Published in J Immunol on September 01, 2004
MyD88-dependent expansion of an immature GR-1(+)CD11b(+) population induces T cell suppression and Th2 polarization in sepsis. J Exp Med (2007) 5.48
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Reversal of long-term sepsis-induced immunosuppression by dendritic cells. Blood (2004) 1.44
Epigenetic regulation of immune cell functions during post-septic immunosuppression. Epigenetics (2011) 1.38
Induction of Bim and Bid gene expression during accelerated apoptosis in severe sepsis. Crit Care (2008) 1.21
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Dendritic cells promote pancreatic viability in mice with acute pancreatitis. Gastroenterology (2011) 1.11
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Decrease of circulating dendritic cells in burn patients. Ann Burns Fire Disasters (2007) 0.92
Heterotrimeric Gα(i) proteins are regulated by lipopolysaccharide and are anti-inflammatory in endotoxemia and polymicrobial sepsis. Biochim Biophys Acta (2011) 0.90
Toll-like receptors 2 and 4 contribute to sepsis-induced depletion of spleen dendritic cells. Infect Immun (2009) 0.90
Myeloid-derived suppressor cells in sepsis: friend or foe? Intensive Care Med (2012) 0.84
High MafB expression following burn augments monocyte commitment and inhibits DC differentiation in hemopoietic progenitors. J Leukoc Biol (2011) 0.83
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Autophagy and ATP-induced anti-apoptosis in antigen presenting cells (APC) follows the cytokine storm in patients after major trauma. J Cell Commun Signal (2011) 0.81
N-acetylcysteine administration is associated with reduced activation of NF-kB and preserves lung dendritic cells function in a zymosan-induced generalized inflammation model. J Clin Immunol (2012) 0.80
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Endogenous Fms-like tyrosine kinase-3 ligand levels are not altered in mice after a severe burn and infection. BMC Immunol (2009) 0.78
Accumulation of DC in lamina propria induced by FMS-like tyrosine kinase 3 ligand aggravates the intestinal inflammatory response during endotoxemia. Inflammation (2010) 0.77
Polymicrobial Sepsis Diminishes Dendritic Cell Numbers and Function Directly Contributing to Impaired Primary CD8 T Cell Responses In Vivo. J Immunol (2016) 0.76
Combination therapy with thymosin alpha1 and dexamethasone helps mice survive sepsis. Inflammation (2014) 0.76
Thymic Stromal Lymphopoietin Improves Survival and Reduces Inflammation in Sepsis. Am J Respir Cell Mol Biol (2016) 0.75
The Role of IFN-β during the Course of Sepsis Progression and Its Therapeutic Potential. Front Immunol (2017) 0.75
Genomic responses in mouse models poorly mimic human inflammatory diseases. Proc Natl Acad Sci U S A (2013) 16.74
A network-based analysis of systemic inflammation in humans. Nature (2005) 12.60
A genomic storm in critically injured humans. J Exp Med (2011) 6.67
MyD88-dependent expansion of an immature GR-1(+)CD11b(+) population induces T cell suppression and Th2 polarization in sepsis. J Exp Med (2007) 5.48
Application of genome-wide expression analysis to human health and disease. Proc Natl Acad Sci U S A (2005) 3.49
Whole blood and leukocyte RNA isolation for gene expression analyses. Physiol Genomics (2004) 3.22
Quantitative proteome analysis of human plasma following in vivo lipopolysaccharide administration using 16O/18O labeling and the accurate mass and time tag approach. Mol Cell Proteomics (2005) 2.50
The Pharmacogenomics Research Network Translational Pharmacogenetics Program: overcoming challenges of real-world implementation. Clin Pharmacol Ther (2013) 2.39
Structural basis for the proinflammatory cytokine activity of high mobility group box 1. Mol Med (2003) 2.30
High dynamic range characterization of the trauma patient plasma proteome. Mol Cell Proteomics (2006) 2.25
Persistent inflammation and immunosuppression: a common syndrome and new horizon for surgical intensive care. J Trauma Acute Care Surg (2012) 2.24
Anti-TNF-alpha therapies: the next generation. Nat Rev Drug Discov (2003) 2.18
The changing pattern and implications of multiple organ failure after blunt injury with hemorrhagic shock. Crit Care Med (2012) 2.17
Benchmarking outcomes in the critically injured trauma patient and the effect of implementing standard operating procedures. Ann Surg (2012) 2.07
A paradoxical role for myeloid-derived suppressor cells in sepsis and trauma. Mol Med (2010) 2.06
Omega-3 polyunsaturated fatty acid intake and islet autoimmunity in children at increased risk for type 1 diabetes. JAMA (2007) 2.04
Clinical microfluidics for neutrophil genomics and proteomics. Nat Med (2010) 2.02
B cells enhance early innate immune responses during bacterial sepsis. J Exp Med (2011) 1.99
No alterations in the frequency of FOXP3+ regulatory T-cells in type 1 diabetes. Diabetes (2007) 1.99
Comparative proteome analyses of human plasma following in vivo lipopolysaccharide administration using multidimensional separations coupled with tandem mass spectrometry. Proteomics (2005) 1.94
Development of a genomic metric that can be rapidly used to predict clinical outcome in severely injured trauma patients. Crit Care Med (2013) 1.94
Defective innate immunity predisposes murine neonates to poor sepsis outcome but is reversed by TLR agonists. Blood (2008) 1.94
Increased natural CD4+CD25+ regulatory T cells and their suppressor activity do not contribute to mortality in murine polymicrobial sepsis. J Immunol (2006) 1.86
Cell-specific expression and pathway analyses reveal alterations in trauma-related human T cell and monocyte pathways. Proc Natl Acad Sci U S A (2006) 1.82
Interleukin-10: a complex role in the pathogenesis of sepsis syndromes and its potential as an anti-inflammatory drug. Crit Care Med (2002) 1.78
Molecular characterization of the acute inflammatory response to infections with gram-negative versus gram-positive bacteria. Infect Immun (2003) 1.75
Impaired autophagy: A mechanism of mitochondrial dysfunction in anoxic rat hepatocytes. Hepatology (2008) 1.73
Plasma cytokine measurements augment prognostic scores as indicators of outcome in patients with severe sepsis. Shock (2005) 1.71
CD11c+ dendritic cells are required for survival in murine polymicrobial sepsis. J Immunol (2005) 1.71
Longitudinal studies of inter-alpha inhibitor proteins in severely septic patients: a potential clinical marker and mediator of severe sepsis. Crit Care Med (2007) 1.63
A better understanding of why murine models of trauma do not recapitulate the human syndrome. Crit Care Med (2014) 1.62
Human transcriptome array for high-throughput clinical studies. Proc Natl Acad Sci U S A (2011) 1.62
Continuous flow microfluidic device for rapid erythrocyte lysis. Anal Chem (2004) 1.61
CD14 receptor occupancy in severe sepsis: results of a phase I clinical trial with a recombinant chimeric CD14 monoclonal antibody (IC14). Crit Care Med (2004) 1.58
Role of Toll-like receptors in the development of sepsis. Shock (2008) 1.57
Sepsis induces early alterations in innate immunity that impact mortality to secondary infection. J Immunol (2010) 1.54
Increased mortality and altered immunity in neonatal sepsis produced by generalized peritonitis. Shock (2007) 1.50
Type I interferon signaling in hematopoietic cells is required for survival in mouse polymicrobial sepsis by regulating CXCL10. J Exp Med (2010) 1.50
A genomic score prognostic of outcome in trauma patients. Mol Med (2009) 1.48
Targeting the programmed cell death 1: programmed cell death ligand 1 pathway reverses T cell exhaustion in patients with sepsis. Crit Care (2014) 1.48
Aberrant signaling in the TNFalpha/TNF receptor 1 pathway of the NZM2410 lupus-prone mouse. Clin Immunol (2004) 1.41
Analysis of factorial time-course microarrays with application to a clinical study of burn injury. Proc Natl Acad Sci U S A (2010) 1.33
Treatment with GITR agonistic antibody corrects adaptive immune dysfunction in sepsis. Blood (2007) 1.29
Incidence, clinical predictors, genomics, and outcome of acute kidney injury among trauma patients. Ann Surg (2010) 1.27
Cost and Mortality Associated With Postoperative Acute Kidney Injury. Ann Surg (2015) 1.26
Large-scale multiplexed quantitative discovery proteomics enabled by the use of an (18)O-labeled "universal" reference sample. J Proteome Res (2009) 1.24
Induction of chondrocyte apoptosis following impact load. J Orthop Trauma (2003) 1.23
Preclinical models of shock and sepsis: what can they tell us? Shock (2005) 1.23
The origins of cachexia in acute and chronic inflammatory diseases. Nutr Clin Pract (2006) 1.23
Murine antithymocyte globulin therapy alters disease progression in NOD mice by a time-dependent induction of immunoregulation. Diabetes (2007) 1.22
Neutrophil mobilization from the bone marrow during polymicrobial sepsis is dependent on CXCL12 signaling. J Immunol (2011) 1.21
Direct evidence for tumor necrosis factor-alpha signaling in arteriogenesis. Circulation (2002) 1.19
Role of innate immunity in neonatal infection. Am J Perinatol (2013) 1.16
Parallels between cancer and infectious disease. N Engl J Med (2014) 1.16
Biology of interleukin-10 and its regulatory roles in sepsis syndromes. Crit Care Med (2005) 1.16
Biology of tumor necrosis factor-alpha- implications for psoriasis. Exp Dermatol (2004) 1.14
Cytokine profile after lung transplantation: correlation with allograft injury. Ann Thorac Surg (2006) 1.13
Flagellin enhances NK cell proliferation and activation directly and through dendritic cell-NK cell interactions. J Leukoc Biol (2005) 1.12
Superoxide production by macrophages and T cells is critical for the induction of autoreactivity and type 1 diabetes. Diabetes (2011) 1.12
Critical role for CXC ligand 10/CXC receptor 3 signaling in the murine neonatal response to sepsis. Infect Immun (2011) 1.11
Microfluidic isolation of leukocytes from whole blood for phenotype and gene expression analysis. Anal Chem (2006) 1.11
Reduced serum vitamin D-binding protein levels are associated with type 1 diabetes. Diabetes (2011) 1.10
Monitoring the immune response in sepsis: a rational approach to administration of immunoadjuvant therapies. Curr Opin Immunol (2013) 1.09
Neutrophil elastase, MIP-2, and TLR-4 expression during human and experimental sepsis. Shock (2005) 1.09
A dynamic network of transcription in LPS-treated human subjects. BMC Syst Biol (2009) 1.07
Persistent inflammation, immunosuppression, and catabolism syndrome after severe blunt trauma. J Trauma Acute Care Surg (2014) 1.06
Genomic and proteomic determinants of outcome in patients undergoing thoracoabdominal aortic aneurysm repair. J Immunol (2004) 1.06
Plasma proteome response to severe burn injury revealed by 18O-labeled "universal" reference-based quantitative proteomics. J Proteome Res (2010) 1.05
Interleukin-18: a novel prognostic cytokine in bacteria-induced sepsis. Crit Care Med (2006) 1.04
Inhibition of NF-kappa B augments sensitivity to 5-fluorouracil/folinic acid in colon cancer. J Surg Res (2004) 1.04
Roles of vaccinia virus genes E3L and K3L and host genes PKR and RNase L during intratracheal infection of C57BL/6 mice. J Virol (2010) 1.04
Poly-IC preconditioning protects against cerebral and renal ischemia-reperfusion injury. J Cereb Blood Flow Metab (2011) 1.03
Acute kidney injury is associated with early cytokine changes after trauma. J Trauma Acute Care Surg (2013) 1.02
Sepsis and the dendritic cell. Shock (2003) 1.02
Differential toll-like receptor expression after ex vivo lipopolysaccharide exposure in patients with sepsis and following surgical stress. Clin Immunol (2006) 1.01
Protective immunity and defects in the neonatal and elderly immune response to sepsis. J Immunol (2014) 1.01
Cecal ligation and puncture. Curr Protoc Immunol (2010) 1.01
Human leukocyte antigen expression in sepsis: what have we learned? Crit Care Med (2005) 1.00
Functional genomics and gene expression profiling in sepsis: beyond class prediction. Clin Infect Dis (2005) 1.00
Microfluidics-based capture of human neutrophils for expression analysis in blood and bronchoalveolar lavage. Lab Invest (2011) 1.00
A critical role of CpG motifs in a murine peritonitis model by their binding to highly expressed toll-like receptor-9 on liver NKT cells. J Hepatol (2006) 1.00
Microfluidic leukocyte isolation for gene expression analysis in critically ill hospitalized patients. Clin Chem (2008) 0.99
Identification and interpretation of longitudinal gene expression changes in trauma. PLoS One (2010) 0.98
Genome-wide monocytic mRNA expression in polytrauma patients for identification of clinical outcome. Shock (2005) 0.97
Increased lymphoid tissue apoptosis in baboons with bacteremic shock. Shock (2004) 0.97
Pleiotropic IFN-dependent and -independent effects of IRF5 on the pathogenesis of experimental lupus. J Immunol (2012) 0.97