Published in J Clin Invest on January 02, 2013
The pathobiology of vascular dementia. Neuron (2013) 3.07
Reactive gliosis and the multicellular response to CNS damage and disease. Neuron (2014) 2.08
Hypertension: a harbinger of stroke and dementia. Hypertension (2013) 1.30
Rapid endothelial cytoskeletal reorganization enables early blood-brain barrier disruption and long-term ischaemic reperfusion brain injury. Nat Commun (2016) 1.14
Oxidative stress interferes with white matter renewal after prolonged cerebral hypoperfusion in mice. Stroke (2013) 1.07
NG2 cells (polydendrocytes) in brain physiology and repair. Front Neurosci (2014) 1.01
White Matter Injury After Subarachnoid Hemorrhage: Role of Blood-Brain Barrier Disruption and Matrix Metalloproteinase-9. Stroke (2015) 0.90
Oligodendrocyte precursor cells support blood-brain barrier integrity via TGF-β signaling. PLoS One (2014) 0.89
Crosstalk between cerebral endothelium and oligodendrocyte. Cell Mol Life Sci (2013) 0.86
Abrogation of β-catenin signaling in oligodendrocyte precursor cells reduces glial scarring and promotes axon regeneration after CNS injury. J Neurosci (2014) 0.85
Influence of the extracellular matrix on endogenous and transplanted stem cells after brain damage. Front Cell Neurosci (2014) 0.83
Blood-brain barrier dysfunction and cerebral small vessel disease (arteriolosclerosis) in brains of older people. J Neuropathol Exp Neurol (2014) 0.79
Subcortical ischemic vascular disease: Roles of oligodendrocyte function in experimental models of subcortical white-matter injury. J Cereb Blood Flow Metab (2016) 0.79
Neuroprotective effects of oligodendrocyte progenitor cell transplantation in premature rat brain following hypoxic-ischemic injury. PLoS One (2015) 0.78
A radical scavenger edaravone inhibits matrix metalloproteinase-9 upregulation and blood-brain barrier breakdown in a mouse model of prolonged cerebral hypoperfusion. Neurosci Lett (2014) 0.78
Potential interactions between pericytes and oligodendrocyte precursor cells in perivascular regions of cerebral white matter. Neurosci Lett (2015) 0.78
The reactions and role of NG2 glia in spinal cord injury. Brain Res (2015) 0.78
First translational 'Think Tank' on cerebrovascular disease, cognitive impairment and dementia. J Transl Med (2016) 0.77
Neuroimaging Biomarkers Predict Brain Structural Connectivity Change in a Mouse Model of Vascular Cognitive Impairment. Stroke (2017) 0.77
The impact of cerebrovascular aging on vascular cognitive impairment and dementia. Ageing Res Rev (2016) 0.77
Heterogeneity of astrocyte and NG2 cell insertion at the node of ranvier. J Comp Neurol (2016) 0.75
The future of stem cell therapy for stroke rehabilitation. Future Neurol (2015) 0.75
Adult oligodendrocyte progenitor cells - Multifaceted regulators of the CNS in health and disease. Brain Behav Immun (2016) 0.75
Gas6 Promotes Oligodendrogenesis and Myelination in the Adult Central Nervous System and After Lysolecithin-Induced Demyelination. ASN Neuro (2016) 0.75
Endothelial cell-oligodendrocyte interactions in small vessel disease and aging. Clin Sci (Lond) (2017) 0.75
Mechanisms of cellular plasticity in cerebral perivascular region. Prog Brain Res (2016) 0.75
Hyper-oligodendrogenesis at the vascular niche and reduced blood-brain barrier integrity in the prefrontal cortex during protracted abstinence. Neuroscience (2017) 0.75
Regeneration beyond the glial scar. Nat Rev Neurosci (2004) 11.00
The science of stroke: mechanisms in search of treatments. Neuron (2010) 6.14
PDGFRA/NG2 glia generate myelinating oligodendrocytes and piriform projection neurons in adult mice. Nat Neurosci (2008) 5.25
Effects of matrix metalloproteinase-9 gene knock-out on the proteolysis of blood-brain barrier and white matter components after cerebral ischemia. J Neurosci (2001) 4.99
CNS injury, glial scars, and inflammation: Inhibitory extracellular matrices and regeneration failure. Exp Neurol (2007) 4.00
Polydendrocytes (NG2 cells): multifunctional cells with lineage plasticity. Nat Rev Neurosci (2009) 3.72
Matrix metalloproteinases and TIMPs are associated with blood-brain barrier opening after reperfusion in rat brain. Stroke (1998) 3.58
Matrix metalloproteinase expression increases after cerebral focal ischemia in rats: inhibition of matrix metalloproteinase-9 reduces infarct size. Stroke (1998) 3.03
The role of microglia in the healthy brain. J Neurosci (2011) 2.94
Endogenous progenitors remyelinate demyelinated axons in the adult CNS. Neuron (1997) 2.93
Innate immunity in the central nervous system. J Clin Invest (2012) 2.77
Essential protective roles of reactive astrocytes in traumatic brain injury. Brain (2006) 2.75
Blood-brain barrier breakdown in acute and chronic cerebrovascular disease. Stroke (2011) 2.37
White matter lesions and glial activation in a novel mouse model of chronic cerebral hypoperfusion. Stroke (2004) 2.29
Microglial activation in stroke: therapeutic targets. Neurotherapeutics (2010) 1.84
Vascular cognitive impairment. Nat Clin Pract Neurol (2006) 1.64
An oligovascular niche: cerebral endothelial cells promote the survival and proliferation of oligodendrocyte precursor cells. J Neurosci (2009) 1.62
Promoting brain remodelling and plasticity for stroke recovery: therapeutic promise and potential pitfalls of clinical translation. Lancet Neurol (2012) 1.60
Barriers in the brain: a renaissance? Trends Neurosci (2008) 1.49
In vivo proliferation of oligodendrocyte progenitors expressing PDGFalphaR during early remyelination. J Neurobiol (1998) 1.48
Neurodegeneration and the neurovascular unit. Nat Med (2010) 1.37
Oligodendrocytes as providers of growth factors. J Neurosci Res (2002) 1.29
Increasing tPA activity in astrocytes induced by multipotent mesenchymal stromal cells facilitate neurite outgrowth after stroke in the mouse. PLoS One (2010) 1.28
Phosphodiesterase III inhibition promotes differentiation and survival of oligodendrocyte progenitors and enhances regeneration of ischemic white matter lesions in the adult mammalian brain. J Cereb Blood Flow Metab (2009) 1.02
Activation of NG2-positive oligodendrocyte progenitor cells during post-ischemic reperfusion in the rat brain. Neuroreport (2001) 0.99
Update of the stroke therapy academic industry roundtable preclinical recommendations. Stroke (2009) 6.79
The science of stroke: mechanisms in search of treatments. Neuron (2010) 6.14
Analyses of pig genomes provide insight into porcine demography and evolution. Nature (2012) 5.58
Multi-platform next-generation sequencing of the domestic turkey (Meleagris gallopavo): genome assembly and analysis. PLoS Biol (2010) 5.39
Role of matrix metalloproteinases in delayed cortical responses after stroke. Nat Med (2006) 5.10
Distinct roles of matrix metalloproteases in the early- and late-phase development of neuropathic pain. Nat Med (2008) 3.83
Lipoprotein receptor-mediated induction of matrix metalloproteinase by tissue plasminogen activator. Nat Med (2003) 3.10
Nutrient-sensitized screening for drugs that shift energy metabolism from mitochondrial respiration to glycolysis. Nat Biotechnol (2010) 3.08
Hypoxia-inducible factor (HIF-1)alpha: its protein stability and biological functions. Exp Mol Med (2004) 3.04
SSeCKS regulates angiogenesis and tight junction formation in blood-brain barrier. Nat Med (2003) 2.78
A computerized algorithm for etiologic classification of ischemic stroke: the Causative Classification of Stroke System. Stroke (2007) 2.63
A pilot study of normobaric oxygen therapy in acute ischemic stroke. Stroke (2005) 2.58
Two-photon high-resolution measurement of partial pressure of oxygen in cerebral vasculature and tissue. Nat Methods (2010) 2.37
Vasoconstrictive neurovascular coupling during focal ischemic depolarizations. J Cereb Blood Flow Metab (2005) 2.32
Involvement of matrix metalloproteinase in thrombolysis-associated hemorrhagic transformation after embolic focal ischemia in rats. Stroke (2002) 2.30
Increased brain expression of matrix metalloproteinase-9 after ischemic and hemorrhagic human stroke. Stroke (2006) 2.27
Effects of neuroglobin overexpression on acute brain injury and long-term outcomes after focal cerebral ischemia. Stroke (2008) 2.25
Upper limb ischemic preconditioning prevents recurrent stroke in intracranial arterial stenosis. Neurology (2012) 2.19
Mechanisms of hemorrhagic transformation after tissue plasminogen activator reperfusion therapy for ischemic stroke. Stroke (2004) 2.13
Extension of the thrombolytic time window with minocycline in experimental stroke. Stroke (2008) 2.10
Neuroprotection via matrix-trophic coupling between cerebral endothelial cells and neurons. Proc Natl Acad Sci U S A (2008) 2.06
Correlation between brain reorganization, ischemic damage, and neurologic status after transient focal cerebral ischemia in rats: a functional magnetic resonance imaging study. J Neurosci (2003) 2.05
Cortical spreading depression activates and upregulates MMP-9. J Clin Invest (2004) 1.93
Normobaric hyperoxia improves cerebral blood flow and oxygenation, and inhibits peri-infarct depolarizations in experimental focal ischaemia. Brain (2007) 1.92
Cell-cell signaling in the neurovascular unit. Neurochem Res (2007) 1.92
Stimulus-induced changes in blood flow and 2-deoxyglucose uptake dissociate in ipsilateral somatosensory cortex. J Neurosci (2008) 1.89
ADAMTS13 gene deletion aggravates ischemic brain damage: a possible neuroprotective role of ADAMTS13 by ameliorating postischemic hypoperfusion. Blood (2009) 1.89
Involvement of matrix metalloproteinase in neuroblast cell migration from the subventricular zone after stroke. J Neurosci (2006) 1.85
Brain angiogenesis in developmental and pathological processes: neurovascular injury and angiogenic recovery after stroke. FEBS J (2009) 1.82
Genetic and hormonal factors modulate spreading depression and transient hemiparesis in mouse models of familial hemiplegic migraine type 1. J Clin Invest (2008) 1.81
The neurotoxicity of tissue plasminogen activator? J Cereb Blood Flow Metab (2004) 1.80
Multiphasic roles for matrix metalloproteinases after stroke. Curr Opin Pharmacol (2008) 1.79
Tissue plasminogen activator promotes matrix metalloproteinase-9 upregulation after focal cerebral ischemia. Stroke (2005) 1.77
Sumoylation increases HIF-1alpha stability and its transcriptional activity. Biochem Biophys Res Commun (2004) 1.70
The phosphorylation state of eNOS modulates vascular reactivity and outcome of cerebral ischemia in vivo. J Clin Invest (2007) 1.67
Normobaric hyperoxia reduces MRI diffusion abnormalities and infarct size in experimental stroke. Neurology (2002) 1.67
Developmentally regulated role for Ras-GRFs in coupling NMDA glutamate receptors to Ras, Erk and CREB. EMBO J (2004) 1.65
An oligovascular niche: cerebral endothelial cells promote the survival and proliferation of oligodendrocyte precursor cells. J Neurosci (2009) 1.62
Fingolimod provides long-term protection in rodent models of cerebral ischemia. Ann Neurol (2010) 1.62
Beyond NMDA and AMPA glutamate receptors: emerging mechanisms for ionic imbalance and cell death in stroke. Trends Pharmacol Sci (2008) 1.62
Green tea polyphenol (-)-epigallocatechin gallate reduces neuronal cell damage and up-regulation of MMP-9 activity in hippocampal CA1 and CA2 areas following transient global cerebral ischemia. J Neurosci Res (2009) 1.60
Effects of normobaric hyperoxia in a rat model of focal cerebral ischemia-reperfusion. J Cereb Blood Flow Metab (2002) 1.59
Blood-neural barrier: intercellular communication at glio-vascular interface. J Biochem Mol Biol (2006) 1.59
Mild induced hypertension improves blood flow and oxygen metabolism in transient focal cerebral ischemia. Stroke (2008) 1.58
OCT methods for capillary velocimetry. Biomed Opt Express (2012) 1.57
Role of matrix metalloproteinases in delayed neuronal damage after transient global cerebral ischemia. J Neurosci (2004) 1.56
Astrocytic induction of matrix metalloproteinase-9 and edema in brain hemorrhage. J Cereb Blood Flow Metab (2006) 1.56
Age-dependent cerebrovascular dysfunction in a transgenic mouse model of cerebral amyloid angiopathy. Brain (2007) 1.55
Junctional complexes of the blood-brain barrier: permeability changes in neuroinflammation. Prog Neurobiol (2002) 1.55
Functional and developmental analysis of the blood-brain barrier in zebrafish. Brain Res Bull (2007) 1.51
Baicalein and 12/15-lipoxygenase in the ischemic brain. Stroke (2006) 1.50
Experimental model of warfarin-associated intracerebral hemorrhage. Stroke (2008) 1.48
Granulocyte colony-stimulating factor enhances angiogenesis after focal cerebral ischemia. Brain Res (2005) 1.47
Neurovascular proteases in brain injury, hemorrhage and remodeling after stroke. Stroke (2007) 1.47
Simultaneous multispectral reflectance imaging and laser speckle flowmetry of cerebral blood flow and oxygen metabolism in focal cerebral ischemia. J Biomed Opt (2008) 1.46
Microemboli may link spreading depression, migraine aura, and patent foramen ovale. Ann Neurol (2010) 1.45
Annexin A2 combined with low-dose tPA improves thrombolytic therapy in a rat model of focal embolic stroke. J Cereb Blood Flow Metab (2010) 1.44
Hemoglobin-induced cytotoxicity in rat cerebral cortical neurons: caspase activation and oxidative stress. Stroke (2002) 1.43
Normobaric hyperoxia extends the reperfusion window in focal cerebral ischemia. Ann Neurol (2005) 1.42
Simultaneous imaging of cerebral partial pressure of oxygen and blood flow during functional activation and cortical spreading depression. Appl Opt (2009) 1.41
Jab1 interacts directly with HIF-1alpha and regulates its stability. J Biol Chem (2001) 1.41
Visfatin enhances ICAM-1 and VCAM-1 expression through ROS-dependent NF-kappaB activation in endothelial cells. Biochim Biophys Acta (2008) 1.41
Triggers and mediators of hemorrhagic transformation in cerebral ischemia. Mol Neurobiol (2003) 1.40
Exendin-4, a glucagon-like peptide-1 receptor agonist, provides neuroprotection in mice transient focal cerebral ischemia. J Cereb Blood Flow Metab (2011) 1.40
Biphasic actions of HMGB1 signaling in inflammation and recovery after stroke. Ann N Y Acad Sci (2010) 1.39
Relaxation-compensated fast multislice amide proton transfer (APT) imaging of acute ischemic stroke. Magn Reson Med (2008) 1.39
Association between pH-weighted endogenous amide proton chemical exchange saturation transfer MRI and tissue lactic acidosis during acute ischemic stroke. J Cereb Blood Flow Metab (2011) 1.36
Oxidative stress and matrix metalloproteinase-9 in acute ischemic stroke: the Biomarker Evaluation for Antioxidant Therapies in Stroke (BEAT-Stroke) study. Stroke (2007) 1.35
Optical coherence tomography for the quantitative study of cerebrovascular physiology. J Cereb Blood Flow Metab (2011) 1.35
Novel lipoxygenase inhibitors as neuroprotective reagents. J Neurosci Res (2008) 1.34
Cerebral hypoperfusion accelerates cerebral amyloid angiopathy and promotes cortical microinfarcts. Acta Neuropathol (2011) 1.34
Essential role for ERK mitogen-activated protein kinase in matrix metalloproteinase-9 regulation in rat cortical astrocytes. Glia (2003) 1.32
Hypoxia-induced angiogenesis during carcinogenesis. J Biochem Mol Biol (2003) 1.32
Rho-kinase inhibition acutely augments blood flow in focal cerebral ischemia via endothelial mechanisms. J Cereb Blood Flow Metab (2006) 1.32
Inhibition of hypoxia-induced angiogenesis by FK228, a specific histone deacetylase inhibitor, via suppression of HIF-1alpha activity. Biochem Biophys Res Commun (2003) 1.31
Syntenin is overexpressed and promotes cell migration in metastatic human breast and gastric cancer cell lines. Oncogene (2002) 1.31
High-mobility group box 1 promotes metalloproteinase-9 upregulation through Toll-like receptor 4 after cerebral ischemia. Stroke (2010) 1.30
Dysfunctional cell-cell signaling in the neurovascular unit as a paradigm for central nervous system disease. Stroke (2008) 1.29
Migraine mutations increase stroke vulnerability by facilitating ischemic depolarizations. Circulation (2011) 1.28
Linking Notch signaling to ischemic stroke. Proc Natl Acad Sci U S A (2008) 1.28
Structural basis for depletion of heat shock protein 90 client proteins by deguelin. J Natl Cancer Inst (2007) 1.27
Inhibition of reactive astrocytes with fluorocitrate retards neurovascular remodeling and recovery after focal cerebral ischemia in mice. J Cereb Blood Flow Metab (2009) 1.27
Acute plasmalemma permeability and protracted clearance of injured cells after controlled cortical impact in mice. J Cereb Blood Flow Metab (2007) 1.27
Fukutin is required for maintenance of muscle integrity, cortical histiogenesis and normal eye development. Hum Mol Genet (2003) 1.27
Curcumin inhibits hypoxia-induced angiogenesis via down-regulation of HIF-1. Oncol Rep (2006) 1.26
Plasma and brain matrix metalloproteinase-9 after acute focal cerebral ischemia in rats. Stroke (2009) 1.26
Effects of neuroglobin overexpression on mitochondrial function and oxidative stress following hypoxia/reoxygenation in cultured neurons. J Neurosci Res (2009) 1.25
Protecting against cerebrovascular injury: contributions of 12/15-lipoxygenase to edema formation after transient focal ischemia. Stroke (2008) 1.25
Hepatitis B virus X protein induces angiogenesis by stabilizing hypoxia-inducible factor-1alpha. FASEB J (2003) 1.25
Astrocytic high-mobility group box 1 promotes endothelial progenitor cell-mediated neurovascular remodeling during stroke recovery. Proc Natl Acad Sci U S A (2012) 1.24