Published in Brain Res Bull on November 20, 2007
A novel transgenic zebrafish model for blood-brain and blood-retinal barrier development. BMC Dev Biol (2010) 1.44
A zebrafish model of tauopathy allows in vivo imaging of neuronal cell death and drug evaluation. J Clin Invest (2009) 1.32
Zebrafish as tools for drug discovery. Nat Rev Drug Discov (2015) 1.28
Real-time observation of listeria monocytogenes-phagocyte interactions in living zebrafish larvae. Infect Immun (2009) 1.24
Establishment of a neuroepithelial barrier by Claudin5a is essential for zebrafish brain ventricular lumen expansion. Proc Natl Acad Sci U S A (2010) 1.17
Real-time whole-body visualization of Chikungunya Virus infection and host interferon response in zebrafish. PLoS Pathog (2013) 1.06
Functional characterisation of the maturation of the blood-brain barrier in larval zebrafish. PLoS One (2013) 1.04
Notch3 establishes brain vascular integrity by regulating pericyte number. Development (2013) 1.02
Exosome delivered anticancer drugs across the blood-brain barrier for brain cancer therapy in Danio rerio. Pharm Res (2015) 0.99
Brain barriers: Crosstalk between complex tight junctions and adherens junctions. J Cell Biol (2015) 0.91
Seizures induced by pentylenetetrazole in the adult zebrafish: a detailed behavioral characterization. PLoS One (2013) 0.89
Neurohypophyseal hormones manipulation modulate social and anxiety-related behavior in zebrafish. Psychopharmacology (Berl) (2011) 0.88
Discovering novel neuroactive drugs through high-throughput behavior-based chemical screening in the zebrafish. Front Pharmacol (2014) 0.86
Claudins in teleost fishes. Tissue Barriers (2013) 0.85
Regulation of zebrafish sleep and arousal states: current and prospective approaches. Front Neural Circuits (2013) 0.84
Zebrafish model of the blood-brain barrier: morphological and permeability studies. Methods Mol Biol (2011) 0.83
Effects of 6-hydroxydopamine exposure on motor activity and biochemical expression in zebrafish (Danio rerio) larvae. Zebrafish (2014) 0.83
In vivo analysis of hyaloid vasculature morphogenesis in zebrafish: A role for the lens in maturation and maintenance of the hyaloid. Dev Biol (2014) 0.82
Advancements in zebrafish applications for 21st century toxicology. Pharmacol Ther (2016) 0.82
From omics to drug metabolism and high content screen of natural product in zebrafish: a new model for discovery of neuroactive compound. Evid Based Complement Alternat Med (2012) 0.81
Modeling tuberculous meningitis in zebrafish using Mycobacterium marinum. Dis Model Mech (2014) 0.81
Can zebrafish be used as animal model to study Alzheimer's disease? Am J Neurodegener Dis (2012) 0.80
In vivo assessment of the permeability of the blood-brain barrier and blood-retinal barrier to fluorescent indoline derivatives in zebrafish. BMC Neurosci (2012) 0.80
Oncogenic KRAS promotes malignant brain tumors in zebrafish. Mol Cancer (2015) 0.80
Identification of a novel indoline derivative for in vivo fluorescent imaging of blood-brain barrier disruption in animal models. ACS Chem Neurosci (2013) 0.79
Detection of tight junction barrier function in vivo by biotin. Methods Mol Biol (2011) 0.79
Molecular determinants of blood-brain barrier permeation. Ther Deliv (2015) 0.78
Using visual lateralization to model learning and memory in zebrafish larvae. Sci Rep (2015) 0.77
Neural crest derivatives in ocular development: discerning the eye of the storm. Birth Defects Res C Embryo Today (2015) 0.77
Zebrafish as a model to investigate CNS myelination. Glia (2014) 0.77
A zebrafish model of hyperammonemia. Mol Genet Metab (2014) 0.77
Modelling inborn errors of metabolism in zebrafish. J Inherit Metab Dis (2014) 0.77
Infection of zebrafish embryos with live fluorescent Streptococcus pneumoniae as a real-time pneumococcal meningitis model. J Neuroinflammation (2016) 0.77
Choroid plexus in developmental and evolutionary perspective. Front Neurosci (2014) 0.76
Zebrafish models of Tauopathy. Biochim Biophys Acta (2010) 0.76
Leveraging Large-scale Behavioral Profiling in Zebrafish to Explore Neuroactive Polypharmacology. ACS Chem Biol (2016) 0.76
F-spondin/spon1b expression patterns in developing and adult zebrafish. PLoS One (2012) 0.76
Frog Virus 3 dissemination in the brain of tadpoles, but not in adult Xenopus, involves blood brain barrier dysfunction. Sci Rep (2016) 0.76
Citrus aurantium increases seizure latency to PTZ induced seizures in zebrafish thru NMDA and mGluR's I and II. Front Pharmacol (2015) 0.75
Developing a Novel Embryo-Larval Zebrafish Xenograft Assay to Prioritize Human Glioblastoma Therapeutics. Zebrafish (2016) 0.75
Potential new complication in drug therapy development for amyotrophic lateral sclerosis. Expert Rev Neurother (2016) 0.75
Variation in wall shear stress in channel networks of zebrafish models. J R Soc Interface (2017) 0.75
Chemical profiling analysis of Maca using UHPLC-ESI-Orbitrap MS coupled with UHPLC-ESI-QqQ MS and the neuroprotective study on its active ingredients. Sci Rep (2017) 0.75
Osmotic pressure-adaptive responses in the eye tissues of rainbow smelt (Osmerus mordax). Mol Vis (2011) 0.75
Pharmacological treatment and BBB-targeted genetic therapy for MCT8-dependent hypomyelination in zebrafish. Dis Model Mech (2016) 0.75
In Vivo Analysis of the Neurovascular Niche in the Developing Xenopus Brain. eNeuro (2017) 0.75
Cerebrospinal fluid injection into adult zebrafish for disease research. J Neural Transm (Vienna) (2017) 0.75
Diel cyclic hypoxia alters plasma lipid dynamics and impairs reproduction in goldfish (Carassius auratus). Fish Physiol Biochem (2017) 0.75
Monitoring Toxic Ionic Liquids in Zebrafish (Danio rerio) with Desorption Electrospray Ionization Mass Spectrometry Imaging (DESI-MSI). J Am Soc Mass Spectrom (2016) 0.75
Zebrafish as a Model Organism for the Development of Drugs for Skin Cancer. Int J Mol Sci (2017) 0.75
Claudin5a is required for proper inflation of Kupffer's vesicle lumen and organ laterality. PLoS One (2017) 0.75
Impact of dehydration on the forebrain preoptic recess walls in the mudskipper, Periophthalmus modestus: a possible locus for the center of thirst. J Comp Physiol B (2016) 0.75
Analyses of pig genomes provide insight into porcine demography and evolution. Nature (2012) 5.58
Multi-platform next-generation sequencing of the domestic turkey (Meleagris gallopavo): genome assembly and analysis. PLoS Biol (2010) 5.39
Inactivation of peroxiredoxin I by phosphorylation allows localized H(2)O(2) accumulation for cell signaling. Cell (2010) 3.82
Hypoxia-inducible factor (HIF-1)alpha: its protein stability and biological functions. Exp Mol Med (2004) 3.04
SSeCKS regulates angiogenesis and tight junction formation in blood-brain barrier. Nat Med (2003) 2.78
Regulation of DUOX by the Galphaq-phospholipase Cbeta-Ca2+ pathway in Drosophila gut immunity. Dev Cell (2009) 1.87
Cellular uptake mechanism and intracellular fate of hydrophobically modified glycol chitosan nanoparticles. J Control Release (2009) 1.81
Sumoylation increases HIF-1alpha stability and its transcriptional activity. Biochem Biophys Res Commun (2004) 1.70
Sestrins activate Nrf2 by promoting p62-dependent autophagic degradation of Keap1 and prevent oxidative liver damage. Cell Metab (2012) 1.65
Blood-neural barrier: intercellular communication at glio-vascular interface. J Biochem Mol Biol (2006) 1.59
Methods for detection and measurement of hydrogen peroxide inside and outside of cells. Mol Cells (2010) 1.46
Jab1 interacts directly with HIF-1alpha and regulates its stability. J Biol Chem (2001) 1.41
Visfatin enhances ICAM-1 and VCAM-1 expression through ROS-dependent NF-kappaB activation in endothelial cells. Biochim Biophys Acta (2008) 1.41
Hypoxia-induced angiogenesis during carcinogenesis. J Biochem Mol Biol (2003) 1.32
Inhibition of hypoxia-induced angiogenesis by FK228, a specific histone deacetylase inhibitor, via suppression of HIF-1alpha activity. Biochem Biophys Res Commun (2003) 1.31
Syntenin is overexpressed and promotes cell migration in metastatic human breast and gastric cancer cell lines. Oncogene (2002) 1.31
Structural basis for depletion of heat shock protein 90 client proteins by deguelin. J Natl Cancer Inst (2007) 1.27
Curcumin inhibits hypoxia-induced angiogenesis via down-regulation of HIF-1. Oncol Rep (2006) 1.26
Hepatitis B virus X protein induces angiogenesis by stabilizing hypoxia-inducible factor-1alpha. FASEB J (2003) 1.25
Genome of a SAR116 bacteriophage shows the prevalence of this phage type in the oceans. Proc Natl Acad Sci U S A (2013) 1.25
ROS-induced ATF3 causes susceptibility to secondary infections during sepsis-associated immunosuppression. Nat Med (2011) 1.21
Ischemia-induced changes in glucagon-like peptide-1 receptor and neuroprotective effect of its agonist, exendin-4, in experimental transient cerebral ischemia. J Neurosci Res (2011) 1.20
Anti-inflammatory effects of chlorogenic acid in lipopolysaccharide-stimulated RAW 264.7 cells. Inflamm Res (2013) 1.20
Visfatin promotes angiogenesis by activation of extracellular signal-regulated kinase 1/2. Biochem Biophys Res Commun (2007) 1.17
Capsaicin inhibits in vitro and in vivo angiogenesis. Cancer Res (2004) 1.16
Dose-dependent biphasic activity of tRNA synthetase-associating factor, p43, in angiogenesis. J Biol Chem (2002) 1.14
Regulation of the HIF-1alpha stability by histone deacetylases. Oncol Rep (2007) 1.13
Hypoxia-induced angiogenesis in human hepatocellular carcinoma. J Mol Med (Berl) (2002) 1.13
Serine 34 phosphorylation of rho guanine dissociation inhibitor (RhoGDIalpha) links signaling from conventional protein kinase C to RhoGTPase in cell adhesion. J Biol Chem (2010) 1.13
Blood-neural barrier: its diversity and coordinated cell-to-cell communication. BMB Rep (2008) 1.12
Histone deacetylase inhibitor FK228 inhibits tumor angiogenesis. Int J Cancer (2002) 1.11
Pro-MMP-2 activation by the PPARgamma agonist, ciglitazone, induces cell invasion through the generation of ROS and the activation of ERK. FEBS Lett (2007) 1.10
Angiopoietin-1 reduces vascular endothelial growth factor-induced brain endothelial permeability via upregulation of ZO-2. Int J Mol Med (2009) 1.09
TNF-related activation-induced cytokine (TRANCE) induces angiogenesis through the activation of Src and phospholipase C (PLC) in human endothelial cells. J Biol Chem (2001) 1.08
Hypoxia-inducible factor-1 alpha inhibits self-renewal of mouse embryonic stem cells in Vitro via negative regulation of the leukemia inhibitory factor-STAT3 pathway. J Biol Chem (2007) 1.08
Carbon monoxide promotes VEGF expression by increasing HIF-1alpha protein level via two distinct mechanisms, translational activation and stabilization of HIF-1alpha protein. J Biol Chem (2010) 1.07
Crosstalk between oligodendrocytes and cerebral endothelium contributes to vascular remodeling after white matter injury. Glia (2012) 1.07
Metastatic tumor antigen 1 is closely associated with frequent postoperative recurrence and poor survival in patients with hepatocellular carcinoma. Hepatology (2008) 1.07
Oxidative stress interferes with white matter renewal after prolonged cerebral hypoperfusion in mice. Stroke (2013) 1.07
HIF-1alpha: a valid therapeutic target for tumor therapy. Cancer Res Treat (2004) 1.06
Protective effect of clusterin from oxidative stress-induced apoptosis in human retinal pigment epithelial cells. Invest Ophthalmol Vis Sci (2009) 1.06
Protective effect of the green tea component, L-theanine on environmental toxins-induced neuronal cell death. Neurotoxicology (2008) 1.06
MST1 limits the kinase activity of aurora B to promote stable kinetochore-microtubule attachment. Curr Biol (2010) 1.06
Brain angiogenesis in developmental and pathological processes: regulation, molecular and cellular communication at the neurovascular interface. FEBS J (2009) 1.05
Genome-wide analysis to predict protein sequence variations that change phosphorylation sites or their corresponding kinases. Nucleic Acids Res (2009) 1.05
Tumor specificity and therapeutic efficacy of photosensitizer-encapsulated glycol chitosan-based nanoparticles in tumor-bearing mice. Biomaterials (2009) 1.05
Coordinated interaction of the vascular and nervous systems: from molecule- to cell-based approaches. Biochem Biophys Res Commun (2003) 1.04
Recruitment of pericytes and astrocytes is closely related to the formation of tight junction in developing retinal vessels. J Neurosci Res (2009) 1.04
Nuclear IL-33 is a transcriptional regulator of NF-κB p65 and induces endothelial cell activation. Biochem Biophys Res Commun (2012) 1.04
Roles of human INO80 chromatin remodeling enzyme in DNA replication and chromosome segregation suppress genome instability. Cell Mol Life Sci (2010) 1.04
Oligodendrocyte precursors induce early blood-brain barrier opening after white matter injury. J Clin Invest (2013) 1.02
Identification of novel antiangiogenic anticancer activities of deguelin targeting hypoxia-inducible factor-1 alpha. Int J Cancer (2008) 1.02
Neuronal genes for subcutaneous fat thickness in human and pig are identified by local genomic sequencing and combined SNP association study. PLoS One (2011) 1.02
Intravenously administered gold nanoparticles pass through the blood-retinal barrier depending on the particle size, and induce no retinal toxicity. Nanotechnology (2009) 1.01
Metastasis-associated protein 1 enhances angiogenesis by stabilization of HIF-1alpha. Oncol Rep (2006) 1.01
Characterization of ARD1 variants in mammalian cells. Biochem Biophys Res Commun (2005) 1.01
Age-related decline in oligodendrogenesis retards white matter repair in mice. Stroke (2013) 1.01
Nerve injury-induced protein 1 (Ninjurin-1) is a novel therapeutic target for cavernous nerve injury-induced erectile dysfunction in mice. J Sex Med (2013) 1.00
Synthetic curcumin analogs inhibit activator protein-1 transcription and tumor-induced angiogenesis. Biochem Biophys Res Commun (2004) 0.99
Ninjurin1 is expressed in myeloid cells and mediates endothelium adhesion in the brains of EAE rats. Biochem Biophys Res Commun (2009) 0.99
Functional importance of the anaphase-promoting complex-Cdh1-mediated degradation of TMAP/CKAP2 in regulation of spindle function and cytokinesis. Mol Cell Biol (2007) 0.99
Osteopontin splice variants differentially modulate the migratory activity of hepatocellular carcinoma cell lines. Int J Oncol (2009) 0.98
The role of clusterin in in vitro ischemia of human retinal endothelial cells. Curr Eye Res (2007) 0.98
Arrest defective 1 autoacetylation is a critical step in its ability to stimulate cancer cell proliferation. Cancer Res (2010) 0.97
AKAP12 regulates human blood-retinal barrier formation by downregulation of hypoxia-inducible factor-1alpha. J Neurosci (2007) 0.97
Inhibition of protein kinase C delta attenuates blood-retinal barrier breakdown in diabetic retinopathy. Am J Pathol (2010) 0.97
Homoisoflavanone inhibits retinal neovascularization through cell cycle arrest with decrease of cdc2 expression. Biochem Biophys Res Commun (2007) 0.96
Neurovascular matrix metalloproteinases and the blood-brain barrier. Curr Pharm Des (2012) 0.96
Meteorin promotes the formation of GFAP-positive glia via activation of the Jak-STAT3 pathway. J Cell Sci (2010) 0.96
High-resolution three-photon biomedical imaging using doped ZnS nanocrystals. Nat Mater (2013) 0.95
The anti-angiogenic activities of glycyrrhizic acid in tumor progression. Phytother Res (2012) 0.95
Establishment and characterization of a novel, spontaneously immortalized retinoblastoma cell line with adherent growth. Int J Oncol (2007) 0.95
Hypoxic priming of mESCs accelerates vascular-lineage differentiation through HIF1-mediated inverse regulation of Oct4 and VEGF. EMBO Mol Med (2012) 0.94
Protein kinase C-delta regulates the stability of hypoxia-inducible factor-1 alpha under hypoxia. Cancer Sci (2007) 0.94
Aminopeptidase N/CD13 induces angiogenesis through interaction with a pro-angiogenic protein, galectin-3. Biochem Biophys Res Commun (2007) 0.94
Blockade of angiotensin II attenuates VEGF-mediated blood-retinal barrier breakdown in diabetic retinopathy. J Cereb Blood Flow Metab (2008) 0.94
Tid-1 interacts with the von Hippel-Lindau protein and modulates angiogenesis by destabilization of HIF-1alpha. Cancer Res (2005) 0.94
CAGE, a novel cancer/testis antigen gene, promotes cell motility by activation ERK and p38 MAPK and downregulating ROS. Mol Cells (2006) 0.93
AKAP12 induces apoptotic cell death in human fibrosarcoma cells by regulating CDKI-cyclin D1 and caspase-3 activity. Cancer Lett (2007) 0.93
A genome-wide identification of genes potentially associated with host specificity of Brucella species. J Microbiol (2011) 0.93
A novel derivative of the natural agent deguelin for cancer chemoprevention and therapy. Cancer Prev Res (Phila) (2008) 0.92
Blood-brain barrier interfaces and brain tumors. Arch Pharm Res (2006) 0.92
Regulation of Egr-1 by association with the proteasome component C8. Biochim Biophys Acta (2002) 0.92
Meteorin regulates angiogenesis at the gliovascular interface. Glia (2008) 0.92
Differential profiles of microRNAs in retinoblastoma cell lines of different proliferation and adherence patterns. J Pediatr Hematol Oncol (2011) 0.91
Quantification of cellular uptake and in vivo tracking of transduction using real-time monitoring. Biochem Biophys Res Commun (2010) 0.91
Negative regulation of hypoxia inducible factor-1alpha by necdin. FEBS Lett (2005) 0.91
Clusterin protects H9c2 cardiomyocytes from oxidative stress-induced apoptosis via Akt/GSK-3β signaling pathway. Exp Mol Med (2011) 0.91
Effects of ADHD therapeutic agents, methylphenidate and atomoxetine, on hippocampal neurogenesis in the adolescent mouse dentate gyrus. Neurosci Lett (2012) 0.91