Published in Nature on February 07, 1991
Successful transmission of a retrovirus depends on the commensal microbiota. Science (2011) 3.34
Identification of human endogenous retroviruses with complex mRNA expression and particle formation. Proc Natl Acad Sci U S A (1993) 2.43
Molecular identification of a novel retrovirus repeatedly isolated from patients with multiple sclerosis. The Collaborative Research Group on Multiple Sclerosis. Proc Natl Acad Sci U S A (1997) 1.97
Coexpression of exogenous and endogenous mouse mammary tumor virus RNA in vivo results in viral recombination and broadens the virus host range. J Virol (1994) 1.57
B cells are essential for murine mammary tumor virus transmission, but not for presentation of endogenous superantigens. J Exp Med (1994) 1.56
Identification of HLA-DR1 beta chain residues critical for binding staphylococcal enterotoxins A and E. J Exp Med (1992) 1.52
An exogenous mouse mammary tumor virus with properties of Mls-1a (Mtv-7). J Exp Med (1992) 1.45
Mls-1 is encoded by the long terminal repeat open reading frame of the mouse mammary tumor provirus Mtv-7. Proc Natl Acad Sci U S A (1992) 1.37
Unique resistance of I/LnJ mice to a retrovirus is due to sustained interferon gamma-dependent production of virus-neutralizing antibodies. J Exp Med (2003) 1.34
Endogenous superantigen expression is controlled by mouse mammary tumor proviral loci. J Exp Med (1991) 1.34
A gammaherpesvirus-secreted activator of Vbeta4+ CD8+ T cells regulates chronic infection and immunopathology. J Exp Med (2008) 1.31
The open reading frames in the 3' long terminal repeats of several mouse mammary tumor virus integrants encode V beta 3-specific superantigens. J Exp Med (1992) 1.30
Retroviral infection of neonatal Peyer's patch lymphocytes: the mouse mammary tumor virus model. J Exp Med (1994) 1.28
Generation of a tumorigenic milk-borne mouse mammary tumor virus by recombination between endogenous and exogenous viruses. J Virol (1997) 1.27
The mouse mammary tumour virus long terminal repeat encodes a type II transmembrane glycoprotein. EMBO J (1992) 1.25
Structural analysis of a mouse mammary tumor virus superantigen. J Exp Med (1992) 1.24
The effects of chronic infection with a superantigen-producing virus. J Exp Med (1992) 1.24
Monoclonal antibody-targeted superantigens: a different class of anti-tumor agents. Proc Natl Acad Sci U S A (1991) 1.22
Human T cells respond to mouse mammary tumor virus-encoded superantigen: V beta restriction and conserved evolutionary features. J Exp Med (1993) 1.21
Immune recognition. Mls: makes a little sense. Nature (1991) 1.17
Genomically imposed and somatically modified human thymocyte V beta gene repertoires. Proc Natl Acad Sci U S A (1991) 1.15
Analysis of the interaction site for the self superantigen Mls-1a on T cell receptor V beta. J Exp Med (1991) 1.13
The use of mammary tumor virus (Mtv)-negative and single-Mtv mice to evaluate the effects of endogenous viral superantigens on the T cell repertoire. J Exp Med (1995) 1.13
Direct evidence for the role of COOH terminus of mouse mammary tumor virus superantigen in determining T cell receptor V beta specificity. J Exp Med (1993) 1.12
A method for production of antibodies to human T-cell receptor beta-chain variable regions. Proc Natl Acad Sci U S A (1991) 1.11
Analysis of the T-cell receptor beta-chain variable-region (V beta) repertoire in monozygotic twins discordant for human immunodeficiency virus: evidence for perturbations of specific V beta segments in CD4+ T cells of the virus-positive twins. Proc Natl Acad Sci U S A (1994) 1.07
Mutational and functional analysis of the C-terminal region of the C3H mouse mammary tumor virus superantigen. J Virol (1998) 1.03
An activation-dependent, T-lymphocyte-specific transcriptional activator in the mouse mammary tumor virus env gene. Mol Cell Biol (1992) 1.02
Factors controlling the expression of mouse mammary tumour virus. Biochem J (1992) 1.02
Expression of human endogenous retrovirus type K envelope glycoprotein in insect and mammalian cells. J Virol (1997) 1.01
Detection and characterization of a glycoprotein encoded by the mouse mammary tumor virus long terminal repeat gene. J Virol (1991) 1.00
Expression of a MHC class II transgene determines both superantigenicity and susceptibility to mammary tumor virus infection. J Exp Med (1993) 0.99
Regulated expression of mouse mammary tumor proviral genes in cells of the B lineage. J Exp Med (1991) 0.98
Identification of diverse full-length endogenous betaretroviruses in megabats and microbats. Retrovirology (2013) 0.96
Epstein-Barr virus latent membrane protein LMP-2A is sufficient for transactivation of the human endogenous retrovirus HERV-K18 superantigen. J Virol (2004) 0.96
In a small multideterminant peptide, each determinant is recognized by a different V beta gene segment. J Exp Med (1992) 0.95
Increased levels of serum IgM antibody to staphylococcal enterotoxin B in patients with rheumatoid arthritis. Ann Rheum Dis (1995) 0.94
Divergent viral superantigens delete V beta 5+ T lymphocytes. Proc Natl Acad Sci U S A (1992) 0.93
Transplacental transmission of a leukemogenic murine leukemia virus. J Virol (1993) 0.92
Binding sites for bacterial and endogenous retroviral superantigens can be dissociated on major histocompatibility complex class II molecules. J Exp Med (1994) 0.91
Transplantation tolerance is unrelated to superantigen-dependent deletion and anergy. Proc Natl Acad Sci U S A (1992) 0.91
Mls-1-like superantigen in the MA/MyJ mouse is encoded by a new mammary tumor provirus that is distinct from Mtv-7. J Exp Med (1992) 0.91
Beta cell expression of endogenous xenotropic retrovirus distinguishes diabetes-susceptible NOD/Lt from resistant NON/Lt mice. J Clin Invest (1992) 0.90
In vivo effects of a recombinant vaccinia virus expressing a mouse mammary tumor virus superantigen. J Virol (1996) 0.90
Virus-encoded superantigens. Microbiol Rev (1996) 0.89
Synovial cells are potent antigen-presenting cells for superantigen, staphylococcal enterotoxin B (SEB). Clin Exp Immunol (1995) 0.89
Reduction of lupus nephritis in MRL/lpr mice by a bacterial superantigen treatment. J Exp Med (1991) 0.89
Endogenous mouse mammary tumor viruses (mtv): new roles for an old virus in cancer, infection, and immunity. Front Oncol (2013) 0.88
Replication of beta- and gammaretroviruses is restricted in I/LnJ mice via the same genetic mechanism. J Virol (2007) 0.88
Mouse mammary tumor virus superantigen expression in B cells is regulated by a central enhancer within the pol gene. J Virol (1998) 0.87
Dual role of commensal bacteria in viral infections. Immunol Rev (2013) 0.87
A novel mechanism of resistance to mouse mammary tumor virus infection. J Virol (2000) 0.87
Shared promoter elements between a viral superantigen and the major histocompatibility complex class II-associated invariant chain. J Virol (1997) 0.85
V beta 17 T-cell deletion by endogenous mammary tumor virus in wild-type-derived mouse strain. Proc Natl Acad Sci U S A (1992) 0.85
Neonatal deletion and selective expansion of mouse T cells by exposure to rabies virus nucleocapsid superantigen. J Exp Med (1994) 0.85
Production and characterization of an Mls-1-specific monoclonal antibody. J Exp Med (1993) 0.85
C3H mouse mammary tumor virus superantigen function requires a splice donor site in the envelope gene. J Virol (2000) 0.85
Acquired Mls-1a-like clonal deletion in Mls-1b mice. J Exp Med (1992) 0.84
The human T cell antigen receptor repertoire: skewed use of V beta gene families by CD8+ T cells. Clin Exp Immunol (1994) 0.83
Role of dendritic cells in the immune response induced by mouse mammary tumor virus superantigen. J Virol (1999) 0.83
Bacterial and viral superantigens: roles in autoimmunity? Ann Rheum Dis (1993) 0.83
Gradual elimination of retroviruses in YBR/Ei mice. J Virol (2006) 0.83
Expression of mouse mammary tumor virus superantigen mRNA in the thymus correlates with kinetics of self-reactive T-cell loss. J Virol (1999) 0.83
Radiation leukemia virus-induced thymic lymphomas express a restricted repertoire of T-cell receptor V beta gene products. J Virol (1994) 0.82
Cross-packaging of genetically distinct mouse and primate retroviral RNAs. Retrovirology (2009) 0.82
Short-term administration of anti-L3T4 MoAb prevents diabetes in NOD mice. Clin Exp Immunol (1993) 0.81
Mouse chromosome 1. Mamm Genome (1992) 0.81
Identification of a limited T-cell receptor beta chain variable region repertoire associated with diabetes in the BB rat. Proc Natl Acad Sci U S A (1991) 0.80
Complete Nucleotide Sequence of Mouse Mammary Tumor Virus from JYG Chinese Wild Mice: Absence of Bacterial Insertion Sequences in the Cloned Viral gag Gene. Breast Cancer (1994) 0.79
Mammalian Lipopolysaccharide Receptors Incorporated into the Retroviral Envelope Augment Virus Transmission. Cell Host Microbe (2015) 0.79
Sequences within the gag gene of mouse mammary tumor virus needed for mammary gland cell transformation. J Virol (2006) 0.79
RIII/Sa mice with a high incidence of mammary tumors express two exogenous strains and one potential endogenous strain of mouse mammary tumor virus. J Virol (2004) 0.78
Does a retrovirally encoded superantigen cause multiple sclerosis? J Neurol Neurosurg Psychiatry (1991) 0.77
Vital role for CD8+ cells in controlling retroviral infections. J Virol (2011) 0.77
Endogenous Mtv-encoded superantigens are not required for development of murine AIDS. J Virol (1996) 0.76
Expression of mouse mammary tumor virus superantigen accelerates tumorigenicity of myeloma cells. J Virol (2000) 0.75
Both H-2- and non-H-2-linked genes influence influenza nucleoprotein epitope recognition by CD4+ T cells. Immunology (1996) 0.75
Lessons Learned from Mouse Mammary Tumor Virus in Animal Models. ILAR J (2016) 0.75
Detection of human endogenous retrovirus type K-specific transcripts in testicular parenchyma and testicular germ cell tumors of adolescents and adults: clinical and biological implications. Am J Pathol (1998) 0.75
The staphylococcal enterotoxins and their relatives. Science (1990) 11.99
The major histocompatibility complex-restricted antigen receptor on T cells. I. Isolation with a monoclonal antibody. J Exp Med (1983) 7.55
Interaction of Staphylococcus aureus toxin "superantigens" with human T cells. Proc Natl Acad Sci U S A (1989) 7.48
Antigen recognition by H-2-restricted T cells. I. Cell-free antigen processing. J Exp Med (1983) 6.97
Control of homeostasis of CD8+ memory T cells by opposing cytokines. Science (2000) 6.22
The antigen-specific, major histocompatibility complex-restricted receptor on T cells. VI. An antibody to a receptor allotype. J Exp Med (1984) 4.29
T cells compete for access to antigen-bearing antigen-presenting cells. J Exp Med (2000) 4.16
Detection of antigen-specific T cells with multivalent soluble class II MHC covalent peptide complexes. Immunity (1998) 4.15
Interleukin-induced increase in Ia expression by normal mouse B cells. J Exp Med (1984) 4.14
A T cell receptor V beta segment that imparts reactivity to a class II major histocompatibility complex product. Cell (1987) 4.09
The T cell receptor. Science (1987) 4.00
Type I interferons keep activated T cells alive. J Exp Med (1999) 3.98
Superantigens and their potential role in human disease. Adv Immunol (1993) 3.88
The role of the T cell receptor in positive and negative selection of developing T cells. Science (1990) 3.64
The major histocompatibility complex-restricted antigen receptor on T cells. II. Role of the L3T4 product. J Exp Med (1983) 3.54
Antigen presentation by Ia+ B cell hybridomas to H-2-restricted T cell hybridomas. Proc Natl Acad Sci U S A (1982) 3.41
The toxicity of staphylococcal enterotoxin B in mice is mediated by T cells. J Exp Med (1990) 3.31
Superantigens interact with MHC class II molecules outside of the antigen groove. Cell (1990) 3.20
An inverse relationship between T cell receptor affinity and antigen dose during CD4(+) T cell responses in vivo and in vitro. Proc Natl Acad Sci U S A (1999) 3.15
Autoimmune disease: why and where it occurs. Nat Med (2001) 3.04
The repertoire of T cells shaped by a single MHC/peptide ligand. Cell (1996) 3.04
Concanavalin A-inducible, interleukin-2-producing T cell hybridoma. J Exp Med (1980) 3.02
Production of soluble MHC class II proteins with covalently bound single peptides. Nature (1994) 2.98
Primary structure of human T-cell receptor alpha-chain. Nature (1985) 2.93
Functional interaction between human T-cell protein CD4 and the major histocompatibility complex HLA-DR antigen. Nature (1987) 2.89
Reactive oxygen species regulate activation-induced T cell apoptosis. Immunity (1999) 2.84
Two better cell lines for making hybridomas expressing specific T cell receptors. J Immunol (1989) 2.78
Immunological adjuvants promote activated T cell survival via induction of Bcl-3. Nat Immunol (2001) 2.76
Cytokine-induced survival of activated T cells in vitro and in vivo. Proc Natl Acad Sci U S A (1998) 2.71
Selective expansion of T cells expressing V beta 2 in toxic shock syndrome. J Exp Med (1990) 2.71
Molecular basis of different forms of metachromatic leukodystrophy. N Engl J Med (1991) 2.69
The major histocompatibility complex-restricted antigen receptor on T cells: distribution on thymus and peripheral T cells. Cell (1984) 2.64
Residues of the variable region of the T-cell-receptor beta-chain that interact with S. aureus toxin superantigens. Nature (1990) 2.60
The mouse T cell receptor: comparison of MHC-restricted receptors on two T cell hybridomas. Cell (1983) 2.58
Structures of an MHC class II molecule with covalently bound single peptides. Science (1996) 2.58
Evidence for two distinct classes of murine B cell growth factors with activities in different functional assays. J Exp Med (1983) 2.56
The effect of thymus environment on T cell development and tolerance. Cell (1988) 2.45
HLA-DR alleles differ in their ability to present staphylococcal enterotoxins to T cells. J Exp Med (1990) 2.30
Homeostasis of alpha beta TCR+ T cells. Nat Immunol (2000) 2.29
Antigen-specific. I region-restricted interactions in vitro between tumor cell lines and T cell hybridomas. J Immunol (1982) 2.26
T cells can distinguish between allogeneic major histocompatibility complex products on different cell types. Nature (1988) 2.21
Use of I region-restricted, antigen-specific T cell hybridomas to produce idiotypically specific anti-receptor antibodies. J Immunol (1983) 2.19
Interleukin 4 (IL-4) or IL-7 prevents the death of resting T cells: stat6 is probably not required for the effect of IL-4. J Exp Med (1997) 2.15
The role of L3T4 in recognition of Ia by a cytotoxic, H-2Dd-specific T cell hybridoma. J Exp Med (1984) 2.13
Rearrangement of T-cell receptor beta-chain genes during T-cell development. Proc Natl Acad Sci U S A (1985) 2.13
Gene transfer of H-2 class II genes: antigen presentation by mouse fibroblast and hamster B-cell lines. Cell (1984) 2.12
Compartmentalization of MHC class II gene expression in transgenic mice. Cell (1988) 2.08
CD4+ T cell division in irradiated mice requires peptides distinct from those responsible for thymic selection. J Exp Med (1999) 2.04
The major histocompatibility complex-restricted antigen receptor on T cells in mouse and man: identification of constant and variable peptides. Cell (1983) 2.04
The major histocompatibility complex-restricted antigen receptor on T cells. IV. An antiidiotypic antibody predicts both antigen and I-specificity. J Exp Med (1983) 2.03
The T cell receptor: the alpha and beta chains define idiotype, and antigen and MHC specificity. Cell (1985) 1.96
Characterization of the two heavy chains of the T3 complex on the surface of human T lymphocytes. J Biol Chem (1984) 1.93
Activation changes the spectrum but not the diversity of genes expressed by T cells. Proc Natl Acad Sci U S A (1999) 1.84
The antigen-specific, major histocompatibility complex-restricted receptor on T cells. Adv Immunol (1986) 1.73
Characterization of the gamma-interferon-mediated induction of antigen-presenting ability in P388D1 cells. J Immunol (1983) 1.69
Direct enumeration of Borrelia-reactive CD4 T cells ex vivo by using MHC class II tetramers. Proc Natl Acad Sci U S A (2000) 1.61
Profound deletion of mature T cells in vivo by chronic exposure to exogenous superantigen. J Immunol (1993) 1.58
Expression of antigen-specific, major histocompatibility complex-restricted receptors by cortical and medullary thymocytes in situ. Cell (1985) 1.57
B cell helper factors. II. Synergy among three helper factors in the response of T cell- and macrophage-depleted B cells. J Immunol (1982) 1.57
The T-cell repertoire for antigen and MHC. Immunol Today (1988) 1.55
The T cell repertoire may be biased in favor of MHC recognition. Cell (1986) 1.55
Subversion of the immune system by pathogens. Cell (1994) 1.53
Structural and functional consequences of altering a peptide MHC anchor residue. J Immunol (2001) 1.51
The staphylococcal enterotoxins and their relatives. Science (1990) 1.50
Use of soluble peptide-DR4 tetramers to detect synovial T cells specific for cartilage antigens in patients with rheumatoid arthritis. Proc Natl Acad Sci U S A (2000) 1.46
Bystander virus infection prolongs activated T cell survival. J Immunol (1999) 1.43
Multiple binding sites for bacterial superantigens on soluble class II MHC molecules. Immunity (1995) 1.41
Peptide sequences of T-cell receptor delta and gamma chains are identical to predicted X and gamma proteins. Nature (1988) 1.41
T-cell survival. Immunol Rev (1998) 1.35
Influence of the major histocompatibility complex on positive thymic selection of V beta 17a+ T cells. Science (1989) 1.34
Crystal structure of mouse H2-M. Immunity (1998) 1.34
The growth of the very large CD8+ T cell clones in older mice is controlled by cytokines. J Immunol (2001) 1.33
Rearrangement of IgH genes in normal thymocyte development. J Immunol (1988) 1.32
TCR-induced transmembrane signaling by peptide/MHC class II via associated Ig-alpha/beta dimers. Science (2001) 1.31
T cell receptor (TCR)-mediated repertoire selection and loss of TCR vbeta diversity during the initiation of a CD4(+) T cell response in vivo. J Exp Med (2000) 1.30
The open reading frames in the 3' long terminal repeats of several mouse mammary tumor virus integrants encode V beta 3-specific superantigens. J Exp Med (1992) 1.30
The effects of chronic infection with a superantigen-producing virus. J Exp Med (1992) 1.24
The major histocompatibility complex-restricted antigen receptor on T cells: the genetics of expression of an allotype. J Immunol (1985) 1.24
T cells can be activated by peptides that are unrelated in sequence to their selecting peptide. Immunity (1997) 1.24
Analysis of V beta 17a expression in new mouse strains bearing the V beta a haplotype. J Exp Med (1989) 1.23
A requirement for nonspecific T cell factors in antibody responses to "T cell independent" antigens. J Immunol (1983) 1.22
CD40 stimulation accelerates deletion of tumor-specific CD8(+) T cells in the absence of tumor-antigen vaccination. Proc Natl Acad Sci U S A (2001) 1.22
CD8+ T-cell clones in old mice. Immunol Rev (1997) 1.21
Positive selection of thymocytes bearing alpha beta T cell receptors. Curr Opin Immunol (1997) 1.20
Nonspecific factors in B cell responses. Immunol Rev (1982) 1.14
Surprisingly uneven distribution of the T cell receptor V beta repertoire in wild mice. J Exp Med (1990) 1.14
Use of somatic cell genetics to study chromosomes contributing to antigen plus I recognition by T cell hybridomas. J Exp Med (1983) 1.14
The major histocompatibility complex-restricted antigen receptor on T cells. Annu Rev Immunol (1984) 1.13
The use of mammary tumor virus (Mtv)-negative and single-Mtv mice to evaluate the effects of endogenous viral superantigens on the T cell repertoire. J Exp Med (1995) 1.13
T cell positive selection by a high density, low affinity ligand. Proc Natl Acad Sci U S A (1998) 1.12
Expression and role of the T cell receptor in early thymocyte differentiation in vitro. J Immunol (1987) 1.11
The structure of V alpha and J alpha segments in the mouse. Nucleic Acids Res (1988) 1.11
A method for production of antibodies to human T-cell receptor beta-chain variable regions. Proc Natl Acad Sci U S A (1991) 1.11