Published in Haematologica on September 01, 2008
Elevated interleukin-21 correlated to Th17 and Th1 cells in patients with immune thrombocytopenia. J Clin Immunol (2009) 1.18
T cell immune abnormalities in immune thrombocytopenia. J Hematol Oncol (2014) 0.94
Repeated courses of rituximab in chronic ITP: Three different regimens. Am J Hematol (2009) 0.92
Effects of high-dose dexamethasone on regulating interleukin-22 production and correcting Th1 and Th22 polarization in immune thrombocytopenia. J Clin Immunol (2012) 0.92
MicroRNA regulate immunological pathways in T-cells in immune thrombocytopenia (ITP). Blood (2013) 0.84
Interleukin 27 inhibits cytotoxic T-lymphocyte-mediated platelet destruction in primary immune thrombocytopenia. Blood (2014) 0.82
The Centenary of Immune Thrombocytopenia - Part 1: Revising Nomenclature and Pathogenesis. Front Pediatr (2016) 0.79
RhIG for the treatment of immune thrombocytopenia: consensus and controversy (CME). Transfusion (2011) 0.77
CD8+ T cells are predominantly protective and required for effective steroid therapy in murine models of immune thrombocytopenia. Blood (2015) 0.77
CD8(+) T cells induce platelet clearance in the liver via platelet desialylation in immune thrombocytopenia. Sci Rep (2016) 0.75
Pathogenesis-oriented approaches for the management of corticosteroid-resistant or relapsedprimary immune thrombocytopenia. Open Med (Wars) (2016) 0.75
Contributions of T lymphocyte abnormalities to therapeutic outcomes in newly diagnosed patients with immune thrombocytopenia. PLoS One (2015) 0.75
Platelet Apoptosis in Adult Immune Thrombocytopenia: Insights into the Mechanism of Damage Triggered by Auto-Antibodies. PLoS One (2016) 0.75
Pathogenesis and Therapeutic Mechanisms in Immune Thrombocytopenia (ITP). J Clin Med (2017) 0.75
Multiplex genome engineering using CRISPR/Cas systems. Science (2013) 55.53
Millisecond-timescale, genetically targeted optical control of neural activity. Nat Neurosci (2005) 28.08
One-step generation of mice carrying mutations in multiple genes by CRISPR/Cas-mediated genome engineering. Cell (2013) 24.00
DNA targeting specificity of RNA-guided Cas9 nucleases. Nat Biotechnol (2013) 19.99
The mutational landscape of head and neck squamous cell carcinoma. Science (2011) 16.88
RNA-guided editing of bacterial genomes using CRISPR-Cas systems. Nat Biotechnol (2013) 15.51
Targeting DNA double-strand breaks with TAL effector nucleases. Genetics (2010) 14.49
Whole-genome sequencing in a patient with Charcot-Marie-Tooth neuropathy. N Engl J Med (2010) 13.57
Double nicking by RNA-guided CRISPR Cas9 for enhanced genome editing specificity. Cell (2013) 13.37
Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk. Nature (2011) 13.25
Genome-wide association study identifies eight loci associated with blood pressure. Nat Genet (2009) 12.44
Driving fast-spiking cells induces gamma rhythm and controls sensory responses. Nature (2009) 11.74
HMDB: a knowledgebase for the human metabolome. Nucleic Acids Res (2008) 11.23
Parvalbumin neurons and gamma rhythms enhance cortical circuit performance. Nature (2009) 10.79
Common genetic determinants of vitamin D insufficiency: a genome-wide association study. Lancet (2010) 8.89
Selection-free zinc-finger-nuclease engineering by context-dependent assembly (CoDA). Nat Methods (2010) 8.86
Phasic firing in dopaminergic neurons is sufficient for behavioral conditioning. Science (2009) 8.76
Neural substrates of awakening probed with optogenetic control of hypocretin neurons. Nature (2007) 8.22
An optical neural interface: in vivo control of rodent motor cortex with integrated fiberoptic and optogenetic technology. J Neural Eng (2007) 7.74
The Genomes of Oryza sativa: a history of duplications. PLoS Biol (2005) 7.67
Genome-wide association study identifies genes for biomarkers of cardiovascular disease: serum urate and dyslipidemia. Am J Hum Genet (2008) 7.33
A transcription activator-like effector toolbox for genome engineering. Nat Protoc (2012) 6.81
Targeting and readout strategies for fast optical neural control in vitro and in vivo. J Neurosci (2007) 6.28
The human serum metabolome. PLoS One (2011) 5.55
Dupilumab in persistent asthma with elevated eosinophil levels. N Engl J Med (2013) 5.29
Randomized trial of oral teriflunomide for relapsing multiple sclerosis. N Engl J Med (2011) 4.93
Excitatory transmission from the amygdala to nucleus accumbens facilitates reward seeking. Nature (2011) 4.58
Mechanisms for human genomic rearrangements. Pathogenetics (2008) 4.54
A TALEN genome-editing system for generating human stem cell-based disease models. Cell Stem Cell (2012) 4.49
The JAK2 inhibitor AZD1480 potently blocks Stat3 signaling and oncogenesis in solid tumors. Cancer Cell (2009) 4.47
Epigenome-wide scans identify differentially methylated regions for age and age-related phenotypes in a healthy ageing population. PLoS Genet (2012) 4.05
The developmental dynamics of the maize leaf transcriptome. Nat Genet (2010) 4.02
Overexpression of long non-coding RNA HOTAIR predicts tumor recurrence in hepatocellular carcinoma patients following liver transplantation. Ann Surg Oncol (2011) 3.88
Rates of adult schizophrenia following prenatal exposure to the Chinese famine of 1959-1961. JAMA (2005) 3.83
Targeted optogenetic stimulation and recording of neurons in vivo using cell-type-specific expression of Channelrhodopsin-2. Nat Protoc (2010) 3.71
Global and local fMRI signals driven by neurons defined optogenetically by type and wiring. Nature (2010) 3.61
Comprehensive interrogation of natural TALE DNA-binding modules and transcriptional repressor domains. Nat Commun (2012) 3.60
Programmable repression and activation of bacterial gene expression using an engineered CRISPR-Cas system. Nucleic Acids Res (2013) 3.51
Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressure. Nat Genet (2011) 3.40
A requirement for CARMA1 in TCR-induced NF-kappa B activation. Nat Immunol (2002) 3.38
Activation of specific interneurons improves V1 feature selectivity and visual perception. Nature (2012) 3.27
Long non-coding RNA MALAT-1 overexpression predicts tumor recurrence of hepatocellular carcinoma after liver transplantation. Med Oncol (2011) 3.24
Reference genome sequence of the model plant Setaria. Nat Biotechnol (2012) 3.21
Priming in systemic plant immunity. Science (2009) 3.11
Chromosome catastrophes involve replication mechanisms generating complex genomic rearrangements. Cell (2011) 3.03
Biological applications of gold nanoparticles. Chem Soc Rev (2008) 3.01
Selection of potential markers for epithelial ovarian cancer with gene expression arrays and recursive descent partition analysis. Clin Cancer Res (2004) 2.96
Genetic evidence supports demic diffusion of Han culture. Nature (2004) 2.92
Reciprocal differentiation and tissue-specific pathogenesis of Th1, Th2, and Th17 cells in graft-versus-host disease. Blood (2009) 2.91
PYPAF1, a PYRIN-containing Apaf1-like protein that assembles with ASC and regulates activation of NF-kappa B. J Biol Chem (2002) 2.88
Crystal structure of the channelrhodopsin light-gated cation channel. Nature (2012) 2.83
The relationship of eosinophilia to intravenous immunoglobulin treatment failure in Kawasaki disease. Pediatr Allergy Immunol (2007) 2.81
Assembly of endocytic machinery around individual influenza viruses during viral entry. Nat Struct Mol Biol (2004) 2.77
In vivo delivery of siRNA to immune cells by conjugation to a TLR9 agonist enhances antitumor immune responses. Nat Biotechnol (2009) 2.76
Accelerated senescence of endothelial progenitor cells in hypertension is related to the reduction of calcitonin gene-related peptide. J Hypertens (2010) 2.68
Functional screening of five PYPAF family members identifies PYPAF5 as a novel regulator of NF-kappaB and caspase-1. FEBS Lett (2002) 2.66
Common genetic variants modulate pathogen-sensing responses in human dendritic cells. Science (2014) 2.63
Triple versus dual antiplatelet therapy in patients with acute ST-segment elevation myocardial infarction undergoing primary percutaneous coronary intervention. Circulation (2009) 2.62
Efficient genome editing in plants using a CRISPR/Cas system. Cell Res (2013) 2.57
Complex rearrangements in patients with duplications of MECP2 can occur by fork stalling and template switching. Hum Mol Genet (2009) 2.50
Increased LIS1 expression affects human and mouse brain development. Nat Genet (2009) 2.45
Inferring reputation promotes the evolution of cooperation in spatial social dilemma games. PLoS One (2012) 2.41
Optogenetic interrogation of dopaminergic modulation of the multiple phases of reward-seeking behavior. J Neurosci (2011) 2.37
Transcription activator-like effector nucleases enable efficient plant genome engineering. Plant Physiol (2012) 2.36
Potential markers that complement expression of CA125 in epithelial ovarian cancer. Gynecol Oncol (2005) 2.34
Influence of the period-dependent circadian clock on diurnal, circadian, and aperiodic gene expression in Drosophila melanogaster. Proc Natl Acad Sci U S A (2002) 2.33
First-in-human trial of a STAT3 decoy oligonucleotide in head and neck tumors: implications for cancer therapy. Cancer Discov (2012) 2.31
Frequent mutation of the PI3K pathway in head and neck cancer defines predictive biomarkers. Cancer Discov (2013) 2.29
Genome-wide association study of blood pressure extremes identifies variant near UMOD associated with hypertension. PLoS Genet (2010) 2.24
Unexpected consequences of a sudden and massive transposon amplification on rice gene expression. Nature (2009) 2.24
Tunneling and coupled motion in the Escherichia coli dihydrofolate reductase catalysis. J Am Chem Soc (2004) 2.21
Association between the various mutations in viral core promoter region to different stages of hepatitis B, ranging of asymptomatic carrier state to hepatocellular carcinoma. Am J Gastroenterol (2010) 2.20
Role of SMAD and non-SMAD signals in the development of Th17 and regulatory T cells. J Immunol (2010) 2.20
Re-emerging superconductivity at 48 kelvin in iron chalcogenides. Nature (2012) 2.13
Improved expression of halorhodopsin for light-induced silencing of neuronal activity. Brain Cell Biol (2008) 2.12
Iterative capped assembly: rapid and scalable synthesis of repeat-module DNA such as TAL effectors from individual monomers. Nucleic Acids Res (2012) 2.09
Low-molecular-weight heparin versus unfractionated heparin in acute ST-segment elevation myocardial infarction patients undergoing primary percutaneous coronary intervention with drug-eluting stents. Am Heart J (2010) 2.09
NIPA2 located in 15q11.2 is mutated in patients with childhood absence epilepsy. Hum Genet (2012) 2.08
Isoflurane causes greater neurodegeneration than an equivalent exposure of sevoflurane in the developing brain of neonatal mice. Anesthesiology (2010) 2.08
Autism and other neuropsychiatric symptoms are prevalent in individuals with MeCP2 duplication syndrome. Ann Neurol (2009) 2.07
Pharmaceutical applications of hot-melt extrusion: part I. Drug Dev Ind Pharm (2007) 2.07
Transarticular screw and C1 hook fixation for os odontoideum with atlantoaxial dislocation. World Neurosurg (2011) 2.07
Minimally invasive pedicle screw fixation combined with percutaneous vertebroplasty in the surgical treatment of thoracolumbar osteoporosis fracture. J Neurosurg Spine (2013) 2.05
Schizophrenia-related neural and behavioral phenotypes in transgenic mice expressing truncated Disc1. J Neurosci (2008) 2.04
A genome-wide association study identifies an osteoarthritis susceptibility locus on chromosome 7q22. Arthritis Rheum (2010) 2.02
Effects of estrogen depletion on angiogenesis in estrogen-receptor-positive breast carcinoma--an immunohistochemical study of vasohibin-1 and CD31 with correlation to pathobiological response of the patients in neoadjuvant aromatase inhibitor therapy. Expert Opin Ther Targets (2012) 2.00
Genome-wide scan for familial nasopharyngeal carcinoma reveals evidence of linkage to chromosome 4. Nat Genet (2002) 2.00
Nucleation and growth of nanoparticles in the atmosphere. Chem Rev (2011) 1.99
Metabolic syndrome is associated with better nutritional status, but not with cardiovascular disease or all-cause mortality in patients on haemodialysis. Arch Cardiovasc Dis (2012) 1.99
The Plk1-dependent phosphoproteome of the early mitotic spindle. Mol Cell Proteomics (2010) 1.91
Dissecting neural function using targeted genome engineering technologies. ACS Chem Neurosci (2012) 1.89
Targeting Stat3 abrogates EGFR inhibitor resistance in cancer. Clin Cancer Res (2012) 1.89
Hepatic resection as a safe and effective treatment for hepatocellular carcinoma involving a single large tumor, multiple tumors, or macrovascular invasion. Medicine (Baltimore) (2015) 1.88
A quantitative fluorescence study of protein monolayer formation on colloidal nanoparticles. Nat Nanotechnol (2009) 1.85
Role of differentiation of liver sinusoidal endothelial cells in progression and regression of hepatic fibrosis in rats. Gastroenterology (2011) 1.85
Expression of lymphocytes and lymphocyte subsets in patients with severe acute respiratory syndrome. Clin Infect Dis (2003) 1.84
AMPK dysregulation promotes diabetes-related reduction of superoxide and mitochondrial function. J Clin Invest (2013) 1.84
Bionanotechnology based on silica nanoparticles. Med Res Rev (2004) 1.81
Role of RhoA-specific guanine exchange factors in regulation of endomitosis in megakaryocytes. Dev Cell (2012) 1.76