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Control of the embryonic stem cell state. Cell (2011) 6.89

ATP-dependent chromatin remodeling: genetics, genomics and mechanisms. Cell Res (2011) 4.91

Cancer genetics and epigenetics: two sides of the same coin? Cancer Cell (2012) 3.65

Integrated genomic analyses identify ARID1A and ARID1B alterations in the childhood cancer neuroblastoma. Nat Genet (2012) 3.38

Combinatorial patterning of chromatin regulators uncovered by genome-wide location analysis in human cells. Cell (2011) 3.20

Immunogenetics. Chromatin state dynamics during blood formation. Science (2014) 2.99

Transcriptional regulation and its misregulation in disease. Cell (2013) 2.92

Chromatin regulation by Brg1 underlies heart muscle development and disease. Nature (2010) 2.85

ARID1A, a factor that promotes formation of SWI/SNF-mediated chromatin remodeling, is a tumor suppressor in gynecologic cancers. Cancer Res (2011) 2.71

Direct lineage conversions: unnatural but useful? Nat Biotechnol (2011) 2.69

Trithorax group proteins: switching genes on and keeping them active. Nat Rev Mol Cell Biol (2011) 2.56

Repressive LTR nucleosome positioning by the BAF complex is required for HIV latency. PLoS Biol (2011) 2.49

From neural development to cognition: unexpected roles for chromatin. Nat Rev Genet (2013) 2.42

esBAF facilitates pluripotency by conditioning the genome for LIF/STAT3 signalling and by regulating polycomb function. Nat Cell Biol (2011) 2.29

Child health, developmental plasticity, and epigenetic programming. Endocr Rev (2010) 2.15

Epigenetic programming and reprogramming during development. Nat Struct Mol Biol (2013) 2.13

Transcriptional and epigenetic control of T helper cell specification: molecular mechanisms underlying commitment and plasticity. Annu Rev Immunol (2012) 2.06

Mutation and loss of expression of ARID1A in uterine low-grade endometrioid carcinoma. Am J Surg Pathol (2011) 2.03

Foxa2 and H2A.Z mediate nucleosome depletion during embryonic stem cell differentiation. Cell (2012) 2.02

Operating on chromatin, a colorful language where context matters. J Mol Biol (2011) 2.00

Chromatin modifiers and remodellers: regulators of cellular differentiation. Nat Rev Genet (2013) 1.98

Harnessing of the nucleosome-remodeling-deacetylase complex controls lymphocyte development and prevents leukemogenesis. Nat Immunol (2011) 1.89

Targeted disruption of the EZH2-EED complex inhibits EZH2-dependent cancer. Nat Chem Biol (2013) 1.75

Molecular roadblocks for cellular reprogramming. Mol Cell (2012) 1.74

Epigenetic mechanisms in neurological disease. Nat Med (2012) 1.74

Chromatin remodelling complex dosage modulates transcription factor function in heart development. Nat Commun (2011) 1.69

Dynamic epigenetic regulation in neurons: enzymes, stimuli and signaling pathways. Nat Neurosci (2010) 1.68

Nuclear actin polymerization is required for transcriptional reprogramming of Oct4 by oocytes. Genes Dev (2011) 1.67

Regulation of primary response genes. Mol Cell (2011) 1.56

A SWI/SNF-related autism syndrome caused by de novo mutations in ADNP. Nat Genet (2014) 1.55

OCT4 establishes and maintains nucleosome-depleted regions that provide additional layers of epigenetic regulation of its target genes. Proc Natl Acad Sci U S A (2011) 1.51

Epigenetics: A New Bridge between Nutrition and Health. Adv Nutr (2010) 1.51

Remodeling of three-dimensional organization of the nucleus during terminal keratinocyte differentiation in the epidermis. J Invest Dermatol (2013) 1.51

Bivalent histone modifications in early embryogenesis. Curr Opin Cell Biol (2012) 1.48

Epigenome mapping in normal and disease States. Circ Res (2010) 1.47

Vascular smooth muscle progenitor cells: building and repairing blood vessels. Circ Res (2011) 1.46

Chromatin remodeling inactivates activity genes and regulates neural coding. Science (2016) 1.44

Clinicopathological significance of loss of ARID1A immunoreactivity in ovarian clear cell carcinoma. Int J Mol Sci (2010) 1.44

Histone variants in metazoan development. Dev Cell (2010) 1.42

ChAP-MS: a method for identification of proteins and histone posttranslational modifications at a single genomic locus. Cell Rep (2012) 1.42

A chemical probe toolbox for dissecting the cancer epigenome. Nat Rev Cancer (2017) 1.40

Regulation of transcription in plants: mechanisms controlling developmental switches. Nat Rev Genet (2010) 1.38

Master regulators or lineage-specifying? Changing views on CD4+ T cell transcription factors. Nat Rev Immunol (2012) 1.36

Chromatin remodeling in cardiovascular development and physiology. Circ Res (2011) 1.34

Histone regulation in the CNS: basic principles of epigenetic plasticity. Neuropsychopharmacology (2012) 1.33

Setdb1 histone methyltransferase regulates mood-related behaviors and expression of the NMDA receptor subunit NR2B. J Neurosci (2010) 1.33

Epigenetic regulation of gene expression in keratinocytes. J Invest Dermatol (2012) 1.32

Gene expression of pluripotency determinants is conserved between mammalian and planarian stem cells. EMBO J (2012) 1.31

Adult neural stem cells stake their ground. Trends Neurosci (2014) 1.30

Regulating the chromatin landscape: structural and mechanistic perspectives. Annu Rev Biochem (2014) 1.29

The CHD3 remodeler PICKLE associates with genes enriched for trimethylation of histone H3 lysine 27. Plant Physiol (2012) 1.27

Arabidopsis HDA6 regulates locus-directed heterochromatin silencing in cooperation with MET1. PLoS Genet (2011) 1.27

SWI/SNF chromatin-remodeling factors: multiscale analyses and diverse functions. J Biol Chem (2012) 1.24

Alterations in cardiac DNA methylation in human dilated cardiomyopathy. EMBO Mol Med (2013) 1.23

The transcription factor Pax5 regulates its target genes by recruiting chromatin-modifying proteins in committed B cells. EMBO J (2011) 1.22

The chromatin-remodeling enzyme BRG1 modulates vascular Wnt signaling at two levels. Proc Natl Acad Sci U S A (2011) 1.21

The emerging roles of ARID1A in tumor suppression. Cancer Biol Ther (2014) 1.21

Protein networks as logic functions in development and cancer. PLoS Comput Biol (2011) 1.19

Remodelers organize cellular chromatin by counteracting intrinsic histone-DNA sequence preferences in a class-specific manner. Mol Cell Biol (2011) 1.19

PIK3CA mutations and loss of ARID1A protein expression are early events in the development of cystic ovarian clear cell adenocarcinoma. Virchows Arch (2011) 1.19

Next-generation sequencing techniques for eukaryotic microorganisms: sequencing-based solutions to biological problems. Eukaryot Cell (2010) 1.18

Early cardiac development: a view from stem cells to embryos. Cardiovasc Res (2012) 1.18

Dynamic BRG1 recruitment during T helper differentiation and activation reveals distal regulatory elements. Mol Cell Biol (2011) 1.17

Differential roles for MBD2 and MBD3 at methylated CpG islands, active promoters and binding to exon sequences. Nucleic Acids Res (2013) 1.16

Epigenetic factors influencing resistance to nuclear reprogramming. Trends Genet (2011) 1.14

Diversity of operation in ATP-dependent chromatin remodelers. Biochim Biophys Acta (2011) 1.14

Stem cells and reprogramming: breaking the epigenetic barrier? Trends Pharmacol Sci (2011) 1.12

Embryonic stem cell and induced pluripotent stem cell: an epigenetic perspective. Cell Res (2012) 1.12

Corepressor for element-1-silencing transcription factor preferentially mediates gene networks underlying neural stem cell fate decisions. Proc Natl Acad Sci U S A (2010) 1.12

CHD5, a brain-specific paralog of Mi2 chromatin remodeling enzymes, regulates expression of neuronal genes. PLoS One (2011) 1.11

Genetic syndromes caused by mutations in epigenetic genes. Hum Genet (2013) 1.11

MicroRNAs in Neural Stem Cells and Neurogenesis. Front Neurosci (2012) 1.10

The cell biology of disease: FSHD: copy number variations on the theme of muscular dystrophy. J Cell Biol (2010) 1.10

Rsf-1, a chromatin remodeling protein, induces DNA damage and promotes genomic instability. J Biol Chem (2010) 1.10

The histone modifications governing TFF1 transcription mediated by estrogen receptor. J Biol Chem (2011) 1.10

Chromatin remodeling enzyme Brg1 is required for mouse lens fiber cell terminal differentiation and its denucleation. Epigenetics Chromatin (2010) 1.10

Arabidopsis chromatin remodeling factor PICKLE interacts with transcription factor HY5 to regulate hypocotyl cell elongation. Plant Cell (2013) 1.08

Regulation of leaf maturation by chromatin-mediated modulation of cytokinin responses. Dev Cell (2013) 1.07

Nucleosome remodeling and epigenetics. Cold Spring Harb Perspect Biol (2013) 1.07

Functional redundancy of SWI/SNF catalytic subunits in maintaining vascular endothelial cells in the adult heart. Circ Res (2012) 1.06

Genomic approaches to deconstruct pluripotency. Annu Rev Genomics Hum Genet (2011) 1.06

EYA1 and SIX1 drive the neuronal developmental program in cooperation with the SWI/SNF chromatin-remodeling complex and SOX2 in the mammalian inner ear. Development (2012) 1.06

Chromatin as an oxygen sensor and active player in the hypoxia response. Cell Signal (2011) 1.05

Insights into interphase large-scale chromatin structure from analysis of engineered chromosome regions. Cold Spring Harb Symp Quant Biol (2011) 1.05

Chromatin remodeling complex NURF regulates thymocyte maturation. Genes Dev (2011) 1.05

Epigenetic virtues of chromodomains. Crit Rev Biochem Mol Biol (2011) 1.03

Quantitative analysis of the chromatin proteome in disease reveals remodeling principles and identifies high mobility group protein B2 as a regulator of hypertrophic growth. Mol Cell Proteomics (2012) 1.03

A key role for Chd1 in histone H3 dynamics at the 3' ends of long genes in yeast. PLoS Genet (2012) 1.02

Endocervical-type mucinous borderline tumors are related to endometrioid tumors based on mutation and loss of expression of ARID1A. Int J Gynecol Pathol (2012) 1.02

Structure, function and regulation of CSB: a multi-talented gymnast. Mech Ageing Dev (2013) 1.02

Reproductive dysfunction and decreased GnRH neurogenesis in a mouse model of CHARGE syndrome. Hum Mol Genet (2011) 1.02

The H3K4-Methyl Epigenome Regulates Leukemia Stem Cell Oncogenic Potential. Cancer Cell (2015) 1.02

Functionally distinct Gata3/Chd4 complexes coordinately establish T helper 2 (Th2) cell identity. Proc Natl Acad Sci U S A (2013) 1.01

The chromatin remodeling factor Bap55 functions through the TIP60 complex to regulate olfactory projection neuron dendrite targeting. Neural Dev (2011) 1.01

SWI/SNF protein component BAF250a regulates cardiac progenitor cell differentiation by modulating chromatin accessibility during second heart field development. J Biol Chem (2012) 1.01

Post-translational modifications of histones that influence nucleosome dynamics. Chem Rev (2014) 0.99

Epigenetic regulation of skin: focus on the Polycomb complex. Cell Mol Life Sci (2012) 0.99

BRG1 is a prognostic marker and potential therapeutic target in human breast cancer. PLoS One (2013) 0.98

Epigenetic factors and cardiac development. Cardiovasc Res (2011) 0.97

Capturing chromosome conformation. Science (2002) 23.93

DNA methylation landscapes: provocative insights from epigenomics. Nat Rev Genet (2008) 15.45

Stem cells, the molecular circuitry of pluripotency and nuclear reprogramming. Cell (2008) 14.17

Chromatin structure: a repeating unit of histones and DNA. Science (1974) 13.18

ATP-driven exchange of histone H2AZ variant catalyzed by SWR1 chromatin remodeling complex. Science (2003) 10.04

Hyperdynamic plasticity of chromatin proteins in pluripotent embryonic stem cells. Dev Cell (2006) 8.53

The dermatomyositis-specific autoantigen Mi2 is a component of a complex containing histone deacetylase and nucleosome remodeling activities. Cell (1998) 7.37

Stimulation of GAL4 derivative binding to nucleosomal DNA by the yeast SWI/SNF complex. Science (1994) 7.17

Stabilization of chromatin structure by PRC1, a Polycomb complex. Cell (1999) 6.90

Mutations in a new member of the chromodomain gene family cause CHARGE syndrome. Nat Genet (2004) 6.90

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Dynamic genome architecture in the nuclear space: regulation of gene expression in three dimensions. Nat Rev Genet (2007) 6.14

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Recognition of trimethylated histone H3 lysine 4 facilitates the recruitment of transcription postinitiation factors and pre-mRNA splicing. Mol Cell (2007) 5.78

The NuRD component Mbd3 is required for pluripotency of embryonic stem cells. Nat Cell Biol (2006) 5.74

Double chromodomains cooperate to recognize the methylated histone H3 tail. Nature (2005) 5.53

An essential switch in subunit composition of a chromatin remodeling complex during neural development. Neuron (2007) 5.35

CHD5 is a tumor suppressor at human 1p36. Cell (2007) 4.90

Genome-wide approaches to studying chromatin modifications. Nat Rev Genet (2008) 4.28

An RNAi screen of chromatin proteins identifies Tip60-p400 as a regulator of embryonic stem cell identity. Cell (2008) 4.27

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Chd1 regulates open chromatin and pluripotency of embryonic stem cells. Nature (2009) 4.13

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H2AZ is enriched at polycomb complex target genes in ES cells and is necessary for lineage commitment. Cell (2008) 3.90

Bmi1 regulates mitochondrial function and the DNA damage response pathway. Nature (2009) 3.90

An embryonic stem cell chromatin remodeling complex, esBAF, is essential for embryonic stem cell self-renewal and pluripotency. Proc Natl Acad Sci U S A (2009) 3.82

The human Mi-2/NuRD complex and gene regulation. Oncogene (2007) 3.76

Directed transdifferentiation of mouse mesoderm to heart tissue by defined factors. Nature (2009) 3.70

Understanding the words of chromatin regulation. Cell (2009) 3.67

MicroRNA-mediated switching of chromatin-remodelling complexes in neural development. Nature (2009) 3.66

The ISWI chromatin-remodeling protein is required for gene expression and the maintenance of higher order chromatin structure in vivo. Mol Cell (2000) 3.62

The murine SNF5/INI1 chromatin remodeling factor is essential for embryonic development and tumor suppression. EMBO Rep (2000) 3.30

ES cell pluripotency and germ-layer formation require the SWI/SNF chromatin remodeling component BAF250a. Proc Natl Acad Sci U S A (2008) 3.15

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Chromatin remodelling factor Mll1 is essential for neurogenesis from postnatal neural stem cells. Nature (2009) 2.87

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Mammalian SWI/SNF complexes promote MyoD-mediated muscle differentiation. Nat Genet (2001) 2.71

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The Drosophila snr1 and brm proteins are related to yeast SWI/SNF proteins and are components of a large protein complex. Mol Biol Cell (1995) 2.67

Rnf2 (Ring1b) deficiency causes gastrulation arrest and cell cycle inhibition. Proc Natl Acad Sci U S A (2003) 2.67

NoRC--a novel member of mammalian ISWI-containing chromatin remodeling machines. EMBO J (2001) 2.67

Sequential roles of Brg, the ATPase subunit of BAF chromatin remodeling complexes, in thymocyte development. Immunity (2003) 2.56

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Genome-wide analyses identify transcription factors required for proper morphogenesis of Drosophila sensory neuron dendrites. Genes Dev (2006) 2.49

The MeCP1 complex represses transcription through preferential binding, remodeling, and deacetylating methylated nucleosomes. Genes Dev (2001) 2.48

Reciprocal regulation of CD4/CD8 expression by SWI/SNF-like BAF complexes. Nature (2002) 2.41

Biological functions of the ISWI chromatin remodeling complex NURF. Genes Dev (2002) 2.37

SWI/SNF-Brg1 regulates self-renewal and occupies core pluripotency-related genes in embryonic stem cells. Stem Cells (2009) 2.33

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Mbd3, a component of the NuRD co-repressor complex, is required for development of pluripotent cells. Development (2007) 2.23

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The BRG1 transcriptional coregulator. Nucl Recept Signal (2008) 2.00

Cooperation between C/EBPalpha TBP/TFIIB and SWI/SNF recruiting domains is required for adipocyte differentiation. Genes Dev (2001) 2.00

Regulation of muscle development by DPF3, a novel histone acetylation and methylation reader of the BAF chromatin remodeling complex. Genes Dev (2008) 1.96

The chromatin remodeling protein, SRCAP, is critical for deposition of the histone variant H2A.Z at promoters. J Biol Chem (2007) 1.96

Polybromo protein BAF180 functions in mammalian cardiac chamber maturation. Genes Dev (2004) 1.93

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The ISWI ATPase Snf2h is required for early mouse development. Proc Natl Acad Sci U S A (2003) 1.82

ISWI regulates higher-order chromatin structure and histone H1 assembly in vivo. PLoS Biol (2007) 1.82

Purification of a human SRCAP complex that remodels chromatin by incorporating the histone variant H2A.Z into nucleosomes. Biochemistry (2006) 1.81

A Brg1 mutation that uncouples ATPase activity from chromatin remodeling reveals an essential role for SWI/SNF-related complexes in beta-globin expression and erythroid development. Genes Dev (2005) 1.81

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BRD7, a novel PBAF-specific SWI/SNF subunit, is required for target gene activation and repression in embryonic stem cells. J Biol Chem (2008) 1.80

The Drosophila BRM complex facilitates global transcription by RNA polymerase II. EMBO J (2002) 1.78

Drosophila Kismet regulates histone H3 lysine 27 methylation and early elongation by RNA polymerase II. PLoS Genet (2008) 1.75

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Smarcc1/Baf155 couples self-renewal gene repression with changes in chromatin structure in mouse embryonic stem cells. Stem Cells (2009) 1.72

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Loss of Chd7 function in gene-trapped reporter mice is embryonic lethal and associated with severe defects in multiple developing tissues. Mamm Genome (2007) 1.58

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CECR2, a protein involved in neurulation, forms a novel chromatin remodeling complex with SNF2L. Hum Mol Genet (2005) 1.35

INO80 subfamily of chromatin remodeling complexes. Mutat Res (2007) 1.29

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Defects in neural stem cell proliferation and olfaction in Chd7 deficient mice indicate a mechanism for hyposmia in human CHARGE syndrome. Hum Mol Genet (2009) 1.26

The transcriptional coactivator SAYP is a trithorax group signature subunit of the PBAP chromatin remodeling complex. Mol Cell Biol (2008) 1.23

Mutation of the SNF2 family member Chd2 affects mouse development and survival. J Cell Physiol (2006) 1.23

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Drosophila ISWI regulates the association of histone H1 with interphase chromosomes in vivo. Genetics (2009) 1.16

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Investigations of CHD1 function in transcription and development of Drosophila melanogaster. Genetics (2008) 1.06

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MicroRNA-mediated switching of chromatin-remodelling complexes in neural development. Nature (2009) 3.66

Proteomic and bioinformatic analysis of mammalian SWI/SNF complexes identifies extensive roles in human malignancy. Nat Genet (2013) 3.51

Genomic expression programs and the integration of the CD28 costimulatory signal in T cell activation. Proc Natl Acad Sci U S A (2002) 3.28

Calcineurin/NFAT signalling regulates pancreatic beta-cell growth and function. Nature (2006) 2.96

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Neurotrophins and netrins require calcineurin/NFAT signaling to stimulate outgrowth of embryonic axons. Cell (2003) 2.54

From neural development to cognition: unexpected roles for chromatin. Nat Rev Genet (2013) 2.42

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Harnessing chaperones to generate small-molecule inhibitors of amyloid beta aggregation. Science (2004) 2.14

Reversible disruption of mSWI/SNF (BAF) complexes by the SS18-SSX oncogenic fusion in synovial sarcoma. Cell (2013) 2.05

Lymphocyte calcium signaling from membrane to nucleus. Nat Immunol (2006) 2.03

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Generalized resistance to thymic deletion in the NOD mouse; a polygenic trait characterized by defective induction of Bim. Immunity (2004) 1.57

Phosphatidylinositol-dependent actin filament binding by the SWI/SNF-like BAF chromatin remodeling complex. Proc Natl Acad Sci U S A (2002) 1.57

BAF complexes facilitate decatenation of DNA by topoisomerase IIα. Nature (2013) 1.52

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