Published in Biochem Biophys Res Commun on August 15, 1991
Channelrhodopsin-2, a directly light-gated cation-selective membrane channel. Proc Natl Acad Sci U S A (2003) 15.17
Two rhodopsins mediate phototaxis to low- and high-intensity light in Chlamydomonas reinhardtii. Proc Natl Acad Sci U S A (2002) 4.02
Multiple photocycles of channelrhodopsin. Biophys J (2005) 2.40
The nature of rhodopsin-triggered photocurrents in Chlamydomonas. I. Kinetics and influence of divalent ions. Biophys J (1996) 1.58
Photoinduced electric currents in carotenoid-deficient Chlamydomonas mutants reconstituted with retinal and its analogs. Biophys J (1994) 1.48
Evidence for a light-induced H(+) conductance in the eye of the green alga Chlamydomonas reinhardtii. Biophys J (2002) 1.33
Comparative study of phototactic and photophobic receptor chromophore properties in Chlamydomonas reinhardtii. Biophys J (1993) 1.27
Chlamydomonas sensory rhodopsins A and B: cellular content and role in photophobic responses. Biophys J (2004) 1.11
Cell type-specific and time-dependent light exposure contribute to silencing in neurons expressing Channelrhodopsin-2. Elife (2014) 1.04
Photosensory functions of channelrhodopsins in native algal cells. Photochem Photobiol (2009) 1.03
ptx1, a nonphototactic mutant of Chlamydomonas, lacks control of flagellar dominance. J Cell Biol (1993) 0.99
How 5000 independent rowers coordinate their strokes in order to row into the sunlight: phototaxis in the multicellular green alga Volvox. BMC Biol (2010) 0.97
Role of a helix B lysine residue in the photoactive site in channelrhodopsins. Biophys J (2014) 0.82
Photoreceptor current and photoorientation in chlamydomonas mediated by 9-demethylchlamyrhodopsin. Biophys J (2001) 0.80
All-atom empirical potential for molecular modeling and dynamics studies of proteins. J Phys Chem B (1998) 54.00
Targeted disruption of the MyD88 gene results in loss of IL-1- and IL-18-mediated function. Immunity (1998) 18.12
The use of statins: a case of misleading priorities? BMJ (1997) 13.35
Urban residential environments and senior citizens' longevity in megacity areas: the importance of walkable green spaces. J Epidemiol Community Health (2002) 7.79
Evidence for the effects of HIV antibody counseling and testing on risk behaviors. JAMA (1991) 7.35
Essential role of Stat6 in IL-4 signalling. Nature (1996) 6.56
Unintended changes in cognition, mood, and behavior arising from cell-based interventions for neurological conditions: ethical challenges. Am J Bioeth (2009) 6.13
Domestic violence against women. Incidence and prevalence in an emergency department population. JAMA (1995) 5.89
Guidelines for using human event-related potentials to study cognition: recording standards and publication criteria. Psychophysiology (2000) 5.83
The IKKbeta subunit of IkappaB kinase (IKK) is essential for nuclear factor kappaB activation and prevention of apoptosis. J Exp Med (1999) 5.79
Risk factors for hepatocellular carcinoma among patients with chronic liver disease. N Engl J Med (1993) 5.32
Activation of interferon-gamma inducing factor mediated by interleukin-1beta converting enzyme. Science (1997) 5.16
Abnormal morphogenesis but intact IKK activation in mice lacking the IKKalpha subunit of IkappaB kinase. Science (1999) 5.15
Epilepsy and exacerbation of brain injury in mice lacking the glutamate transporter GLT-1. Science (1997) 5.13
Defective NK cell activity and Th1 response in IL-18-deficient mice. Immunity (1998) 4.70
Action spectra for phytochrome A- and B-specific photoinduction of seed germination in Arabidopsis thaliana. Proc Natl Acad Sci U S A (1996) 4.48
Cutting edge: endotoxin tolerance in mouse peritoneal macrophages correlates with down-regulation of surface toll-like receptor 4 expression. J Immunol (2000) 4.10
Smad4 and FAST-1 in the assembly of activin-responsive factor. Nature (1997) 3.66
Retrospective assessment of prepubertal major depression with the Kiddie-SADS-e. J Am Acad Child Psychiatry (1982) 3.57
IL-12 up-regulates IL-18 receptor expression on T cells, Th1 cells, and B cells: synergism with IL-18 for IFN-gamma production. J Immunol (1998) 3.56
Isolation and one-step preparation of A2E and iso-A2E, fluorophores from human retinal pigment epithelium. Proc Natl Acad Sci U S A (1998) 3.54
Ultrasonic acoustic emissions from the sapwood of cedar and hemlock : an examination of three hypotheses regarding cavitations. Plant Physiol (1984) 3.27
The influence on numerical taxonomic similarities of errors in microbiological tests. J Gen Microbiol (1972) 3.16
Chemical nature of the light emitter of the Aequorea green fluorescent protein. Proc Natl Acad Sci U S A (1996) 3.12
IKKalpha provides an essential link between RANK signaling and cyclin D1 expression during mammary gland development. Cell (2001) 3.10
A rhodopsin is the functional photoreceptor for phototaxis in the unicellular eukaryote Chlamydomonas. Nature (1984) 3.09
Parathyroid hormone-related protein purified from a human lung cancer cell line. Proc Natl Acad Sci U S A (1987) 3.06
Wound-inducible expression of a potato inhibitor II-chloramphenicol acetyltransferase gene fusion in transgenic tobacco plants. Proc Natl Acad Sci U S A (1987) 3.04
The gene mutated in ataxia-ocular apraxia 1 encodes the new HIT/Zn-finger protein aprataxin. Nat Genet (2001) 3.01
The S receptor kinase determines self-incompatibility in Brassica stigma. Nature (2000) 2.96
The lipofuscin fluorophore A2E mediates blue light-induced damage to retinal pigmented epithelial cells. Invest Ophthalmol Vis Sci (2000) 2.92
A2E, a lipofuscin fluorophore, in human retinal pigmented epithelial cells in culture. Invest Ophthalmol Vis Sci (1999) 2.89
Development of the mouse inner ear and origin of its sensory organs. J Neurosci (1998) 2.81
Event-related potential (ERP) studies of memory encoding and retrieval: a selective review. Microsc Res Tech (2000) 2.78
The London Position Statement of the World Congress of Gastroenterology on Biological Therapy for IBD with the European Crohn's and Colitis Organization: when to start, when to stop, which drug to choose, and how to predict response? Am J Gastroenterol (2010) 2.74
Requirement for p38alpha in erythropoietin expression: a role for stress kinases in erythropoiesis. Cell (2000) 2.74
Drosophila CtBP: a Hairy-interacting protein required for embryonic segmentation and hairy-mediated transcriptional repression. EMBO J (1998) 2.74
Diversity revealed by a novel family of cadherins expressed in neurons at a synaptic complex. Neuron (1998) 2.73
Leg ulcers in patients with sickle cell disease. Blood (1989) 2.72
Intelligence and the frontal lobe: the organization of goal-directed behavior. Cogn Psychol (1996) 2.69
Direct ligand-receptor complex interaction controls Brassica self-incompatibility. Nature (2001) 2.69
Identification of retinal isomers isolated from bacteriorhodopsin. Biochemistry (1977) 2.67
Impairment of suckling response, trigeminal neuronal pattern formation, and hippocampal LTD in NMDA receptor epsilon 2 subunit mutant mice. Neuron (1996) 2.62
Hepatocyte growth factor gene therapy of liver cirrhosis in rats. Nat Med (1999) 2.51
The pollen determinant of self-incompatibility in Brassica campestris. Proc Natl Acad Sci U S A (2000) 2.50
A triarchic model of P300 amplitude. Psychophysiology (1986) 2.48
On the structural diversity of fern antheridiogens. Naturwissenschaften (1972) 2.47
The effect of tetraethylammonium chloride on potassium permeability in the smooth muscle cell membrane of canine trachea. J Physiol (1981) 2.45
Regulation of interferon-gamma production by IL-12 and IL-18. Curr Opin Immunol (1998) 2.42
Prefrontal and cingulate unit activity during timing behavior in the monkey. Brain Res (1979) 2.41
Ampulla cardiomyopathy ('Takotusbo' cardiomyopathy)--reversible left ventricular dysfunction: with ST segment elevation. Jpn Circ J (2000) 2.39
IL-18, although antiallergic when administered with IL-12, stimulates IL-4 and histamine release by basophils. Proc Natl Acad Sci U S A (1999) 2.35
Benzo(a)pyrene diol epoxides as intermediates in nucleic acid binding in vitro and in vivo. Science (1976) 2.34
The absence of interleukin 1 receptor-related T1/ST2 does not affect T helper cell type 2 development and its effector function. J Exp Med (1999) 2.32
Activation of ZAP-70 kinase activity by phosphorylation of tyrosine 493 is required for lymphocyte antigen receptor function. EMBO J (1995) 2.31
Gap junction formation between reaggregated Novikoff hepatoma cells. Proc Natl Acad Sci U S A (1974) 2.30
Isolation and indentification on meiosis inducing substance in starfish Asterias amurensis. Nature (1969) 2.29
Impairment of AMPA receptor function in cerebellar granule cells of ataxic mutant mouse stargazer. J Neurosci (1999) 2.27
Coordinate up-regulation of hypoxia inducible factor (HIF)-1alpha and HIF-1 target genes during multi-stage epidermal carcinogenesis and wound healing. Cancer Res (2000) 2.27
State of the art of self-etch adhesives. Dent Mater (2010) 2.26
Toward a functional categorization of slow waves. Psychophysiology (1988) 2.26
Longitudinal study of cerebrospinal fluid levels of tau, A beta1-40, and A beta1-42(43) in Alzheimer's disease: a study in Japan. Ann Neurol (1998) 2.25
The role of hydrated silica, titania, and alumina in inducing apatite on implants. J Biomed Mater Res (1994) 2.25
The biosynthesis of A2E, a fluorophore of aging retina, involves the formation of the precursor, A2-PE, in the photoreceptor outer segment membrane. J Biol Chem (2000) 2.25
Interleukin-18: a novel cytokine that augments both innate and acquired immunity. Adv Immunol (1998) 2.23
Flat neoplastic lesions of the colon and rectum detected by high-resolution video endoscopy and chromoscopy. Gastrointest Endosc (1995) 2.22
Structure of the fluorescent Y base from yeast phenylalanine transfer ribonucleic acid. J Am Chem Soc (1970) 2.21
Expression of the BNLF-1 oncogene of Epstein-Barr virus in the skin of transgenic mice induces hyperplasia and aberrant expression of keratin 6. Cell (1990) 2.20
Mental-physical co-morbidity and its relationship with disability: results from the World Mental Health Surveys. Psychol Med (2008) 2.15
Delay activity of orbital and lateral prefrontal neurons of the monkey varying with different rewards. Cereb Cortex (2000) 2.15
Genomic organization of the S locus: Identification and characterization of genes in SLG/SRK region of S(9) haplotype of Brassica campestris (syn. rapa). Genetics (1999) 2.12
Laparoscopic observations of congenital anomalies of the liver. Gastrointest Endosc (1998) 2.10
Electrophysiology of smooth muscle of the small intestine of some mammals. J Physiol (1986) 2.10
Statistical analysis of the 5' untranslated region of human mRNA using "Oligo-Capped" cDNA libraries. Genomics (2000) 2.09
Osteopontin--a molecule for all seasons. QJM (2002) 2.09
Phosphorylation of SLP-76 by the ZAP-70 protein-tyrosine kinase is required for T-cell receptor function. J Biol Chem (1996) 2.09
Response of psoriasis to a lymphocyte-selective toxin (DAB389IL-2) suggests a primary immune, but not keratinocyte, pathogenic basis. Nat Med (1995) 2.09
An autopsy case of troglitazone-induced fulminant hepatitis. Diabetes Care (1998) 2.08
Transplantation of in vitro-expanded fetal neural progenitor cells results in neurogenesis and functional recovery after spinal cord contusion injury in adult rats. J Neurosci Res (2002) 2.06
Purified poloxamer 188 for treatment of acute vaso-occlusive crisis of sickle cell disease: A randomized controlled trial. JAMA (2001) 2.06
3-(3-amino-3-carboxy-n-propyl)uridine. The structure of the nucleoside in Escherichia coli transfer ribonucleic acid that reacts with phenoxyacetoxysuccinimide. Biochemistry (1974) 2.06
Adiponectin suppresses colorectal carcinogenesis under the high-fat diet condition. Gut (2008) 2.05
Phylogenetic relationships between toxic and non-toxic strains of the genus Microcystis based on 16S to 23S internal transcribed spacer sequence. FEMS Microbiol Lett (1999) 2.04
Treatment of polycystic kidney disease with a novel tyrosine kinase inhibitor. Kidney Int (2000) 2.03
Peer Reviewed: MTBE-To What Extent Will Past Releases Contaminate Community Water Supply Wells? Environ Sci Technol (2000) 2.02
HIV seroprevalence surveys in sexually transmitted disease clinics. Public Health Rep (1990) 2.02
Semantide- and chemotaxonomy-based analyses of some problematic phenotypic clusters of slowly growing mycobacteria, a cooperative study of the International Working Group on Mycobacterial Taxonomy. Int J Syst Bacteriol (1996) 2.02
Direct regulation of ZAP-70 by SHP-1 in T cell antigen receptor signaling. Science (1996) 1.99
Eagle's syndrome (elongated styloid process) South Med J (1997) 1.98
Mechanism of deoxyadenosine and 2-chlorodeoxyadenosine toxicity to nondividing human lymphocytes. J Clin Invest (1985) 1.98
Immunoserological comparison of 104-kilodalton proteins associated with hemolysis and cytolysis in Actinobacillus pleuropneumoniae, Actinobacillus suis, Pasteurella haemolytica, and Escherichia coli. Infect Immun (1989) 1.96
IL-18 and IL-12 induce intestinal inflammation and fatty liver in mice in an IFN-gamma dependent manner. Gut (2000) 1.95
Airway management device (AMD) for airway control in percutaneous dilatational tracheostomy. Anaesthesia (2000) 1.93
New model of oropharyngeal candidiasis in mice. Antimicrob Agents Chemother (2001) 1.93
Interleukin 18 together with interleukin 12 inhibits IgE production by induction of interferon-gamma production from activated B cells. Proc Natl Acad Sci U S A (1997) 1.92
Ataxia with oculomotor apraxia type 2: clinical, biological and genotype/phenotype correlation study of a cohort of 90 patients. Brain (2009) 1.91
Isolation and structure of a covalent cross-link adduct between mitomycin C and DNA. Science (1987) 1.91
Motor discoordination and increased susceptibility to cerebellar injury in GLAST mutant mice. Eur J Neurosci (1998) 1.90
Cross-calibration of body-composition techniques against dual-energy X-ray absorptiometry in young children. Am J Clin Nutr (1996) 1.90