A multi-modular tensegrity model of an actin stress fiber.

PubWeight™: 1.03‹?› | Rank: Top 15%

🔗 View Article (PMC 2603623)

Published in J Biomech on July 15, 2008

Authors

Yaozhi Luo1, Xian Xu, Tanmay Lele, Sanjay Kumar, Donald E Ingber

Author Affiliations

1: Department of Civil Engineering, College of Architecture and Civil Engineering, Zhejiang University, PR China.

Articles citing this

Mechanotransduction at a distance: mechanically coupling the extracellular matrix with the nucleus. Nat Rev Mol Cell Biol (2009) 5.41

Tensegrity, cellular biophysics, and the mechanics of living systems. Rep Prog Phys (2014) 1.06

Sarcomere mechanics in capillary endothelial cells. Biophys J (2009) 1.06

Actin fusion proteins alter the dynamics of mechanically induced cytoskeleton rearrangement. PLoS One (2011) 1.02

From cellular mechanotransduction to biologically inspired engineering: 2009 Pritzker Award Lecture, BMES Annual Meeting October 10, 2009. Ann Biomed Eng (2010) 0.96

Recoil after severing reveals stress fiber contraction mechanisms. Biophys J (2009) 0.95

Involvement of local lamellipodia in endothelial barrier function. PLoS One (2015) 0.88

Actin kinetics shapes cortical network structure and mechanics. Sci Adv (2016) 0.85

Physicochemical control of adult stem cell differentiation: shedding light on potential molecular mechanisms. J Biomed Biotechnol (2010) 0.80

An inverse power-law distribution of molecular bond lifetimes predicts fractional derivative viscoelasticity in biological tissue. Biophys J (2013) 0.79

A mathematical model to study the dynamics of epithelial cellular networks. IEEE/ACM Trans Comput Biol Bioinform (2012) 0.78

Shear-induced force transmission in a multicomponent, multicell model of the endothelium. J R Soc Interface (2014) 0.76

Complexity of the tensegrity structure for dynamic energy and force distribution of cytoskeleton during cell spreading. PLoS One (2010) 0.75

A computational approach to understand phenotypic structure and constitutive mechanics relationships of single cells. Ann Biomed Eng (2012) 0.75

Form-finding model shows how cytoskeleton network stiffness is realized. PLoS One (2013) 0.75

Articles cited by this

Focal adhesions: transmembrane junctions between the extracellular matrix and the cytoskeleton. Annu Rev Cell Biol (1988) 14.18

Mechanotransduction across the cell surface and through the cytoskeleton. Science (1993) 14.01

Atomic structure of the actin:DNase I complex. Nature (1990) 11.86

Atomic model of the actin filament. Nature (1990) 11.33

Flexural rigidity of microtubules and actin filaments measured from thermal fluctuations in shape. J Cell Biol (1993) 9.84

Nascent focal adhesions are responsible for the generation of strong propulsive forces in migrating fibroblasts. J Cell Biol (2001) 6.32

Cellular mechanotransduction: putting all the pieces together again. FASEB J (2006) 5.84

Tensegrity I. Cell structure and hierarchical systems biology. J Cell Sci (2003) 4.36

Actin, alpha-actinin, and tropomyosin interaction in the structural organization of actin filaments in nonmuscle cells. J Cell Biol (1976) 4.23

Viscoelastic retraction of single living stress fibers and its impact on cell shape, cytoskeletal organization, and extracellular matrix mechanics. Biophys J (2006) 4.06

Direct measurement of stiffness of single actin filaments with and without tropomyosin by in vitro nanomanipulation. Proc Natl Acad Sci U S A (1994) 3.65

Movement and self-control in protein assemblies. Quasi-equivalence revisited. Biophys J (1980) 2.51

Stress fiber sarcomeres of fibroblasts are contractile. Cell (1980) 2.45

Altering the cellular mechanical force balance results in integrated changes in cell, cytoskeletal and nuclear shape. J Cell Sci (1992) 2.13

Simultaneous stretching and contraction of stress fibers in vivo. Mol Biol Cell (2004) 2.12

Tensile properties of single stress fibers isolated from cultured vascular smooth muscle cells. J Biomech (2005) 1.95

Rho-kinase--mediated contraction of isolated stress fibers. J Cell Biol (2001) 1.92

Organization and function of stress fibers in cells in vitro and in situ. A review. Cell Muscle Motil (1984) 1.85

Stress fiber organization regulated by MLCK and Rho-kinase in cultured human fibroblasts. Am J Physiol Cell Physiol (2001) 1.81

The molecular organization of myosin in stress fibers of cultured cells. J Cell Biol (1986) 1.80

Filament compliance and tension transients in muscle. J Muscle Res Cell Motil (1996) 1.67

Isolation and contraction of the stress fiber. Mol Biol Cell (1998) 1.61

A microstructural approach to cytoskeletal mechanics based on tensegrity. J Theor Biol (1996) 1.53

The modular structure of actin-regulatory proteins. Curr Opin Cell Biol (1998) 1.46

Buckling of actin stress fibers: a new wrinkle in the cytoskeletal tapestry. Cell Motil Cytoskeleton (2002) 1.39

3-D nanomechanics of an erythrocyte junctional complex in equibiaxial and anisotropic deformations. Ann Biomed Eng (2005) 1.13

A computational tensegrity model predicts dynamic rheological behaviors in living cells. Ann Biomed Eng (2004) 1.09

Models of cytoskeletal mechanics of adherent cells. Biomech Model Mechanobiol (2002) 1.02

A cellular tensegrity model to analyse the structural viscoelasticity of the cytoskeleton. J Theor Biol (2002) 0.95

A quantitative model of cellular elasticity based on tensegrity. J Biomech Eng (2000) 0.95

Modeling virus self-assembly pathways: avoiding dynamics using geometric constraint decomposition. J Comput Biol (2006) 0.89

Organization of the cytoskeleton in square fibroblasts. Cell Motil (1982) 0.84

Tensegrity architecture explains linear stiffening and predicts softening of living cells. J Biomech (2000) 0.82

Articles by these authors

Polycystins 1 and 2 mediate mechanosensation in the primary cilium of kidney cells. Nat Genet (2003) 13.33

Transcriptome-wide noise controls lineage choice in mammalian progenitor cells. Nature (2008) 7.60

Reconstituting organ-level lung functions on a chip. Science (2010) 5.75

Mechanotransduction at a distance: mechanically coupling the extracellular matrix with the nucleus. Nat Rev Mol Cell Biol (2009) 5.41

Draft genome of the filarial nematode parasite Brugia malayi. Science (2007) 5.28

The Wolbachia genome of Brugia malayi: endosymbiont evolution within a human pathogenic nematode. PLoS Biol (2005) 4.28

Viscoelastic retraction of single living stress fibers and its impact on cell shape, cytoskeletal organization, and extracellular matrix mechanics. Biophys J (2006) 4.06

Cell fates as high-dimensional attractor states of a complex gene regulatory network. Phys Rev Lett (2005) 3.90

Microtubules can bear enhanced compressive loads in living cells because of lateral reinforcement. J Cell Biol (2006) 3.63

Directional control of lamellipodia extension by constraining cell shape and orienting cell tractional forces. FASEB J (2002) 3.45

A mechanosensitive transcriptional mechanism that controls angiogenesis. Nature (2009) 3.44

The mechanical rigidity of the extracellular matrix regulates the structure, motility, and proliferation of glioma cells. Cancer Res (2009) 3.42

Shear-activated nanotherapeutics for drug targeting to obstructed blood vessels. Science (2012) 3.33

Endothelial cilia are fluid shear sensors that regulate calcium signaling and nitric oxide production through polycystin-1. Circulation (2008) 3.33

A rapid protocol for the prevention of contrast-induced renal dysfunction: the RAPPID study. J Am Coll Cardiol (2003) 3.29

Mechanical control of tissue and organ development. Development (2010) 3.18

Cellular adaptation to mechanical stress: role of integrins, Rho, cytoskeletal tension and mechanosensitive ion channels. J Cell Sci (2006) 2.98

Gene Expression Dynamics Inspector (GEDI): for integrative analysis of expression profiles. Bioinformatics (2003) 2.92

From 3D cell culture to organs-on-chips. Trends Cell Biol (2011) 2.83

Cell shape provides global control of focal adhesion assembly. Biochem Biophys Res Commun (2003) 2.71

Mechanical forces alter zyxin unbinding kinetics within focal adhesions of living cells. J Cell Physiol (2006) 2.62

A human disease model of drug toxicity-induced pulmonary edema in a lung-on-a-chip microdevice. Sci Transl Med (2012) 2.52

Micropatterning tractional forces in living cells. Cell Motil Cytoskeleton (2002) 2.45

High-betweenness proteins in the yeast protein interaction network. J Biomed Biotechnol (2005) 2.44

Cell tension, matrix mechanics, and cancer development. Cancer Cell (2005) 2.42

Mechanotransduction: all signals point to cytoskeleton, matrix, and integrins. Sci STKE (2002) 2.36

Human gut-on-a-chip inhabited by microbial flora that experiences intestinal peristalsis-like motions and flow. Lab Chip (2012) 2.36

Nanomagnetic actuation of receptor-mediated signal transduction. Nat Nanotechnol (2007) 2.22

Microengineered physiological biomimicry: organs-on-chips. Lab Chip (2012) 2.21

The interaction of attention and action: from seeing action to acting on perception. Br J Psychol (2009) 2.14

Control of basement membrane remodeling and epithelial branching morphogenesis in embryonic lung by Rho and cytoskeletal tension. Dev Dyn (2005) 2.13

Intracellular stress tomography reveals stress focusing and structural anisotropy in cytoskeleton of living cells. Am J Physiol Cell Physiol (2003) 2.09

Low urine vascular endothelial growth factor levels are associated with mechanical ventilation, bronchopulmonary dysplasia and retinopathy of prematurity. Neonatology (2013) 2.06

Functional characterization of TRPV4 as an osmotically sensitive ion channel in porcine articular chondrocytes. Arthritis Rheum (2009) 2.02

Role of RhoA, mDia, and ROCK in cell shape-dependent control of the Skp2-p27kip1 pathway and the G1/S transition. J Biol Chem (2004) 1.98

Combined microfluidic-micromagnetic separation of living cells in continuous flow. Biomed Microdevices (2006) 1.96

Loss of polycystin-1 in human cyst-lining epithelia leads to ciliary dysfunction. J Am Soc Nephrol (2006) 1.95

Self-assembly of three-dimensional prestressed tensegrity structures from DNA. Nat Nanotechnol (2010) 1.95

Micromagnetic-microfluidic blood cleansing device. Lab Chip (2009) 1.95

Quantitative evaluation of AgNORs in bone tumours. Pathology (2003) 1.92

Independent regulation of tumor cell migration by matrix stiffness and confinement. Proc Natl Acad Sci U S A (2012) 1.89

Geometric determinants of directional cell motility revealed using microcontact printing. Langmuir (2003) 1.85

TRPV4 channels mediate cyclic strain-induced endothelial cell reorientation through integrin-to-integrin signaling. Circ Res (2009) 1.84

Mechanochemical control of mesenchymal condensation and embryonic tooth organ formation. Dev Cell (2011) 1.82

Angiopoietin-1 requires p190 RhoGAP to protect against vascular leakage in vivo. J Biol Chem (2007) 1.81

A complex of the IL-1 homologue IL-1F7b and IL-18-binding protein reduces IL-18 activity. Proc Natl Acad Sci U S A (2002) 1.78

Mechanosensitive mechanisms in transcriptional regulation. J Cell Sci (2012) 1.76

Chondroprotective role of the osmotically sensitive ion channel transient receptor potential vanilloid 4: age- and sex-dependent progression of osteoarthritis in Trpv4-deficient mice. Arthritis Rheum (2010) 1.75

Selective chemical treatment of cellular microdomains using multiple laminar streams. Chem Biol (2003) 1.74

Epoxyeicosanoids stimulate multiorgan metastasis and tumor dormancy escape in mice. J Clin Invest (2011) 1.74

Probing cellular mechanobiology in three-dimensional culture with collagen-agarose matrices. Biomaterials (2009) 1.72

Estrogen-receptor-alpha exchange and chromatin dynamics are ligand- and domain-dependent. J Cell Sci (2006) 1.72

Directional control of cell motility through focal adhesion positioning and spatial control of Rac activation. FASEB J (2008) 1.71

Biophysical regulation of tumor cell invasion: moving beyond matrix stiffness. Integr Biol (Camb) (2011) 1.68

Extracellular matrix controls myosin light chain phosphorylation and cell contractility through modulation of cell shape and cytoskeletal prestress. Am J Physiol Cell Physiol (2004) 1.68

NF-kappa B mediates the stimulation of cytokine and chemokine expression by human articular chondrocytes in response to fibronectin fragments. J Immunol (2005) 1.68

Infection with cytomegalovirus in patients with inflammatory bowel disease: prevalence, clinical significance and outcome. J Med Microbiol (2004) 1.67

Tumor-derived endothelial cells exhibit aberrant Rho-mediated mechanosensing and abnormal angiogenesis in vitro. Proc Natl Acad Sci U S A (2008) 1.60

Paper-supported 3D cell culture for tissue-based bioassays. Proc Natl Acad Sci U S A (2009) 1.60

Inhibition of endothelial cell migration by thrombospondin-1 type-1 repeats is mediated by beta1 integrins. J Cell Biol (2005) 1.59

Proteoglycan degradation after injurious compression of bovine and human articular cartilage in vitro: interaction with exogenous cytokines. Arthritis Rheum (2003) 1.59

Alpha-actinin-4 is required for normal podocyte adhesion. J Biol Chem (2006) 1.58

Multistable and multistep dynamics in neutrophil differentiation. BMC Cell Biol (2006) 1.56

Gut-on-a-Chip microenvironment induces human intestinal cells to undergo villus differentiation. Integr Biol (Camb) (2013) 1.54

Indian doctor in protest after using Viagra to save "blue babies". BMJ (2002) 1.54

Noise-driven stem cell and progenitor population dynamics. PLoS One (2008) 1.52

Human kidney proximal tubule-on-a-chip for drug transport and nephrotoxicity assessment. Integr Biol (Camb) (2013) 1.52

Forty-year journey of angiogenesis translational research. Sci Transl Med (2011) 1.51

Filamin links cell shape and cytoskeletal structure to Rho regulation by controlling accumulation of p190RhoGAP in lipid rafts. J Cell Sci (2007) 1.51

Structural basis for peptidoglycan binding by peptidoglycan recognition proteins. Proc Natl Acad Sci U S A (2004) 1.50

A non-genetic basis for cancer progression and metastasis: self-organizing attractors in cell regulatory networks. Breast Dis (2007) 1.49

Ascorbic acid deficiency activates cell death and disease resistance responses in Arabidopsis. Plant Physiol (2005) 1.49

Mechanobiology and developmental control. Annu Rev Cell Dev Biol (2013) 1.48

Scientists accuse animal rights activists of stifling research. BMJ (2002) 1.46

Cytoskeletal control of growth and cell fate switching. Curr Opin Cell Biol (2009) 1.45

Microfabrication of human organs-on-chips. Nat Protoc (2013) 1.44

Global cytoskeletal control of mechanotransduction in kidney epithelial cells. Exp Cell Res (2004) 1.43

Filamin A regulates focal adhesion disassembly and suppresses breast cancer cell migration and invasion. J Exp Med (2010) 1.43

Exercise training decreases store-operated Ca2+entry associated with metabolic syndrome and coronary atherosclerosis. Cardiovasc Res (2009) 1.43

Actomyosin tension exerted on the nucleus through nesprin-1 connections influences endothelial cell adhesion, migration, and cyclic strain-induced reorientation. Biophys J (2010) 1.43

Retracted A meta-analysis of external fixator versus intramedullary nails for open tibial fracture fixation. J Orthop Surg Res (2014) 1.42

Sequential involvement of Cdk1, mTOR and p53 in apoptosis induced by the HIV-1 envelope. EMBO J (2002) 1.42

Ablation of cytoskeletal filaments and mitochondria in live cells using a femtosecond laser nanoscissor. Mech Chem Biosyst (2005) 1.40

Ratio of girls to boys in India continues to decline. BMJ (2003) 1.40

Therapeutic potential of mesenchymal stem cells producing interferon-alpha in a mouse melanoma lung metastasis model. Stem Cells (2008) 1.38

Millions more at risk of arsenic poisoning than previously thought. BMJ (2003) 1.38

Schizosaccharomyces pombe Swi1, Swi3, and Hsk1 are components of a novel S-phase response pathway to alkylation damage. Mol Cell Biol (2005) 1.37

Aspiration cytology of epidermoid cyst of terminal phalanx. Diagn Cytopathol (2002) 1.37

Micromechanical control of cell and tissue development: implications for tissue engineering. Adv Drug Deliv Rev (2007) 1.36

A combined micromagnetic-microfluidic device for rapid capture and culture of rare circulating tumor cells. Lab Chip (2012) 1.35

ABL2/ARG tyrosine kinase mediates SEMA3F-induced RhoA inactivation and cytoskeleton collapse in human glioma cells. J Biol Chem (2008) 1.34

Isoform-specific contributions of alpha-actinin to glioma cell mechanobiology. PLoS One (2009) 1.34

Placement of half-pins for supra-acetabular external fixation: an anatomic study. Clin Orthop Relat Res (2003) 1.33

Endosymbiont DNA in endobacteria-free filarial nematodes indicates ancient horizontal genetic transfer. PLoS One (2010) 1.33

India s treatment programme for AIDS is premature. BMJ (2004) 1.32

An RNA isolation system for plant tissues rich in secondary metabolites. BMC Res Notes (2011) 1.32

Mechanical properties of individual focal adhesions probed with a magnetic microneedle. Biochem Biophys Res Commun (2004) 1.29