Translating insights from the cancer genome into clinical practice.

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Published in Nature on April 03, 2008

Authors

Lynda Chin1, Joe W Gray

Author Affiliations

1: Dana-Farber Cancer Institute and Harvard Medical School, 44 Binney Street, Boston, Massachusetts 02115, USA. lynda_chin@dfci.harvard.edu

Associated clinical trials:

Molecular Profiling of Colorectal Cancer | NCT04863768

Melanoma: Genomic Profiles, Molecular Markers and Therapeutic Implications | NCT05119829

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Multiple roles of the candidate oncogene ZNF217 in ovarian epithelial neoplastic progression. Int J Cancer (2007) 1.10

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Rab25 increases cellular ATP and glycogen stores protecting cancer cells from bioenergetic stress. EMBO Mol Med (2012) 1.03

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Lectin chromatography/mass spectrometry discovery workflow identifies putative biomarkers of aggressive breast cancers. J Proteome Res (2012) 1.01

A primer on regression methods for decoding cis-regulatory logic. PLoS Comput Biol (2009) 1.00

Genetic differences in transcript responses to low-dose ionizing radiation identify tissue functions associated with breast cancer susceptibility. PLoS One (2012) 1.00

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Integrating biological knowledge into variable selection: an empirical Bayes approach with an application in cancer biology. BMC Bioinformatics (2012) 0.98