Digoxin and its derivatives suppress TH17 cell differentiation by antagonizing RORγt activity.

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Published in Nature on March 27, 2011

Authors

Jun R Huh1, Monica W L Leung, Pengxiang Huang, Daniel A Ryan, Michael R Krout, Raghu R V Malapaka, Jonathan Chow, Nicolas Manel, Maria Ciofani, Sangwon V Kim, Adolfo Cuesta, Fabio R Santori, Juan J Lafaille, H Eric Xu, David Y Gin, Fraydoon Rastinejad, Dan R Littman

Author Affiliations

1: Molecular Pathogenesis Program, The Kimmel Center for Biology and Medicine of the Skirball Institute, New York University School of Medicine, New York, New York 10016, USA.

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