited: analysis in sudden cardiac death syndrome. J Electrocardiol (2006) 0.86
Polarization effects on contrast in structured illumination microscopy. Opt Lett (2012) 0.86
Prevalence of hyperprolactinaemia in a naturalistic cohort of schizophrenia and bipolar outpatients during treatment with typical and atypical antipsychotics. J Psychopharmacol (2007) 0.85
Influence of particle size and reactive oxygen species on cobalt chrome nanoparticle-mediated genotoxicity. Biomaterials (2013) 0.85
Combined effects of agitation, macromolecular crowding, and interfaces on amyloidogenesis. J Biol Chem (2012) 0.85
Elongation dynamics of amyloid fibrils: a rugged energy landscape picture. Phys Rev E Stat Nonlin Soft Matter Phys (2009) 0.84
Transcriptional and cellular responses to defective mitochondrial proteolysis in fission yeast. J Mol Biol (2011) 0.84
Mutations in congenital myasthenic syndromes reveal an epsilon subunit C-terminal cysteine, C470, crucial for maturation and surface expression of adult AChR. Hum Mol Genet (2002) 0.84
Identifying patients with gastroesophageal reflux disease: validation of a practical screening tool. Dig Dis Sci (2002) 0.83
Arbitrary self-assembly of peptide extracellular microscopic matrices. Angew Chem Int Ed Engl (2011) 0.82
A review of the association between antipsychotic use and hyperprolactinaemia. J Psychopharmacol (2008) 0.82
Enrichment of amyloidogenesis at an air-water interface. Biophys J (2012) 0.82
Prevalence of Barrett's Esophagus. Gastroenterology (2006) 0.81
Preparing for the availability of a partially effective HIV vaccine: some lessons from other licensed vaccines. Vaccine (2011) 0.80
Rapidly detecting disorder in rhythmic biological signals: a spectral entropy measure to identify cardiac arrhythmias. Phys Rev E Stat Nonlin Soft Matter Phys (2009) 0.80
The nuclear envelope and its involvement in cellular stress responses. Biochem Soc Trans (2011) 0.80
Self-selection and use patterns of over-the-counter omeprazole for frequent heartburn. Clin Gastroenterol Hepatol (2004) 0.80
Targeting cardiovascular protection: the concept of dual renin-angiotensin system control. Medscape J Med (2008) 0.80
Transcription factor sequestration by nuclear envelope components. Cell Cycle (2009) 0.79
No HOPE without proof: do ARBs meet the standard for cardiovascular protection? Medscape J Med (2008) 0.79
Prospects for renovascular protection by more aggressive renin-angiotensin system control. Medscape J Med (2008) 0.78
Is LMNB1 a susceptibility gene for neural tube defects in humans? Birth Defects Res A Clin Mol Teratol (2013) 0.78
The air-water interface determines the outcome of seeding during amyloidogenesis. Biochem J (2013) 0.78
Bioanalysis of N-acetyl-aspartyl-glutamate as a marker of glutamate carboxypeptidase II inhibition. Anal Biochem (2010) 0.77
Combined biochemical and cytological analysis of membrane trafficking using lectins. Anal Biochem (2013) 0.77
Designing non-native iron-binding site on a protein cage for biological synthesis of nanoparticles. Small (2014) 0.76
Nuclear envelope invaginations and cancer. Adv Exp Med Biol (2014) 0.76
Cardiac and vascular protection: the potential of ONTARGET. Medscape J Med (2008) 0.75
Treating to protect: current cardiovascular treatment approaches and remaining needs. Medscape J Med (2008) 0.75
Cardiovascular high-risk patients--treat to protect, but whom? Medscape J Med (2008) 0.75
"Register and Roll": A Novel Initiative to Improve First Door-to-Balloon Time in ST Elevation Myocardial Infarction. Cardiol Res Pract (2012) 0.75
Determination of Predominance of Influenza Virus Strains in the Americas. Emerg Infect Dis (2015) 0.75
Preparation of kinase-biased compounds in the search for lead inhibitors of kinase targets. Med Res Rev (2005) 0.75
2009 H1N1 swine flu: the 2010 perspective. Ann N Y Acad Sci (2010) 0.75
Heavyweight science. Vet Rec (2012) 0.75
A new dawn in cardio and vascular protection v. cardiovascular high-risk patients: treat to protect. Medscape J Med (2008) 0.75
Activation rather than Foxp3 expression determines that TGF-β-induced regulatory T cells out-compete naïve T cells in dendritic cell clustering. Eur J Immunol (2012) 0.75
Anti-biotin antibodies offer superior organelle-specific labelling of mitochondria over avidin or streptavidin. Methods Mol Biol (2008) 0.75
Ischemic Gastritis: A Multicenter Case Series of a Rare Clinical Entity and a Review of the Literature. J Clin Gastroenterol (2016) 0.75