Published in Eur J Immunol on August 01, 2008
Reductive isolation from bone marrow and blood implicates common lymphoid progenitors as the major source of thymopoiesis. Blood (2008) 1.86
Dedifferentiating spermatogonia outcompete somatic stem cells for niche occupancy in the Drosophila testis. Cell Stem Cell (2009) 1.61
The biology of allogeneic hematopoietic cell resistance. Biol Blood Marrow Transplant (2009) 0.85
Murine Models of Transplantation Tolerance through Mixed Chimerism: Advances and Roadblocks. Clin Exp Immunol (2017) 0.83
Expression of TCR-Vβ peptides by murine bone marrow cells does not identify T-cell progenitors. J Cell Mol Med (2015) 0.76
A clonogenic common myeloid progenitor that gives rise to all myeloid lineages. Nature (2000) 16.75
Identification of clonogenic common lymphoid progenitors in mouse bone marrow. Cell (1997) 12.60
Long-term lymphohematopoietic reconstitution by a single CD34-low/negative hematopoietic stem cell. Science (1996) 12.54
Hematopoietic stem-cell transplantation. N Engl J Med (2006) 10.45
Stem cells and niches: mechanisms that promote stem cell maintenance throughout life. Cell (2008) 9.92
Physiological migration of hematopoietic stem and progenitor cells. Science (2001) 7.02
Elucidation of the phenotypic, functional, and molecular topography of a myeloerythroid progenitor cell hierarchy. Cell Stem Cell (2007) 5.28
Immunosurveillance by hematopoietic progenitor cells trafficking through blood, lymph, and peripheral tissues. Cell (2007) 5.17
Thymopoiesis independent of common lymphoid progenitors. Nat Immunol (2003) 4.52
Immunological reconstitution of sex-linked lymphopenic immunological deficiency. Lancet (1968) 4.41
Thrombopoietin/MPL signaling regulates hematopoietic stem cell quiescence and interaction with the osteoblastic niche. Cell Stem Cell (2007) 4.31
Graft-versus-host disease. Nat Rev Immunol (2007) 4.26
Mobilization of hematopoietic progenitor cells in healthy volunteers by AMD3100, a CXCR4 antagonist. Blood (2003) 4.19
Transcription from the RAG1 locus marks the earliest lymphocyte progenitors in bone marrow. Immunity (2002) 3.69
Identification of a hierarchy of multipotent hematopoietic progenitors in human cord blood. Cell Stem Cell (2007) 3.59
Isolation of murine pluripotent hemopoietic stem cells. J Exp Med (1984) 3.56
Human T, B, natural killer, and dendritic cells arise from a common bone marrow progenitor cell subset. Immunity (1995) 3.51
Prospective isolation of human clonogenic common myeloid progenitors. Proc Natl Acad Sci U S A (2002) 3.50
The earliest thymic progenitors for T cells possess myeloid lineage potential. Nature (2008) 3.48
Long-term survival and transplantation of haemopoietic stem cells for immunodeficiencies: report of the European experience 1968-99. Lancet (2003) 3.44
Adult T-cell progenitors retain myeloid potential. Nature (2008) 3.41
Intravenous infusion of bone marrow in patients receiving radiation and chemotherapy. N Engl J Med (1957) 3.40
Long-term engraftment of normal and post-5-fluorouracil murine marrow into normal nonmyeloablated mice. Blood (1993) 3.08
Early hematopoietic lineage restrictions directed by Ikaros. Nat Immunol (2006) 2.82
Dendritic cell potentials of early lymphoid and myeloid progenitors. Blood (2001) 2.75
Efficient transplantation via antibody-based clearance of hematopoietic stem cell niches. Science (2007) 2.69
Reciprocal activation of GATA-1 and PU.1 marks initial specification of hematopoietic stem cells into myeloerythroid and myelolymphoid lineages. Cell Stem Cell (2007) 2.57
Commitment and developmental potential of extrathymic and intrathymic T cell precursors: plenty to choose from. Immunity (2007) 2.51
Dynamic regulation of PU.1 expression in multipotent hematopoietic progenitors. J Exp Med (2005) 2.39
Flk2+ common lymphoid progenitors possess equivalent differentiation potential for the B and T lineages. Blood (2008) 2.06
Selective thymus settling regulated by cytokine and chemokine receptors. J Immunol (2007) 1.92
Adoptive transfer of T-cell precursors enhances T-cell reconstitution after allogeneic hematopoietic stem cell transplantation. Nat Med (2006) 1.85
Thymocytopoiesis is maintained by blood-borne precursors throughout postnatal life. A study in parabiotic mice. J Immunol (1992) 1.84
Purified hematopoietic stem cell engraftment of rare niches corrects severe lymphoid deficiencies without host conditioning. J Exp Med (2005) 1.77
Characterization of c-kit positive intrathymic stem cells that are restricted to lymphoid differentiation. J Exp Med (1993) 1.75
Hematopoietic stem cell quiescence attenuates DNA damage response and permits DNA damage accumulation during aging. Cell Cycle (2007) 1.69
Fate of chromosome-marked mouse bone marrow cells tranfused into normal syngeneic recipients. Transplantation (1968) 1.64
Identification of a novel, human multilymphoid progenitor in cord blood. Blood (2001) 1.56
A common pathway for dendritic cell and early B cell development. J Immunol (2001) 1.50
Lineage infidelity in myeloid cells with TCR gene rearrangement: a latent developmental potential of proT cells revealed by ectopic cytokine receptor signaling. Proc Natl Acad Sci U S A (2002) 1.49
Transplantation of purified hematopoietic stem cells: requirements for overcoming the barriers of allogeneic engraftment. Biol Blood Marrow Transplant (1996) 1.48
Transplantation of highly purified CD34+Thy-1+ hematopoietic stem cells in patients with metastatic breast cancer. Biol Blood Marrow Transplant (2000) 1.48
Identification of a bone marrow precursor of the earliest thymocytes in adult mouse. Proc Natl Acad Sci U S A (2007) 1.47
T cell repertoire development in humans with SCID after nonablative allogeneic marrow transplantation. J Immunol (2003) 1.39
Primitive lymphoid progenitors in bone marrow with T lineage reconstituting potential. J Immunol (2006) 1.33
Transplantation potential of peripheral blood stem cells induced by granulocyte colony-stimulating factor. Blood (1990) 1.30
Effect of recent antigen priming on adoptive immune responses. III. Antigen-induced selective recruitment of subsets of recirculating lymphocytes reactive to H-2 determinants. J Exp Med (1976) 1.30
Prospective isolation and global gene expression analysis of the erythrocyte colony-forming unit (CFU-E). Blood (2004) 1.26
Special proliferative sites are not needed for seeding and proliferation of transfused bone marrow cells in normal syngeneic mice. Proc Natl Acad Sci U S A (1982) 1.25
Early determinants of long-term T-cell reconstitution after hematopoietic stem cell transplantation for severe combined immunodeficiency. Blood (2006) 1.22
Myeloid progenitors protect against invasive aspergillosis and Pseudomonas aeruginosa infection following hematopoietic stem cell transplantation. Blood (2002) 1.21
A human postnatal lymphoid progenitor capable of circulating and seeding the thymus. J Exp Med (2007) 1.21
Common lymphoid progenitors rapidly engraft and protect against lethal murine cytomegalovirus infection after hematopoietic stem cell transplantation. Blood (2003) 1.19
Molecular characterization of early human T/NK and B-lymphoid progenitor cells in umbilical cord blood. Blood (2004) 1.17
Characterization of thymus-seeding precursor cells from mouse bone marrow. Blood (2001) 1.12
Phenotypic plasticity of T cell progenitors upon exposure to Notch ligands. J Exp Med (2006) 1.07
Transplantation of chromosomally marked syngeneic marrow cells into mice not subjected to hematopoietic stem cell depletion. Exp Hematol (1984) 0.98
Hematopoietic stem cells engraft in untreated transplant recipients. Exp Hematol (1993) 0.94
Antibody-facilitated chimeras. Stem cell allotransplantation using antihost major histocompatibility complex monoclonal antibodies instead of lethal irradiation for host conditioning. Transplantation (1984) 0.94
Protection against lethal Aspergillus fumigatus infection in mice by allogeneic myeloid progenitors is not major histocompatibility complex restricted. J Infect Dis (2005) 0.86
Tolerance of engrafted donor T cells following bone marrow transplantation for severe combined immunodeficiency. Clin Immunol Immunopathol (1988) 0.86
Graft-versus-host disease: a surge of developments. PLoS Med (2007) 0.84
Single infusion of myeloid progenitors reduces death from Aspergillus fumigatus following chemotherapy-induced neutropenia. Blood (2004) 0.83
A SCID patient reconstituted with HLA-incompatible fetal stem cells as a model for studying transplantation tolerance. Blood Cells (1991) 0.76
Conditioning regimens for allogeneic bone marrow transplantation. Blood Rev (1992) 0.76
Cancer stem cells--perspectives on current status and future directions: AACR Workshop on cancer stem cells. Cancer Res (2006) 17.42
Bmi-1 is required for maintenance of adult self-renewing haematopoietic stem cells. Nature (2003) 14.35
A role for Wnt signalling in self-renewal of haematopoietic stem cells. Nature (2003) 12.81
Wnt proteins are lipid-modified and can act as stem cell growth factors. Nature (2003) 12.54
Granulocyte-macrophage progenitors as candidate leukemic stem cells in blast-crisis CML. N Engl J Med (2004) 11.29
Rejuvenation of aged progenitor cells by exposure to a young systemic environment. Nature (2005) 11.23
Association of reactive oxygen species levels and radioresistance in cancer stem cells. Nature (2009) 10.31
Little evidence for developmental plasticity of adult hematopoietic stem cells. Science (2002) 9.63
Haematopoietic stem cells adopt mature haematopoietic fates in ischaemic myocardium. Nature (2004) 8.36
Biology of hematopoietic stem cells and progenitors: implications for clinical application. Annu Rev Immunol (2002) 7.78
Deficiencies in DNA damage repair limit the function of haematopoietic stem cells with age. Nature (2007) 7.72
Langerhans cells renew in the skin throughout life under steady-state conditions. Nat Immunol (2002) 7.03
Cell intrinsic alterations underlie hematopoietic stem cell aging. Proc Natl Acad Sci U S A (2005) 6.32
Comprehensive methylome map of lineage commitment from haematopoietic progenitors. Nature (2010) 6.06
Stems cells and the pathways to aging and cancer. Cell (2008) 5.99
Global analysis of proliferation and cell cycle gene expression in the regulation of hematopoietic stem and progenitor cell fates. J Exp Med (2005) 5.68
CD47 is an adverse prognostic factor and therapeutic antibody target on human acute myeloid leukemia stem cells. Cell (2009) 5.30
Elucidation of the phenotypic, functional, and molecular topography of a myeloerythroid progenitor cell hierarchy. Cell Stem Cell (2007) 5.28
CD47 is upregulated on circulating hematopoietic stem cells and leukemia cells to avoid phagocytosis. Cell (2009) 5.22
Transcription factor profiling in individual hematopoietic progenitors by digital RT-PCR. Proc Natl Acad Sci U S A (2006) 5.21
Isolation of adult mouse myogenic progenitors: functional heterogeneity of cells within and engrafting skeletal muscle. Cell (2004) 5.20
Plasticity of adult stem cells. Cell (2004) 5.13
Human melanoma-initiating cells express neural crest nerve growth factor receptor CD271. Nature (2010) 5.05
Similar MLL-associated leukemias arising from self-renewing stem cells and short-lived myeloid progenitors. Genes Dev (2003) 4.71
In vivo visualization of embryonic stem cell survival, proliferation, and migration after cardiac delivery. Circulation (2006) 4.48
Shifting foci of hematopoiesis during reconstitution from single stem cells. Proc Natl Acad Sci U S A (2003) 4.41
Myeloid or lymphoid promiscuity as a critical step in hematopoietic lineage commitment. Dev Cell (2002) 4.37
Hematopoietic stem cells: the paradigmatic tissue-specific stem cell. Am J Pathol (2006) 4.32
JunB deficiency leads to a myeloproliferative disorder arising from hematopoietic stem cells. Cell (2004) 4.28
The CD47-signal regulatory protein alpha (SIRPa) interaction is a therapeutic target for human solid tumors. Proc Natl Acad Sci U S A (2012) 4.20
Normal and leukemic hematopoiesis: are leukemias a stem cell disorder or a reacquisition of stem cell characteristics? Proc Natl Acad Sci U S A (2003) 4.09
Clonal evolution of preleukemic hematopoietic stem cells precedes human acute myeloid leukemia. Sci Transl Med (2012) 4.05
Coronary arteries form by developmental reprogramming of venous cells. Nature (2010) 3.95
Cancer stem cells in solid tumors. Curr Opin Biotechnol (2007) 3.91
Endochondral ossification is required for haematopoietic stem-cell niche formation. Nature (2008) 3.87
Identification, molecular characterization, clinical prognosis, and therapeutic targeting of human bladder tumor-initiating cells. Proc Natl Acad Sci U S A (2009) 3.87
Sustained in vitro intestinal epithelial culture within a Wnt-dependent stem cell niche. Nat Med (2009) 3.82
Tracking single hematopoietic stem cells in vivo using high-throughput sequencing in conjunction with viral genetic barcoding. Nat Biotechnol (2011) 3.81
Flt3 ligand regulates dendritic cell development from Flt3+ lymphoid and myeloid-committed progenitors to Flt3+ dendritic cells in vivo. J Exp Med (2003) 3.74
Identification of a hierarchy of multipotent hematopoietic progenitors in human cord blood. Cell Stem Cell (2007) 3.59
Prospective isolation of human clonogenic common myeloid progenitors. Proc Natl Acad Sci U S A (2002) 3.50
Functionally distinct hematopoietic stem cells modulate hematopoietic lineage potential during aging by a mechanism of clonal expansion. Proc Natl Acad Sci U S A (2010) 3.41
Preleukemic mutations in human acute myeloid leukemia affect epigenetic regulators and persist in remission. Proc Natl Acad Sci U S A (2014) 3.39
Anti-CD47 antibody synergizes with rituximab to promote phagocytosis and eradicate non-Hodgkin lymphoma. Cell (2010) 3.37
Bone marrow-derived circulating endothelial precursors do not contribute to vascular endothelium and are not needed for tumor growth. Proc Natl Acad Sci U S A (2008) 3.27
Engineered SIRPα variants as immunotherapeutic adjuvants to anticancer antibodies. Science (2013) 3.25
Depletion of host Langerhans cells before transplantation of donor alloreactive T cells prevents skin graft-versus-host disease. Nat Med (2004) 3.17
Differential expression of novel potential regulators in hematopoietic stem cells. PLoS Genet (2005) 3.11
An antibody against SSEA-5 glycan on human pluripotent stem cells enables removal of teratoma-forming cells. Nat Biotechnol (2011) 3.05
Germ-layer and lineage-restricted stem/progenitors regenerate the mouse digit tip. Nature (2011) 3.03
Isolation and characterization of a protochordate histocompatibility locus. Nature (2005) 2.96
Human bone marrow hematopoietic stem cells are increased in frequency and myeloid-biased with age. Proc Natl Acad Sci U S A (2011) 2.96
Hematopoietic stem cells are uniquely selective in their migratory response to chemokines. J Exp Med (2002) 2.96
The JAK2 V617F mutation occurs in hematopoietic stem cells in polycythemia vera and predisposes toward erythroid differentiation. Proc Natl Acad Sci U S A (2006) 2.94
Hematopoietic stem and progenitor cells: clinical and preclinical regeneration of the hematolymphoid system. Annu Rev Med (2005) 2.92
Transcriptional and functional profiling of human embryonic stem cell-derived cardiomyocytes. PLoS One (2008) 2.85
Memory T and memory B cells share a transcriptional program of self-renewal with long-term hematopoietic stem cells. Proc Natl Acad Sci U S A (2006) 2.83
Calreticulin is the dominant pro-phagocytic signal on multiple human cancers and is counterbalanced by CD47. Sci Transl Med (2010) 2.79
Dysregulated gene expression networks in human acute myelogenous leukemia stem cells. Proc Natl Acad Sci U S A (2009) 2.76
Efficient transplantation via antibody-based clearance of hematopoietic stem cell niches. Science (2007) 2.69
Extranodal dissemination of non-Hodgkin lymphoma requires CD47 and is inhibited by anti-CD47 antibody therapy. Blood (2011) 2.69
microRNA-29a induces aberrant self-renewal capacity in hematopoietic progenitors, biased myeloid development, and acute myeloid leukemia. J Exp Med (2010) 2.68
Hematopoietic stem cell quiescence is maintained by compound contributions of the retinoblastoma gene family. Cell Stem Cell (2008) 2.67
Ethics. The ISSCR guidelines for human embryonic stem cell research. Science (2007) 2.62
CD47-blocking antibodies restore phagocytosis and prevent atherosclerosis. Nature (2016) 2.53
CX3CR1 is required for monocyte homeostasis and atherogenesis by promoting cell survival. Blood (2008) 2.52
Ly6d marks the earliest stage of B-cell specification and identifies the branchpoint between B-cell and T-cell development. Genes Dev (2009) 2.46
Clonal analysis of mouse development reveals a polyclonal origin for yolk sac blood islands. Dev Cell (2006) 2.45
Hematopoietic stem cell: self-renewal versus differentiation. Wiley Interdiscip Rev Syst Biol Med (2010) 2.38
New evidence supporting megakaryocyte-erythrocyte potential of flk2/flt3+ multipotent hematopoietic progenitors. Cell (2006) 2.34
MLL-GAS7 transforms multipotent hematopoietic progenitors and induces mixed lineage leukemias in mice. Cancer Cell (2003) 2.33
Telomerase is required to slow telomere shortening and extend replicative lifespan of HSCs during serial transplantation. Blood (2003) 2.29
Therapeutic antibody targeting of CD47 eliminates human acute lymphoblastic leukemia. Cancer Res (2010) 2.25
Myeloerythroid-restricted progenitors are sufficient to confer radioprotection and provide the majority of day 8 CFU-S. J Clin Invest (2002) 2.22
Identification of mast cell progenitors in adult mice. Proc Natl Acad Sci U S A (2005) 2.19
Circulation and chemotaxis of fetal hematopoietic stem cells. PLoS Biol (2004) 2.18
Wnt-mediated self-renewal of neural stem/progenitor cells. Proc Natl Acad Sci U S A (2008) 2.15
Epigenetic characterization of hematopoietic stem cell differentiation using miniChIP and bisulfite sequencing analysis. Proc Natl Acad Sci U S A (2007) 2.13
Flk2+ common lymphoid progenitors possess equivalent differentiation potential for the B and T lineages. Blood (2008) 2.06
Gene expression analysis of purified hematopoietic stem cells and committed progenitors. Blood (2003) 2.05
Glycogen synthase kinase 3beta missplicing contributes to leukemia stem cell generation. Proc Natl Acad Sci U S A (2009) 2.02
Isolation of primitive endoderm, mesoderm, vascular endothelial and trophoblast progenitors from human pluripotent stem cells. Nat Biotechnol (2012) 2.00
CD96 is a leukemic stem cell-specific marker in human acute myeloid leukemia. Proc Natl Acad Sci U S A (2007) 1.99
Differential contribution of chemotaxis and substrate restriction to segregation of immature and mature thymocytes. Immunity (2009) 1.96
Gene Expression Commons: an open platform for absolute gene expression profiling. PLoS One (2012) 1.96
Stem cells are units of natural selection in a colonial ascidian. Cell (2005) 1.95
The cancer stem cell hypothesis: a work in progress. Lab Invest (2006) 1.87
The genome sequence of the colonial chordate, Botryllus schlosseri. Elife (2013) 1.86
Reductive isolation from bone marrow and blood implicates common lymphoid progenitors as the major source of thymopoiesis. Blood (2008) 1.86
Antibody therapy targeting the CD47 protein is effective in a model of aggressive metastatic leiomyosarcoma. Proc Natl Acad Sci U S A (2012) 1.86
Hedgehog-responsive candidate cell of origin for diffuse intrinsic pontine glioma. Proc Natl Acad Sci U S A (2011) 1.86
The CD47-SIRPα pathway in cancer immune evasion and potential therapeutic implications. Curr Opin Immunol (2012) 1.84
Leukemic transformation of hematopoietic progenitors by MLL-GAS7 in the absence of Hoxa7 or Hoxa9. Blood (2003) 1.84
Programmed cell removal: a new obstacle in the road to developing cancer. Nat Rev Cancer (2011) 1.84
Cancer stem cell-directed therapies: recent data from the laboratory and clinic. Mol Ther (2008) 1.83
Human neural stem cells induce functional myelination in mice with severe dysmyelination. Sci Transl Med (2012) 1.82
MicroRNA-125b expands hematopoietic stem cells and enriches for the lymphoid-balanced and lymphoid-biased subsets. Proc Natl Acad Sci U S A (2010) 1.82
Pioneer factor interactions and unmethylated CpG dinucleotides mark silent tissue-specific enhancers in embryonic stem cells. Proc Natl Acad Sci U S A (2007) 1.81
In vitro assays misrepresent in vivo lineage potentials of murine lymphoid progenitors. Blood (2010) 1.81
E2A proteins maintain the hematopoietic stem cell pool and promote the maturation of myelolymphoid and myeloerythroid progenitors. Proc Natl Acad Sci U S A (2009) 1.81