Published in J Biol Chem on December 12, 2008
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A central role for inflammation in the pathogenesis of diabetic retinopathy. FASEB J (2004) 5.33
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The Ins2Akita mouse as a model of early retinal complications in diabetes. Invest Ophthalmol Vis Sci (2005) 2.83
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Activation of PKC-delta and SHP-1 by hyperglycemia causes vascular cell apoptosis and diabetic retinopathy. Nat Med (2009) 2.31
Oxidative damage in the retinal mitochondria of diabetic mice: possible protection by superoxide dismutase. Invest Ophthalmol Vis Sci (2007) 2.28
Activation of nuclear factor-kappaB induced by diabetes and high glucose regulates a proapoptotic program in retinal pericytes. Diabetes (2002) 2.05
Sulfhydryl-mediated redox signaling in inflammation: role in neurodegenerative diseases. Arch Toxicol (2015) 2.04
Poly(ADP-ribose) polymerase is involved in the development of diabetic retinopathy via regulation of nuclear factor-kappaB. Diabetes (2004) 2.02
Ischemic vascular damage can be repaired by healthy, but not diabetic, endothelial progenitor cells. Diabetes (2007) 2.01
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Retinal ischemia and reperfusion causes capillary degeneration: similarities to diabetes. Invest Ophthalmol Vis Sci (2007) 1.90
Vascular damage in a mouse model of diabetic retinopathy: relation to neuronal and glial changes. Invest Ophthalmol Vis Sci (2005) 1.84
Salicylate-based anti-inflammatory drugs inhibit the early lesion of diabetic retinopathy. Diabetes (2007) 1.61
Probing active site chemistry in SHV beta-lactamase variants at Ambler position 244. Understanding unique properties of inhibitor resistance. J Biol Chem (2006) 1.60
Mechanistic and kinetic details of catalysis of thiol-disulfide exchange by glutaredoxins and potential mechanisms of regulation. Antioxid Redox Signal (2009) 1.50
5-Lipoxygenase, but not 12/15-lipoxygenase, contributes to degeneration of retinal capillaries in a mouse model of diabetic retinopathy. Diabetes (2008) 1.48
Compound 49b prevents diabetes-induced apoptosis through increased IGFBP-3 levels. Invest Ophthalmol Vis Sci (2012) 1.46
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A comprehensive analysis of the expression of crystallins in mouse retina. Mol Vis (2003) 1.43
Glycation of mitochondrial proteins from diabetic rat kidney is associated with excess superoxide formation. Am J Physiol Renal Physiol (2005) 1.43
Substrate selectivity and a novel role in inhibitor discrimination by residue 237 in the KPC-2 beta-lactamase. Antimicrob Agents Chemother (2010) 1.41
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Stable and controllable RNA interference: Investigating the physiological function of glutathionylated actin. Proc Natl Acad Sci U S A (2003) 1.36
Photoreceptor cells are major contributors to diabetes-induced oxidative stress and local inflammation in the retina. Proc Natl Acad Sci U S A (2013) 1.36
Effects of p38 MAPK inhibition on early stages of diabetic retinopathy and sensory nerve function. Invest Ophthalmol Vis Sci (2010) 1.31
Reduction of diabetes-induced oxidative stress, fibrotic cytokine expression, and renal dysfunction in protein kinase Cbeta-null mice. Diabetes (2006) 1.31
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Application of isoproterenol inhibits diabetic-like changes in the rat retina. Exp Eye Res (2010) 1.27
Retinal ion regulation in a mouse model of diabetic retinopathy: natural history and the effect of Cu/Zn superoxide dismutase overexpression. Invest Ophthalmol Vis Sci (2008) 1.27
Regulation by reversible S-glutathionylation: molecular targets implicated in inflammatory diseases. Mol Cells (2008) 1.26
Role of nitric oxide, superoxide, peroxynitrite and PARP in diabetic retinopathy. Front Biosci (Landmark Ed) (2009) 1.26
HSV infection induces production of ROS, which potentiate signaling from pattern recognition receptors: role for S-glutathionylation of TRAF3 and 6. PLoS Pathog (2011) 1.26
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Deglutathionylation of 2-Cys peroxiredoxin is specifically catalyzed by sulfiredoxin. J Biol Chem (2009) 1.25
Caspase activation in retinas of diabetic and galactosemic mice and diabetic patients. Diabetes (2002) 1.22
Marrow-derived cells regulate the development of early diabetic retinopathy and tactile allodynia in mice. Diabetes (2012) 1.21
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Glutaredoxin regulates nuclear factor kappa-B and intercellular adhesion molecule in Müller cells: model of diabetic retinopathy. J Biol Chem (2007) 1.19
Dysregulation of glutathione homeostasis in neurodegenerative diseases. Nutrients (2012) 1.18
IGFBP-3 and TNF-α regulate retinal endothelial cell apoptosis. Invest Ophthalmol Vis Sci (2013) 1.14
Reversible inactivation of alpha-ketoglutarate dehydrogenase in response to alterations in the mitochondrial glutathione status. Biochemistry (2003) 1.13
Design, synthesis, and crystal structures of 6-alkylidene-2'-substituted penicillanic acid sulfones as potent inhibitors of Acinetobacter baumannii OXA-24 carbapenemase. J Am Chem Soc (2010) 1.12
Increased basement membrane thickness, pericyte ghosts, and loss of retinal thickness and cells in dopamine beta hydroxylase knockout mice. Exp Eye Res (2009) 1.12
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What is the functional significance of the unique location of glutaredoxin 1 (GRx1) in the intermembrane space of mitochondria? Antioxid Redox Signal (2007) 1.10
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Increased tumor necrosis factor-α, cleaved caspase 3 levels and insulin receptor substrate-1 phosphorylation in the β₁-adrenergic receptor knockout mouse. Mol Vis (2011) 1.09
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Oxidation of fatty acids is the source of increased mitochondrial reactive oxygen species production in kidney cortical tubules in early diabetes. Diabetes (2012) 1.05
Inhibition of OXA-1 beta-lactamase by penems. Antimicrob Agents Chemother (2008) 1.04
Markers of glycemic control in the mouse: comparisons of 6-h- and overnight-fasted blood glucoses to Hb A1c. Am J Physiol Endocrinol Metab (2008) 1.04
Beneficial effects of a novel RAGE inhibitor on early diabetic retinopathy and tactile allodynia. Mol Vis (2011) 1.04
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Phosphorylation of rat liver mitochondrial carnitine palmitoyltransferase-I: effect on the kinetic properties of the enzyme. J Biol Chem (2004) 1.01
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Molecular mechanism of glutathione-mediated protection from oxidized low-density lipoprotein-induced cell injury in human macrophages: role of glutathione reductase and glutaredoxin. Free Radic Biol Med (2006) 1.00
Retracted Targets of tyrosine nitration in diabetic rat retina. Mol Cell Proteomics (2007) 1.00
Curcumin inhibits neuronal and vascular degeneration in retina after ischemia and reperfusion injury. PLoS One (2011) 0.98
Leukocytes regulate retinal capillary degeneration in the diabetic mouse via generation of leukotrienes. J Leukoc Biol (2012) 0.98
Covalent cross-linking of glutathione and carnosine to proteins by 4-oxo-2-nonenal. Chem Res Toxicol (2009) 0.98
Overcoming resistance to beta-lactamase inhibitors: comparing sulbactam to novel inhibitors against clavulanate resistant SHV enzymes with substitutions at Ambler position 244. Biochemistry (2007) 0.97
Acetylation of retinal histones in diabetes increases inflammatory proteins: effects of minocycline and manipulation of histone acetyltransferase (HAT) and histone deacetylase (HDAC). J Biol Chem (2012) 0.97
Identification of primary retinal cells and ex vivo detection of proinflammatory molecules using flow cytometry. Mol Vis (2009) 0.97
Non-enzymatic glycation in corneas from normal and diabetic donors and its effects on epithelial cell attachment in vitro. Optometry (2003) 0.96
Regulation of the early subnormal retinal oxygenation response in experimental diabetes by inducible nitric oxide synthase. Diabetes (2004) 0.95
MyD88-dependent pathways in leukocytes affect the retina in diabetes. PLoS One (2013) 0.94
Kinase inhibitors arrest neurodegeneration in cell and C. elegans models of LRRK2 toxicity. Hum Mol Genet (2012) 0.94
Captopril inhibits glucose accumulation in retinal cells in diabetes. Invest Ophthalmol Vis Sci (2003) 0.94
Sulfasalazine blocks the development of tactile allodynia in diabetic rats. Diabetes (2008) 0.92
Leukocytes from diabetic patients kill retinal endothelial cells: effects of berberine. Mol Vis (2013) 0.92
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Levodopa deactivates enzymes that regulate thiol-disulfide homeostasis and promotes neuronal cell death: implications for therapy of Parkinson's disease. Biochemistry (2010) 0.91
Deletion of aldose reductase from mice inhibits diabetes-induced retinal capillary degeneration and superoxide generation. PLoS One (2013) 0.89
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Glutaredoxin regulates apoptosis in cardiomyocytes via NFkappaB targets Bcl-2 and Bcl-xL: implications for cardiac aging. Antioxid Redox Signal (2010) 0.89
Selective inactivation of glutaredoxin by sporidesmin and other epidithiopiperazinediones. Biochemistry (2006) 0.88
A novel thiol oxidation-based mechanism for adriamycin-induced cell injury in human macrophages. FASEB J (2005) 0.88
Antagonism of CD11b with neutrophil inhibitory factor (NIF) inhibits vascular lesions in diabetic retinopathy. PLoS One (2013) 0.88
Exploring the inhibition of CTX-M-9 by beta-lactamase inhibitors and carbapenems. Antimicrob Agents Chemother (2011) 0.87
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Circulating mononuclear progenitor cells: differential roles for subpopulations in repair of retinal vascular injury. Invest Ophthalmol Vis Sci (2013) 0.86
Evidence for diffuse central retinal edema in vivo in diabetic male Sprague Dawley rats. PLoS One (2012) 0.86
Chronically elevated glucose-induced apoptosis is mediated by inactivation of Akt in cultured Müller cells. Biochem Biophys Res Commun (2005) 0.86
Comparison of glucose influx and blood flow in retina and brain of diabetic rats. J Cereb Blood Flow Metab (2004) 0.85
Captopril inhibits capillary degeneration in the early stages of diabetic retinopathy. Curr Eye Res (2007) 0.85
Levodopa activates apoptosis signaling kinase 1 (ASK1) and promotes apoptosis in a neuronal model: implications for the treatment of Parkinson's disease. Chem Res Toxicol (2011) 0.84