Published in J Cell Mol Med on March 28, 2008
Wound repair and regeneration: mechanisms, signaling, and translation. Sci Transl Med (2014) 1.87
Epithelialization in Wound Healing: A Comprehensive Review. Adv Wound Care (New Rochelle) (2014) 1.45
Desmoglein-1/Erbin interaction suppresses ERK activation to support epidermal differentiation. J Clin Invest (2013) 1.11
The skinny on Slug. Mol Carcinog (2010) 1.06
Attenuation of the transforming growth factor beta-signaling pathway in chronic venous ulcers. Mol Med (2010) 1.05
Induction of specific microRNAs inhibits cutaneous wound healing. J Biol Chem (2012) 1.04
Acute and impaired wound healing: pathophysiology and current methods for drug delivery, part 1: normal and chronic wounds: biology, causes, and approaches to care. Adv Skin Wound Care (2012) 0.98
Chronic wound repair and healing in older adults: current status and future research. Wound Repair Regen (2015) 0.97
Clinical challenges of chronic wounds: searching for an optimal animal model to recapitulate their complexity. Dis Model Mech (2014) 0.95
Epidermal Differentiation in Barrier Maintenance and Wound Healing. Adv Wound Care (New Rochelle) (2014) 0.90
Cellular and molecular mechanisms of repair in acute and chronic wound healing. Br J Dermatol (2015) 0.90
Transforming growth factor Beta 3 is required for excisional wound repair in vivo. PLoS One (2012) 0.86
Primary cultured fibroblasts derived from patients with chronic wounds: a methodology to produce human cell lines and test putative growth factor therapy such as GMCSF. J Transl Med (2008) 0.85
Topical Collagen-Based Biomaterials for Chronic Wounds: Rationale and Clinical Application. Adv Wound Care (New Rochelle) (2016) 0.81
Wound edge biopsy sites in chronic wounds heal rapidly and do not result in delayed overall healing of the wounds. Wound Repair Regen (2010) 0.81
Deregulation of epidermal stem cell niche contributes to pathogenesis of nonhealing venous ulcers. Wound Repair Regen (2014) 0.81
Three-dimensional human tissue models that incorporate diabetic foot ulcer-derived fibroblasts mimic in vivo features of chronic wounds. Tissue Eng Part C Methods (2015) 0.81
Identification of a transcriptional signature for the wound healing continuum. Wound Repair Regen (2014) 0.80
Operative debridement of pressure ulcers. World J Surg (2009) 0.80
Chronic wound repair and healing in older adults: current status and future research. J Am Geriatr Soc (2015) 0.79
Comparative Genomic, MicroRNA, and Tissue Analyses Reveal Subtle Differences between Non-Diabetic and Diabetic Foot Skin. PLoS One (2015) 0.77
Palatogenesis and cutaneous repair: A two-headed coin. Dev Dyn (2014) 0.76
Biology and Biomarkers for Wound Healing. Plast Reconstr Surg (2016) 0.76
Utility of a human-mouse xenograft model and in vivo near-infrared fluorescent imaging for studying wound healing. Int Wound J (2013) 0.75
Diabetic wound regeneration using peptide-modified hydrogels to target re-epithelialization. Proc Natl Acad Sci U S A (2016) 0.75
Differential keratin expression during epiboly in a wound model of bioengineered skin and in human chronic wounds. Int J Low Extrem Wounds (2011) 0.75
JMJD3 and NF-κB-dependent activation of Notch1 gene is required for keratinocyte migration during skin wound healing. Sci Rep (2017) 0.75
Cancer cell cycles. Science (1996) 21.29
The retinoblastoma protein and cell cycle control. Cell (1995) 20.21
Asymmetric cell divisions promote stratification and differentiation of mammalian skin. Nature (2005) 6.67
The tight junction: a multifunctional complex. Am J Physiol Cell Physiol (2004) 6.13
Wound healing: an overview of acute, fibrotic and delayed healing. Front Biosci (2004) 5.59
Claudin-based tight junctions are crucial for the mammalian epidermal barrier: a lesson from claudin-1-deficient mice. J Cell Biol (2002) 5.51
Notch signaling is a direct determinant of keratinocyte growth arrest and entry into differentiation. EMBO J (2001) 5.29
Cellular and molecular basis of wound healing in diabetes. J Clin Invest (2007) 4.22
Limb and skin abnormalities in mice lacking IKKalpha. Science (1999) 3.85
Diabetic impairments in NO-mediated endothelial progenitor cell mobilization and homing are reversed by hyperoxia and SDF-1 alpha. J Clin Invest (2007) 3.63
Microarray analysis and tumor classification. N Engl J Med (2006) 3.35
Rapid healing of venous ulcers and lack of clinical rejection with an allogeneic cultured human skin equivalent. Human Skin Equivalent Investigators Group. Arch Dermatol (1998) 3.26
Onset of keratin 17 expression coincides with the definition of major epithelial lineages during skin development. J Cell Biol (1998) 2.91
Chronic venous insufficiency and venous leg ulceration. J Am Acad Dermatol (2001) 2.48
Molecular pathogenesis of chronic wounds: the role of beta-catenin and c-myc in the inhibition of epithelialization and wound healing. Am J Pathol (2005) 2.21
Molecular markers in patients with chronic wounds to guide surgical debridement. Mol Med (2007) 2.06
Genomic analysis defines a cancer-specific gene expression signature for human squamous cell carcinoma and distinguishes malignant hyperproliferation from benign hyperplasia. J Invest Dermatol (2006) 2.01
Gene expression profiling of cutaneous wound healing. J Transl Med (2007) 1.91
Role of aPKC isoforms and their binding partners Par3 and Par6 in epidermal barrier formation. J Invest Dermatol (2006) 1.91
The microarray data analysis process: from raw data to biological significance. NeuroRx (2006) 1.82
Expression of epidermal keratins and filaggrin during human fetal skin development. J Cell Biol (1985) 1.68
Bone morphogenetic proteins and their antagonists in skin and hair follicle biology. J Invest Dermatol (2003) 1.60
eIF4E promotes nuclear export of cyclin D1 mRNAs via an element in the 3'UTR. J Cell Biol (2005) 1.49
Effects of tumor necrosis factor-alpha (TNF alpha) in epidermal keratinocytes revealed using global transcriptional profiling. J Biol Chem (2004) 1.48
Complex redundancy to build a simple epidermal permeability barrier. Curr Opin Cell Biol (2003) 1.46
Epidermal stem cells: the cradle of epidermal determination, differentiation and wound healing. Biol Cell (2005) 1.43
Novel genomic effects of glucocorticoids in epidermal keratinocytes: inhibition of apoptosis, interferon-gamma pathway, and wound healing along with promotion of terminal differentiation. J Biol Chem (2006) 1.43
Suprabasal Dsg2 expression in transgenic mouse skin confers a hyperproliferative and apoptosis-resistant phenotype to keratinocytes. J Cell Sci (2007) 1.39
Protocol for the successful treatment of venous ulcers. Am J Surg (2004) 1.39
Epidermal tight junctions: ZO-1 and occludin are expressed in mature, developing, and affected skin and in vitro differentiating keratinocytes. J Invest Dermatol (2001) 1.37
Direct evidence that involucrin is a major early isopeptide cross-linked component of the keratinocyte cornified cell envelope. J Biol Chem (1997) 1.33
Comparative analysis of gene expression profiles in intact and damaged regions of human osteoarthritic cartilage. Arthritis Rheum (2006) 1.27
Cancers as wounds that do not heal: differences and similarities between renal regeneration/repair and renal cell carcinoma. Cancer Res (2006) 1.26
Suprabasal desmoglein 3 expression in the epidermis of transgenic mice results in hyperproliferation and abnormal differentiation. Mol Cell Biol (2002) 1.25
Venous ulcer: epidemiology, physiopathology, diagnosis and treatment. Int J Dermatol (2005) 1.22
Desmosomal cadherin misexpression alters beta-catenin stability and epidermal differentiation. Mol Cell Biol (2005) 1.21
Epidermal signal transduction and transcription factor activation in activated keratinocytes. J Dermatol Sci (1998) 1.21
Pathway-specific profiling identifies the NF-kappa B-dependent tumor necrosis factor alpha-regulated genes in epidermal keratinocytes. J Biol Chem (2005) 1.21
Angiopoietin-related growth factor (AGF) promotes epidermal proliferation, remodeling, and regeneration. Proc Natl Acad Sci U S A (2003) 1.15
Wound chronicity and fibroblast senescence--implications for treatment. Int Wound J (2005) 1.15
Transcriptional profiling of epidermal differentiation. Physiol Genomics (2006) 1.13
Desmosomes: differentiation, development, dynamics and disease. Curr Opin Cell Biol (1996) 1.13
Early gene expression profile of human skin to injury using high-density cDNA microarrays. Wound Repair Regen (2002) 1.11
Transcriptional profiling of epidermal keratinocytes: comparison of genes expressed in skin, cultured keratinocytes, and reconstituted epidermis, using large DNA microarrays. J Invest Dermatol (2003) 1.08
Striate palmoplantar keratoderma arising from desmoplakin and desmoglein 1 mutations is associated with contrasting perturbations of desmosomes and the keratin filament network. Br J Dermatol (2004) 1.05
Regulation of the Dlx3 homeobox gene upon differentiation of mouse keratinocytes. J Biol Chem (1999) 1.04
IL-6 modulates alpha-smooth muscle actin expression in dermal fibroblasts from IL-6-deficient mice. J Invest Dermatol (2006) 1.03
Regulated expression of human filaggrin in keratinocytes results in cytoskeletal disruption, loss of cell-cell adhesion, and cell cycle arrest. Exp Cell Res (2001) 1.01
Medical costs of treating venous stasis ulcers: evidence from a retrospective cohort study. Vasc Med (1999) 1.01
Regulation of desmocollin gene expression in the epidermis: CCAAT/enhancer-binding proteins modulate early and late events in keratinocyte differentiation. Biochem J (2004) 1.01
Cellular senescence mechanisms in chronic wound healing. Cell Death Differ (2005) 1.00
Guidelines for the treatment of venous ulcers. Wound Repair Regen (2007) 0.97
Unique keratinocyte-specific effects of interferon-gamma that protect skin from viruses, identified using transcriptional profiling. Antivir Ther (2003) 0.97
Differential expression pattern of the three Fringe genes is associated with epidermal differentiation. J Invest Dermatol (1998) 0.96
Venous ulcers. Clin Dermatol (2007) 0.96
Interleukin-1 induces transcription of keratin K6 in human epidermal keratinocytes. J Invest Dermatol (2001) 0.95
Increased keratinocyte proliferation initiated through downregulation of desmoplakin by RNA interference. Exp Cell Res (2007) 0.95
Regulation of epidermal expression of keratin K17 in inflammatory skin diseases. J Invest Dermatol (1996) 0.94
BMP2 and BMP6 control p57(Kip2) expression and cell growth arrest/terminal differentiation in normal primary human epidermal keratinocytes. Cell Signal (2006) 0.93
1,25-dihydroxyvitamin D3 induces phospholipase D-1 expression in primary mouse epidermal keratinocytes. J Biol Chem (1999) 0.92
From description to causality: mechanisms of gene expression signatures in cancer. Cell Cycle (2006) 0.87
Tight junction proteins in the skin. Skin Pharmacol Physiol (2006) 0.87
Possible role of phospholipase D in cellular differentiation and apoptosis. Chem Phys Lipids (1999) 0.86
Sustained phospholipase D activation is associated with keratinocyte differentiation. Carcinogenesis (1999) 0.86
Expression of apoptosis- and cell cycle-related proteins in epidermis of venous leg and diabetic foot ulcers. Surgery (2003) 0.85
Common ground in the transcriptional profiles of wounds and tumors. Genome Biol (2004) 0.83
Ropivacaine and lidocaine inhibit proliferation of non-transformed cultured adult human fibroblasts, endothelial cells and keratinocytes. Agents Actions (1993) 0.83
Patterns of venous reflux and obstruction in patients with skin damage due to chronic venous disease. Vasc Endovascular Surg (2007) 0.82
Gene array technology and pathogenesis of chronic wounds. Am J Surg (2004) 0.80
Tightening the epidermal barrier with atypical PKCs. J Invest Dermatol (2007) 0.80
Keratinocyte junctions and the epidermal barrier: how to make a skin-tight dress. J Cell Biol (2002) 0.76
Growth factors and cytokines in wound healing. Wound Repair Regen (2009) 7.14
Cellular and molecular basis of wound healing in diabetes. J Clin Invest (2007) 4.22
The role of vascular endothelial growth factor in wound healing. J Surg Res (2008) 2.68
Molecular pathogenesis of chronic wounds: the role of beta-catenin and c-myc in the inhibition of epithelialization and wound healing. Am J Pathol (2005) 2.21
Desmoglein 4 in hair follicle differentiation and epidermal adhesion: evidence from inherited hypotrichosis and acquired pemphigus vulgaris. Cell (2003) 2.06
Molecular markers in patients with chronic wounds to guide surgical debridement. Mol Med (2007) 2.06
Mechanism of sustained release of vascular endothelial growth factor in accelerating experimental diabetic healing. J Invest Dermatol (2009) 1.68
High cost of stage IV pressure ulcers. Am J Surg (2010) 1.68
Compound heterozygous desmoplakin mutations result in a phenotype with a combination of myocardial, skin, hair, and enamel abnormalities. J Invest Dermatol (2009) 1.62
Epidermal stem cells: the cradle of epidermal determination, differentiation and wound healing. Biol Cell (2005) 1.43
Novel genomic effects of glucocorticoids in epidermal keratinocytes: inhibition of apoptosis, interferon-gamma pathway, and wound healing along with promotion of terminal differentiation. J Biol Chem (2006) 1.43
Suprabasal Dsg2 expression in transgenic mouse skin confers a hyperproliferative and apoptosis-resistant phenotype to keratinocytes. J Cell Sci (2007) 1.39
Cortisol synthesis in epidermis is induced by IL-1 and tissue injury. J Biol Chem (2011) 1.36
Interactions of methicillin resistant Staphylococcus aureus USA300 and Pseudomonas aeruginosa in polymicrobial wound infection. PLoS One (2013) 1.32
Radiofrequency facial rejuvenation: evidence-based effect. J Am Acad Dermatol (2011) 1.26
The nuclear hormone receptor coactivator NRC is a pleiotropic modulator affecting growth, development, apoptosis, reproduction, and wound repair. Mol Cell Biol (2004) 1.16
Clinical application of growth factors and cytokines in wound healing. Wound Repair Regen (2014) 1.16
Desmoglein 4 is expressed in highly differentiated keratinocytes and trichocytes in human epidermis and hair follicle. Differentiation (2006) 1.14
Adverse effects of dietary glycotoxins on wound healing in genetically diabetic mice. Diabetes (2003) 1.14
A gene signature of nonhealing venous ulcers: potential diagnostic markers. J Am Acad Dermatol (2008) 1.13
Upstream determinants of estrogen receptor-alpha regulation of metastatic tumor antigen 3 pathway. J Biol Chem (2004) 1.12
An adenosine-to-inosine tRNA-editing enzyme that can perform C-to-U deamination of DNA. Proc Natl Acad Sci U S A (2007) 1.10
Transcriptional profiling of epidermal keratinocytes: comparison of genes expressed in skin, cultured keratinocytes, and reconstituted epidermis, using large DNA microarrays. J Invest Dermatol (2003) 1.08
The synergism of age and db/db genotype impairs wound healing. Exp Gerontol (2007) 1.07
Delineation of diversified desmoglein distribution in stratified squamous epithelia: implications in diseases. Exp Dermatol (2006) 1.06
ADAM12: a potential target for the treatment of chronic wounds. J Mol Med (Berl) (2008) 1.06
Attenuation of the transforming growth factor beta-signaling pathway in chronic venous ulcers. Mol Med (2010) 1.05
CRE recombinase-based positive-negative selection systems for genetic manipulation in Trypanosoma brucei. Mol Biochem Parasitol (2007) 1.05
Induction of specific microRNAs inhibits cutaneous wound healing. J Biol Chem (2012) 1.04
Guidelines to aid healing of acute wounds by decreasing impediments of healing. Wound Repair Regen (2009) 1.01
From an enhanceosome to a repressosome: molecular antagonism between glucocorticoids and EGF leads to inhibition of wound healing. J Mol Biol (2004) 1.01
The role of surgical debridement in healing of diabetic foot ulcers. Wound Repair Regen (2010) 0.99
Role of keratinocytes in healing of chronic wounds. Surg Technol Int (2008) 0.99
Prevention and reversal of diabetic nephropathy in db/db mice treated with alagebrium (ALT-711). Am J Nephrol (2006) 0.98
Chronic wound repair and healing in older adults: current status and future research. Wound Repair Regen (2015) 0.97
Healing of elderly patients with diabetic foot ulcers, venous stasis ulcers, and pressure ulcers. Surg Technol Int (2003) 0.96
Guidelines for the prevention of diabetic ulcers. Wound Repair Regen (2008) 0.96
Decreased plakophilin-1 expression promotes increased motility in head and neck squamous cell carcinoma cells. Cell Commun Adhes (2007) 0.95
Using gene transcription patterns (bar coding scans) to guide wound debridement and healing. Adv Skin Wound Care (2008) 0.94
Severe keratin 5 and 14 mutations induce down-regulation of junction proteins in keratinocytes. Exp Cell Res (2009) 0.94
Standardization of wound photography using the Wound Electronic Medical Record. Adv Skin Wound Care (2009) 0.93
Loss of cell adhesion in Dsg3bal-Pas mice with homozygous deletion mutation (2079del14) in the desmoglein 3 gene. J Invest Dermatol (2002) 0.92
Role of Scarf and its binding target proteins in epidermal calcium homeostasis. J Biol Chem (2007) 0.92
Farnesyl pyrophosphate is a novel transcriptional activator for a subset of nuclear hormone receptors. Mol Endocrinol (2007) 0.91
Farnesyl pyrophosphate inhibits epithelialization and wound healing through the glucocorticoid receptor. J Biol Chem (2009) 0.90
Differential structural properties and expression patterns suggest functional significance for multiple mouse desmoglein 1 isoforms. Differentiation (2004) 0.89
Statistical analysis of wound-healing rates for pressure ulcers. Am J Surg (2004) 0.89
Keratin dressings speed epithelialization of deep partial-thickness wounds. Wound Repair Regen (2012) 0.89
US-National Institutes of Health-funded research for cutaneous wounds in 2012. Wound Repair Regen (2013) 0.89
Thyroid hormones and gamma interferon specifically increase K15 keratin gene transcription. Mol Cell Biol (2004) 0.88
Preliminary development of a diabetic foot ulcer database from a wound electronic medical record: a tool to decrease limb amputations. Wound Repair Regen (2009) 0.87
Extracellular matrix in cutaneous ageing: the effects of 0.1% copper-zinc malonate-containing cream on elastin biosynthesis. Exp Dermatol (2009) 0.87
Clinical efficacy and mechanism of bilayered living human skin equivalent (HSE) in treatment of diabetic foot ulcers. Surg Technol Int (2003) 0.86
Mesenchymal stem cell therapy and delivery systems in nonhealing wounds. Adv Skin Wound Care (2011) 0.86
The book of opposites: the role of the nuclear receptor co-regulators in the suppression of epidermal genes by retinoic acid and thyroid hormone receptors. J Invest Dermatol (2005) 0.85
Primary cultured fibroblasts derived from patients with chronic wounds: a methodology to produce human cell lines and test putative growth factor therapy such as GMCSF. J Transl Med (2008) 0.85
Electro-optical Synergy Technique: A New and Effective Nonablative Approach to Skin Aging. J Clin Aesthet Dermatol (2010) 0.85
Pathogenesis and treatment of pain in patients with chronic wounds. Surg Technol Int (2003) 0.84
Dual-specificity phosphatases in the hypo-osmotic stress response of keratin-defective epithelial cell lines. Exp Cell Res (2008) 0.84
Maintenance debridement in the treatment of difficult-to-heal chronic wounds. Recommendations of an expert panel. Ostomy Wound Manage (2008) 0.83
The role of stem cells in the treatment of diabetic foot ulcers. Diabetes Res Clin Pract (2011) 0.83
Operative debridement of diabetic foot ulcers. J Am Coll Surg (2008) 0.83
The role of surgical debridement in healing of diabetic foot ulcers. Skinmed (2012) 0.83
Analysis and meta-analysis of transcriptional profiling in human epidermis. Methods Mol Biol (2014) 0.83
Comprehensive transcriptional profiling of human epidermis, reconstituted epidermal equivalents, and cultured keratinocytes using DNA microarray chips. Methods Mol Biol (2010) 0.82
Deep tissue injury in development of pressure ulcers: a decrease of inflammasome activation and changes in human skin morphology in response to aging and mechanical load. PLoS One (2013) 0.82
C to U editing at position 32 of the anticodon loop precedes tRNA 5' leader removal in trypanosomatids. Nucleic Acids Res (2007) 0.81
Superficial dsg2 expression limits epidermal blister formation mediated by pemphigus foliaceus antibodies and exfoliative toxins. Dermatol Res Pract (2010) 0.81
Three-dimensional human tissue models that incorporate diabetic foot ulcer-derived fibroblasts mimic in vivo features of chronic wounds. Tissue Eng Part C Methods (2015) 0.81
Surgical pathology to describe the clinical margin of debridement of chronic wounds using a wound electronic medical record. J Am Coll Surg (2009) 0.81
Human ex vivo wound healing model. Methods Mol Biol (2013) 0.80
A coordinated approach to cutaneous wound healing: vibrational microscopy and molecular biology. J Cell Mol Med (2008) 0.80