Calcium plus vitamin D supplementation and the risk of breast cancer.

PubWeight™: 3.60‹?› | Rank: Top 1%

🔗 View Article (PMC 2673920)

Published in J Natl Cancer Inst on November 11, 2008

Authors

Rowan T Chlebowski1, Karen C Johnson, Charles Kooperberg, Mary Pettinger, Jean Wactawski-Wende, Tom Rohan, Jacques Rossouw, Dorothy Lane, Mary Jo O'Sullivan, Shagufta Yasmeen, Robert A Hiatt, James M Shikany, Mara Vitolins, Janu Khandekar, F Allan Hubbell, Women's Health Initiative Investigators

Author Affiliations

1: Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center, Torrance, CA 90502, USA. rchlebowski@gmail.com

Associated clinical trials:

Genetic, Dietary and Environmental Influences on Vitamin D Metabolism | NCT02590614

Articles citing this

(truncated to the top 100)

Health risks and benefits from calcium and vitamin D supplementation: Women's Health Initiative clinical trial and cohort study. Osteoporos Int (2012) 4.09

Vitamin D insufficiency. Mayo Clin Proc (2011) 2.89

Calcium plus vitamin D supplementation and health outcomes five years after active intervention ended: the Women's Health Initiative. J Womens Health (Larchmt) (2013) 2.81

The nonskeletal effects of vitamin D: an Endocrine Society scientific statement. Endocr Rev (2012) 2.71

Calcium and vitamin D supplements and health outcomes: a reanalysis of the Women's Health Initiative (WHI) limited-access data set. Am J Clin Nutr (2011) 2.44

Overview of the Cohort Consortium Vitamin D Pooling Project of Rarer Cancers. Am J Epidemiol (2010) 2.25

Vitamin D, disease and therapeutic opportunities. Nat Rev Drug Discov (2010) 2.02

The role of vitamin D in cancer prevention: does UV protection conflict with the need to raise low levels of vitamin D? Dtsch Arztebl Int (2010) 1.96

Predictors of serum 25-hydroxyvitamin D concentrations among postmenopausal women: the Women's Health Initiative Calcium plus Vitamin D clinical trial. Am J Clin Nutr (2010) 1.67

The influence of health and lifestyle characteristics on the relation of serum 25-hydroxyvitamin D with risk of colorectal and breast cancer in postmenopausal women. Am J Epidemiol (2012) 1.62

Dietary supplements and cancer prevention: balancing potential benefits against proven harms. J Natl Cancer Inst (2012) 1.60

Changing Incidence of Serum 25-Hydroxyvitamin D Values Above 50 ng/mL: A 10-Year Population-Based Study. Mayo Clin Proc (2015) 1.58

Adolescent intakes of vitamin D and calcium and incidence of proliferative benign breast disease. Breast Cancer Res Treat (2012) 1.46

Estrogen alone and joint symptoms in the Women's Health Initiative randomized trial. Menopause (2013) 1.42

Vitamin D levels and menopause-related symptoms. Menopause (2014) 1.41

Serum 25-hydroxyvitamin D concentrations and postmenopausal breast cancer risk: a nested case control study in the Cancer Prevention Study-II Nutrition Cohort. Breast Cancer Res (2009) 1.33

Effect of interval between serum draw and follow-up period on relative risk of cancer incidence with respect to 25-hydroxyvitamin D level: Implications for meta-analyses and setting vitamin D guidelines. Dermatoendocrinol (2011) 1.29

Vitamin D: The "sunshine" vitamin. J Pharmacol Pharmacother (2012) 1.24

Serum 25-hydroxyvitamin D concentrations in relation to cardiometabolic risk factors and metabolic syndrome in postmenopausal women. Am J Clin Nutr (2011) 1.22

The effect of calcium plus vitamin D on risk for invasive cancer: results of the Women's Health Initiative (WHI) calcium plus vitamin D randomized clinical trial. Nutr Cancer (2011) 1.20

Plasma vitamin D levels, menopause, and risk of breast cancer: dose-response meta-analysis of prospective studies. Medicine (Baltimore) (2013) 1.19

Variants in the vitamin D pathway, serum levels of vitamin D, and estrogen receptor negative breast cancer among African-American women: a case-control study. Breast Cancer Res (2012) 1.18

Exposure to oral bisphosphonates and risk of cancer. Int J Cancer (2012) 1.17

Vitamin D and breast cancer recurrence in the Women's Healthy Eating and Living (WHEL) Study. Am J Clin Nutr (2010) 1.12

Serum 25-hydroxyvitamin D and cancer mortality in the NHANES III study (1988-2006). Cancer Res (2010) 1.12

Vitamin D supplementation and depression in the women's health initiative calcium and vitamin D trial. Am J Epidemiol (2012) 1.10

Calcium plus vitamin D supplementation and the risk of nonmelanoma and melanoma skin cancer: post hoc analyses of the women's health initiative randomized controlled trial. J Clin Oncol (2011) 1.08

Vitamin D intake from foods and supplements and depressive symptoms in a diverse population of older women. Am J Clin Nutr (2011) 1.08

Vitamin D and the mammary gland: a review on its role in normal development and breast cancer. Breast Cancer Res (2012) 1.02

Plasma 25-hydroxyvitamin D and risk of breast cancer in the Nurses' Health Study II. Breast Cancer Res (2011) 1.01

A prospective study of serum 25-hydroxyvitamin D levels, blood pressure, and incident hypertension in postmenopausal women. Am J Epidemiol (2011) 0.99

Vitamin D receptor gene polymorphisms and prognosis of breast cancer among African-American and Hispanic women. PLoS One (2013) 0.98

The association between vitamin D receptor expression and prolonged overall survival in breast cancer. J Histochem Cytochem (2011) 0.97

Vitamin D intake, blood 25(OH)D levels, and breast cancer risk or mortality: a meta-analysis. Br J Cancer (2014) 0.97

Vitamin D and breast cancer. Oncologist (2012) 0.96

A randomized controlled trial of calcium plus vitamin D supplementation and risk of benign proliferative breast disease. Breast Cancer Res Treat (2008) 0.95

Circulating levels of 25-hydroxyvitamin D and risk of breast cancer: a nested case-control study. Breast Cancer Res (2013) 0.95

Vitamin D and breast cancer: interpreting current evidence. Breast Cancer Res (2011) 0.95

25-Hydroxy vitamin-D, obesity, and associated variables as predictors of breast cancer risk and tamoxifen benefit in NSABP-P1. Breast Cancer Res Treat (2012) 0.94

Redefining the impact of nutrition on breast cancer incidence: is epigenetics involved? Nutr Res Rev (2012) 0.93

Vitamin D and Colorectal, Breast, and Prostate Cancers: A Review of the Epidemiological Evidence. J Cancer (2016) 0.92

Vitamin D and the cardiovascular system. Osteoporos Int (2013) 0.92

Dietary vitamin D intake and serum 25-hydroxyvitamin D level in relation to disease outcomes in head and neck cancer patients. Int J Cancer (2010) 0.92

Extraskeletal benefits and risks of calcium, vitamin D and anti-osteoporosis medications. Osteoporos Int (2012) 0.91

Higher blood 25(OH)D level may reduce the breast cancer risk: evidence from a Chinese population based case-control study and meta-analysis of the observational studies. PLoS One (2013) 0.91

Dietary vitamin D and calcium intake and mammographic density in postmenopausal women. Menopause (2010) 0.90

Prognostic significance of vitamin D receptor polymorphisms in head and neck squamous cell carcinoma. PLoS One (2011) 0.88

The vitamin D pathway and mammographic breast density among postmenopausal women. Breast Cancer Res Treat (2011) 0.88

Circulating Vitamin D Levels and Risk of Colorectal Cancer in Women. Cancer Prev Res (Phila) (2015) 0.88

Vitamin D: marker or mechanism of action? Cancer Epidemiol Biomarkers Prev (2011) 0.88

Vitamin D and calcium supplementation and one-year change in mammographic density in the women's health initiative calcium and vitamin D trial. Cancer Epidemiol Biomarkers Prev (2012) 0.88

Inverse association between dietary vitamin D and risk of cutaneous melanoma in a northern Italy population. Nutr Cancer (2011) 0.87

Premenopausal plasma 25-hydroxyvitamin D, mammographic density, and risk of breast cancer. Breast Cancer Res Treat (2014) 0.87

Calcium and vitamin D in sarcoidosis: how to assess and manage. Semin Respir Crit Care Med (2010) 0.87

How I treat vitamin d deficiency. J Oncol Pract (2010) 0.87

Vitamin D supplementation and breast cancer prevention: a systematic review and meta-analysis of randomized clinical trials. PLoS One (2013) 0.87

Plasma free 25-hydroxyvitamin D, vitamin D binding protein, and risk of breast cancer in the Nurses' Health Study II. Cancer Causes Control (2014) 0.86

Plasma 25-hydroxyvitamin D3 is associated with decreased risk of postmenopausal breast cancer in whites: a nested case-control study in the multiethnic cohort study. BMC Cancer (2014) 0.86

Update on the Vitamin D and OmegA-3 trial (VITAL). J Steroid Biochem Mol Biol (2015) 0.85

Re: Calcium plus vitamin D supplementation and the risk of breast cancer. J Natl Cancer Inst (2009) 0.85

Does the evidence for an inverse relationship between serum vitamin D status and breast cancer risk satisfy the Hill criteria? Dermatoendocrinol (2012) 0.84

Transcriptional effects of 1,25 dihydroxyvitamin D(3) physiological and supra-physiological concentrations in breast cancer organotypic culture. BMC Cancer (2013) 0.84

Cellular calcium dynamics in lactation and breast cancer: from physiology to pathology. Am J Physiol Cell Physiol (2013) 0.84

Vitamin d: are we ready to supplement for breast cancer prevention and treatment? ISRN Oncol (2013) 0.83

Clinical utility of vitamin d testing: an evidence-based analysis. Ont Health Technol Assess Ser (2010) 0.83

Changes in vitamin and mineral supplement use after breast cancer diagnosis in the Pathways Study: a prospective cohort study. BMC Cancer (2014) 0.83

25-hydroxyvitamin D concentration, vitamin D intake and joint symptoms in postmenopausal women. Maturitas (2010) 0.82

Natural compounds as anticancer agents: Experimental evidence. World J Exp Med (2012) 0.82

Dietary supplements and disease prevention - a global overview. Nat Rev Endocrinol (2016) 0.81

Resampling Procedures for Making Inference under Nested Case-control Studies. J Am Stat Assoc (2013) 0.81

Vitamin D, chronic kidney disease and survival: a pluripotent hormone or just another bone drug? Pediatr Nephrol (2010) 0.81

Lead, calcium uptake, and related genetic variants in association with renal cell carcinoma risk in a cohort of male Finnish smokers. Cancer Epidemiol Biomarkers Prev (2011) 0.81

Association between serum vitamin D status and health-related quality of life (HRQOL) in an older Korean population with radiographic knee osteoarthritis: data from the Korean national health and nutrition examination survey (2010-2011). Health Qual Life Outcomes (2015) 0.81

Vitamin D receptor gene polymorphisms in breast and renal cancer: current state and future approaches (review). Int J Oncol (2013) 0.80

Vitamin D intake, month the mammogram was taken and mammographic density in Norwegian women aged 50-69. PLoS One (2015) 0.79

Calcium plus vitamin D supplementation and joint symptoms in postmenopausal women in the women's health initiative randomized trial. J Acad Nutr Diet (2013) 0.78

Vitamin D and cardiovascular disease and cancer: not too much and not too little? The need for clinical trials. Womens Health (Lond Engl) (2011) 0.78

Serum Calcium and the Risk of Breast Cancer: Findings from the Swedish AMORIS Study and a Meta-Analysis of Prospective Studies. Int J Mol Sci (2016) 0.78

Plasma 25-Hydroxyvitamin D and Risk of Breast Cancer in Women Followed over 20 Years. Cancer Res (2016) 0.77

The "Got D'ViBE?" study: an inter-institutional project assessing vitamin D and mammographic breast density. J Health Care Poor Underserved (2010) 0.77

Optimizing vitamin D concentrations for breast cancer risk reduction. Medicine (Baltimore) (2013) 0.77

Vitamin D and Cancer: Diversity, Complexity, and Still a Ways to Go. Cancer Prev Res (Phila) (2015) 0.76

Vitamin D receptor and RXR in the post-genomic era. J Cell Physiol (2015) 0.76

Integration of VDR genome wide binding and GWAS genetic variation data reveals co-occurrence of VDR and NF-κB binding that is linked to immune phenotypes. BMC Genomics (2017) 0.76

The Use of 1α,25-Dihydroxyvitamin D₃ as an Anticancer Agent. Int J Mol Sci (2016) 0.76

Concordance of Results from Randomized and Observational Analyses within the Same Study: A Re-Analysis of the Women's Health Initiative Limited-Access Dataset. PLoS One (2015) 0.76

Independent and joint effects of serum 25-hydroxivitamin D and calcium on breast cancer ratio in an Iran population: A cross-sectional study. Niger Med J (2016) 0.75

Calcium intake is not related to breast cancer risk among Singapore Chinese women. Int J Cancer (2013) 0.75

Mammographic Density and Vitamin D Levels - A Cross-sectional Study. Geburtshilfe Frauenheilkd (2017) 0.75

Bone: causes of low bone mass in breast cancer-time for action? Nat Rev Endocrinol (2010) 0.75

A novel method for non-destructive determination of hair photo-induced damage based on multispectral imaging technology. Sci Rep (2017) 0.75

25-Hydroxyvitamin D and TSH as Risk Factors or Prognostic Markers in Thyroid Carcinoma. PLoS One (2016) 0.75

Breast cancer prevention using calcium and vitamin D: a bright future? J Natl Cancer Inst (2008) 0.75

Vitamins, Are They Safe? Adv Pharm Bull (2016) 0.75

Update in new medications for primary care. J Gen Intern Med (2010) 0.75

Baseline characteristics of participants in the VITamin D and OmegA-3 TriaL (VITAL). Contemp Clin Trials (2016) 0.75

Predicted 25-hydroxyvitamin D in relation to incidence of breast cancer in a large cohort of African American women. Breast Cancer Res (2016) 0.75

Breast cancer survival and season of surgery: an ecological open cohort study. BMJ Open (2012) 0.75

Incidence of hematologic malignancy and cause-specific mortality in the Women's Health Initiative randomized controlled trial of calcium and vitamin D supplementation. Cancer (2017) 0.75

Association between Vitamin D deficiency and Breast Cancer. Pak J Med Sci (2017) 0.75

Articles cited by this

Risks and benefits of estrogen plus progestin in healthy postmenopausal women: principal results From the Women's Health Initiative randomized controlled trial. JAMA (2002) 80.37

Adherence to medication. N Engl J Med (2005) 39.77

Effects of conjugated equine estrogen in postmenopausal women with hysterectomy: the Women's Health Initiative randomized controlled trial. JAMA (2004) 23.69

Tamoxifen for prevention of breast cancer: report of the National Surgical Adjuvant Breast and Bowel Project P-1 Study. J Natl Cancer Inst (1998) 22.10

Calcium plus vitamin D supplementation and the risk of fractures. N Engl J Med (2006) 12.09

Effects of tamoxifen vs raloxifene on the risk of developing invasive breast cancer and other disease outcomes: the NSABP Study of Tamoxifen and Raloxifene (STAR) P-2 trial. JAMA (2006) 11.22

Calcium plus vitamin D supplementation and the risk of colorectal cancer. N Engl J Med (2006) 8.73

Interventions to enhance patient adherence to medication prescriptions: scientific review. JAMA (2002) 8.30

Low-fat dietary pattern and risk of invasive breast cancer: the Women's Health Initiative Randomized Controlled Dietary Modification Trial. JAMA (2006) 6.51

The role of vitamin D in cancer prevention. Am J Public Health (2005) 4.99

The urgent need to recommend an intake of vitamin D that is effective. Am J Clin Nutr (2007) 4.36

Effectiveness and safety of vitamin D in relation to bone health. Evid Rep Technol Assess (Full Rep) (2007) 3.51

Intakes of calcium and vitamin D and breast cancer risk in women. Arch Intern Med (2007) 2.95

The Women's Health Initiative calcium-vitamin D trial: overview and baseline characteristics of participants. Ann Epidemiol (2003) 2.42

Plasma 25-hydroxyvitamin D and 1,25-dihydroxyvitamin D and risk of breast cancer. Cancer Epidemiol Biomarkers Prev (2005) 2.37

Vitamin D and breast cancer risk: the NHANES I Epidemiologic follow-up study, 1971-1975 to 1992. National Health and Nutrition Examination Survey. Cancer Epidemiol Biomarkers Prev (1999) 2.24

Vitamin D and prevention of breast cancer: pooled analysis. J Steroid Biochem Mol Biol (2007) 2.20

Intake of dairy products, calcium, and vitamin d and risk of breast cancer. J Natl Cancer Inst (2002) 2.16

Serum 25-hydroxyvitamin D and risk of post-menopausal breast cancer--results of a large case-control study. Carcinogenesis (2007) 2.07

Plasma 25-hydroxy vitamin D concentrations, vitamin D receptor genotype and breast cancer risk in a UK Caucasian population. Eur J Cancer (2005) 1.83

Vitamin D, calcium, and breast cancer risk: a review. Cancer Epidemiol Biomarkers Prev (2006) 1.82

Serum levels of vitamin D metabolites and breast cancer risk in the prostate, lung, colorectal, and ovarian cancer screening trial. Cancer Epidemiol Biomarkers Prev (2008) 1.80

CYP2R1 (vitamin D 25-hydroxylase) gene is associated with susceptibility to type 1 diabetes and vitamin D levels in Germans. Diabetes Metab Res Rev (2007) 1.74

Molecular basis of the potential of vitamin D to prevent cancer. Curr Med Res Opin (2008) 1.66

Vitamin D and breast cancer: insights from animal models. Am J Clin Nutr (2004) 1.51

Dairy, calcium, and vitamin D intake and postmenopausal breast cancer risk in the Cancer Prevention Study II Nutrition Cohort. Cancer Epidemiol Biomarkers Prev (2005) 1.44

American Society of Clinical Oncology technology assessment of pharmacologic interventions for breast cancer risk reduction including tamoxifen, raloxifene, and aromatase inhibition. J Clin Oncol (2002) 1.42

Dietary intake of selected micronutrients and breast-cancer risk. Int J Cancer (2001) 1.35

Vitamin D intake and breast cancer risk in postmenopausal women: the Iowa Women's Health Study. Cancer Causes Control (2007) 1.33

Calcium plus vitamin D and the risk of colorectal cancer. N Engl J Med (2006) 1.32

Serum calcium and breast cancer risk: results from a prospective cohort study of 7,847 women. Cancer Causes Control (2007) 1.22

Intake of food groups and associated micronutrients in relation to risk of early-stage breast cancer. Int J Cancer (1999) 1.13

Intake of vitamin D and risk of breast cancer--a meta-analysis. J Steroid Biochem Mol Biol (2008) 1.06

Dairy products, calcium and the risk of breast cancer: results of the French SU.VI.MAX prospective study. Ann Nutr Metab (2007) 1.01

Vitamin D status and breast cancer risk. Anticancer Res (2006) 0.95

Prospective studies of dietary vitamin D and breast cancer: more questions raised than answered. Nutr Rev (2007) 0.91

Intake of selected foods and nutrients and breast cancer risk: an age- and menopause-specific analysis. Nutr Cancer (1997) 0.88

Substantial genetic effects involved in determination of circulating levels of calciotropic hormones in human pedigrees. Biochem Genet (2003) 0.82

Articles by these authors

Risks and benefits of estrogen plus progestin in healthy postmenopausal women: principal results From the Women's Health Initiative randomized controlled trial. JAMA (2002) 80.37

Effects of conjugated equine estrogen in postmenopausal women with hysterectomy: the Women's Health Initiative randomized controlled trial. JAMA (2004) 23.69

A Randomized Trial of Intensive versus Standard Blood-Pressure Control. N Engl J Med (2015) 19.14

Cardiovascular effects of intensive lifestyle intervention in type 2 diabetes. N Engl J Med (2013) 15.58

Revised Bethesda Guidelines for hereditary nonpolyposis colorectal cancer (Lynch syndrome) and microsatellite instability. J Natl Cancer Inst (2004) 14.97

Reduction in weight and cardiovascular disease risk factors in individuals with type 2 diabetes: one-year results of the look AHEAD trial. Diabetes Care (2007) 14.35

Low-fat dietary pattern and risk of cardiovascular disease: the Women's Health Initiative Randomized Controlled Dietary Modification Trial. JAMA (2006) 12.44

Calcium plus vitamin D supplementation and the risk of fractures. N Engl J Med (2006) 12.09

Estrogen plus progestin and the incidence of dementia and mild cognitive impairment in postmenopausal women: the Women's Health Initiative Memory Study: a randomized controlled trial. JAMA (2003) 11.39

Influence of estrogen plus progestin on breast cancer and mammography in healthy postmenopausal women: the Women's Health Initiative Randomized Trial. JAMA (2003) 10.61

Estrogen plus progestin and the risk of coronary heart disease. N Engl J Med (2003) 10.06

Look AHEAD (Action for Health in Diabetes): design and methods for a clinical trial of weight loss for the prevention of cardiovascular disease in type 2 diabetes. Control Clin Trials (2003) 9.97

Maternal and perinatal outcomes associated with a trial of labor after prior cesarean delivery. N Engl J Med (2004) 9.62

Calcium plus vitamin D supplementation and the risk of colorectal cancer. N Engl J Med (2006) 8.73

Outcomes ascertainment and adjudication methods in the Women's Health Initiative. Ann Epidemiol (2003) 8.64

The Women's Health Initiative recruitment methods and results. Ann Epidemiol (2003) 8.42

A multistage genome-wide association study in breast cancer identifies two new risk alleles at 1p11.2 and 14q24.1 (RAD51L1). Nat Genet (2009) 8.39

Exemestane for breast-cancer prevention in postmenopausal women. N Engl J Med (2011) 8.19

The histone modification pattern of active genes revealed through genome-wide chromatin analysis of a higher eukaryote. Genes Dev (2004) 7.57

Menopausal hormone therapy and health outcomes during the intervention and extended poststopping phases of the Women's Health Initiative randomized trials. JAMA (2013) 7.19

Estrogen plus progestin and breast cancer incidence and mortality in postmenopausal women. JAMA (2010) 7.12

Calcium/vitamin D supplementation and cardiovascular events. Circulation (2007) 6.63

Low-fat dietary pattern and risk of invasive breast cancer: the Women's Health Initiative Randomized Controlled Dietary Modification Trial. JAMA (2006) 6.51

Statin use and risk of diabetes mellitus in postmenopausal women in the Women's Health Initiative. Arch Intern Med (2012) 6.46

Performance of common genetic variants in breast-cancer risk models. N Engl J Med (2010) 5.79

Low-fat dietary pattern and weight change over 7 years: the Women's Health Initiative Dietary Modification Trial. JAMA (2006) 5.75

Estrogen plus progestin and colorectal cancer in postmenopausal women. N Engl J Med (2004) 5.65

Ethnicity and breast cancer: factors influencing differences in incidence and outcome. J Natl Cancer Inst (2005) 5.52

Genome-wide meta-analysis identifies 56 bone mineral density loci and reveals 14 loci associated with risk of fracture. Nat Genet (2012) 5.48

Loss-of-function mutations in APOC3, triglycerides, and coronary disease. N Engl J Med (2014) 5.47

Effect of estrogen plus progestin on stroke in postmenopausal women: the Women's Health Initiative: a randomized trial. JAMA (2003) 5.26

Oestrogen plus progestin and lung cancer in postmenopausal women (Women's Health Initiative trial): a post-hoc analysis of a randomised controlled trial. Lancet (2009) 5.22

Association of an intensive lifestyle intervention with remission of type 2 diabetes. JAMA (2012) 5.15

Genome-wide association study identifies variants in the ABO locus associated with susceptibility to pancreatic cancer. Nat Genet (2009) 5.14

Trends and disparities in socioeconomic and behavioural characteristics, life expectancy, and cause-specific mortality of native-born and foreign-born populations in the United States, 1979-2003. Int J Epidemiol (2006) 4.99

A genome-wide association study identifies pancreatic cancer susceptibility loci on chromosomes 13q22.1, 1q32.1 and 5p15.33. Nat Genet (2010) 4.89

Effects of estrogen plus progestin on health-related quality of life. N Engl J Med (2003) 4.83

Breast cancer after use of estrogen plus progestin in postmenopausal women. N Engl J Med (2009) 4.80

Recreational physical activity and the risk of breast cancer in postmenopausal women: the Women's Health Initiative Cohort Study. JAMA (2003) 4.72

Genome-wide DNA replication profile for Drosophila melanogaster: a link between transcription and replication timing. Nat Genet (2002) 4.68

Combined postmenopausal hormone therapy and cardiovascular disease: toward resolving the discrepancy between observational studies and the Women's Health Initiative clinical trial. Am J Epidemiol (2005) 4.55

Health risks and benefits 3 years after stopping randomized treatment with estrogen and progestin. JAMA (2008) 4.42

Fast food restaurants and food stores: longitudinal associations with diet in young to middle-aged adults: the CARDIA study. Arch Intern Med (2011) 4.40

Diffusion theory and knowledge dissemination, utilization, and integration in public health. Annu Rev Public Health (2009) 4.33

One-year weight losses in the Look AHEAD study: factors associated with success. Obesity (Silver Spring) (2009) 4.08

Effects of estrogen plus progestin on risk of fracture and bone mineral density: the Women's Health Initiative randomized trial. JAMA (2003) 4.07

Interventions to prevent skin cancer by reducing exposure to ultraviolet radiation: a systematic review. Am J Prev Med (2004) 4.07

Effect of estrogen plus progestin on global cognitive function in postmenopausal women: the Women's Health Initiative Memory Study: a randomized controlled trial. JAMA (2003) 4.03

Approaching health disparities from a population perspective: the National Institutes of Health Centers for Population Health and Health Disparities. Am J Public Health (2008) 3.98

Regional and cellular gene expression changes in human Huntington's disease brain. Hum Mol Genet (2006) 3.91

Conjugated equine estrogens and coronary heart disease: the Women's Health Initiative. Arch Intern Med (2006) 3.91

Coding Variation in ANGPTL4, LPL, and SVEP1 and the Risk of Coronary Disease. N Engl J Med (2016) 3.88

Health outcomes after stopping conjugated equine estrogens among postmenopausal women with prior hysterectomy: a randomized controlled trial. JAMA (2011) 3.85

Detectable clonal mosaicism and its relationship to aging and cancer. Nat Genet (2012) 3.69

Conjugated equine oestrogen and breast cancer incidence and mortality in postmenopausal women with hysterectomy: extended follow-up of the Women's Health Initiative randomised placebo-controlled trial. Lancet Oncol (2012) 3.56

Comparison of self-report, hospital discharge codes, and adjudication of cardiovascular events in the Women's Health Initiative. Am J Epidemiol (2004) 3.53

Diabetes, metformin, and breast cancer in postmenopausal women. J Clin Oncol (2012) 3.47