Published in Science on November 13, 2008
The ESCRT machinery in endosomal sorting of ubiquitylated membrane proteins. Nature (2009) 6.99
Bacterial cell division: assembly, maintenance and disassembly of the Z ring. Nat Rev Microbiol (2009) 4.66
Membrane scission by the ESCRT-III complex. Nature (2009) 4.66
Membrane budding and scission by the ESCRT machinery: it's all in the neck. Nat Rev Mol Cell Biol (2010) 4.29
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ESCRT-III governs the Aurora B-mediated abscission checkpoint through CHMP4C. Science (2012) 2.59
Dynamics of endosomal sorting complex required for transport (ESCRT) machinery during cytokinesis and its role in abscission. Proc Natl Acad Sci U S A (2011) 2.45
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Human ESCRT-III and VPS4 proteins are required for centrosome and spindle maintenance. Proc Natl Acad Sci U S A (2010) 1.89
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FisB mediates membrane fission during sporulation in Bacillus subtilis. Genes Dev (2013) 1.59
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ALIX and ESCRT-III coordinately control cytokinetic abscission during germline stem cell division in vivo. PLoS Genet (2015) 1.43
Plk1 negatively regulates Cep55 recruitment to the midbody to ensure orderly abscission. J Cell Biol (2010) 1.43
The ESCRT machinery at a glance. J Cell Sci (2009) 1.41
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Shaping development with ESCRTs. Nat Cell Biol (2011) 1.38
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Electron cryotomography of ESCRT assemblies and dividing Sulfolobus cells suggests that spiraling filaments are involved in membrane scission. Mol Biol Cell (2013) 1.01
Structural basis for ESCRT-III CHMP3 recruitment of AMSH. Structure (2011) 1.00
Cell division without FtsZ--a variety of redundant mechanisms. Mol Microbiol (2010) 0.99
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Crenarchaeal CdvA forms double-helical filaments containing DNA and interacts with ESCRT-III-like CdvB. PLoS One (2011) 0.98
Resurrecting remnants: the lives of post-mitotic midbodies. Trends Cell Biol (2012) 0.98
Crenactin from Pyrobaculum calidifontis is closely related to actin in structure and forms steep helical filaments. FEBS Lett (2014) 0.97
Replication termination and chromosome dimer resolution in the archaeon Sulfolobus solfataricus. EMBO J (2010) 0.97
Archaeal origin of tubulin. Biol Direct (2012) 0.97
The N-terminal amphipathic helix of the topological specificity factor MinE is associated with shaping membrane curvature. PLoS One (2011) 0.97
The oligomeric state of the active Vps4 AAA ATPase. J Mol Biol (2013) 0.95
Incisive imaging and computation for cellular mysteries: lessons from abscission. Cell (2013) 0.95
Multivesicular bodies in the enigmatic amoeboflagellate Breviata anathema and the evolution of ESCRT 0. J Cell Sci (2011) 0.95
CC2D1A is a regulator of ESCRT-III CHMP4B. J Mol Biol (2012) 0.95
Novel insights into gene regulation of the rudivirus SIRV2 infecting Sulfolobus cells. RNA Biol (2013) 0.95
Structural basis of molecular recognition between ESCRT-III-like protein Vps60 and AAA-ATPase regulator Vta1 in the multivesicular body pathway. J Biol Chem (2012) 0.95
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ESCRT-III CHMP2A and CHMP3 form variable helical polymers in vitro and act synergistically during HIV-1 budding. Cell Microbiol (2012) 0.92
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Two new families of the FtsZ-tubulin protein superfamily implicated in membrane remodeling in diverse bacteria and archaea. Biol Direct (2010) 0.91
Functional interplay between a virus and the ESCRT machinery in archaea. Proc Natl Acad Sci U S A (2013) 0.90
An archaeal origin for the actin cytoskeleton: Implications for eukaryogenesis. Commun Integr Biol (2011) 0.89
Proteomic analysis of Sulfolobus solfataricus during Sulfolobus Turreted Icosahedral Virus infection. J Proteome Res (2012) 0.89
Assembly and disassembly of the ESCRT-III membrane scission complex. FEBS Lett (2011) 0.89
Relief of autoinhibition enhances Vta1 activation of Vps4 via the Vps4 stimulatory element. J Biol Chem (2013) 0.88
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Wrapping up the bad news: HIV assembly and release. Retrovirology (2013) 0.88
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Differential physiological roles of ESCRT complexes in Caenorhabditis elegans. Mol Cells (2011) 0.87
Structure of the trehalose-6-phosphate phosphatase from Brugia malayi reveals key design principles for anthelmintic drugs. PLoS Pathog (2014) 0.87
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Two distinct binding modes define the interaction of Brox with the C-terminal tails of CHMP5 and CHMP4B. Structure (2012) 0.85
The sub-cellular localization of Sulfolobus DNA replication. Nucleic Acids Res (2012) 0.85
The eocyte hypothesis and the origin of eukaryotic cells. Proc Natl Acad Sci U S A (2008) 0.85
ESCRT-III binding protein MITD1 is involved in cytokinesis and has an unanticipated PLD fold that binds membranes. Proc Natl Acad Sci U S A (2012) 0.84
Exploring microbial dark matter to resolve the deep archaeal ancestry of eukaryotes. Philos Trans R Soc Lond B Biol Sci (2015) 0.84
Diversity and subcellular distribution of archaeal secreted proteins. Front Microbiol (2012) 0.84
Divided we stand: splitting synthetic cells for their proliferation. Syst Synth Biol (2014) 0.84
Endocytic regulation of alkali metal transport proteins in mammals, yeast and plants. Curr Genet (2013) 0.84
Distinct mechanisms of recognizing endosomal sorting complex required for transport III (ESCRT-III) protein IST1 by different microtubule interacting and trafficking (MIT) domains. J Biol Chem (2015) 0.83
Replication-biased genome organisation in the crenarchaeon Sulfolobus. BMC Genomics (2010) 0.83
Binding of Substrates to the Central Pore of the Vps4 ATPase Is Autoinhibited by the Microtubule Interacting and Trafficking (MIT) Domain and Activated by MIT Interacting Motifs (MIMs). J Biol Chem (2015) 0.83
Meiotic Clade AAA ATPases: Protein Polymer Disassembly Machines. J Mol Biol (2015) 0.82
Evidence for a Nonendosomal Function of the Saccharomyces cerevisiae ESCRT-III-Like Protein Chm7. Genetics (2015) 0.82
Close encounters of the third domain: the emerging genomic view of archaeal diversity and evolution. Archaea (2013) 0.82
Crenactin forms actin-like double helical filaments regulated by arcadin-2. Elife (2016) 0.81
Protein functional links in Trypanosoma brucei, identified by gene fusion analysis. BMC Evol Biol (2011) 0.80
Asymmetric ring structure of Vps4 required for ESCRT-III disassembly. Nat Commun (2015) 0.80
ESCRT requirements for EIAV budding. Retrovirology (2013) 0.80
Archaeal dominance in the mesopelagic zone of the Pacific Ocean. Nature (2001) 7.21
Parallels between cytokinesis and retroviral budding: a role for the ESCRT machinery. Science (2007) 6.13
The emerging shape of the ESCRT machinery. Nat Rev Mol Cell Biol (2007) 6.05
Human ESCRT and ALIX proteins interact with proteins of the midbody and function in cytokinesis. EMBO J (2007) 5.31
The ESCRT complexes: structure and mechanism of a membrane-trafficking network. Annu Rev Biophys Biomol Struct (2006) 5.21
FtsZ and the division of prokaryotic cells and organelles. Nat Rev Mol Cell Biol (2005) 4.27
Biogenesis and function of multivesicular bodies. Annu Rev Cell Dev Biol (2007) 4.08
ESCRT-III recognition by VPS4 ATPases. Nature (2007) 3.64
Structural basis for selective recognition of ESCRT-III by the AAA ATPase Vps4. Nature (2007) 3.47
Abundance and diversity of microbial life in ocean crust. Nature (2008) 2.50
Two distinct modes of ESCRT-III recognition are required for VPS4 functions in lysosomal protein targeting and HIV-1 budding. Dev Cell (2008) 2.23
Beyond Tsg101: the role of Alix in 'ESCRTing' HIV-1. Nat Rev Microbiol (2007) 2.08
A dynamic bacterial cytoskeleton. Trends Cell Biol (2003) 1.77
The Arabidopsis elch mutant reveals functions of an ESCRT component in cytokinesis. Development (2006) 1.74
The role of ubiquitin in retroviral egress. Traffic (2007) 1.68
Characterization of the archaeal thermophile Sulfolobus turreted icosahedral virus validates an evolutionary link among double-stranded DNA viruses from all domains of life. J Virol (2006) 1.44
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Chromosome replication dynamics in the archaeon Sulfolobus acidocaldarius. Proc Natl Acad Sci U S A (2008) 1.31
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The push and pull of the bacterial cytoskeleton. Trends Cell Biol (2007) 1.17
The Sulfolobus solfataricus AAA protein Sso0909, a homologue of the eukaryotic ESCRT Vps4 ATPase. Biochem Soc Trans (2008) 1.07
Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy (2012) 20.08
A pharmacological map of the PI3-K family defines a role for p110alpha in insulin signaling. Cell (2006) 10.06
Mechanism of two classes of cancer mutations in the phosphoinositide 3-kinase catalytic subunit. Science (2007) 5.19
Targeted polypharmacology: discovery of dual inhibitors of tyrosine and phosphoinositide kinases. Nat Chem Biol (2008) 3.84
Identification of two origins of replication in the single chromosome of the archaeon Sulfolobus solfataricus. Cell (2004) 3.63
Structural basis for selective recognition of ESCRT-III by the AAA ATPase Vps4. Nature (2007) 3.47
Phosphoinositide 3-kinase δ gene mutation predisposes to respiratory infection and airway damage. Science (2013) 3.33
Shaping development of autophagy inhibitors with the structure of the lipid kinase Vps34. Science (2010) 3.20
The p110 delta structure: mechanisms for selectivity and potency of new PI(3)K inhibitors. Nat Chem Biol (2010) 3.15
Organization of the archaeal MCM complex on DNA and implications for the helicase mechanism. Nat Struct Mol Biol (2005) 3.04
Solution structure of the nonmethyl-CpG-binding CXXC domain of the leukaemia-associated MLL histone methyltransferase. EMBO J (2006) 2.89
ESCRT-II, an endosome-associated complex required for protein sorting: crystal structure and interactions with ESCRT-III and membranes. Dev Cell (2004) 2.86
Structure of lipid kinase p110β/p85β elucidates an unusual SH2-domain-mediated inhibitory mechanism. Mol Cell (2011) 2.50
ESCRT-I core and ESCRT-II GLUE domain structures reveal role for GLUE in linking to ESCRT-I and membranes. Cell (2006) 2.38
A heterotrimeric PCNA in the hyperthermophilic archaeon Sulfolobus solfataricus. Mol Cell (2003) 2.34
DNA replication in the archaea. Microbiol Mol Biol Rev (2006) 2.17
Replication origin recognition and deformation by a heterodimeric archaeal Orc1 complex. Science (2007) 2.10
Binding of the PX domain of p47(phox) to phosphatidylinositol 3,4-bisphosphate and phosphatidic acid is masked by an intramolecular interaction. EMBO J (2002) 2.09
The extracellular matrix protein TGFBI induces microtubule stabilization and sensitizes ovarian cancers to paclitaxel. Cancer Cell (2007) 2.05
Oncogenic mutations mimic and enhance dynamic events in the natural activation of phosphoinositide 3-kinase p110α (PIK3CA). Proc Natl Acad Sci U S A (2012) 2.04
Structure and disassembly of filaments formed by the ESCRT-III subunit Vps24. Structure (2008) 1.95
GINS, a central nexus in the archaeal DNA replication fork. EMBO Rep (2006) 1.91
Four domains of p300 each bind tightly to a sequence spanning both transactivation subdomains of p53. Proc Natl Acad Sci U S A (2007) 1.86
ATPase site architecture and helicase mechanism of an archaeal MCM. Mol Cell (2007) 1.84
PB1 domain-mediated heterodimerization in NADPH oxidase and signaling complexes of atypical protein kinase C with Par6 and p62. Mol Cell (2003) 1.78
Structure-guided identification of a new catalytic motif of oligosaccharyltransferase. EMBO J (2007) 1.76
The FtsK gamma domain directs oriented DNA translocation by interacting with KOPS. Nat Struct Mol Biol (2006) 1.76
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Structural insight into the ESCRT-I/-II link and its role in MVB trafficking. EMBO J (2007) 1.60
Structural insights into endosomal sorting complex required for transport (ESCRT-I) recognition of ubiquitinated proteins. J Biol Chem (2004) 1.57
Evolution of diverse cell division and vesicle formation systems in Archaea. Nat Rev Microbiol (2010) 1.55
Structural role of Sfi1p-centrin filaments in budding yeast spindle pole body duplication. J Cell Biol (2006) 1.51
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Sir2 and the acetyltransferase, Pat, regulate the archaeal chromatin protein, Alba. J Biol Chem (2005) 1.47
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Lack of medication dose uniformity in commonly split tablets. J Am Pharm Assoc (Wash) (2002) 1.46
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Balancing efficacy and safety in the use of oral sedation in dental outpatients. J Am Dent Assoc (2006) 1.42
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G protein-coupled receptor-mediated activation of p110β by Gβγ is required for cellular transformation and invasiveness. Sci Signal (2012) 1.38
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MCM forked substrate specificity involves dynamic interaction with the 5'-tail. J Biol Chem (2007) 1.32
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Tom20 recognizes mitochondrial presequences through dynamic equilibrium among multiple bound states. EMBO J (2007) 1.31
The Sulfolobus solfataricus Lrp-like protein LysM regulates lysine biosynthesis in response to lysine availability. J Biol Chem (2002) 1.30
Archaeal MCM has separable processivity, substrate choice and helicase domains. Nucleic Acids Res (2007) 1.29
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Regulation of minichromosome maintenance helicase activity by Cdc6. J Biol Chem (2003) 1.28
Application of USP-NF Standard to Pharmacy Compounding. Int J Pharm Compd (2013) 1.27
Structural basis for the NAD-dependent deacetylase mechanism of Sir2. J Biol Chem (2002) 1.26
Structural and membrane binding analysis of the Phox homology domain of Bem1p: basis of phosphatidylinositol 4-phosphate specificity. J Biol Chem (2007) 1.22
Ancient ESCRTs and the evolution of binary fission. Trends Microbiol (2009) 1.20
Physical and functional interactions between human mitochondrial single-stranded DNA-binding protein and tumour suppressor p53. Nucleic Acids Res (2008) 1.18
Structural insight into recruitment of translesion DNA polymerase Dpo4 to sliding clamp PCNA. Mol Microbiol (2008) 1.14
Biophysical characterizations of human mitochondrial transcription factor A and its binding to tumor suppressor p53. Nucleic Acids Res (2009) 1.13
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The USP Performance Verification Test, Part I: USP Lot P Prednisone Tablets: quality attributes and experimental variables contributing to dissolution variance. Pharm Res (2008) 1.13
Features critical for membrane binding revealed by DivIVA crystal structure. EMBO J (2010) 1.12
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An intrinsically labile α-helix abutting the BCL9-binding site of β-catenin is required for its inhibition by carnosic acid. Nat Commun (2012) 1.11
Tumour prevention by a single antibody domain targeting the interaction of signal transduction proteins with RAS. EMBO J (2007) 1.11
Physical and functional interaction of the archaeal single-stranded DNA-binding protein SSB with RNA polymerase. Nucleic Acids Res (2004) 1.11
The chromosome replication machinery of the archaeon Sulfolobus solfataricus. J Biol Chem (2006) 1.11
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Characterization of an archaeal family 4 uracil DNA glycosylase and its interaction with PCNA and chromatin proteins. Biochem J (2005) 1.09
The UBAP1 subunit of ESCRT-I interacts with ubiquitin via a SOUBA domain. Structure (2012) 1.09
Molecular determinants of PI3Kγ-mediated activation downstream of G-protein-coupled receptors (GPCRs). Proc Natl Acad Sci U S A (2013) 1.06
Structural and membrane binding analysis of the Phox homology domain of phosphoinositide 3-kinase-C2alpha. J Biol Chem (2006) 1.05
Dynamic steps in receptor tyrosine kinase mediated activation of class IA phosphoinositide 3-kinases (PI3K) captured by H/D exchange (HDX-MS). Adv Biol Regul (2012) 1.05
Intersubunit allosteric communication mediated by a conserved loop in the MCM helicase. Proc Natl Acad Sci U S A (2009) 1.05
Interaction between the transactivation domain of p53 and PC4 exemplifies acidic activation domains as single-stranded DNA mimics. J Biol Chem (2009) 1.04
Eukaryotic/archaeal primase and MCM proteins encoded in a bacteriophage genome. Cell (2005) 1.04
Molecular and structural basis of ESCRT-III recruitment to membranes during archaeal cell division. Mol Cell (2011) 1.03
Termination structures in the Escherichia coli chromosome replication fork trap. J Mol Biol (2009) 1.02
The role of phosphoinositides and phosphorylation in regulation of NADPH oxidase. Adv Enzyme Regul (2004) 1.02
Genome-wide analysis reveals extensive functional interaction between DNA replication initiation and transcription in the genome of Trypanosoma brucei. Cell Rep (2012) 1.01
Electron cryotomography of ESCRT assemblies and dividing Sulfolobus cells suggests that spiraling filaments are involved in membrane scission. Mol Biol Cell (2013) 1.01
On the mechanism of loading the PCNA sliding clamp by RFC. Mol Microbiol (2008) 1.01
Structural studies of phosphoinositide 3-kinase-dependent traffic to multivesicular bodies. Biochem Soc Symp (2007) 0.99
Specificity and function of archaeal DNA replication initiator proteins. Cell Rep (2013) 0.99
Molecular machines in archaeal DNA replication. Curr Opin Chem Biol (2011) 0.98
Vesicular and non-vesicular transport feed distinct glycosylation pathways in the Golgi. Nature (2013) 0.98
Molecular determinants of origin discrimination by Orc1 initiators in archaea. Nucleic Acids Res (2011) 0.98
Replication termination and chromosome dimer resolution in the archaeon Sulfolobus solfataricus. EMBO J (2010) 0.97
A novel archaeal regulatory protein, Sta1, activates transcription from viral promoters. Nucleic Acids Res (2006) 0.97
The Bre5/Ubp3 ubiquitin protease complex from budding yeast contributes to the cellular response to DNA damage. DNA Repair (Amst) (2007) 0.96
Structures of monomeric, dimeric and trimeric PCNA: PCNA-ring assembly and opening. Acta Crystallogr D Biol Crystallogr (2008) 0.95
Influence of chromatin and single strand binding proteins on the activity of an archaeal MCM. J Mol Biol (2006) 0.95
The USP Performance Verification Test, Part II: collaborative study of USP's Lot P Prednisone Tablets. Pharm Res (2008) 0.94
Purification, crystallization and preliminary X-ray diffraction studies of the soluble domain of the oligosaccharyltransferase STT3 subunit from the thermophilic archaeon Pyrococcus furiosus. Acta Crystallogr Sect F Struct Biol Cryst Commun (2007) 0.93