Published in Proc Natl Acad Sci U S A on April 30, 2008
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Energy barriers, pathways, and dynamics during folding of large, multidomain RNAs. Curr Opin Chem Biol (2008) 1.15
Crystal structure of 3WJ core revealing divalent ion-promoted thermostability and assembly of the Phi29 hexameric motor pRNA. RNA (2013) 1.14
Salt-dependent folding energy landscape of RNA three-way junction. Biophys J (2010) 0.93
Comparisons between chemical mapping and binding to isoenergetic oligonucleotide microarrays reveal unexpected patterns of binding to the Bacillus subtilis RNase P RNA specificity domain. Biochemistry (2010) 0.92
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Exploring the electrostatic energy landscape for tetraloop-receptor docking. Phys Chem Chem Phys (2013) 0.79
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Single-molecule enzymology of RNA: essential functional groups impact catalysis from a distance. Proc Natl Acad Sci U S A (2004) 2.11
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Single-molecule RNA science. Annu Rev Biophys Biomol Struct (2005) 1.93
Observation of a power-law memory kernel for fluctuations within a single protein molecule. Phys Rev Lett (2005) 1.91
Distinguishing between two-state and three-state models for ubiquitin folding. Biochemistry (2000) 1.71
Observing spontaneous branch migration of Holliday junctions one step at a time. Proc Natl Acad Sci U S A (2005) 1.60
Observation of internal cleavage and ligation reactions of a ribozyme. Nat Struct Mol Biol (2004) 1.58
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The rate-limiting step in the folding of a large ribozyme without kinetic traps. Proc Natl Acad Sci U S A (2002) 1.30
The thermodynamic origin of the stability of a thermophilic ribozyme. Proc Natl Acad Sci U S A (2001) 1.30
Metal ion dependence, thermodynamics, and kinetics for intramolecular docking of a GAAA tetraloop and receptor connected by a flexible linker. Biochemistry (2006) 1.15
Evidence for non-two-state kinetics in the nucleocapsid protein chaperoned opening of DNA hairpins. J Phys Chem B (2006) 1.14
Efficient fluorescence labeling of a large RNA through oligonucleotide hybridization. RNA (2004) 0.99
Folding of a universal ribozyme: the ribonuclease P RNA. Q Rev Biophys (2007) 0.98
A large collapsed-state RNA can exhibit simple exponential single-molecule dynamics. J Mol Biol (2008) 0.89
Stepwise conversion of a mesophilic to a thermophilic ribozyme. J Mol Biol (2003) 0.85
Measurement of stochastic entropy production. Phys Rev Lett (2006) 0.81
Kramers model with a power-law friction kernel: dispersed kinetics and dynamic disorder of biochemical reactions. Phys Rev E Stat Nonlin Soft Matter Phys (2006) 0.79
Nanometer-localized multiple single-molecule fluorescence microscopy. Proc Natl Acad Sci U S A (2004) 5.98
N6-methyladenosine in nuclear RNA is a major substrate of the obesity-associated FTO. Nat Chem Biol (2011) 5.96
Single-molecule mechanics of mussel adhesion. Proc Natl Acad Sci U S A (2006) 5.71
An evolutionarily conserved mechanism for controlling the efficiency of protein translation. Cell (2010) 4.45
Random-coil behavior and the dimensions of chemically unfolded proteins. Proc Natl Acad Sci U S A (2004) 4.44
Ever-fluctuating single enzyme molecules: Michaelis-Menten equation revisited. Nat Chem Biol (2005) 4.24
Tissue-specific differences in human transfer RNA expression. PLoS Genet (2006) 4.10
Codon-usage-based inhibition of HIV protein synthesis by human schlafen 11. Nature (2012) 2.98
Lowering the temperature of solid oxide fuel cells. Science (2011) 2.75
Basis for structural diversity in homologous RNAs. Science (2004) 2.70
Crystal structure of the specificity domain of ribonuclease P. Nature (2003) 2.69
Light-activated DNA binding in a designed allosteric protein. Proc Natl Acad Sci U S A (2008) 2.67
TULIPs: tunable, light-controlled interacting protein tags for cell biology. Nat Methods (2012) 2.59
Innate immune and chemically triggered oxidative stress modifies translational fidelity. Nature (2009) 2.50
Selective charging of tRNA isoacceptors induced by amino-acid starvation. EMBO Rep (2005) 2.48
Structure of a bacterial ribonuclease P holoenzyme in complex with tRNA. Nature (2010) 2.40
Statistical coil model of the unfolded state: resolving the reconciliation problem. Proc Natl Acad Sci U S A (2005) 2.32
Leucine-tRNA initiates at CUG start codons for protein synthesis and presentation by MHC class I. Science (2012) 2.30
Crystal structure of the RNA component of bacterial ribonuclease P. Nature (2005) 2.10
tRNA over-expression in breast cancer and functional consequences. Nucleic Acids Res (2009) 2.08
Outcome of a workshop on applications of protein models in biomedical research. Structure (2009) 2.05
Diversity of tRNA genes in eukaryotes. Nucleic Acids Res (2006) 2.05
Investigations into sequence and conformational dependence of backbone entropy, inter-basin dynamics and the Flory isolated-pair hypothesis for peptides. J Mol Biol (2003) 2.00
Science education. Educating future scientists. Science (2003) 1.97
Protein folding: defining a "standard" set of experimental conditions and a preliminary kinetic data set of two-state proteins. Protein Sci (2005) 1.91
Exploring the regulation of tRNA distribution on the genomic scale. J Mol Biol (2004) 1.80
The AlkB domain of mammalian ABH8 catalyzes hydroxylation of 5-methoxycarbonylmethyluridine at the wobble position of tRNA. Angew Chem Int Ed Engl (2010) 1.76
Helix, sheet, and polyproline II frequencies and strong nearest neighbor effects in a restricted coil library. Biochemistry (2005) 1.73
Rationally improving LOV domain-based photoswitches. Nat Methods (2010) 1.72
Fast and slow intermediate accumulation and the initial barrier mechanism in protein folding. J Mol Biol (2002) 1.70
Single-molecule studies highlight conformational heterogeneity in the early folding steps of a large ribozyme. Proc Natl Acad Sci U S A (2004) 1.69
Identification of recognition residues for ligation-based detection and quantitation of pseudouridine and N6-methyladenosine. Nucleic Acids Res (2007) 1.66
Genome-wide analysis of tRNA charging and activation of the eIF2 kinase Gcn2p. J Biol Chem (2009) 1.64
Discerning the structure and energy of multiple transition states in protein folding using psi-analysis. J Mol Biol (2004) 1.61
A role for tRNA modifications in genome structure and codon usage. Cell (2012) 1.57
Real-time RNA profiling within a single bacterium. Proc Natl Acad Sci U S A (2005) 1.56
RNA folding: models and perspectives. Curr Opin Struct Biol (2003) 1.56
Intercellular transfer of the cellular prion protein. J Biol Chem (2002) 1.54
Genome-wide identification and quantitative analysis of cleaved tRNA fragments induced by cellular stress. J Biol Chem (2012) 1.47
Early collapse is not an obligate step in protein folding. J Mol Biol (2004) 1.45
Ultrafast dynamics of polarons in conductive polyaniline: comparison of primary and secondary doped forms. J Phys Chem B (2008) 1.37
Probing N6-methyladenosine RNA modification status at single nucleotide resolution in mRNA and long noncoding RNA. RNA (2013) 1.37
Folding of noncoding RNAs during transcription facilitated by pausing-induced nonnative structures. Proc Natl Acad Sci U S A (2007) 1.36
Genome-wide analysis of N1-methyl-adenosine modification in human tRNAs. RNA (2010) 1.33
A multicenter application and evaluation of the oxford classification of IgA nephropathy in adult chinese patients. Am J Kidney Dis (2012) 1.32
Structure of a folding intermediate reveals the interplay between core and peripheral elements in RNA folding. J Mol Biol (2005) 1.31
Cellular dynamics of RNA modification. Acc Chem Res (2011) 1.28
Mimicking the folding pathway to improve homology-free protein structure prediction. Proc Natl Acad Sci U S A (2009) 1.25
High levels of tRNA abundance and alteration of tRNA charging by bortezomib in multiple myeloma. Biochem Biophys Res Commun (2009) 1.23
A self-defeating anabolic program leads to β-cell apoptosis in endoplasmic reticulum stress-induced diabetes via regulation of amino acid flux. J Biol Chem (2013) 1.22
Integration of general amino acid control and target of rapamycin (TOR) regulatory pathways in nitrogen assimilation in yeast. J Biol Chem (2010) 1.20
Understanding protein hydrogen bond formation with kinetic H/D amide isotope effects. Nat Struct Biol (2002) 1.20
Minimalist representations and the importance of nearest neighbor effects in protein folding simulations. J Mol Biol (2006) 1.19
Analysis of RNA base modification and structural rearrangement by single-molecule real-time detection of reverse transcription. J Nanobiotechnology (2013) 1.19
Phase-changing sacrificial materials for solvent bonding of high-performance polymeric capillary electrophoresis microchips. Anal Chem (2005) 1.19
High-resolution N(6) -methyladenosine (m(6) A) map using photo-crosslinking-assisted m(6) A sequencing. Angew Chem Int Ed Engl (2014) 1.18
N6-methyladenosine–encoded epitranscriptomics. Nat Struct Mol Biol (2016) 1.17
Structure of ribonuclease P--a universal ribozyme. Curr Opin Struct Biol (2006) 1.16
Intracellular transport of insulin granules is a subordinated random walk. Proc Natl Acad Sci U S A (2013) 1.16
Automated real-space refinement of protein structures using a realistic backbone move set. Biophys J (2011) 1.16
Profiling non-lysyl tRNAs in HIV-1. RNA (2009) 1.14
Functional analysis of human tRNA isodecoders. J Mol Biol (2009) 1.13
Dynamics of hydrogen bond desolvation in protein folding. J Mol Biol (2002) 1.13
Stochastic scanning multiphoton multifocal microscopy. Opt Express (2006) 1.12
The amino-terminal helix modulates light-activated conformational changes in AsLOV2. J Mol Biol (2012) 1.12
Theranostic probe based on lanthanide-doped nanoparticles for simultaneous in vivo dual-modal imaging and photodynamic therapy. Adv Mater (2012) 1.11
Modeling the hydration layer around proteins: applications to small- and wide-angle x-ray scattering. Biophys J (2011) 1.11
A systematic, ligation-based approach to study RNA modifications. RNA (2006) 1.10
Reduced C(beta) statistical potentials can outperform all-atom potentials in decoy identification. Protein Sci (2007) 1.09
Modeling the hydration layer around proteins: HyPred. Biophys J (2010) 1.08
Misacylation of tRNA with methionine in Saccharomyces cerevisiae. Nucleic Acids Res (2012) 1.08
Fully reduced ribonuclease A does not expand at high denaturant concentration or temperature. J Mol Biol (2007) 1.08
Intrinsic lifetimes of the excited state of DNA and RNA bases. J Am Chem Soc (2002) 1.07
Large-scale context in protein folding: villin headpiece. Biochemistry (2003) 1.07
Transcriptional pausing coordinates folding of the aptamer domain and the expression platform of a riboswitch. Proc Natl Acad Sci U S A (2012) 1.07
Misacylation of specific nonmethionyl tRNAs by a bacterial methionyl-tRNA synthetase. Proc Natl Acad Sci U S A (2011) 1.07
Syntheses of two 5-hydroxymethyl-2'-deoxycytidine phosphoramidites with TBDMS as the 5-hydroxymethyl protecting group and their incorporation into DNA. J Org Chem (2011) 1.07
Evidence for a diffusion-controlled mechanism for fluorescence blinking of colloidal quantum dots. Proc Natl Acad Sci U S A (2007) 1.06
On the precision of experimentally determined protein folding rates and phi-values. Protein Sci (2006) 1.06
Protein vivisection reveals elusive intermediates in folding. J Mol Biol (2010) 1.06
Quantifying the structural requirements of the folding transition state of protein A and other systems. J Mol Biol (2008) 1.05
Reversible and rapid transfer-RNA deactivation as a mechanism of translational repression in stress. PLoS Genet (2013) 1.05
Affinity monolith-integrated poly(methyl methacrylate) microchips for on-line protein extraction and capillary electrophoresis. Anal Chem (2008) 1.04
Propagation lengths and group velocities of plasmons in chemically synthesized gold and silver nanowires. ACS Nano (2012) 1.04
Small proteins fold through transition states with native-like topologies. J Mol Biol (2006) 1.04
Folding of a large protein at high structural resolution. Proc Natl Acad Sci U S A (2013) 1.02
A study of the lengthening and contractility of the surgical margins in digestive tract cancer. Am J Surg (2004) 1.01
Prion protein is ubiquitinated after developing protease resistance in the brains of scrapie-infected mice. J Pathol (2004) 1.01
Intramolecular cross-linking evaluated as a structural probe of the protein folding transition state. Biochemistry (2007) 1.00
Barrier-limited, microsecond folding of a stable protein measured with hydrogen exchange: Implications for downhill folding. Proc Natl Acad Sci U S A (2004) 1.00
Fast folding of a helical protein initiated by the collision of unstructured chains. Proc Natl Acad Sci U S A (2004) 1.00
Efficient fluorescence labeling of a large RNA through oligonucleotide hybridization. RNA (2004) 0.99