Published in Arthritis Rheum on October 01, 2008
Monophosphorylation of CD79a and CD79b ITAM motifs initiates a SHIP-1 phosphatase-mediated inhibitory signaling cascade required for B cell anergy. Immunity (2011) 1.27
Molecular underpinning of B-cell anergy. Immunol Rev (2010) 1.20
Immune semaphorins: novel features of neural guidance molecules. J Clin Immunol (2008) 1.04
Expansion of autoreactive unresponsive CD21-/low B cells in Sjögren's syndrome-associated lymphoproliferation. Arthritis Rheum (2013) 0.97
CD72, a coreceptor with both positive and negative effects on B lymphocyte development and function. J Clin Immunol (2008) 0.84
Distinct Transcriptomic Features are Associated with Transitional and Mature B-Cell Populations in the Mouse Spleen. Front Immunol (2015) 0.81
Chronic resveratrol intake reverses pro-inflammatory cytokine profile and oxidative DNA damage in ageing hybrid mice. Age (Dordr) (2010) 0.79
Altered cell-cell and cell-matrix interactions in the development of systemic autoimmunity. Autoimmunity (2009) 0.76
CD22 and CD72 are inhibitory receptors dominantly expressed in B lymphocytes and regulate systemic autoimmune diseases : English version. Z Rheumatol (2016) 0.76
CD72 negatively regulates B lymphocyte responses to the lupus-related endogenous toll-like receptor 7 ligand Sm/RNP. J Exp Med (2016) 0.75
Intracellular B Lymphocyte Signalling and the Regulation of Humoral Immunity and Autoimmunity. Clin Rev Allergy Immunol (2017) 0.75
[CD22 and CD72 are inhibitory receptors dominantly expressed in B lymphocytes and regulate systemic autoimmune diseases. German version]. Z Rheumatol (2016) 0.75
Predominant autoantibody production by early human B cell precursors. Science (2003) 13.14
Differential activation of transcription factors induced by Ca2+ response amplitude and duration. Nature (1997) 9.99
Altered immunoglobulin expression and functional silencing of self-reactive B lymphocytes in transgenic mice. Nature (1988) 9.17
Receptor editing in self-reactive bone marrow B cells. J Exp Med (1993) 5.49
Autoantigen microarrays for multiplex characterization of autoantibody responses. Nat Med (2002) 4.54
Negative regulation of lymphocyte activation and autoimmunity by the molecular adaptor Cbl-b. Nature (2000) 4.08
Cbl-b regulates the CD28 dependence of T-cell activation. Nature (2000) 3.89
B cell antigen receptor signaling 101. Mol Immunol (2004) 3.58
Regulation of B-cell fate by antigen-receptor signals. Nat Rev Immunol (2002) 3.27
B lymphocytes may escape tolerance by revising their antigen receptors. J Exp Med (1993) 2.78
Different nuclear signals are activated by the B cell receptor during positive versus negative signaling. Immunity (1997) 2.34
Identification of CD72 as a lymphocyte receptor for the class IV semaphorin CD100: a novel mechanism for regulating B cell signaling. Immunity (2000) 2.16
Clonal anergy: persistence in tolerant mice of antigen-binding B lymphocytes incapable of responding to antigen or mitogen. Proc Natl Acad Sci U S A (1980) 2.04
An inactivating point mutation in the inhibitory wedge of CD45 causes lymphoproliferation and autoimmunity. Cell (2000) 2.00
The class IV semaphorin CD100 plays nonredundant roles in the immune system: defective B and T cell activation in CD100-deficient mice. Immunity (2000) 1.96
The inhibitory Fcgamma receptor modulates autoimmunity by limiting the accumulation of immunoglobulin G+ anti-DNA plasma cells. Nat Immunol (2004) 1.95
TCR affinity and negative regulation limit autoimmunity. Nat Med (2004) 1.94
Protein kinase Cdelta controls self-antigen-induced B-cell tolerance. Nature (2002) 1.84
Deficiency in CD22, a B cell-specific inhibitory receptor, is sufficient to predispose to development of high affinity autoantibodies. J Exp Med (1999) 1.83
The calcineurin phosphatase complex modulates immunogenic B cell responses. Immunity (2006) 1.83
Restoration of tolerance in lupus by targeted inhibitory receptor expression. Science (2005) 1.81
Clonal deletion of autoreactive B lymphocytes in bone marrow chimeras. Proc Natl Acad Sci U S A (1989) 1.75
Systemic lupus erythematosus: multiple immunological phenotypes in a complex genetic disease. Adv Immunol (2006) 1.69
Spontaneous autoimmunity in 129 and C57BL/6 mice-implications for autoimmunity described in gene-targeted mice. PLoS Biol (2004) 1.68
Cblb is a major susceptibility gene for rat type 1 diabetes mellitus. Nat Genet (2002) 1.63
Activation of natural killer T cells in NZB/W mice induces Th1-type immune responses exacerbating lupus. J Clin Invest (2003) 1.55
How self-tolerance and the immunosuppressive drug FK506 prevent B-cell mitogenesis. Nature (2000) 1.50
The non-receptor tyrosine kinase Syk is a target of Cbl-mediated ubiquitylation upon B-cell receptor stimulation. EMBO J (2001) 1.43
CD5 maintains tolerance in anergic B cells. J Exp Med (2000) 1.42
Immunoglobulin M and D antigen receptors are both capable of mediating B lymphocyte activation, deletion, or anergy after interaction with specific antigen. J Exp Med (1992) 1.33
Scaffolding of antigen receptors for immunogenic versus tolerogenic signaling. Nat Immunol (2003) 1.30
Regulation and function of cyclin D2 in B lymphocyte subsets. J Immunol (2004) 1.25
Cbl-b negatively regulates B cell antigen receptor signaling in mature B cells through ubiquitination of the tyrosine kinase Syk. J Exp Med (2003) 1.25
CD72-deficient mice reveal nonredundant roles of CD72 in B cell development and activation. Immunity (1999) 1.23
B-cell targeted therapies in rheumatoid arthritis and systemic lupus erythematosus. Nat Clin Pract Rheumatol (2006) 1.17
Control of the B cell-intrinsic tolerance programs by ubiquitin ligases Cbl and Cbl-b. Immunity (2007) 1.06
SHP-1 requires inhibitory co-receptors to down-modulate B cell antigen receptor-mediated phosphorylation of cellular substrates. J Biol Chem (2001) 1.01
Susceptibility genes in the pathogenesis of murine lupus. Arthritis Res (2002) 1.00
The B-cell transmembrane protein CD72 binds to and is an in vivo substrate of the protein tyrosine phosphatase SHP-1. Curr Biol (1998) 0.99
Inhibitory coreceptors activated by antigens but not by anti-Ig heavy chain antibodies install requirement of costimulation through CD40 for survival and proliferation of B cells. J Immunol (2003) 0.95
Requirement for CD100-CD72 interactions in fine-tuning of B-cell antigen receptor signaling and homeostatic maintenance of the B-cell compartment. Int Immunol (2005) 0.89
CD72 down-modulates BCR-induced signal transduction and diminishes survival in primary mature B lymphocytes. J Immunol (2006) 0.86
CD72 polymorphisms associated with alternative splicing modify susceptibility to human systemic lupus erythematosus through epistatic interaction with FCGR2B. Hum Mol Genet (2004) 0.84
Positive signaling through CD72 induces mitogen-activated protein kinase activation and synergizes with B cell receptor signals to induce X-linked immunodeficiency B cell proliferation. J Immunol (2001) 0.84
Increased mutations of CD72 transcript in B-lymphocytes from adolescent patients with systemic lupus erythematosus. Pediatr Allergy Immunol (2006) 0.83
Down-regulation of CD72 and increased surface IgG on B cells in patients with lupus nephritis. Autoimmunity (2007) 0.77
Targeted deletion reveals essential and overlapping functions of the miR-17 through 92 family of miRNA clusters. Cell (2008) 12.29
Fatality in mice due to oversaturation of cellular microRNA/short hairpin RNA pathways. Nature (2006) 10.95
Chromatin remodelling during development. Nature (2010) 5.86
MicroRNA-mediated conversion of human fibroblasts to neurons. Nature (2011) 5.59
An essential switch in subunit composition of a chromatin remodeling complex during neural development. Neuron (2007) 5.35
Medulloblastoma exome sequencing uncovers subtype-specific somatic mutations. Nature (2012) 5.23
ATP-dependent chromatin remodeling: genetics, genomics and mechanisms. Cell Res (2011) 4.91
NFAT dysregulation by increased dosage of DSCR1 and DYRK1A on chromosome 21. Nature (2006) 4.80
Essential requirement for Wnt signaling in proliferation of adult small intestine and colon revealed by adenoviral expression of Dickkopf-1. Proc Natl Acad Sci U S A (2003) 4.76
Noncovalent functionalization of carbon nanotubes for highly specific electronic biosensors. Proc Natl Acad Sci U S A (2003) 4.57
Autoantigen microarrays for multiplex characterization of autoantibody responses. Nat Med (2002) 4.54
A pilot toxicology study of single-walled carbon nanotubes in a small sample of mice. Nat Nanotechnol (2008) 4.43
RAG2 PHD finger couples histone H3 lysine 4 trimethylation with V(D)J recombination. Nature (2007) 4.35
An embryonic stem cell chromatin remodeling complex, esBAF, is an essential component of the core pluripotency transcriptional network. Proc Natl Acad Sci U S A (2009) 4.07
An embryonic stem cell chromatin remodeling complex, esBAF, is essential for embryonic stem cell self-renewal and pluripotency. Proc Natl Acad Sci U S A (2009) 3.82
Immune inhibitory molecules LAG-3 and PD-1 synergistically regulate T-cell function to promote tumoral immune escape. Cancer Res (2011) 3.81
Dynamics and memory of heterochromatin in living cells. Cell (2012) 3.75
A field of myocardial-endocardial NFAT signaling underlies heart valve morphogenesis. Cell (2004) 3.71
Understanding the words of chromatin regulation. Cell (2009) 3.67
MicroRNA-mediated switching of chromatin-remodelling complexes in neural development. Nature (2009) 3.66
Proteomic and bioinformatic analysis of mammalian SWI/SNF complexes identifies extensive roles in human malignancy. Nat Genet (2013) 3.51
Treating metastatic cancer with nanotechnology. Nat Rev Cancer (2011) 3.30
Genomic expression programs and the integration of the CD28 costimulatory signal in T cell activation. Proc Natl Acad Sci U S A (2002) 3.28
Proteome-wide analysis in Saccharomyces cerevisiae identifies several PHD fingers as novel direct and selective binding modules of histone H3 methylated at either lysine 4 or lysine 36. J Biol Chem (2006) 3.14
Stage-specific sensitivity to p53 restoration during lung cancer progression. Nature (2010) 3.03
Calcineurin/NFAT signalling regulates pancreatic beta-cell growth and function. Nature (2006) 2.96
Regulation of dendritic development by neuron-specific chromatin remodeling complexes. Neuron (2007) 2.89
Protein microarrays guide tolerizing DNA vaccine treatment of autoimmune encephalomyelitis. Nat Biotechnol (2003) 2.80
Nuclear actin and actin-related proteins in chromatin remodeling. Annu Rev Biochem (2001) 2.74
Sequential roles of Brg, the ATPase subunit of BAF chromatin remodeling complexes, in thymocyte development. Immunity (2003) 2.56
Neurotrophins and netrins require calcineurin/NFAT signaling to stimulate outgrowth of embryonic axons. Cell (2003) 2.54
Effects of an anti-TSLP antibody on allergen-induced asthmatic responses. N Engl J Med (2014) 2.53
Retracted CD4+ T cell autoimmunity to hypocretin/orexin and cross-reactivity to a 2009 H1N1 influenza A epitope in narcolepsy. Sci Transl Med (2013) 2.51
From neural development to cognition: unexpected roles for chromatin. Nat Rev Genet (2013) 2.42
Reciprocal regulation of CD4/CD8 expression by SWI/SNF-like BAF complexes. Nature (2002) 2.41
Scalable signaling mediated by T cell antigen receptor-CD3 ITAMs ensures effective negative selection and prevents autoimmunity. Nat Immunol (2008) 2.34
Antigen microarray profiling of autoantibodies in rheumatoid arthritis. Arthritis Rheum (2005) 2.30
Renaming the DSCR1/Adapt78 gene family as RCAN: regulators of calcineurin. FASEB J (2007) 2.30
Nuclear factor I/B is an oncogene in small cell lung cancer. Genes Dev (2011) 2.29
esBAF facilitates pluripotency by conditioning the genome for LIF/STAT3 signalling and by regulating polycomb function. Nat Cell Biol (2011) 2.29
Notch signals positively regulate activity of the mTOR pathway in T-cell acute lymphoblastic leukemia. Blood (2007) 2.29
Integration of Notch 1 and calcineurin/NFAT signaling pathways in keratinocyte growth and differentiation control. Dev Cell (2005) 2.21
Conditional protein alleles using knockin mice and a chemical inducer of dimerization. Mol Cell (2003) 2.20
Calcineurin B1 is essential for positive but not negative selection during thymocyte development. Immunity (2004) 2.20
Harnessing chaperones to generate small-molecule inhibitors of amyloid beta aggregation. Science (2004) 2.14
Pathway-based identification of biomarkers for targeted therapeutics: personalized oncology with PI3K pathway inhibitors. Sci Transl Med (2010) 2.13
Selective tyrosine kinase inhibition by imatinib mesylate for the treatment of autoimmune arthritis. J Clin Invest (2006) 2.10
Protein microarrays with carbon nanotubes as multicolor Raman labels. Nat Biotechnol (2008) 2.08
Lysine methylation of the NF-κB subunit RelA by SETD6 couples activity of the histone methyltransferase GLP at chromatin to tonic repression of NF-κB signaling. Nat Immunol (2010) 2.07
Reversible disruption of mSWI/SNF (BAF) complexes by the SS18-SSX oncogenic fusion in synovial sarcoma. Cell (2013) 2.05
Lymphocyte calcium signaling from membrane to nucleus. Nat Immunol (2006) 2.03
Dynamic changes in transcription factor complexes during erythroid differentiation revealed by quantitative proteomics. Nat Struct Mol Biol (2003) 2.00
Calcium signalling in lymphocytes. Curr Opin Immunol (2003) 2.00
Regulation of human Th9 differentiation by type I interferons and IL-21. Immunol Cell Biol (2010) 1.99
NFAT signaling and the invention of vertebrates. Trends Cell Biol (2007) 1.98
The ubiquitin modifying enzyme A20 restricts B cell survival and prevents autoimmunity. Immunity (2010) 1.97
Calcineurin is required in urinary tract mesenchyme for the development of the pyeloureteral peristaltic machinery. J Clin Invest (2004) 1.95
Calcineurin/NFAT signaling in osteoblasts regulates bone mass. Dev Cell (2006) 1.95
Protein microarrays for multiplex analysis of signal transduction pathways. Nat Med (2004) 1.89
Endogenous T cell responses to antigens expressed in lung adenocarcinomas delay malignant tumor progression. Cancer Cell (2011) 1.89
Induction of antigen-specific tolerance in multiple sclerosis after immunization with DNA encoding myelin basic protein in a randomized, placebo-controlled phase 1/2 trial. Arch Neurol (2007) 1.86
The calcineurin phosphatase complex modulates immunogenic B cell responses. Immunity (2006) 1.83
Chemical rescue of cleft palate and midline defects in conditional GSK-3beta mice. Nature (2007) 1.83
Genetic loss of calcineurin blocks mechanical overload-induced skeletal muscle fiber type switching but not hypertrophy. J Biol Chem (2004) 1.82
Identification of a polymorphic, neuron-specific chromatin remodeling complex. Genes Dev (2002) 1.80
Calcineurin/NFAT signaling is required for neuregulin-regulated Schwann cell differentiation. Science (2009) 1.76
Apoptosis and other immune biomarkers predict influenza vaccine responsiveness. Mol Syst Biol (2013) 1.75
Achieving stability through editing and chaperoning: regulation of MHC class II peptide binding and expression. Immunol Rev (2005) 1.74
Characterizing deformability and surface friction of cancer cells. Proc Natl Acad Sci U S A (2013) 1.72
Neonatal β cell development in mice and humans is regulated by calcineurin/NFAT. Dev Cell (2012) 1.72
Selective killing of K-ras mutant cancer cells by small molecule inducers of oxidative stress. Proc Natl Acad Sci U S A (2011) 1.68
The gene encoding early growth response 2, a target of the transcription factor NFAT, is required for the development and maturation of natural killer T cells. Nat Immunol (2009) 1.66
Calcineurin: a central controller of signalling in eukaryotes. EMBO Rep (2004) 1.65
Rapamycin analogs with differential binding specificity permit orthogonal control of protein activity. Chem Biol (2006) 1.65
Precarious balance: Th17 cells in host defense. Infect Immun (2009) 1.60
ATP-dependent chromatin remodeling in neural development. Curr Opin Neurobiol (2009) 1.58
Generalized resistance to thymic deletion in the NOD mouse; a polygenic trait characterized by defective induction of Bim. Immunity (2004) 1.57
Phosphatidylinositol-dependent actin filament binding by the SWI/SNF-like BAF chromatin remodeling complex. Proc Natl Acad Sci U S A (2002) 1.57
Chaperone activity of α B-crystallin is responsible for its incorrect assignment as an autoantigen in multiple sclerosis. J Immunol (2011) 1.56
IRF9 and STAT1 are required for IgG autoantibody production and B cell expression of TLR7 in mice. J Clin Invest (2008) 1.55
BAF complexes facilitate decatenation of DNA by topoisomerase IIα. Nature (2013) 1.52
Chromatin regulatory mechanisms in pluripotency. Annu Rev Cell Dev Biol (2010) 1.51
T cell-mediated autoimmune disease due to low-affinity crossreactivity to common microbial peptides. Immunity (2009) 1.50
Specific post-translational histone modifications of neutrophil extracellular traps as immunogens and potential targets of lupus autoantibodies. Arthritis Res Ther (2012) 1.49
A combinatorial extracellular matrix platform identifies cell-extracellular matrix interactions that correlate with metastasis. Nat Commun (2012) 1.47
Response and resistance to NF-κB inhibitors in mouse models of lung adenocarcinoma. Cancer Discov (2011) 1.46
Cytomegalovirus viremia during Campath-1H therapy for relapsed and refractory chronic lymphocytic leukemia and prolymphocytic leukemia. Clin Lymphoma (2002) 1.45
Susceptibility of immature and mature Langerhans cell-type dendritic cells to infection and immunomodulation by human cytomegalovirus. J Virol (2003) 1.44
MicroRNAs: regulators of neuronal fate. Curr Opin Cell Biol (2013) 1.43
Phase 2 trial of a DNA vaccine encoding myelin basic protein for multiple sclerosis. Ann Neurol (2008) 1.43
Interaction of HLA-DR with an acidic face of HLA-DM disrupts sequence-dependent interactions with peptides. Immunity (2003) 1.43
CD8+ recent thymic emigrants home to and efficiently repopulate the small intestine epithelium. Nat Immunol (2006) 1.42
Identification of a putative regulator of early T cell activation genes. Science. 1988. 241: 202-205. J Immunol (2010) 1.41
Over-expression of CKS1B activates both MEK/ERK and JAK/STAT3 signaling pathways and promotes myeloma cell drug-resistance. Oncotarget (2010) 1.40
Role of pediatric and internist rheumatologists in treating children with rheumatic diseases. Pediatrics (2004) 1.39