Published in N Engl J Med on December 17, 2008
Glycemic Control and Complications in Diabetes Mellitus Type 2 (VADT) (VADT) | NCT00032487
FLuctuATion Reduction With inSULin and Glp-1 Added togetheR (FLAT-SUGAR) (FLAT-SUGAR) | NCT01524705
HbA1c Variability in Type II Diabetes | NCT02879409
Allopurinol in Diabetes Mellitus and Multivessel Coronary Artery Disease | NCT03700645
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A randomized trial of therapies for type 2 diabetes and coronary artery disease. N Engl J Med (2009) 12.15
Effects of medical therapies on retinopathy progression in type 2 diabetes. N Engl J Med (2010) 10.75
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Comparative effectiveness of incident oral antidiabetic drugs on kidney function. Kidney Int (2012) 1.92
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Combined effects of routine blood pressure lowering and intensive glucose control on macrovascular and microvascular outcomes in patients with type 2 diabetes: New results from the ADVANCE trial. Diabetes Care (2009) 1.89
The effects of medical management on the progression of diabetic retinopathy in persons with type 2 diabetes: the Action to Control Cardiovascular Risk in Diabetes (ACCORD) Eye Study. Ophthalmology (2014) 1.89
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The ADDITION-Cambridge trial protocol: a cluster -- randomised controlled trial of screening for type 2 diabetes and intensive treatment for screen-detected patients. BMC Public Health (2009) 1.83
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Effects of acute hypoglycemia on inflammatory and pro-atherothrombotic biomarkers in individuals with type 1 diabetes and healthy individuals. Diabetes Care (2010) 1.71
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Myocardial infarction and stroke associated with diuretic based two drug antihypertensive regimens: population based case-control study. BMJ (2010) 1.58
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Effects of acute insulin-induced hypoglycemia on indices of inflammation: putative mechanism for aggravating vascular disease in diabetes. Diabetes Care (2010) 1.57
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Enhanced glucose control for preventing and treating diabetic neuropathy. Cochrane Database Syst Rev (2012) 1.51
The kidney in type 2 diabetes therapy. Rev Diabet Stud (2011) 1.50
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Sensitive cardiac troponin T assay and the risk of incident cardiovascular disease in women with and without diabetes mellitus: the Women's Health Study. Circulation (2011) 1.47
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Genetic and environmental factors associated with type 2 diabetes and diabetic vascular complications. Rev Diabet Stud (2012) 1.42
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Association of hypoglycemic treatment regimens with cardiovascular outcomes in overweight and obese subjects with type 2 diabetes: a substudy of the SCOUT trial. Diabetes Care (2013) 1.41
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The Michigan Model for Coronary Heart Disease in Type 2 Diabetes: Development and Validation. Diabetes Technol Ther (2015) 1.40
Death during intensive glycemic therapy of diabetes: mechanisms and implications. Am J Med (2011) 1.39
Stress Perfusion Cardiac Magnetic Resonance Imaging Effectively Risk Stratifies Diabetic Patients With Suspected Myocardial Ischemia. Circ Cardiovasc Imaging (2016) 1.37
Glucose, obesity, metabolic syndrome, and diabetes relevance to incidence of heart failure. J Am Coll Cardiol (2010) 1.36
Glycemic control and cardiovascular mortality in hemodialysis patients with diabetes: a 6-year cohort study. Diabetes (2012) 1.33
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Severe hypoglycemia predicts mortality in diabetes. Diabetes Care (2012) 1.31
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Hypoglycemia, diabetes, and cardiovascular disease. Diabetes Technol Ther (2012) 1.30
Effectiveness of sensor-augmented insulin-pump therapy in type 1 diabetes. N Engl J Med (2010) 8.69
Bilateral deep brain stimulation vs best medical therapy for patients with advanced Parkinson disease: a randomized controlled trial. JAMA (2009) 8.40
Open mesh versus laparoscopic mesh repair of inguinal hernia. N Engl J Med (2004) 8.24
Coronary-artery revascularization before elective major vascular surgery. N Engl J Med (2004) 7.80
Combined angiotensin inhibition for the treatment of diabetic nephropathy. N Engl J Med (2013) 7.29
Induction chemotherapy plus radiation compared with surgery plus radiation in patients with advanced laryngeal cancer. The Department of Veterans Affairs Laryngeal Cancer Study Group. N Engl J Med (1991) 6.39
Robot-assisted therapy for long-term upper-limb impairment after stroke. N Engl J Med (2010) 6.21
Hypoglycemia in diabetes. Diabetes Care (2003) 6.19
Integration of plant responses to environmentally activated phytohormonal signals. Science (2006) 5.46
Pallidal versus subthalamic deep-brain stimulation for Parkinson's disease. N Engl J Med (2010) 5.27
Determinants of long-term survival after major surgery and the adverse effect of postoperative complications. Ann Surg (2005) 4.95
Preoperative hematocrit levels and postoperative outcomes in older patients undergoing noncardiac surgery. JAMA (2007) 4.36
Pioglitazone for diabetes prevention in impaired glucose tolerance. N Engl J Med (2011) 4.28
A comprehensive care management program to prevent chronic obstructive pulmonary disease hospitalizations: a randomized, controlled trial. Ann Intern Med (2012) 4.10
Visualization of GC/TOF-MS-based metabolomics data for identification of biochemically interesting compounds using OPLS class models. Anal Chem (2007) 4.04
Risk of major adverse cardiac events following noncardiac surgery in patients with coronary stents. JAMA (2013) 3.88
The lack of a systematic validation of reference genes: a serious pitfall undervalued in reverse transcription-polymerase chain reaction (RT-PCR) analysis in plants. Plant Biotechnol J (2008) 3.81
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Randomized trial of deep brain stimulation for Parkinson disease: thirty-six-month outcomes. Neurology (2012) 3.46
The National Surgical Quality Improvement Program in non-veterans administration hospitals: initial demonstration of feasibility. Ann Surg (2002) 3.44
Factors associated with unanticipated day of surgery deaths in Department of Veterans Affairs hospitals. Anesth Analg (2008) 3.38
Design of the cooperative study on glycemic control and complications in diabetes mellitus type 2: Veterans Affairs Diabetes Trial. J Diabetes Complications (2003) 3.33
GC-MS libraries for the rapid identification of metabolites in complex biological samples. FEBS Lett (2005) 3.29
Randomized trial of warfarin, aspirin, and clopidogrel in patients with chronic heart failure: the Warfarin and Antiplatelet Therapy in Chronic Heart Failure (WATCH) trial. Circulation (2009) 3.18
The comparative assessment and improvement of quality of surgical care in the Department of Veterans Affairs. Arch Surg (2002) 3.03
Radial artery grafts vs saphenous vein grafts in coronary artery bypass surgery: a randomized trial. JAMA (2011) 3.03
Long-term patency of saphenous vein and left internal mammary artery grafts after coronary artery bypass surgery: results from a Department of Veterans Affairs Cooperative Study. J Am Coll Cardiol (2004) 2.99
An auxin gradient and maximum in the Arabidopsis root apex shown by high-resolution cell-specific analysis of IAA distribution and synthesis. Plant Cell (2009) 2.97
Association of perioperative β-blockade with mortality and cardiovascular morbidity following major noncardiac surgery. JAMA (2013) 2.82
Timing of surgical antibiotic prophylaxis and the risk of surgical site infection. JAMA Surg (2013) 2.82
Operative blood loss, blood transfusion, and 30-day mortality in older patients after major noncardiac surgery. Ann Surg (2010) 2.80
Percutaneous coronary intervention versus coronary bypass surgery in United States veterans with diabetes. J Am Coll Cardiol (2013) 2.79
Outcomes after esophagectomy: a ten-year prospective cohort. Ann Thorac Surg (2003) 2.73
Identifying patient preoperative risk factors and postoperative adverse events in administrative databases: results from the Department of Veterans Affairs National Surgical Quality Improvement Program. J Am Coll Surg (2002) 2.73
Comparison of laparoscopic and open repair with mesh for the treatment of ventral incisional hernia: a randomized trial. Arch Surg (2010) 2.58
Survival among high-risk patients after bariatric surgery. JAMA (2011) 2.57
Nutrient modification of the innate immune response: a novel mechanism by which saturated fatty acids greatly amplify monocyte inflammation. Arterioscler Thromb Vasc Biol (2010) 2.42
High-throughput data analysis for detecting and identifying differences between samples in GC/MS-based metabolomic analyses. Anal Chem (2005) 2.38
Successful implementation of the Department of Veterans Affairs' National Surgical Quality Improvement Program in the private sector: the Patient Safety in Surgery study. Ann Surg (2008) 2.34
Astrocytic complexity distinguishes the human brain. Trends Neurosci (2006) 2.26
Autonomic contribution to blood pressure and metabolism in obesity. Hypertension (2006) 2.25
Cost-effectiveness of coronary artery bypass grafts versus percutaneous coronary intervention for revascularization of high-risk patients. Circulation (2006) 2.24
The patient safety in surgery study: background, study design, and patient populations. J Am Coll Surg (2007) 2.22
Use of national surgical quality improvement program data as a catalyst for quality improvement. J Am Coll Surg (2007) 2.18
The use of zoledronic acid in men receiving androgen deprivation therapy for prostate cancer with severe osteopenia or osteoporosis. Urology (2010) 2.14
Extraction and GC/MS analysis of the human blood plasma metabolome. Anal Chem (2005) 2.13
Impact of obesity on outcomes after open surgical and endovascular abdominal aortic aneurysm repair. J Am Coll Surg (2009) 2.12
Surgical outcomes for patients aged 80 and older: morbidity and mortality from major noncardiac surgery. J Am Geriatr Soc (2005) 2.12
Sterol-dependent endocytosis mediates post-cytokinetic acquisition of PIN2 auxin efflux carrier polarity. Nat Cell Biol (2008) 2.09
Transplantation of cardiac progenitor cell sheet onto infarcted heart promotes cardiogenesis and improves function. Cardiovasc Res (2010) 2.06
Patient risk factors, operative care, and outcomes among older community-dwelling male veterans with hip fracture. J Bone Joint Surg Am (2008) 2.06
Autoantibodies to oxidized LDL and cardiovascular risk: the Framingham Offspring Study. Atherosclerosis (2006) 2.04
Left ventricular remodeling and ventricular arrhythmias after myocardial infarction. Circulation (2003) 2.03
Design of experiments: an efficient strategy to identify factors influencing extraction and derivatization of Arabidopsis thaliana samples in metabolomic studies with gas chromatography/mass spectrometry. Anal Biochem (2004) 2.02
Predictive indices of morbidity and mortality after liver resection. Ann Surg (2006) 2.01
Time of day is associated with postoperative morbidity: an analysis of the national surgical quality improvement program data. Ann Surg (2008) 2.00
Unscheduled readmissions to the PICU: epidemiology, risk factors, and variation among centers. Pediatr Crit Care Med (2013) 1.99
Research leadership and investigators: gender distribution in the federal government. Am J Med (2012) 1.98
Preoperative risks and outcomes of hip and knee arthroplasty in the Veterans Health Administration. J Arthroplasty (2003) 1.97
The Vietnam Era Twin Registry. Twin Res (2002) 1.95
Operative outcomes beyond 30-day mortality: colorectal cancer surgery in oldest old. Ann Surg (2011) 1.93
Gender differences in advanced heart failure: insights from the BEST study. J Am Coll Cardiol (2003) 1.91
Assessment of ACS NSQIP's predictive ability for adverse events after major cancer surgery. Ann Surg Oncol (2010) 1.88
Impact of body mass index on perioperative outcomes in patients undergoing major intra-abdominal cancer surgery. Ann Surg Oncol (2008) 1.88
Predictors and outcomes of a perioperative myocardial infarction following elective vascular surgery in patients with documented coronary artery disease: results of the CARP trial. Eur Heart J (2008) 1.87
Gulf War veterans' health: medical evaluation of a U.S. cohort. Ann Intern Med (2005) 1.86
Potential cost savings of erythropoietin administration in end-stage renal disease. Am J Med (2002) 1.83
Intensive glucose-lowering therapy reduces cardiovascular disease events in veterans affairs diabetes trial participants with lower calcified coronary atherosclerosis. Diabetes (2009) 1.83
Seasonal variation in surgical outcomes as measured by the American College of Surgeons-National Surgical Quality Improvement Program (ACS-NSQIP). Ann Surg (2007) 1.81
A strategy for identifying differences in large series of metabolomic samples analyzed by GC/MS. Anal Chem (2004) 1.80
Exenatide suppresses postprandial elevations in lipids and lipoproteins in individuals with impaired glucose tolerance and recent onset type 2 diabetes mellitus. Atherosclerosis (2010) 1.80
GA4 is the active gibberellin in the regulation of LEAFY transcription and Arabidopsis floral initiation. Plant Cell (2006) 1.77
The plant stress hormone ethylene controls floral transition via DELLA-dependent regulation of floral meristem-identity genes. Proc Natl Acad Sci U S A (2007) 1.74
Macrophage-secreted factors induce adipocyte inflammation and insulin resistance. Biochem Biophys Res Commun (2006) 1.74
Racial/ethnic differences in surgical outcomes in veterans following knee or hip arthroplasty. Arthritis Rheum (2005) 1.72
The attributable risk of smoking on surgical complications. Ann Surg (2011) 1.71
Effects of acute hypoglycemia on inflammatory and pro-atherothrombotic biomarkers in individuals with type 1 diabetes and healthy individuals. Diabetes Care (2010) 1.71
Comparison of efficacy and safety of rosuvastatin versus atorvastatin in African-American patients in a six-week trial. Am J Cardiol (2005) 1.71
DITPA (3,5-Diiodothyropropionic Acid), a thyroid hormone analog to treat heart failure: phase II trial veterans affairs cooperative study. Circulation (2009) 1.70
Health expenditures among high-risk patients after gastric bypass and matched controls. Arch Surg (2012) 1.69
National Surgical Quality Improvement Program (NSQIP) risk factors can be used to validate American Society of Anesthesiologists Physical Status Classification (ASA PS) levels. Ann Surg (2006) 1.69
Multivariable predictors of postoperative respiratory failure after general and vascular surgery: results from the patient safety in surgery study. J Am Coll Surg (2007) 1.68